UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	srx-17	F55B12.8	5e-157	chrV 13,841,443	C. elegans SRX-17 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
2	E01G4.5	E01G4.5	n/a	chrII 13,473,085	contains similarity to Interpro domains IPR002345 (Lipocalin), IPR000215 (Protease inhibitor I4, serpin)
3	Y75B12B.8	Y75B12B.8	n/a	chrV 15,201,905	contains similarity to Homo sapiens Xylosyltransferase I; ENSEMBL:ENSP00000261381
4	C47F8.3	C47F8.3	n/a	chrI 12,315,930	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
5	K02D10.5	K02D10.5	n/a	chrIII 8,777,270	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domain IPR000727 (Target SNARE coiled-coil region)
6	C04B4.4	C04B4.4	n/a	chrX 12,291,546	contains similarity to Saccharomyces cerevisiae Nucleolar protein involved in exit from mitosis; SGD:YJL076W
7	ZK488.5	ZK488.5	n/a	chrV 594,476	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
8	T05H4.3	T05H4.3	n/a	chrV 6,444,929	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal)
9	C11H1.3	C11H1.3	n/a	chrX 14,309,889	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
10	srh-28	ZC404.5	n/a	chrV 6,774,975	C. elegans SRH-28 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	tbx-32	ZK380.1	n/a	chrX 1,656,225	C. elegans TBX-32 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
12	srsx-37	M01B2.7	n/a	chrV 15,258,341	C. elegans SRSX-37 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
13	B0496.4	B0496.4	n/a	chrIV 7,428,290	contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
14	R02E12.5	R02E12.5	n/a	chrX 3,997,923
15	sra-18	F28C12.2	n/a	chrI 12,692,935	C. elegans SRA-18 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
16	sdc-2	C35C5.1	n/a	chrX 11,528,006	The sdc-2 gene encodes a protein that represses transcription of X chromosomes to achieve dosage compensation, and that also represses the male sex-determination gene her-1 to elicit hermaphrodite differentiation.
17	C32B5.6	C32B5.6	n/a	chrII 969,468
18	F29G6.2	F29G6.2	n/a	chrX 11,510,328	contains similarity to Homo sapiens cDNA FLJ43363 fis, clone NT2RP7017474; ENSEMBL:ENSP00000374260
19	hsd-2	ZC8.1	n/a	chrX 5,006,115	The ZC8.1 gene encodes a homolog of the human gene 3BH1, which when mutated leads to giant cell hepatitis (OMIM:231100).
20	rbr-2	ZK593.4	n/a	chrIV 10,923,428	rbr-2 encodes a histone H3 lysine 4 (H3K4) demethylase that is required for normally short lifespan and reliable vulval development, that regulates genome-wide levels of H3K4 trimethylation, and that interacts genetically with CLK-2, GLP-1, LIN-15, and SEM-5; RBR-2 is orthologous to budding yeast Jhd2p, Drosophila LID, and human JARID1A (OMIM:180202), JARID1B (OMIM:605393), JARID1C (OMIM:314690, mutated in mental retardation), and JARID1D (OMIM:426000); rbr-2(tm1231) homozygotes display excess trimethylated H3K4 (H3K4me3) and erratic vulval development (either vulvaless or multivulva); rbr-2(RNAi) animals show extended lifespans, a strong synthetic multivulva and H3K4me3 phenotype in a lin-15(n765ts) mutant background at permissive temperature, and abnormally slow growth with clk-2(mn159), glp-1(or178), or sem-5(n2019) mutant backgrounds.
21	ugt-3	ZC455.3	n/a	chrV 12,799,239	C. elegans UGT-3 protein; contains similarity to Pfam domains PF04101 (Glycosyltransferase family 28 C-terminal domain) , PF00201 (UDP-glucoronosyl and UDP-glucosyl transferase) contains similarity to Interpro domains IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase), IPR007235 (Glycosyl transferase, family 28, C-terminal)
22	sri-71	D2062.3	n/a	chrII 2,628,473	C. elegans SRI-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	C08G5.1	C08G5.1	n/a	chrII 736,664	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
24	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
25	T20D4.9	T20D4.9	n/a	chrV 3,404,051	T20D4.9 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; T20D4.9 has no clear orthologs in other organisms.
26	T22H9.1	T22H9.1	n/a	chrV 361,718	contains similarity to Pfam domain PF06102 Domain of unknown function (DUF947) contains similarity to Interpro domain IPR009292 (Protein of unknown function DUF947)
27	ZK1067.2	ZK1067.2	n/a	chrII 9,218,954	contains similarity to Pfam domain PF01422 NF-X1 type zinc finger contains similarity to Interpro domains IPR000967 (Zinc finger, NF-X1-type), IPR000694 (Proline-rich region), IPR001555 (Phosphoribosylglycinamide formyltransferase, active site), IPR000169 (Peptidase, cysteine peptidase active site)
28	cyp-14A4	R04D3.1	n/a	chrX 13,283,058	C. elegans CYP-14A4 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
29	F10C2.3	F10C2.3	n/a	chrV 12,022,395	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
30	T26G10.1	T26G10.1	n/a	chrIII 9,405,416	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR000629 (RNA helicase, ATP-dependent, DEAD-box, conserved site), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014014 (RNA helicase, DEAD-box type, Q motif), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
31	C23H4.2	C23H4.2	n/a	chrX 12,221,143	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR002018 (Carboxylesterase, type B)
32	C15C8.7	C15C8.7	n/a	chrV 12,744,584	contains similarity to Rhizobium loti Hypothetical protein mll2265.; TR:Q98IT0
33	srbc-67	T24A6.10	n/a	chrV 3,539,627	C. elegans SRBC-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
34	atf-6	F45E6.2	n/a	chrX 12,482,840	atf-6 is an ortholog of mammalian ATF6alpha, a proximal sensor required for the unfolded protein response (UPR) in the endoplasmic reticulum (ER); ATF6alpha is a transmembrane protein, with a bZIP transcription factor domain in its cytosolic amino terminus that is released and activated by proteolytic cleavage upon ER stress; either ire-1 or xbp-1 deletions are synthetically lethal with atf-6 or pek-1 deletions, producing arrest in L2 larvae; RNAi of Y56A3A.2 (a S2P protease homolog) is synthetically lethal with ire-1(RNAi), consistent with the hypothesis that Y56A3A.2 cleaves ATF-6; atf-6 regulates few genes that are transcriptionally induced by UPR, but regulates roughly one-quarter of genes that require UPR constitutively; pdr-1 transcripts are strongly upregulated in a atf-6(ok551) mutant background, but atf-6(ok551);pdr-1(lg103) double mutants have a grossly normal phenotype ; atf-6 is dispensable for proper localization of GLR-1 glutamate receptors.
35	F58D2.1	F58D2.1	n/a	chrIV 13,184,996	contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR016024 (Armadillo-type fold)
36	C06E2.2	C06E2.2	n/a	chrX 8,879,967
37	C09G5.8	C09G5.8	n/a	chrII 10,723,744	contains similarity to Mus musculus Protein fantom (RPGR-interacting protein 1-like protein) (RPGRIP1-likesprotein).; SW:Q8CG73
38	C10C6.6	C10C6.6	n/a	chrIV 11,476,280	contains similarity to Pfam domains PF00122 (E1-E2 ATPase) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR008250 (E1-E2 ATPase-associated region), IPR006069 (ATPase, P-type cation exchange, alpha subunit), IPR006544 (P-type ATPase of unknown pump specificity (type V)), IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter), IPR005834 (Haloacid dehalogenase-like hydrolase)
39	M04C9.2	M04C9.2	n/a	chrI 9,347,132	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
40	fbxb-20	ZC204.9	n/a	chrII 1,649,687	fbxb-20 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-20 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
41	nhr-72	C17A2.8	n/a	chrII 3,849,882	C. elegans NHR-72 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
42	K06H6.5	K06H6.5	n/a	chrV 577,400	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
43	Y59C2A.2	Y59C2A.2	n/a	chrII 2,201,637	contains similarity to Interpro domain IPR000694 (Proline-rich region)
44	nhr-215	T07C5.4	n/a	chrX 12,699,419	C. elegans NHR-215 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
45	C49A1.5	C49A1.5	n/a	chrI 14,239,274	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
46	K03H4.1	K03H4.1	n/a	chrV 13,151,458	contains similarity to Helicobacter pylori Transposase OrfB.; TR:Q93C83
47	srw-59	H24D24.1	n/a	chrV 15,950,332	C. elegans SRW-59 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
48	srg-25	T09D3.5	n/a	chrV 5,343,042	C. elegans SRG-25 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
49	str-209	F26G5.5	n/a	chrV 4,949,965	C. elegans STR-209 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	C05C9.3	C05C9.3	n/a	chrX 11,148,023	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).