UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F56F3.3	F56F3.3	3e-65	chrIII 4,458,938	contains similarity to Drosophila dasycnemia Wingless (Fragment).; TR:O46305
2	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	sru-35	C33D9.4	n/a	chrIV 8,789,328	C. elegans SRU-35 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
4	F16B4.6	F16B4.6	n/a	chrV 1,588,179	contains similarity to Pfam domain PF00550 Phosphopantetheine attachment site contains similarity to Interpro domains IPR006163 (Phosphopantetheine-binding), IPR009081 (Acyl carrier protein-like), IPR003231 (Acyl carrier protein (ACP))
5	gly-14	M01F1.1	n/a	chrIII 3,491,809	gly-14 encodes a UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta-1, 2-N-acetylglucosaminyltransferase I (GnT 1); GLY-14 exhibits GnT 1 activity when assayed in vitro; a gly-14::lacZ reporter construct is expressed only in the intestine throughout larval and adult stages, with expression generally restricted to the anterior and posterior gut cells.
6	srx-76	K12G11.5	n/a	chrV 11,892,608	C. elegans SRX-76 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
7	cpb-1	C40H1.1	n/a	chrIII 9,323,513	cpb-1 encodes a cytoplasmic polyadenylation element binding (CPEB) protein homolog involved in two steps of spermatogenesis; two CPEB proteins have distinct functions in spermatogenesis, with FOG-1 specifying sperm cell fate, and CPB-1 conversely executing that decision, being required for progression through meiosis; cpb-1(RNAi) spermatocytes fail to undergo meiotic cell divisions; CPB-1 protein is present in the germ line just prior to overt spermatogenesis, but once sperm differentiation begins, CPB-1 disappears; CPB-1 physically interacts with EBF, which, like CPEB, regulates genes by binding the 3' UTRs of mRNAs; while CPB-1 is required for spermatogenesis, it is dispensable for oogenesis; this is in contrast to CPEBs in vertebrates (Xenopus), arthropods (Drosophila), and molluscs (Spisula), which all participate in oogenesis.
8	T04G9.6	T04G9.6	n/a	chrX 783,076	contains similarity to Interpro domain IPR001759 (Pentaxin)
9	F18A12.6	F18A12.6	n/a	chrII 3,401,335	F18A12.6 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; F18A12.6 has no clear orthologs in other organisms.
10	T23F1.5	T23F1.5	n/a	chrV 15,461,926	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR001507 (Endoglin/CD105 antigen)
11	srbc-48	F54B8.6	n/a	chrV 15,820,807	C. elegans SRBC-48 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
12	fbxb-58	H11E01.1	n/a	chrX 1,628,252	C. elegans FBXB-58 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
13	clec-156	F26A1.11	n/a	chrIII 4,842,010	C. elegans CLEC-156 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000694 (Proline-rich region), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
14	C28F5.1	C28F5.1	n/a	chrII 7,506,343
15	hlh-4	T05G5.2	n/a	chrIII 9,738,064	C. elegans HLH-4 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR015660 (Achaete-scute transcription factor related), IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR000694 (Proline-rich region), IPR011598 (Helix-loop-helix DNA-binding)
16	gly-15	C54C8.11	n/a	chrI 12,463,985	gly-15 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; gly-15 expressed only in cellular processes that are probably part of the secretory network of the G2 gland cells.
17	T28A11.4	T28A11.4	n/a	chrV 3,274,213
18	rbx-2	R10A10.2	n/a	chrI 6,421,299	The R10A10.2 gene encodes an ortholog of the mammalian zinc RING finger protein SAG, which protects cells from apoptosis induced by redox agents and is a component of ubiquitin-ligase (E3) complexes; mammalian SAG binds to the yeast Cul1 protein, complements the lethality of a mutation in yeast Sag, and (when bound to yeast Cul1) has ubiquitin ligase activity and promotes poly-ubiquitination of E2/Cdc34.
19	F46B3.1	F46B3.1	n/a	chrV 20,592,082	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
20	grd-8	C37C3.4	n/a	chrV 7,843,402	grd-8 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity proline-rich domain, and a C-terminal Ground domain; GRD-8 is expressed in larval intestine and neurons; the grd-8 gene is directly bound by DAF-12 and requires DAF-12 for full transcription; GRD-8's Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-8 is weakly required for normal molting; GRD-8 is also required for normal adult alae formation, growth to full size, locomotion, and male tail development; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
21	W07G1.1	W07G1.1	n/a	chrII 13,938,717	contains similarity to Pfam domain PF03607 Doublecortin contains similarity to Interpro domain IPR003533 (Doublecortin)
22	srj-8	T28A11.9	n/a	chrV 3,248,476	C. elegans SRJ-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	lgc-51	F12B6.3	n/a	chrI 2,244,756	C. elegans LGC-51 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR002289 (Gamma-aminobutyric-acid A receptor, beta subunit), IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
24	hlh-14	C18A3.8	n/a	chrII 5,738,759	hlh-14 encodes a basic helix-loop-helix (bHLH) transcription factor that is one of five C. elegans Achaete-Scute family homologs; HLH-14 activity is required generally for normal egg-laying, movement, body morphology, and larval development; more specifically, HLH-14 is required for proper neuronal development, particularly for regulation of the asymmetric cell division that gives rise to the PVQ/HSN/PHB neuroblasts and for normal differentiation of these neuroblast descendants, including their cell division patterns, migrations, and neurotransmitter expression; in specifying neuronal cell fates, genetic evidence suggests that hlh-14 acts together with hlh-2, which encodes the C. elegans E/Daughterless ortholog; HLH-14 is expresed exclusively in the embryo and detected in the left and right PVQ/HSN/PHB neuroblasts and their descendants, as well as in other cells identified, tentatively, as anterior neuroblasts and posterior neuroblasts such as Caapa.
25	C04B4.5	C04B4.5	n/a	chrX 12,287,929	contains similarity to Plasmodium falciparum Ring-infected erythrocyte surface antigen precursor.; TR:Q8I0U6
26	T02G6.4	T02G6.4	n/a	chrI 11,811,897	contains similarity to Buchnera aphidicola RpoD protein (EC 2.7.7.6).; TR:Q89AY7
27	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
28	F56D5.9	F56D5.9	n/a	chrIV 9,420,446	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001357 (BRCT)
29	cyp-13B2	K06G5.2	n/a	chrX 14,227,001	C. elegans CYP-13B2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
30	B0041.1	B0041.1	n/a	chrI 4,665,314
31	C25A1.15	C25A1.15	n/a	chrI 10,197,447	contains similarity to Human herpesvirus 6 Hypothetical protein.; TR:Q89893
32	ZK1086.3	ZK1086.3	n/a	chrX 13,791,278	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
33	F59D6.6	F59D6.6	n/a	chrV 3,036,408	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
34	F54H5.3	F54H5.3	n/a	chrII 6,622,759	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
35	M04C7.3	M04C7.3	n/a	chrI 8,546,387	contains similarity to Brucella melitensis Exopolyphosphatase (EC 3.6.1.11).; TR:Q8YCD4
36	srt-36	F47D2.5	n/a	chrV 4,267,330	C. elegans SRT-36 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
37	C23H4.4	C23H4.4	n/a	chrX 12,231,444	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR000062 (Thymidylate kinase), IPR002018 (Carboxylesterase, type B)
38	scl-26	C50E3.10	n/a	chrV 7,601,057	C. elegans SCL-26 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
39	F59H6.2	F59H6.2	n/a	chrII 2,021,048
40	ZK218.11	ZK218.11	n/a	chrV 17,107,962	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
41	F46F5.10	F46F5.10	n/a	chrII 824,543	contains similarity to Pfam domain PF07801 Protein of unknown function (DUF1647) contains similarity to Interpro domain IPR012444 (Protein of unknown function DUF1647)
42	fbxa-30	ZC47.4	n/a	chrIII 1,275,041	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
43	srt-47	Y41E3.12	n/a	chrIV 15,051,352	C. elegans SRT-47 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR006121 (Heavy metal transport/detoxification protein)
44	ric-19	C32E8.7	n/a	chrI 3,779,897	The ric-19 gene encodes an evolutionarily conserved cytosolic protein involved in neuroendocrine secretion via association with secretory vesicles.
45	clec-39	T25E12.7	n/a	chrV 16,740,408	C. elegans CLEC-39 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
46	F46F5.1	F46F5.1	n/a	chrII 790,983
47	str-97	F10A3.8	n/a	chrV 16,154,443	C. elegans STR-97 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
48	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
49	C18B12.1	C18B12.1	n/a	chrX 15,012,725	contains similarity to Bacillus anthracis Flagellar biosynthetic protein FlhB, putative.; TR:Q81SE5
50	clec-46	F07C4.9	n/a	chrV 7,637,516	C. elegans CLEC-46 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)