UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F55G1.12	F55G1.12	2e-128	chrIV 7,494,554	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
2	lrp-2	T21E3.3	n/a	chrI 3,939,445	C. elegans LRP-2 protein; contains similarity to Pfam domains PF00008 (EGF-like domain) (6), PF07974 (EGF-like domain) , PF00057 (Low-density lipoprotein receptor domain class A) (14), PF00058 (Low-density lipoprotein receptor repeat class B) (7)contains similarity to Interpro domains IPR000033 (), IPR000742 (EGF-like, type 3), IPR006209 (EGF-like), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR015943 (WD40/YVTN repeat-like)
3	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
4	xbx-1	F02D8.3	n/a	chrV 14,981,466	C. elegans XBX-1 protein ; contains similarity to Homo sapiens Isoform 1 of Cytoplasmic dynein 2 light intermediate chain 1; ENSEMBL:ENSP00000260605
5	skr-6	Y37H2C.2	n/a	chrV 18,269,765	The skr-6 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-6(RNAi) animals are at least superficially normal.
6	ocam-1	T02B5.2	n/a	chrV 14,167,452	T02B5.2 encodes a protein with an OCAM domain, a nematode-specific motif conserved between T02B5.2 and two other nematode ONECUT homeobox proteins (CEH-21 and CEH-41); this gene is probably derived from a ONECUT gene that lost both tit cut domain and its homeodomain; T02B5.2 has no obvious function in mass RNAi assays.
7	str-16	Y73C8A.1	n/a	chrV 3,239,764	C. elegans STR-16 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
8	W02B3.3	W02B3.3	n/a	chrIII 668,260
9	F26F2.7	F26F2.7	n/a	chrV 20,581,046	contains similarity to Pfam domain PF05346 Eukaryotic membrane protein family contains similarity to Interpro domain IPR008010 (Protein of unknown function DUF747, CMV receptor)
10	F56H6.9	F56H6.9	n/a	chrI 12,305,199	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
11	EEED8.12	EEED8.12	n/a	chrII 5,408,624	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
12	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
13	F59D12.1	F59D12.1	n/a	chrX 15,669,484	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
14	Y17D7C.2	Y17D7C.2	n/a	chrV 18,717,931	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
15	acr-5	K03F8.2	n/a	chrIII 6,512,172	acr-5 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors that is expressed in the nervous system.
16	srbc-52	F54B8.10	n/a	chrV 15,828,326	C. elegans SRBC-52 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
17	F47F2.2	F47F2.2	n/a	chrX 3,886,480
18	B0391.3	B0391.3	n/a	chrV 15,616,248	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000802 (Arsenical pump membrane protein)
19	str-178	R11D1.5	n/a	chrV 12,715,427	C. elegans STR-178 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	K05F6.8	K05F6.8	n/a	chrII 1,567,541	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	R06B9.4	R06B9.4	n/a	chrII 13,754,197	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
22	C14A6.3	C14A6.3	n/a	chrV 18,147,539	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
23	srx-34	T01C4.4	n/a	chrV 7,119,646	C. elegans SRX-34 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
24	C46H3.3	C46H3.3	n/a	chrX 1,228,487	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
25	dsl-4	F16B12.2	n/a	chrX 14,091,441	dsl-4 encodes a putative secreted protein with a single DSL domain and three EGF domains in series, somewhat like Delta/LAG-2; unlike the nematode-specific family of Delta/LAG-2-like proteins (including DSL-1, -2, -3, -5, -6, and -7), DSL-4 is evolutionarily divergent, with perhaps a distant affinity to APX-1, ARG-1, and LAG-2.
26	lin-11	ZC247.3	n/a	chrI 10,251,797	lin-11 encodes a predicted LIM homeodomain transcription factor that affects vulval development, neuronal development and fate specification, utse cell differentiation, and fertility; it is expressed in some neurons, the vulva, pi cells and their progeny, and the spermatheca.
27	C23F12.3	C23F12.3	n/a	chrX 9,393,106
28	F26H9.2	F26H9.2	n/a	chrI 9,292,112	contains similarity to Pfam domain PF02755 RPEL repeat contains similarity to Interpro domain IPR004018 (RPEL repeat)
29	srbc-83	C31A11.3	n/a	chrV 16,297,797	C. elegans SRBC-83 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR002231 (5-Hydroxytryptamine receptor)
30	tsg-101	C09G12.9	n/a	chrIV 3,512,510	C09G12.9 encodes the C. elegans ortholog of S. cerevisiae vacuolar protein sorting protein Vps23p and human TUMOR SUSCEPTIBILITY GENE 101 (TSG101; OMIM:601387), mutations in which are associated with several types of cancer and with varying responses to HIV infection; the product of C09G12.9 is predicted to be a component of C. elegans ESCRT-1 (Endosomal Sorting Complex Required for Transport), and RNAi experiments indicate that its activity is essential for embryonic and larval development.
31	Y75B8A.19	Y75B8A.19	n/a	chrIII 12,229,214	contains similarity to Lactococcus lactis Signal peptidase I (EC 3.4.21.89).; TR:Q9CDG2
32	C39D10.1	C39D10.1	n/a	chrX 7,906,986
33	F55H12.3	F55H12.3	n/a	chrI 8,884,703	contains similarity to Pfam domains PF00008 (EGF-like domain) (5), PF07645 (Calcium binding EGF domain) , PF07699 (GCC2 and GCC3) (3), PF07974 (EGF-like domain) (5), PF00057 (Low-density lipoprotein receptor domain class A) , PF02494 (HYR domain) , PF00084 (Sushi domain (SCR repeat)) (2)contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR011641 (GCC2 and GCC3), IPR016187 (C-type lectin fold), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR016186 (C-type lectin-like), IPR013032 (EGF-like region, conserved site), IPR001304 (C-type lectin), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding), IPR008985 (Concanavalin A-like lectin/glucanase)
34	math-2	C08F1.1	n/a	chrII 1,799,617	C. elegans MATH-2 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
35	C07A9.12	C07A9.12	n/a	chrIII 9,726,313	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
36	T27F6.7	T27F6.7	n/a	chrI 12,496,077	contains similarity to Timmia bavarica NADH dehydrogenase subunit 4 (Fragment).; TR:Q94YV9
37	F09B12.5	F09B12.5	n/a	chrX 15,086,421	contains similarity to Pfam domain PF00057 Low-density lipoprotein receptor domain class A contains similarity to Interpro domain IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
38	F22H10.5	F22H10.5	n/a	chrX 16,687,280	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
39	C31G12.3	C31G12.3	n/a	chrV 18,185,300	contains similarity to Rhodopirellula baltica Probable polysaccharide export protein.; TR:Q7UYB3
40	C33E10.10	C33E10.10	n/a	chrX 17,301,563	contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
41	sma-3	R13F6.9	n/a	chrIII 6,862,404	sma-3 encodes a Smad protein; during development, SMA-3 functions as part of a DBL-1/SMA-6 TGF-beta-related signaling pathway that controls body size and male tail sensory ray and spicule formation; sma-3 is widely expressed at all developmental stages, beginning during embryogenesis, continuing through all larval stages, and seen very strongly in adult hermaphrodites and males; a SMA-3::GFP is detected in the pharynx, intestine, and hypodermis and localizes to the nucleus; sma-3 expression in the hypodermis is necessary and sufficient for normal body size; SMA-3 can physically interact with the LIN-31 forkhead transcription factor.
42	fpn-1.3	R08F11.6	n/a	chrV 3,796,213	C. elegans FPN-1.3 protein; contains similarity to Pfam domain PF06963 Ferroportin1 (FPN1) contains similarity to Interpro domains IPR009716 (Ferroportin1), IPR016196 (MFS general substrate transporter)
43	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
44	F35E8.2	F35E8.2	n/a	chrV 15,906,320	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DZ81
45	cyp-33E1	C49C8.4	n/a	chrIV 8,646,858	C. elegans CYP-33E1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
46	srt-16	C50H11.11	n/a	chrV 3,064,037	C. elegans SRT-16 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	srxa-16	F44G3.5	n/a	chrV 16,113,637	C. elegans SRXA-16 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
48	srw-39	F19B2.3	n/a	chrV 20,166,056	C. elegans SRW-39 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domain IPR010726 (Protein of unknown function DUF1300)
49	exc-9	F20D12.5	n/a	chrIV 7,940,302	exc-9 encodes a LIM domain-containing protein; exc-9 activity is required for proper development and morphogenesis of the excretory cell canal.
50	smf-2	K11G12.3	n/a	chrX 6,717,366	C. elegans SMF-2 protein; contains similarity to Pfam domain PF01566 Natural resistance-associated macrophage protein contains similarity to Interpro domain IPR001046 (Natural resistance-associated macrophage protein)