UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ced-6	F56D2.7	0	chrIII 5,596,872	ced-6 encodes an Src homology (SH) 3 and phosphotyrosine-binding (PTB) domain-containing adaptor protein, orthologous to human CED-6/GULP, that is required for cell corpse engulfment during apoptosis; CED-6 is bound by the phosphotyrosine binding motif in the cytoplasmic tail of the transmembrane protein CED-1, and and within phagocytic cells this interaction may be part of a signal transduction pathway that promotes apoptotic cell engulfment.
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	sru-42	C55A1.8	n/a	chrV 15,651,414	C. elegans SRU-42 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR002208 (SecY protein), IPR003839 (Protein of unknown function DUF215)
4	ttr-53	T14G10.3	n/a	chrIV 10,158,369	C. elegans TTR-53 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
5	sdz-15	F23F12.4	n/a	chrIII 6,499,273	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	srw-61	H25K10.7	n/a	chrIV 16,237,697	C. elegans SRW-61 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor)
7	C26B2.8	C26B2.8	n/a	chrIV 8,014,864	contains similarity to Interpro domains IPR008914 (Phosphatidylethanolamine-binding protein PEBP), IPR006150 (Cysteine-rich repeat)
8	C10A4.2	C10A4.2	n/a	chrX 7,412,571
9	wve-1	R06C1.3	n/a	chrI 11,927,136	wve-1 encodes a homolog of the mammalian WAVE protein; based on homology WVE-1 might be involved in actin cytoskeletal dynamics; wve-1 is required for early cell migrations in the epidermis during embryonic morphogenesis and may require gex-2 and gex-3 for its function.
10	B0261.7	B0261.7	n/a	chrI 5,270,246
11	R11.1	R11.1	n/a	chrX 16,192,348	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
12	F37D6.3	F37D6.3	n/a	chrI 10,487,009	contains similarity to Interpro domain IPR002004 (Polyadenylate-binding protein/Hyperplastic disc protein)
13	his-65	H02I12.7	n/a	chrIV 11,401,254	his-65 encodes an H2A histone.
14	his-62	F55G1.3	n/a	chrIV 7,486,714	his-62 encodes an H2B histone.
15	F20D12.2	F20D12.2	n/a	chrIV 7,951,094	contains similarity to Pfam domain PF03399 SAC3/GANP/Nin1/mts3/eIF-3 p25 family contains similarity to Interpro domain IPR005062 (SAC3/GANP/Nin1/mts3/eIF-3 p25)
16	fcd-2	Y41E3.9	n/a	chrIV 15,031,338	fcd-2 encodes an ortholog of the human gene FANCD2 (mutated in Fanconi anemia, OMIM:227646) that is strongly required for resistance to DNA interstrand crosslinking (ICL) agents, but not to ionizing radiation (IR); fcd-2 mutants are viable and dispensable for resistance to IR, meiotic recombination, and S-phase checkpoint activation, but are hypersensitive to ICL agents; like its human ortholog, FCD-2 is monoubiquitylated and recruited to chromosomal foci after ICL but not IR; transgenic expresssion of the FANCD2 gene in mutant FA-D2 cells rescues their abnormal sensitivity to mitomycin C, an agent that cross-links strands of DNA.
17	dnj-24	W03A5.7	n/a	chrIII 5,417,808	This gene encodes a protein containing a DnaJ ('J') domain.
18	C43E11.11	C43E11.11	n/a	chrI 4,251,319	contains similarity to Homo sapiens Isoform 1 of Conserved oligomeric Golgi complex component 5; ENSEMBL:ENSP00000334703
19	C16C2.4	C16C2.4	n/a	chrI 9,714,017	contains similarity to Pfam domain PF03909 BSD domain contains similarity to Interpro domain IPR005607 (BSD)
20	trxr-1	C06G3.7	n/a	chrIV 7,014,256	C06G3.7 encodes an homolog of the mammalian thioredoxin reductase isozymes TR1 and TR2; like its mammalian homologs, C06G3.7 has a TGA-encoded C-terminal penultimate selenocysteine (Sec) residue; labelling of C. elegans with selenium-75 demonstrates that TR-Se is the major naturally occurring selenoprotein in C. elegans, and computational analysis indicates that it is probably the only selenoprotein encoded by the genome; the 3'-untranslated region of this gene contains a selenocysteine insertion sequence that is functional in mammalian cell culture; by phylogenetic profiling, C06G3.7 protein is predicted to be mitochondrial.
21	F26F4.6	F26F4.6	n/a	chrIII 4,892,477	contains similarity to Homo sapiens Similar to Suppressor protein SRP40; VG:OTTHUMP00000170311
22	math-37	R52.9	n/a	chrII 2,121,460	C. elegans MATH-37 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
23	M03F4.4	M03F4.4	n/a	chrX 4,957,667
24	ZC513.2	ZC513.2	n/a	chrV 8,055,592	contains similarity to Pfam domain PF01273 LBP / BPI / CETP family, N-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
25	T24B8.2	T24B8.2	n/a	chrII 9,055,661	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
26	efl-1	Y102A5C.18	n/a	chrV 16,962,099	efl-1 encodes a homolog of mammalian E2F that is required for embryonic asymmetry and that functions as a transcriptional repressor; during vulval development, efl-1, a class B synMuv gene, acts with class B synMuv genes dpl-1 and lin-35/Rb to antagonize receptor tyrosine kinase and Ras-mediated signaling; EFL-1 also negatively regulates the G1 to S phase cell cycle transition.
27	nhr-179	F16B4.11	n/a	chrV 1,616,853	C. elegans NHR-179 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
28	hpr-17	F32A11.2	n/a	chrII 13,155,162	C. elegans HPR-17 protein; contains similarity to Pfam domain PF03215 Rad17 cell cycle checkpoint protein contains similarity to Interpro domains IPR004582 (Checkpoint protein Rad24), IPR003593 (AAA+ ATPase, core)
29	R105.1	R105.1	n/a	chrIV 4,635,811	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
30	mce-1	D2030.5	n/a	chrI 7,582,722	C. elegans MCE-1 protein; contains similarity to Pfam domain PF00903 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily contains similarity to Interpro domain IPR004360 (Glyoxalase/bleomycin resistance protein/dioxygenase)
31	his-63	F22B3.2	n/a	chrIV 11,406,611	his-63 encodes an H3 histone; by homology, HIS-63 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-63 is a replication-dependent histone locus.
32	ndx-9	F13H10.2	n/a	chrIV 11,010,995	The ndx-9 gene encodes a member of the NADH pyrophosphatase subfamily of the NUDIX hydrolases.
33	F59A3.4	F59A3.4	n/a	chrI 5,508,149	contains similarity to Pfam domain PF02535 ZIP Zinc transporter contains similarity to Interpro domain IPR003689 (Zinc/iron permease)
34	H25P19.1	H25P19.1	n/a	chrV 688,859
35	C04F5.8	C04F5.8	n/a	chrV 5,112,623	contains similarity to Bos taurus Similar to C04F5.8.; TR:Q0IIF4
36	F46C5.7	F46C5.7	n/a	chrII 8,839,705	contains similarity to Homo sapiens Splice isoform 1 of Q8WXQ8 Carboxypeptidase A5 precursor; ENSEMBL:ENSP00000289573
37	R02F11.4	R02F11.4	n/a	chrV 4,814,781	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR008378 (Ubiquitous surface protein), IPR008957 (Fibronectin, type III-like fold), IPR001611 (Leucine-rich repeat), IPR003961 (Fibronectin, type III), IPR003591 (Leucine-rich repeat, typical subtype), IPR009053 (Prefoldin)
38	C53D6.7	C53D6.7	n/a	chrIV 9,035,988	contains similarity to Pfam domain PF00337 Galactoside-binding lectin contains similarity to Interpro domains IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
39	C45G9.7	C45G9.7	n/a	chrIII 5,046,619	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domains IPR017268 (Tax1-binding protein 3), IPR001478 (PDZ/DHR/GLGF)
40	his-60	F55G1.11	n/a	chrIV 7,487,766	his-60 encodes an H4 histone; by homology, HIS-60 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-60 expression is detected in early embryos, beginning at the 28-cell stage and continuing through the comma stage (early morphogenesis); his-60 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
41	F49F1.7	F49F1.7	n/a	chrIV 4,124,635	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
42	K08C7.7	K08C7.7	n/a	chrIV 10,665,006	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
43	his-34	F17E9.9	n/a	chrIV 8,336,138	his-34 encodes an H2B histone; his-34 is contained within the histone gene cluster HIS5.
44	C50D2.5	C50D2.5	n/a	chrII 98,671	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1), IPR002343 (Paraneoplastic encephalomyelitis antigen)
45	F58G1.6	F58G1.6	n/a	chrII 12,941,277	contains similarity to Pfam domain PF02752 Arrestin (or S-antigen), C-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal)
46	C34F6.5	C34F6.5	n/a	chrX 11,208,547	contains similarity to Homo sapiens Histone acetyltransferase MORF beta; ENSEMBL:ENSP00000287239
47	F38B2.3	F38B2.3	n/a	chrX 11,283,730	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
48	ZC376.3	ZC376.3	n/a	chrV 14,169,887	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
49	pph-6	C34C12.3	n/a	chrIII 3,464,667	C. elegans PPH-6 protein; contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
50	sra-29	F18C5.8	n/a	chrII 6,575,011	C. elegans SRA-29 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)