UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	efn-4	F56A11.3	0	chrIV 563,657	efn-4 encodes a member of the ephrin family of ligands that affects neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; can interact with VAB-1 in vitro, and is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
2	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
3	ZK563.5	ZK563.5	n/a	chrX 3,378,206	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17A46
4	C26B9.6	C26B9.6	n/a	chrX 5,334,221	contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF02825 (WWE domain) (2)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR004170 (WWE), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
5	mop-25.2	Y53C12A.4	n/a	chrII 9,702,750	mop-25.2 encodes a Mo25 protein that inhibits DHC-1 in vivo; MOP-25.2 is orthologous to fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.2 is paralogous to MOP-25.1 and (more distantly) MOP-25.3; mop-25.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that MOP-25.2 negatively regulates dynein; in early embryos, MOP-25.2 is associated with the midbody and spindle poles after cytokinesis; MOP-25.2 shares a redundant function with MOP-25.1 in fertility and embryonic viability; in mass RNAi assays, MOP-25.2 is required for normal locomotion, body coloration, speed, and body size.
6	ncs-2	F10G8.5	n/a	chrI 10,034,037	C. elegans NCS-2 protein; contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR001125 (Recoverin), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR000261 (EPS15 homology (EH))
7	mcm-5	R10E4.4	n/a	chrIII 4,289,788	C. elegans MCM-5 protein; contains similarity to Pfam domain PF00493 MCM2/3/5 family contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR008048 (MCM protein 5), IPR003593 (AAA+ ATPase, core), IPR001208 (MCM)
8	pri-2	W02D9.1	n/a	chrI 12,530,247	pri-2 encodes a homolog of the DNA polymerase alpha-primase subunit C that is required in embryos for the normal timing of embryonic cell divisions (much as DIV-1 is) and for normal mitosis in the germline.
9	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
10	srs-1	W03B1.4	n/a	chrIV 4,358,749	srs-1 encodes a predicted mitochondrial seryl-tRNA synthetase (SerRS), a class II aminoacyl-tRNA synthetase that catalyzes the attachment of serine to its cognate tRNA and is thus required for protein biosynthesis; in C. elegans, SRS-1 activity is required for normal postembryonic morphology and rates of growth.
11	T05B4.8	T05B4.8	n/a	chrV 4,115,949	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
12	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
13	eif-3.C	T23D8.4	n/a	chrI 9,978,188	eif-3.C encodes a putative c subunit of translation initiation factor 3 that is required for fertility and for embryonic osmotic integrity; eif-3.C is orthologous to human EIF3S8 (OMIM:603916) and budding yeast NIP1.
14	F31D5.1	F31D5.1	n/a	chrII 4,220,835	contains similarity to Pfam domain PF05978 Eukaryotic protein of unknown function (DUF895) contains similarity to Interpro domains IPR010291 (Protein of unknown function DUF895, eukaryotic), IPR003976 (Potassium channel, two pore-domain, TREK), IPR016196 (MFS general substrate transporter)
15	Y116A8C.40	Y116A8C.40	n/a	chrIV 17,147,619	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	K09E3.6	K09E3.6	n/a	chrX 17,114,487	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
17	T14F9.2	T14F9.2	n/a	chrX 2,235,334
18	C14F11.2	C14F11.2	n/a	chrX 6,211,298	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (6), PF00307 (Calponin homology (CH) domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding), IPR003590 (Leucine-rich repeat, ribonuclease inhibitor subtype)
19	T26A5.6	T26A5.6	n/a	chrIII 6,449,449	contains similarity to Interpro domain IPR001194 (DENN)
20	prx-14	R07H5.1	n/a	chrIV 11,183,588	C. elegans PRX-14 protein; contains similarity to Pfam domain PF04695 Peroxisomal membrane anchor protein (Pex14p) conserved region contains similarity to Interpro domain IPR006785 (Peroxisome membrane anchor protein Pex14p, N-terminal)
21	hst-2	C34F6.4	n/a	chrX 11,205,546	hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad.
22	K04F10.7	K04F10.7	n/a	chrI 6,367,224	contains similarity to Homo sapiens Isoform 1 of Protein FAM76B; ENSEMBL:ENSP00000351631
23	T05A12.3	T05A12.3	n/a	chrIV 6,885,597	contains similarity to Cryptosporidium parvum Iowa II Large low complexity coiled coil protien with large repeat region.; TR:Q5CQL9
24	F11A5.6	F11A5.6	n/a	chrV 16,203,986	contains similarity to Bradyrhizobium japonicum Bll7368 protein.; TR:Q89DS1
25	T11F1.6	T11F1.6	n/a	chrII 2,945,352	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
26	T05G5.4	T05G5.4	n/a	chrIII 9,749,322	contains similarity to Homo sapiens Trichohyalin; ENSEMBL:ENSP00000290632
27	F52D10.2	F52D10.2	n/a	chrX 11,590,643	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
28	C53C11.1	C53C11.1	n/a	chrX 17,340,978	contains similarity to Interpro domain IPR010993 (Sterile alpha motif homology)
29	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
30	R01H2.1	R01H2.1	n/a	chrIII 7,062,968
31	ZK154.5	ZK154.5	n/a	chrX 7,785,505	contains similarity to Homo sapiens Isoform 4 of Target of Nesh-SH3 precursor; ENSEMBL:ENSP00000373190
32	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
33	fbxb-79	R07H5.7	n/a	chrIV 11,189,235	C. elegans FBXB-79 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
34	tat-6	F02C9.3	n/a	chrV 3,131,186	C. elegans TAT-6 protein; contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006539 (Phospholipid-translocating P-type ATPase, flippase), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
35	F44F1.4	F44F1.4	n/a	chrI 13,264,689	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
36	dpm-3	F28D1.11	n/a	chrIV 12,391,825	dpm-3 encodes a putative regulatory subunit of dolichol phosphate mannosyltransferase, orthologous to human DPM3 (OMIM:605951); in mass RNAi assays, DPM-3 is required for normal body size, fertility, and health.
37	F36F12.4	F36F12.4	n/a	chrV 2,089,002	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
38	F53A2.3	F53A2.3	n/a	chrIII 13,338,285	contains similarity to Streptococcus agalactiae Hypothetical protein.; TR:Q8E5X9
39	ZK1098.3	ZK1098.3	n/a	chrIII 9,535,467	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domains IPR002562 (3'-5' exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
40	F08D12.7	F08D12.7	n/a	chrII 2,768,193	F08D12.7 encodes a novel protein conserved amongst Caenorhaditis species; although loss of F08D12.7 activity via RNAi results in no obvious defects, F08D12.7 transcripts are enriched in L1-stage muscle and upregulated in L2 larvae in response to overexpression of hlh-2 and hlh-8; in addition, in analyses of the early embryonic transcriptome, F08D12.7 transcripts are classified as strictly maternal; an F08D12.7::gfp reporter fusion is expressed in the vm1 and vm2 vulval muscles, the intestinal and anal depressor muscles, the hypodermis, distal tip cell, ventral nerve cord, head and tail neurons, and body wall muscle.
41	T21C9.1	T21C9.1	n/a	chrV 10,577,614	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
42	sdz-21	F54E7.5	n/a	chrIII 5,655,941	C. elegans SDZ-21 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
43	fbxb-105	F08D12.8	n/a	chrII 2,770,341	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
44	Y54G11A.11	Y54G11A.11	n/a	chrII 14,350,230	contains similarity to Pfam domain PF05129 Transcription elongation factor Elf1 like contains similarity to Interpro domain IPR007808 (Protein of unknown function DUF701, zinc-binding putative)
45	F56B3.9	F56B3.9	n/a	chrIV 772,200
46	ceh-2	C27A12.5	n/a	chrI 6,048,670	ceh-2 encodes a homeodomain protein homologous to Drosophila empty spiracles (EMS) and the vertebrate EMX1 and EMX2 proteins (OMIM:600034, 600035); although the exact biological role of CEH-2 in C. elegans development and/or behavior is not yet known, expression in pharyngeal neurons and muscle, as well as vulval cells (vulB1, vulB2, and vulC) at late stages of development suggests that CEH-2 may play a role in terminal differentiation events in diverse cell types.
47	Y75B8A.5	Y75B8A.5	n/a	chrIII 12,116,403	contains similarity to Interpro domain IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal)
48	ZK512.1	ZK512.1	n/a	chrIII 9,116,087	contains similarity to Interpro domain IPR007110 (Immunoglobulin-like)
49	srbc-63	T06E6.11	n/a	chrV 15,412,055	C. elegans SRBC-63 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
50	ceh-10	W03A3.1	n/a	chrIII 5,800,012	ceh-10 encodes a member of the Paired-like class of homeodomain proteins; the CEH-10 homeodomain is closely related to the homeodomains of two vertebrate retina proteins (Chx10 from mice and Vsx-1 from goldfish); ceh-10 is required for CAN cell fate specification and migration, complete loss of ceh-10 function results in failure of CAN cell migration and loss of expression of CEH-23 and CEH-10 itself in the CAN and AIY interneurons; CEH-10, along with TTX-3 and CEH-23, constitutes a regulatory cascade of transcription factors that controls all sub-type specific features of the AIY interneurons.