UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F55D10.4	F55D10.4	1e-128	chrX 4,718,585
2	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
3	srsx-14	C39H7.5	n/a	chrIV 5,625,990	C. elegans SRSX-14 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
4	mif-3	F13G3.9	n/a	chrI 7,313,193	C. elegans MIF-3 protein; contains similarity to Pfam domain PF01187 Macrophage migration inhibitory factor (MIF) contains similarity to Interpro domains IPR014347 (Tautomerase), IPR001398 (Macrophage migration inhibitory factor)
5	sup-9	F34D6.3	n/a	chrII 2,685,863	sup-9 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; sup-9 was originally defined by gain-of-function mutations that result in defects in pharyngeal, body-wall, egg-laying, and enteric muscle activation; loss of sup-9 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that SUP-9 may function redundantly with other TWK channels; SUP-9 is expressed in neurons and muscle.
6	ptr-5	C53C11.3	n/a	chrX 17,322,508	ptr-5 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-5 is weakly required for normal molting from L4 to adult stages; PTR-5 is also required for normal growth to full size and locomotion; PTR-5 is expressed in head and tail neurons, and in ventral nerve cord.
7	fbxa-129	F59A1.8	n/a	chrV 17,656,084	C. elegans FBXA-129 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
8	nhr-7	F54D1.4	n/a	chrIV 11,267,544	C. elegans NHR-7 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000694 (Proline-rich region), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
9	sng-1	T08A9.3	n/a	chrX 7,328,590	sng-1 encodes the C. elegans synaptogyrin ortholog, a vertebrate integral membrane synaptic vesicle protein; loss-of-function mutations in sng-1 result in no obvious defects in synaptogenesis or neuronal activity, suggesting that SNG-1 is likely required for more subtle neuronal functions; SNG-1::GFP reporters are expressed throughout the nervous system in neurons in the dorsal and ventral nerve cords, as well as the anterior nerve ring; SNG-1 colocalizes with the synaptic vesicle component SNT-1.
10	F55C12.6	F55C12.6	n/a	chrII 5,875,271	contains similarity to Pfam domain PF06852 Protein of unknown function (DUF1248) contains similarity to Interpro domain IPR009658 (Protein of unknown function DUF1248)
11	CD4.5	CD4.5	n/a	chrV 5,590,729
12	C12D5.9	C12D5.9	n/a	chrV 7,689,147	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
13	srz-10	ZK1037.11	n/a	chrV 15,308,296	C. elegans SRZ-10 protein ;
14	F07C3.2	F07C3.2	n/a	chrV 9,226,731
15	W04E12.5	W04E12.5	n/a	chrV 19,742,714	contains similarity to Interpro domain IPR000750 (Proenkephalin B)
16	F54D12.7	F54D12.7	n/a	chrII 1,383,599	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
17	rab-14	K09A9.2	n/a	chrX 15,605,871	rab-14 encodes a member of the Rab GTPase family.
18	C38H2.1	C38H2.1	n/a	chrIII 10,369,054	contains similarity to Pfam domains PF00566 (TBC domain) , PF02759 (RUN domain) contains similarity to Interpro domains IPR000195 (RabGAP/TBC), IPR004012 (RUN)
19	F02E11.2	F02E11.2	n/a	chrII 3,267,119
20	T27D1.3	T27D1.3	n/a	chrIII 3,684,552	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR008365 (Prostanoid receptor), IPR001991 (Sodium:dicarboxylate symporter), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR000276 (GPCR, rhodopsin-like)
21	flp-17	C52D10.11	n/a	chrIV 17,191,022	C. elegans FLP-17 protein; contains similarity to Pfam domain PF01581 FMRFamide related peptide family
22	sre-26	Y57A10C.4	n/a	chrII 12,419,774	C. elegans SRE-26 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
23	C35E7.6	C35E7.6	n/a	chrI 10,818,223
24	F33E2.6	F33E2.6	n/a	chrI 12,589,287	contains similarity to Interpro domains IPR006030 (Molluscan rhodopsin C-terminal tail), IPR000694 (Proline-rich region)
25	gab-1	ZC482.1	n/a	chrIII 12,775,682	gab-1 encodes a gamma-aminobutyric acid (GABA) receptor beta-like subunit with both the neurotransmitter-gated ion-channel ligand binding and transmembrane domains; gab-1 can form a GABA-responsive channel when co-expressed with alpha/gamma type subunits in a heterologous expression system; experiments with gab-1 indicate that GABA receptors are involved in the mechanism of resistance to the widely used broad-spectrum anthelmintic drug Ivermectin.
26	R06C1.6	R06C1.6	n/a	chrI 11,950,040	contains similarity to Saccharomyces cerevisiae CCR4 Associated Factor 120 kDa; SGD:YNL278W
27	F55A4.7	F55A4.7	n/a	chrX 1,037,733	contains similarity to Pfam domain PF00402 Calponin family repeat contains similarity to Interpro domain IPR000557 (Calponin repeat)
28	R13A5.9	R13A5.9	n/a	chrIII 7,577,267	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
29	tkr-1	C38C10.1	n/a	chrIII 9,386,535	tkr-1 encodes a G protein-coupled receptor that is the C. elegans tachykinin-like neuropeptide receptor homolog; by homology, TKR-1 is predicted to function in modulation of excitatory neurotransmission; as loss of tkr-1 activity via RNAi results in moderate reduction of fat content, TKR-1 may play a specific role in regulating lipid metabolism; a tkr-1 reporter gene fusion is reportedly expressed in the socket cells of the deirid and post-deirid sensilla from the L2 larval stage through adulthood.
30	VM106R.1	VM106R.1	n/a	chrII 10,828,708	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
31	nhr-39	F44A2.4	n/a	chrV 9,303,947	C. elegans NHR-39 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
32	C18H7.6	C18H7.6	n/a	chrIV 590,772	contains similarity to Interpro domain IPR000817 (Prion protein)
33	Y38H6C.18	Y38H6C.18	n/a	chrV 20,542,275	contains similarity to Saccharomyces cerevisiae Chromatin Assembly Complex, subunit 1: largest (p90) subunit of three-subunit protein complex (yeast CAF-I) involved in DNA-replication-linked nucleosome assembly. Homol. to p150 subunit human Chromatin Assembly Factor-I (CAF-I); SGD:YPR018W
34	unc-9	R12H7.1	n/a	chrX 13,214,484	unc-9 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; UNC-9 is required for normal forward locomotion and egg-laying and also plays a role in the response to antihelminthics and volatile anesthetics; UNC-9 may form a functional pair with UNC-7, another C. elegans innexin, as mutations in unc-7 result in defects nearly identical to those in unc-9 mutant animals.
35	T19D7.5	T19D7.5	n/a	chrX 665,501
36	F23H11.7	F23H11.7	n/a	chrIII 918,259
37	4R79.2	4R79.2	n/a	chrIV 17,481,819	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR006688 (ADP-ribosylation factor), IPR002041 (Ran GTPase), IPR013753 (Ras), IPR006687 (GTP-binding protein SAR1), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR005225 (Small GTP-binding protein), IPR003579 (Ras small GTPase, Rab type)
38	C16D6.1	C16D6.1	n/a	chrX 12,525,704	contains similarity to Interpro domain IPR000694 (Proline-rich region)
39	Y116A8A.6	Y116A8A.6	n/a	chrIV 16,826,929	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
40	ssu-1	Y113G7A.11	n/a	chrV 20,126,167	ssu-1 encodes, by alternative splicing, two isoforms of a cytosolic alcohol sulfotransferase that interacts in the ASJ amphid neurons with the stomatins UNC-1 and UNC-24; the longer SSU-1 isoform is required for normal anesthetic sensitivity and unc-1 phenotypes; ssu-1(fc73) suppresses the anesthetic sensitivity and uncoordinated phenotypes of unc-1 and unc-24 mutants; ssu-1(fc73), along with daf-12, suppresses the synthetic constitutive dauer-formation phenotype of fc83;unc-24(e138) mutants; ssu-1 suppression is rescued by transgenic expression of SSU-1 in the ASJ neurons alone, implying that sulfation is required for an endocrine function; SSU-1 protein sulfates 4-nitrophenol and 2-naphthol substrates, and bisphenol A, but not monoamines or hydroxysteroids; SSU-1 is cytosolic, but its activity is not detectable in cytosolic extracts; ssu-1 is strongly expressed in embryos, growing larvae, and dauer larvae; ssu-1 expression is increased in daf-2; by homology with other sulfotransferases, SSU-1 may link sulfates to the alcohol group of small molecules as part of detoxification or signal transduction.
41	K07E12.2	K07E12.2	n/a	chrIII 6,737,547
42	R01E6.7	R01E6.7	n/a	chrX 13,568,618	contains similarity to Ectocarpus siliculosus virus EsV-1-142.; TR:Q8QKY0
43	C50D2.6	C50D2.6	n/a	chrII 86,096
44	ZC404.7	ZC404.7	n/a	chrV 6,779,108
45	F46F5.4	F46F5.4	n/a	chrII 805,580	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
46	C43F9.5	C43F9.5	n/a	chrIV 10,590,044	contains similarity to Interpro domain IPR006150 (Cysteine-rich repeat)
47	F09C6.3	F09C6.3	n/a	chrV 16,879,465	contains similarity to Saccharomyces cerevisiae DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; SGD:YMR173W
48	str-66	Y73C8C.5	n/a	chrV 3,103,680	C. elegans STR-66 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	Y43F8A.5	Y43F8A.5	n/a	chrV 19,387,467	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
50	Y57A10B.1	Y57A10B.1	n/a	chrII 12,362,805	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)