UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F55G11.7	F55G11.7	0	chrIV 12,961,290	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	B0238.1	B0238.1	n/a	chrV 5,241,934	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
4	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	ZK688.2	ZK688.2	n/a	chrIII 7,902,682	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
6	srw-63	Y37A1B.10	n/a	chrIV 14,014,952	C. elegans SRW-63 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
7	Y43E12A.2	Y43E12A.2	n/a	chrIV 10,983,505	contains similarity to Interpro domain IPR001878 (Zinc finger, CCHC-type)
8	R05D3.6	R05D3.6	n/a	chrIII 8,350,531	R05D3.6 encodes the epsilon subunit of the soluble, catalytic F1 portion of ATP synthase (mitochondrial respiratory chain [MRC] complex V); RNAi experiments indicate that loss of R05D3.6 activity has minor effects on growth rate.
9	T22B2.6	T22B2.6	n/a	chrX 3,915,288
10	AC8.4	AC8.4	n/a	chrX 227,022
11	C50A2.2	C50A2.2	n/a	chrIV 1,173,690	contains similarity to Interpro domains IPR000953 (Chromo domain), IPR016197 (Chromo domain-like)
12	F32H5.4	F32H5.4	n/a	chrV 13,362,228	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
13	bcmo-2	F53C3.12	n/a	chrII 3,909,661	C. elegans BCMO-2 protein; contains similarity to Pfam domain PF03055 Retinal pigment epithelial membrane protein contains similarity to Interpro domains IPR004294 (Carotenoid oxygenase), IPR015123 (Bcr-Abl oncoprotein oligomerisation)
14	F19B2.6	F19B2.6	n/a	chrV 20,155,401	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q23A89
15	F07G6.5	F07G6.5	n/a	chrX 1,706,500
16	H10E21.1	H10E21.1	n/a	chrIII 16,729
17	lagr-1	Y6B3B.10	n/a	chrI 13,728,317	C. elegans LAGR-1 protein; contains similarity to Pfam domain PF03798 Longevity-assurance protein (LAG1) contains similarity to Interpro domains IPR016439 (Longevity assurance proteins LAG1/LAC1), IPR005547 (Longevity-assurance protein (LAG1)), IPR006634 (TRAM, LAG1 and CLN8 homology)
18	AC8.3	AC8.3	n/a	chrX 228,920
19	F37C4.2	F37C4.2	n/a	chrIV 3,887,244	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
20	F48F5.2	F48F5.2	n/a	chrV 20,441,470	contains similarity to Homo sapiens Intestinal mucin; TR:O43420
21	abf-4	Y38H6C.22	n/a	chrV 20,553,545	abf-4 encodes a homolog of the antibacterial factor ASABF from Ascaris suum; ABF-4 may play a role in innate immunity, though at present the only evidence for its having an antimicrobial humoral function is its sequence similarity.
22	B0238.13	B0238.13	n/a	chrV 5,245,859	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
23	del-1	E02H4.1	n/a	chrX 14,274,420	del-1 encodes an ion channel protein of the DEG/ENaC (degenerin/epithelial Na+ channel) family; like other members of the degenerin family, DEL-1 is predicted to function as a sensory mechanotransduction channel, however detailed analysis of the DEL-1 mutant phenotype has not yet been reported; DEL-1 is expressed postembryonically in the VA and VB motor neurons and in the FLP sensory neurons; the DEL-1 expression pattern overlaps that of UNC-8, an additional C. elegans degenerin involved in movement control, with which DEL-1 may coassemble to form mechanically activated cation channels.
24	ugt-42	F31F4.7	n/a	chrV 648,465	C. elegans UGT-42 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
25	C12D12.5	C12D12.5	n/a	chrX 3,505,953	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)
26	T21D12.12	T21D12.12	n/a	chrIV 267,384	contains similarity to Pfam domain PF00014 Kunitz/Bovine pancreatic trypsin inhibitor domain contains similarity to Interpro domains IPR002223 (Proteinase inhibitor I2, Kunitz metazoa), IPR006150 (Cysteine-rich repeat)
27	R03H10.7	R03H10.7	n/a	chrII 4,177,232	contains similarity to Pfam domain PF01336 OB-fold nucleic acid binding domain contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR004365 (Nucleic acid binding, OB-fold, tRNA/helicase-type)
28	T08E11.8	T08E11.8	n/a	chrII 1,834,708	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
29	lips-13	T13B5.7	n/a	chrII 1,116,848	C. elegans LIPS-13 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
30	ubc-23	C28G1.1	n/a	chrX 8,846,276	ubc-23 encodes a predicted conjugating enzyme (UBCs/E2s) of the ubiquitin-conjugation system; expressed in larvae and adults in cells around the pharynx and in intestinal cells.
31	F17C8.6	F17C8.6	n/a	chrIII 4,745,411	F17C8.6 encodes an alpha1 Ca2+ channel subunit; large-scale RNAi experiments indicate that during development F17C8.6, along with nca-2, may play a role in regulating egg size and shape.
32	ZK402.2	ZK402.2	n/a	chrX 1,403,926	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
33	T28F3.9	T28F3.9	n/a	chrIV 17,310,065	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
34	Y6B3B.3	Y6B3B.3	n/a	chrI 13,716,143	contains similarity to Interpro domain IPR010133 ()
35	M28.8	M28.8	n/a	chrII 10,630,658	contains similarity to Interpro domain IPR000583 (Glutamine amidotransferase, class-II)
36	Y44F5A.1	Y44F5A.1	n/a	chrIII 4,246,236	contains similarity to Interpro domains IPR017422 (WD repeat protein 55), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
37	H05C05.3	H05C05.3	n/a	chrIII 2,967,980
38	F29B9.11	F29B9.11	n/a	chrIV 4,659,939
39	col-187	C30F2.1	n/a	chrX 16,073,795	C. elegans COL-187 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
40	nep-2	T05A8.4	n/a	chrII 2,721,578	T05A8.4 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; while T05A8.4 is an ortholog of mammalian neutral endopeptidase (NEP), expressed on the brush-border membranes of kidney; more generally, T05A8.4 falls into a group of proteins that includes the classical neprilysins found in mammals (e.g., PEX [OMIM:307800] and the enkephalin cleaving enzymes).
41	R05D7.4	R05D7.4	n/a	chrI 12,182,156	contains similarity to Pfam domains PF07819 (PGAP1-like protein) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR012908 (PGAP1-like), IPR000639 (Epoxide hydrolase-like), IPR008262 (Lipase, active site), IPR003089 (Alpha/beta hydrolase)
42	F45E1.5	F45E1.5	n/a	chrX 7,978,560	contains similarity to Interpro domain IPR000834 (Peptidase M14, carboxypeptidase A)
43	gcy-1	AH6.1	n/a	chrII 9,514,635	gcy-1 is predicted to encode a guanylate cyclase; however, transcriptional fusions of the putative upstream regulatory region with a GFP reporter did not confirm its expression.
44	sulp-4	K12G11.1	n/a	chrV 11,877,220	sulp-4 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-4 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids and when expressed in Xenopus oocytes, SULP-4 exhibits robust transport of sulfate and more modest transport of chloride ions and oxalate; a SULP-4::GFP fusion is expressed in the apical canaliculae of the excretory cell and also in some head neurons.
45	K05G3.1	K05G3.1	n/a	chrX 16,501,554	contains similarity to Pfam domain PF01612 3'-5' exonuclease contains similarity to Interpro domain IPR002562 (3'-5' exonuclease)
46	C46A5.1	C46A5.1	n/a	chrIV 7,765,495	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
47	T05B4.4	T05B4.4	n/a	chrV 4,128,560
48	nhr-180	F31F4.12	n/a	chrV 666,725	C. elegans NHR-180 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
49	M117.3	M117.3	n/a	chrIV 11,823,697	M117.3 can encode a protein with similarity to the C-terminal half of the 14-3-3 proteins PAR-5 and FTT-2, beginning in predicted alpha helix five and continuing through the ends of the proteins; loss of M117.3 activity via large-scale RNAi results in no obvious abnormalities.
50	E04F6.4	E04F6.4	n/a	chrII 7,190,903	contains similarity to Pfam domains PF08371 (Phospholipase D/viral envelope) , PF00614 (Phospholipase D Active site motif) (2)contains similarity to Interpro domains IPR013582 (Phospholipase D/viral envelope), IPR001736 (Phospholipase D/Transphosphatidylase)