UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-61	F55G1.10	9.999999999999999e-43	chrIV 7,485,966	his-61 encodes an H2A histone.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	his-43	F08G2.2	9.999999999999999e-43	chrII 13,827,426	his-43 encodes an H2A histone.
4	his-57	F54E12.5	9.999999999999999e-43	chrIV 11,340,574	his-57 encodes an H2A histone.
5	T17H7.7	T17H7.7	n/a	chrIII 756,721
6	T07C4.10	T07C4.10	n/a	chrIII 10,323,248	contains similarity to Interpro domains IPR002957 (Keratin, type I), IPR000533 (Tropomyosin), IPR009053 (Prefoldin)
7	M195.2	M195.2	n/a	chrII 8,362,076	contains similarity to Pfam domain PF02363 Cysteine rich repeat
8	F22G12.4	F22G12.4	n/a	chrI 13,157,287	contains similarity to Pfam domains PF01363 (FYVE zinc finger) , PF00023 (Ankyrin repeat) (17)contains similarity to Interpro domains IPR000306 (Zinc finger, FYVE-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002110 (Ankyrin), IPR017455 (Zinc finger, FYVE-related), IPR011011 (Zinc finger, FYVE/PHD-type)
9	T24C12.4	T24C12.4	n/a	chrX 2,204,550
10	R10E4.9	R10E4.9	n/a	chrIII 4,302,001	contains similarity to Pfam domain PF04387 Protein tyrosine phosphatase-like protein, PTPLA contains similarity to Interpro domain IPR007482 (Protein-tyrosine phosphatase-like, PTPLA)
11	his-48	B0035.8	n/a	chrIV 11,324,941	his-48 encodes an H2B histone; by homology, HIS-48 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-48 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
12	his-33	F17E9.13	9.999999999999999e-43	chrIV 8,335,508	his-33 encodes an H2A histone; by homology, HIS-33 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-33 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
13	fbxa-51	T12B5.1	n/a	chrIII 962,902	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
14	F59F4.3	F59F4.3	n/a	chrX 15,844,928	contains similarity to Interpro domain IPR002038 (Osteopontin)
15	F56D1.2	F56D1.2	n/a	chrII 5,476,416	contains similarity to Pfam domain PF08357 SEFIR domain contains similarity to Interpro domain IPR013568 (SEFIR)
16	gpdh-1	F47G4.3	n/a	chrI 14,077,014	gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-1 activity via large-scale RNAi screens results in no obvious defects, gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans.
17	his-66	H02I12.6	n/a	chrIV 11,400,571	his-66 encodes an H2B histone.
18	M05B5.4	M05B5.4	n/a	chrI 7,189,526	The M05B5.4 gene encodes an ortholog of the human gene LECITHIN-CHOLESTEROL ACYLTRANSFERASE (LCAT; OMIM:606967), which when mutated leads to lecithin-cholesterol acyltransferase deficiency (OMIM:245900).
19	his-30	F35H10.1	9.999999999999999e-43	chrIV 8,331,839	his-30 encodes an H2A histone; by homology, HIS-30 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-30 is a replication-dependent histone locus that resides in the HIS5 cluster on chromosome IV.
20	T01D1.3	T01D1.3	n/a	chrII 175,055
21	K09F6.8	K09F6.8	n/a	chrII 2,295,399
22	ulp-2	Y38A8.3	n/a	chrII 4,957,746	C. elegans ULP-2 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
23	K09F6.3	K09F6.3	n/a	chrII 2,258,704	contains similarity to Pfam domains PF02206 (Domain of unknown function) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR003125 (Protein of unknown function WSN)
24	pps-1	T14G10.1	n/a	chrIV 10,163,166	pps-1 is orthologous to human PAPSS1 (OMIM:603262) and human PAPSS2 (OMIM:603005, mutated in spondyloepimetaphyseal dysplasia).
25	H06O01.2	H06O01.2	n/a	chrI 7,012,174	H06O01.2 encodes a large (1,461-aa) putative chromodomain helicase DNA-binding protein that inhibits DHC-1 in vivo; H06O01.2 is orthologous to budding yeast CHD1, human CHD1 (OMIM:602118), and human CHD2 (OMIM:602119); H06O01.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that H06O01.2 negatively regulates dynein; H06O01.2 has no obvious function in mass RNAi assays.
26	C42D4.2	C42D4.2	n/a	chrIV 7,181,781	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
27	T21C9.9	T21C9.9	n/a	chrV 10,591,537	contains similarity to Interpro domain IPR000694 (Proline-rich region)
28	C11D2.3	C11D2.3	n/a	chrIV 6,154,348
29	C15H9.3	C15H9.3	n/a	chrX 6,116,887	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domain IPR000276 (GPCR, rhodopsin-like)
30	T05C12.4	T05C12.4	n/a	chrII 8,178,909	contains similarity to Interpro domain IPR003566 (T-cell surface glycoprotein CD5)
31	dnc-1	ZK593.5	n/a	chrIV 10,929,896	DNC-1 encodes a dynactin, orthologous to Drosophila GLUED, that is required for pronuclear migration and centrosome separation in one-cell embryos and for the correct alignment of mitotic spindles in early embryos; DNC-1 shares embryonic functions with DNC-2, DHC-1, LIS-1 and NUD-1; DNC-1 is located at cortical microtubule attachment sites.
32	T20D4.4	T20D4.4	n/a	chrV 3,416,870	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
33	sri-27	ZK697.4	n/a	chrV 1,726,643	C. elegans SRI-27 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	C09F9.2	C09F9.2	n/a	chrII 14,708,961	contains similarity to Pfam domains PF01390 (SEA domain) , PF01826 (Trypsin Inhibitor like cysteine rich domain) (3), PF07974 (EGF-like domain) , PF03351 (DOMON domain) (4)contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR005018 (DOMON related), IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR000082 (SEA), IPR008960 (Carbohydrate-binding family 9/cellobiose dehydrogenase, cytochrome), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR013050 (DOMON)
35	C08F11.7	C08F11.7	n/a	chrIV 13,637,874	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR002398 (Peptidase C14, caspase precursor p45)
36	F49F1.7	F49F1.7	n/a	chrIV 4,124,635	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
37	T06D8.10	T06D8.10	n/a	chrII 11,244,135	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal), IPR001007 (von Willebrand factor, type C)
38	F55G1.13	F55G1.13	n/a	chrIV 7,496,503	F55G1.13 encodes a protein that contains EGF-like repeats that are most closely related to those of Notch family members.
39	gbh-1	D2089.5	n/a	chrII 10,692,053	gbh-1 encodes a predicted ortholog of human hBBOX1; expressed in the intestine and in head and body muscles.
40	C18B10.6	C18B10.6	n/a	chrV 7,480,150	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
41	C18B2.6	C18B2.6	n/a	chrX 3,615,375	contains similarity to Pfam domain PF00858 Amiloride-sensitive sodium channel contains similarity to Interpro domain IPR001873 (Na+ channel, amiloride-sensitive)
42	T19C3.4	T19C3.4	n/a	chrIII 619,226	contains similarity to Pfam domain PF03134 TB2/DP1, HVA22 family contains similarity to Interpro domain IPR004345 (TB2/DP1 and HVA22 related protein)
43	T20G5.10	T20G5.10	n/a	chrIII 10,211,438	contains similarity to Pfam domain PF06320 GCN5-like protein 1 (GCN5L1) contains similarity to Interpro domain IPR009395 (GCN5-like 1)
44	C56G2.15	C56G2.15	n/a	chrIII 6,367,144	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase), IPR008125 (Streptothricin acetyltransferase)
45	mix-1	M106.1	n/a	chrII 10,832,781	The mix-1 gene encodes a homolog of SMC2 involved in chromosome segregation, X-chromosome gene regulation, and repression of X-linked genes during dosage compensation.
46	K09H11.7	K09H11.7	n/a	chrV 5,752,981	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR006349 (2-phosphoglycolate phosphatase, eukaryotic), IPR005834 (Haloacid dehalogenase-like hydrolase)
47	K08D10.5	K08D10.5	n/a	chrIV 4,168,957	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
48	T23G4.3	T23G4.3	n/a	chrIV 13,686,045	contains similarity to Homo sapiens BAG-family molecular chaperone regulator-4; ENSEMBL:ENSP00000287322
49	F32B4.6	F32B4.6	n/a	chrI 11,516,108	contains similarity to Pfam domains PF07819 (PGAP1-like protein) , PF00561 (alpha/beta hydrolase fold) contains similarity to Interpro domains IPR000073 (Alpha/beta hydrolase fold-1), IPR012908 (PGAP1-like)
50	C33G3.4	C33G3.4	n/a	chrX 14,073,660	C33G3.4 is orthologous to the human gene BETA-MANNOSIDASE (MANBA; OMIM:248510), which when mutated leads to disease.