UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	mes-1	F54F7.5	0	chrX 11,859,856	The mes-1 gene encodes a receptor tyrosine kinase-like protein that is required for unequal cell divisions in the early embryonic germline; during embryonic cell divisions, mes-1 is involved in positioning of the early mitotic spindle and of associated P granules.
2	srg-4	T12A2.12	n/a	chrIII 6,261,094	C. elegans SRG-4 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
3	uri-1	C55B7.5	n/a	chrI 6,495,201	uri-1 encodes a molecular chaperone orthologous to the unconventional prefoldin RPB5 (RNA polymerase subunit 5) interactor, URI; in C.elegans, URI-1 activity is required for suppressing endogenous genotoxic DNA damage and thus, is essential for maintenance of genome integrity (DNA stability) and progression through the mitotic and meiotic cell cycles, particularly during germ cell development; URI-1 activity is also required for development of some somatic structures, such as the vulva, and for RNA interference; uri-1 mRNA is germline-enriched.
4	srbc-7	C18B10.4	n/a	chrV 7,486,852	C. elegans SRBC-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
5	Y40B1B.7	Y40B1B.7	n/a	chrI 13,427,466	contains similarity to Rattus norvegicus Coiled-coil domain-containing protein 86 (Cytokine-induced proteinswith coiled-coil domain).; SW:Q5XIB5
6	R08D7.5	R08D7.5	n/a	chrIII 8,974,466	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand)
7	F36H12.2	F36H12.2	n/a	chrIV 5,275,375
8	F57G8.7	F57G8.7	n/a	chrV 16,329,811	contains similarity to Antarctic bacterium str 643 Metalloproteinase precursor.; TR:Q9KH34
9	str-244	C50H11.9	n/a	chrV 3,058,396	C. elegans STR-244 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	tbx-36	ZK829.5	n/a	chrIV 11,951,305	C. elegans TBX-36 protein; contains similarity to Pfam domain PF00907 T-box contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR001699 (Transcription factor, T-box)
11	K04F1.10	K04F1.10	n/a	chrV 1,663,542	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000494 (EGF receptor, L domain)
12	F49C5.5	F49C5.5	n/a	chrII 12,546,186
13	C39E9.11	C39E9.11	n/a	chrIV 13,092,485	C39E9.11 is orthologous to the human gene PAPILLARY RENAL CELL CARCINOMA (TRANSLOCATION-ASSOCIATED) (PRCC; OMIM:179755), which when mutated leads to disease.
14	kup-1	F10C2.2	n/a	chrV 12,036,541	kup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.
15	M151.3	M151.3	n/a	chrII 3,629,023	contains similarity to Homo sapiens Isoform 2 of Girdin; ENSEMBL:ENSP00000263630
16	srh-52	R08H2.7	n/a	chrV 15,375,587	C. elegans SRH-52 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
17	his-74	W05B10.1	n/a	chrV 12,659,997	C. elegans HIS-74 protein; contains similarity to Pfam domain PF00125 Core histone H2A/H2B/H3/H4 contains similarity to Interpro domains IPR000164 (Histone H3), IPR009072 (Histone-fold), IPR007125 (Histone core)
18	C46F4.1	C46F4.1	n/a	chrX 5,933,527	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
19	T12F5.2	T12F5.2	n/a	chrI 3,732,139
20	gei-12	F52D2.4	n/a	chrX 1,988,059	gei-12 encodes a novel protein that affects embryonic viability and development of the hypodermis; interacts with GEX-3 in yeast two-hybrid assays, and is expressed in all somatic cells.
21	K11B4.2	K11B4.2	n/a	chrI 14,798,156	contains similarity to Tetraodon nigroviridis UPF0402 protein.; SW:Q4S3C1
22	T24E12.3	T24E12.3	n/a	chrII 3,776,733
23	C49F5.3	C49F5.3	n/a	chrX 11,983,268	contains similarity to Phytophthora infestans SECY-independent transporter protein.; TR:Q9T238
24	C48C5.3	C48C5.3	n/a	chrX 8,959,409	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
25	srb-3	C27D6.8	n/a	chrII 5,166,058	C. elegans SRB-3 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
26	F42A6.5	F42A6.5	n/a	chrIV 3,331,304	contains similarity to Interpro domain IPR001357 (BRCT)
27	pstk-1	Y49E10.22	n/a	chrIII 12,467,328	C. elegans PSTK-1 protein; contains similarity to Pfam domain PF08433 Chromatin associated protein KTI12 contains similarity to Interpro domain IPR013641 (Chromatin associated protein KTI12)
28	T23B12.1	T23B12.1	n/a	chrV 8,469,517	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
29	twk-32	F53C11.6	n/a	chrV 13,798,574	C. elegans TWK-32 protein; contains similarity to Pfam domains PF00041 (Fibronectin type III domain) (2), PF07885 (Ion channel) (2)contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR009147 (Cystic fibrosis transmembrane conductance regulator), IPR013099 (Ion transport 2)
30	fbxa-185	F47H4.4	n/a	chrV 17,333,561	C. elegans FBXA-185 protein; contains similarity to Pfam domains PF01485 (IBR domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type)
31	F44F4.9	F44F4.9	n/a	chrII 10,915,378	contains similarity to Toxoplasma gondii Membrane skeletal protein IMC1.; TR:Q962H9
32	F35H10.6	F35H10.6	n/a	chrIV 8,300,273	contains similarity to Pfam domain PF02996 Prefoldin subunit contains similarity to Interpro domains IPR004127 (Prefoldin alpha-like), IPR009053 (Prefoldin)
33	F20G4.2	F20G4.2	n/a	chrI 7,914,259	contains similarity to Saccharomyces cerevisiae Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; SGD:YER190W
34	F52C6.4	F52C6.4	n/a	chrII 1,923,563	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
35	nhr-177	F16B4.1	n/a	chrV 1,611,519	C. elegans NHR-177 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	M01E11.3	M01E11.3	n/a	chrI 5,574,995	contains similarity to Pfam domain PF08585 Domain of unknown function (DUF1767) contains similarity to Interpro domain IPR013894 (Region of unknown function DUF1767)
37	dro-1	F53A2.5	n/a	chrIII 13,342,882	C. elegans DRO-1 protein; contains similarity to Pfam domains PF00808 (Histone-like transcription factor (CBF/NF-Y) and archaeal histone) , PF00125 (Core histone H2A/H2B/H3/H4) contains similarity to Interpro domains IPR009072 (Histone-fold), IPR007125 (Histone core), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
38	T19H5.2	T19H5.2	n/a	chrII 9,475,595	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001176 (1-aminocyclopropane-1-carboxylate synthase), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
39	ekl-5	Y26E6A.1	n/a	chrX 13,915,941	C. elegans EKL-5 protein; contains similarity to Interpro domains IPR001579 (Glycoside hydrolase, chitinase active site), IPR006642 (Zinc finger, Rad18-type putative)
40	bath-27	F14D2.1	n/a	chrII 3,360,782	C. elegans BATH-27 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
41	hop-1	C18E3.8	n/a	chrI 4,209,468	hop-1 encodes one of three C. elegans presenilins (the other two presenilins are encoded by sel-12 and spe-4); originally identified on the basis of its sequence similarity to SEL-12 and the human PS1 and PS2 presenilins, HOP-1 has been shown to function redundantly with SEL-12 in embryonic, larval, and germline development and thus, to likely function by regulating LIN-12/GLP-1 signaling; in addition, hop-1 can functionally substitute for sel-12 by rescuing the egg-laying and vulval development defects of sel-12 mutants; hop-1 transcription appears to be regulated, at least in part, by the C. elegans spr genes, some of which encode orthologs of the mammalian CoREST repressor complex.
42	T08D2.7	T08D2.7	n/a	chrX 186,625	contains similarity to Pfam domains PF00069 (Protein kinase domain) , PF00498 (FHA domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR008984 (SMAD/FHA domain), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000253 (Forkhead-associated)
43	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
44	srb-12	F58A6.10	n/a	chrII 5,153,860	C. elegans SRB-12 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
45	hum-1	F29D10.4	n/a	chrI 8,848,443	hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures.
46	mes-6	C09G4.5	n/a	chrIV 8,512,584	mes-6 encodes a WD repeat-containing protein that is orthologous to Drosophila Extra sex combs (Esc); as a member of a Polycomb-like chromatin repressive complex with MES-2 and MES-3, MES-6 is required maternally for normal germline development and during larval development, for anteroposterior patterning; during germline development, the MES-2/MES-3/MES-6 complex is believed to be essential for maintaining repression of the X chromosome, and in transgenic animals, the complex is necessary for germline repression of repetitive transgenes; in axial patterning, the MES-2/MES-3/MES-6 complex is required in somatic tissues for maintaining homeotic gene repression, acting upstream of the Hox genes lin-39, mab-5, and egl-5, as well as the egl-5 target gene lin-32; MES-6 expression is detected in the nuclei of all cells during early embryogenesis, in the germline precursors Z2 and Z3 and faintly in some somatic cells during late embryogenesis and the L1 larval stage, widely in later larvae, and in germline and oocyte nuclei in adults; normal MES-6 distribution is dependent upon wild-type activity of MES-2 and MES-3, and likewise, distribution of MES-3 is dependent upon wild-type activity of MES-2 and MES-6
47	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
48	B0393.6	B0393.6	n/a	chrIII 4,781,174	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
49	H05L14.2	H05L14.2	n/a	chrI 7,987,359	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000694 (Proline-rich region), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
50	M05D6.2	M05D6.2	n/a	chrII 8,469,058	contains similarity to Pfam domain PF05794 T-complex protein 11 contains similarity to Interpro domain IPR008862 (T-complex 11)