UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	tag-345	F55F8.5	0	chrI 5,656,990	C. elegans TAG-345 protein; contains similarity to Pfam domains PF08154 (NLE (NUC135) domain) , PF00400 (WD domain, G-beta repeat) (4)contains similarity to Interpro domains IPR012972 (NLE), IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
2	C01G10.10	C01G10.10	n/a	chrV 15,081,298	contains similarity to Pfam domain PF00814 Glycoprotease family contains similarity to Interpro domains IPR009180 (Peptidase M22, O-sialoglycoprotein endopeptidase), IPR000905 (Peptidase M22, glycoprotease)
3	smc-4	F35G12.8	n/a	chrIII 4,590,281	The smc-4 gene encodes a homolog of the SMC4 subunit of mitotic condensin; SMC-4 acts with MIX-1 to enable chromosome segregation.
4	C07D8.6	C07D8.6	n/a	chrX 7,342,092	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
5	ugt-60	C07A9.6	n/a	chrIII 9,677,585	C. elegans UGT-60 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
6	C55A6.9	C55A6.9	n/a	chrV 11,522,512	contains similarity to Pfam domain PF03985 Paf1 contains similarity to Interpro domain IPR007133 (RNA polymerase II-associated, Paf1)
7	T04A8.6	T04A8.6	n/a	chrIII 4,692,695	T04A8.6 encodes an ortholog of S. cerevisiae NOP15 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, T04A8.6 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.
8	F28H6.4	F28H6.4	n/a	chrX 14,130,605	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR012287 (Homeodomain-related), IPR009057 (Homeodomain-like)
9	mel-46	T06A10.1	n/a	chrIV 16,859,204	C. elegans MEL-46 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
10	B0280.9	B0280.9	n/a	chrIII 7,121,829	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR001680 (WD40 repeat), IPR011046 (WD40 repeat-like), IPR015943 (WD40/YVTN repeat-like)
11	gip-2	C45G3.3	n/a	chrI 9,227,490	gip-2 encodes a member of the Biotin/lipoate A/B protein ligase family.
12	T24A6.17	T24A6.17	n/a	chrV 3,564,846
13	F17A9.2	F17A9.2	n/a	chrV 6,111,285	contains similarity to Pfam domains PF04676 (Protein similar to CwfJ C-terminus 2) , PF04677 (Protein similar to CwfJ C-terminus 1) contains similarity to Interpro domains IPR006768 (Protein similar to CwfJ, C-terminal 1), IPR006767 (Protein similar to CwfJ, C-terminal 2), IPR011146 (Histidine triad-like motif)
14	M03C11.8	M03C11.8	n/a	chrIII 10,432,042	contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000330 (SNF2-related), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
15	Y32B12B.2	Y32B12B.2	n/a	chrV 16,544,097	contains similarity to Vitis vinifera Putative uncharacterized protein.; TR:A5AD22
16	F55G1.9	F55G1.9	n/a	chrIV 7,476,741	contains similarity to Pfam domain PF03807 NADP oxidoreductase coenzyme F420-dependent contains similarity to Interpro domains IPR004455 (NADP oxidoreductase, coenzyme F420-dependent), IPR000304 (Delta 1-pyrroline-5-carboxylate reductase), IPR016040 (NAD(P)-binding)
17	B0001.5	B0001.5	n/a	chrIV 12,142,216	contains similarity to Saccharomyces cerevisiae Gtpase-activating protein activity toward the essential bud-site assembly GTPase Cdc42; SGD:YPL115C
18	T28D6.6	T28D6.6	n/a	chrIII 11,334,762	contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF02824 (TGS domain) contains similarity to Interpro domains IPR005225 (Small GTP-binding protein), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR004095 (TGS), IPR006074 (GTP1/OBG, conserved site)
19	ZK1098.7	ZK1098.7	n/a	chrIII 9,523,311	contains similarity to Drosophila melanogaster Flybase gene name is mRpS23-PA;; FLYBASE:CG31842
20	T07F8.4	T07F8.4	n/a	chrII 7,131,218	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR000949 (ELM2)
21	mat-3	F10C5.1	n/a	chrIII 478,879	mat-3 encodes a tetratricopeptide repeat (TPR)-containing protein that is the C. elegans ortholog of CDC23/APC8, a conserved regulatory subunit of the anaphase-promoting complex; mat-3 activity is required for progression through metaphase of oocyte meiosis I, germline proliferation, and vulval development.
22	Y47H9C.8	Y47H9C.8	n/a	chrI 11,895,073	contains similarity to Streptococcus pneumoniae Magnesium transporter, CorA family.; TR:Q97SX8
23	npp-11	F53F10.5	n/a	chrI 3,819,703	C. elegans NPP-11 protein; contains similarity to Interpro domains IPR003072 (Orphan nuclear receptor, NOR1 type), IPR000104 (Antifreeze protein, type I), IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
24	C05C8.2	C05C8.2	n/a	chrV 7,231,951	contains similarity to Interpro domain IPR004087 (K Homology)
25	mog-5	EEED8.5	n/a	chrII 5,402,615	The mog-5 gene encodes a DEAH helicase orthologous to the Drosophila CG8241, the human HRH1, and the S. cerevisiae PRP22 proteins.
26	K08F4.1	K08F4.1	n/a	chrIV 10,124,631	contains similarity to Pfam domain PF00004 ATPase family associated with various cellular activities (AAA) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR001199 (Cytochrome b5), IPR003593 (AAA+ ATPase, core)
27	C03H5.3	C03H5.3	n/a	chrII 387,056	contains similarity to Interpro domain IPR002408 (Natriuretic peptide, brain type)
28	orc-2	F59E10.1	n/a	chrII 10,875,816	C. elegans ORC-2 protein; contains similarity to Pfam domain PF04084 Origin recognition complex subunit 2 contains similarity to Interpro domain IPR007220 (Origin recognition complex subunit 2)
29	C15H11.9	C15H11.9	n/a	chrV 14,424,428	contains similarity to Pfam domain PF04939 Ribosome biogenesis regulatory protein (RRS1) contains similarity to Interpro domain IPR007023 (Ribosomal biogenesis regulatory protein)
30	cyn-11	T01B7.4	n/a	chrII 8,715,669	cyn-11 encodes a divergent cyclophilin D isoform, with alterations in the normally well-conserved cyclophilin-binding domain, and a central 7-8 residue insert not usually found in cyclophilins, except from plants; CYN-11 has sluggish but detectable peptidyl-prolyl isomerase activity in vitro, suggesting that it has a specialized substrate in vivo; CYN-11 is dispensable for viability and gross morphology in mass RNAi screens.
31	nst-1	K01C8.9	n/a	chrII 8,281,963	nst-1 encodes a homolog of human GNL3 (OMIM:608011, nucleostemin) and GNL3L, and of S. cerevisiae NUG1; NST-1 may suppress tumorous growth in the germline; like PRO-1, -2, and -3, NST-1 is probably required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline; nucleostemin is a nucleolar protein found in stem cells that is required in quantitatively correct amounts (neither too little nor too much) for continued cell division and survival by stem cells or transformed cells; NST-1 is required in mass RNAi assays for normally rapid growth, larval viability, and normal body morphology and pigmentation.
32	npp-2	T01G9.4	n/a	chrI 8,292,456	npp-2 encodes a protein with low similarity to rat nucleoporin Nup75 that affects embryonic viability and has a variety of other defects in RNAi screens including: nuclear morphology, growth, fertility, locomotion, and egg laying; enriched in oocytes.
33	lap-1	ZK353.6	n/a	chrIII 8,400,522	The lap-1 gene encodes a homolog of the zinc metalloprotease leucine aminopeptidase LAP that is predicted to be mitochondrial.
34	arx-7	M01B12.3	n/a	chrI 3,069,767	arx-7 encodes the C. elegans ortholog of the p16Arc subunit of the actin-related protein (Arp)2/3 complex.
35	C16C10.2	C16C10.2	n/a	chrIII 4,178,135	contains similarity to Pfam domain PF03998 Utp11 protein contains similarity to Interpro domain IPR007144 (Small-subunit processome, Utp11)
36	F17A9.3	F17A9.3	n/a	chrV 6,106,582	contains similarity to Pfam domain PF07716 Basic region leucine zipper contains similarity to Interpro domains IPR011700 (Basic leucine zipper), IPR004827 (Basic-leucine zipper (bZIP) transcription factor)
37	F10E7.5	F10E7.5	n/a	chrII 7,112,410	contains similarity to Pfam domain PF00466 Ribosomal protein L10 contains similarity to Interpro domain IPR001790 (Ribosomal protein L10)
38	rnf-121	C16C10.5	n/a	chrIII 4,169,952	C. elegans RNF-121 protein; contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
39	T16G12.6	T16G12.6	n/a	chrIII 10,072,699	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
40	K07C5.3	K07C5.3	n/a	chrV 10,344,230	contains similarity to Pfam domain PF00645 Poly(ADP-ribose) polymerase and DNA-Ligase Zn-finger region contains similarity to Interpro domain IPR001510 (Zinc finger, PARP-type)
41	K01C8.6	K01C8.6	n/a	chrII 8,278,000	contains similarity to Drosophila pseudoobscura 39S ribosomal protein L10, mitochondrial precursor (L10mt) (MRP-L10).; SW:Q29NV5
42	evl-14	H38K22.1	n/a	chrIII 4,308,081	evl-14 encodes a homolog of the yeast sister cohesion protein Pds5p that functions during both mitosis and meiosis and is implicated in the maintenance of sister chromatid cohesion in late prophase, and affects vulval morphology, meiotic germline development, embryonic and larval viability, fertility, and cell divisions in the germ line as well as in vulval and somatic gonad lineages; some of the defects, such as somatic gonad defects, are due at least partially to cell division defects.
43	F52C9.7	F52C9.7	n/a	chrIII 5,309,798	contains similarity to Interpro domain IPR002226 (Catalase)
44	F13H6.5	F13H6.5	n/a	chrV 6,373,505	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
45	cya-2	F59H6.7	n/a	chrII 2,023,091	C. elegans CYA-2 protein; contains similarity to Pfam domain PF00134 Cyclin, N-terminal domain contains similarity to Interpro domains IPR006670 (Cyclin), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR006671 (Cyclin, N-terminal)
46	ulp-2	Y38A8.3	n/a	chrII 4,957,746	C. elegans ULP-2 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
47	T10E9.2	T10E9.2	n/a	chrI 6,543,527
48	H01G02.1	H01G02.1	n/a	chrIV 11,803,772
49	C41H7.3	C41H7.3	n/a	chrII 3,006,666	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
50	dylt-1	F13G3.4	n/a	chrI 7,300,621	dylt-1 encodes a putative dynein light chain subunit that inhibits DHC-1 in vivo, but is otherwise dispensable for viability; DYLT-1 is paralogous to DYLT-3, and orthologous to human DYNLT1 and DYNLT3 (OMIM: 300302); dylt-1(RNAi) and dylt-1(ok417) both suppress the lethality of conditional dhc-1 mutations, and dylt-1(RNAi) suppresses dhc-1(or195) spindle length and cytokinesis defects as well, indicating that DYLT-1 negatively regulates dynein; in oocytes and early embryos, DYLT-1 is associated with nuclear envelopes and centrosomes, and with meiotic and mitotic spindle poles; like DHC-1 itself, DYLT-1 is strongly mislocalized to centrosomes in dhc-1(or195) animals shifted to nonpermissive temperature.