UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F55E10.1	F55E10.1	4e-45	chrX 8,342,071
2	F11D11.4	F11D11.4	n/a	chrV 18,762,417	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
3	puf-4	M4.2	n/a	chrIV 3,207,566	C. elegans PUF-4 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
4	ZC412.8	ZC412.8	n/a	chrV 14,879,632	contains similarity to Plasmodium cynomolgi Circumsporozoite protein precursor (CS).; SW:P08675
5	M03F8.5	M03F8.5	n/a	chrV 5,935,209	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
6	F15E6.5	F15E6.5	n/a	chrIV 4,289,807	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
7	C30H6.9	C30H6.9	n/a	chrIV 17,379,717	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81PV8
8	gpa-11	C16A11.1	n/a	chrII 4,254,160	gpa-11 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADL and ASH amphid neurons.
9	aqp-7	M02F4.8	n/a	chrX 3,026,113	aqp-7 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases either water or glycerol permeability five- to seven-fold; AQP-7 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its several paralogs; AQP-7 is expressed in muscle punctae (perhaps focal adhesions).
10	F26F2.3	F26F2.3	n/a	chrV 20,561,363	contains similarity to Saccharomyces cerevisiae Profilin synthetic lethal protein, has region of coiled-coil structure; subunit of the Exocyst complex--the Exocyst complex contains the gene products encoded by SEC3, SEC5, SEC6, SEC8, SEC10, SEC15 and EXO70 and is required for exocytosis; SGD:YER008C
11	sri-65	F13A7.8	n/a	chrV 16,387,488	C. elegans SRI-65 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000883 (Cytochrome c oxidase, subunit I)
12	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
13	F56H6.2	F56H6.2	n/a	chrI 12,288,243	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
14	T22B2.5	T22B2.5	n/a	chrX 3,910,583
15	clec-121	Y25C1A.4	n/a	chrII 3,103,522	C. elegans CLEC-121 protein; contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
16	C18B2.2	C18B2.2	n/a	chrX 3,625,928	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
17	ZK380.4	ZK380.4	n/a	chrX 1,652,654
18	dbl-1	T25F10.2	n/a	chrV 6,759,095	dbl-1 encodes a member of the transforming growth factor beta (TGFbeta) superfamily that includes Drosophila decapentaplegic (Dpp) and the vertebrate bone morphogenetic proteins (BMPs); DBL-1 functions as a dose-dependent ligand for the SMA-6 and DAF-4 TGFbeta receptors that ultimately activate the SMA-2, -3, and -4 complex of transcription factors to regulate body length and size, as well as the patterning of male sensory rays and copulatory spicules; DBL-1 signaling upregulates sma-6 expression, suggesting that there is positive autoregulation in the DBL-1 signaling pathway; in contrast, DBL-1 negatively regulates expression of LON-1, a predicted secreted protein that is a downstream component of the body size pathway; DBL-1 is expressed primarily in neurons.
19	K06H6.4	K06H6.4	n/a	chrV 580,280	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
20	srh-278	T09F5.8	n/a	chrV 15,171,028	C. elegans SRH-278 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	R05A10.5	R05A10.5	n/a	chrIV 14,169,839	contains similarity to Interpro domain IPR000884 (Thrombospondin, type I)
22	F28A10.5	F28A10.5	n/a	chrII 850,172	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
23	F59B2.13	F59B2.13	n/a	chrIII 9,025,413	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
24	fbxa-160	C08E3.12	n/a	chrII 1,624,293	C. elegans FBXA-160 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
25	srb-12	F58A6.10	n/a	chrII 5,153,860	C. elegans SRB-12 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
26	ceh-14	F46C8.5	n/a	chrX 7,530,621	ceh-14 encodes a LIM homeodomain protein orthologous to Drosophila Lim3 and the vertebrate Lhx3 and Lhx4 proteins; ceh-14 is required for specification of the AFD thermosensory neurons and for normal thermotactic behavior; a ceh-14::GFP reporter fusion is expressed in head and tail neurons, including the AFD thermosensory neurons, during late embryonic, larval, and adult stages. Animals triply mutant for the LIM homeobox genes ceh-14, lin-11, and ttx-3 which are required for function of the AFD, AIZ, and AIY neurons, respectively, exhibit a basic cryophilic thermotaxis response suggesting that, in C. elegans, there is more than one pathway for integration of thermosensory input.
27	sra-11	F44F4.13	n/a	chrII 10,909,485	sra-11 encodes an orphan, G protein-coupled seven-transmembrane receptor; SRA-11 is expressed in three classes of interneurons, AIA, AIY, and AVB throughout larval and adult stages, and analysis of sra-11 mutations indicates that sra-11 activity in AIY is essential for olfactory imprinting; sra-11 expression in AIY is positively regulated by the TTX-3 and CEH-23 homeodomain proteins, with TTX-3 required for both initiation and maintenance of expression and CEH-23 required solely for maintenance.
28	fip-5	F41E7.4	n/a	chrX 10,302,828	C. elegans FIP-5 protein; contains similarity to Interpro domain IPR000480 (Glutelin)
29	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
30	ZC482.7	ZC482.7	n/a	chrIII 12,752,251	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
31	str-119	C13B7.5	n/a	chrV 2,427,301	C. elegans STR-119 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	C47F8.4	C47F8.4	n/a	chrI 12,317,914	contains similarity to Pfam domain PF03360 Glycosyltransferase family 43 contains similarity to Interpro domain IPR005027 (Glycosyl transferase, family 43)
33	ZC132.8	ZC132.8	n/a	chrV 4,316,012
34	Y39A1A.2	Y39A1A.2	n/a	chrIII 10,602,626	contains similarity to Oryza sativa Hypothetical protein.; TR:Q9LH25
35	nhr-185	F47C10.1	n/a	chrV 3,845,862	C. elegans NHR-185 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000306 (Zinc finger, FYVE-type), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	C27D6.1	C27D6.1	n/a	chrII 5,174,657	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
37	F56H6.3	F56H6.3	n/a	chrI 12,289,861
38	knl-1	C02F5.1	n/a	chrIII 8,252,399	knl-1 encodes a novel acidic protein with a coiled-coil region at its C-terminus; KNL-1 is an essential kinetochore component that is required for proper spindle elongation and chromosome separation, and in the kinetochore assembly pathway, plays a key role in linking the initiation of kinetochore formation with the construction of a functional microtubule-binding interface; in the assembly pathway, KNL-1 functions downstream of the DNA-proximal kinetochore components CeCENP-A/HCP-3 and CeCENP-B/HCP-4 and upstream of the outer kinetochore components HIM-10/Nuf2p, NDC-80/HEC1, CeBUB-1, HCP-1, and CeCLASP2/CLS-2; in expression studies in the one-cell embryo, KNL-1 localizes to kinetochores throughout mitosis.
39	F41C6.2	F41C6.2	n/a	chrX 6,870,966
40	D1053.4	D1053.4	n/a	chrX 11,722,796	contains similarity to Naja kaouthia Cytotoxin 5 (Cytotoxin II).; SW:CX5_NAJKA
41	F49C12.4	F49C12.4	n/a	chrIV 9,303,356	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
42	C32A9.1	C32A9.1	n/a	chrX 10,259,366	contains similarity to Plasmodium falciparum Hypothetical protein, conserved.; TR:Q8IEA2
43	W03G9.7	W03G9.7	n/a	chrI 4,988,180	contains similarity to Methanocaldococcus jannaschii Chromosome partition protein smc homolog.; SW:Q59037
44	F36D4.1	F36D4.1	n/a	chrV 9,418,520
45	K03D7.9	K03D7.9	n/a	chrV 17,488,056	contains similarity to Homo sapiens Olfactory receptor 1A1; ENSEMBL:ENSP00000305207
46	srh-211	D1065.5	n/a	chrV 4,078,922	C. elegans SRH-211 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
47	K04A8.2	K04A8.2	n/a	chrV 6,563,097	contains similarity to Pfam domain PF03269 Caenorhabditis protein of unknown function, DUF268 contains similarity to Interpro domain IPR004951 (Protein of unknown function DUF268, Caenorhabditis species)
48	F55E10.4	F55E10.4	n/a	chrX 8,327,670
49	ZC477.4	ZC477.4	n/a	chrIV 7,098,647
50	C10E2.5	C10E2.5	n/a	chrX 16,752,685