UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F54F7.2	F54F7.2	2e-178	chrX 11,844,424
2	srg-4	T12A2.12	n/a	chrIII 6,261,094	C. elegans SRG-4 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
3	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
4	B0304.2	B0304.2	n/a	chrII 4,524,073
5	C27D9.1	C27D9.1	n/a	chrII 4,754,512	contains similarity to Pfam domain PF06542 Protein of unknown function (DUF1114) contains similarity to Interpro domain IPR009497 (Protein of unknown function DUF1114)
6	bath-41	F37A4.9	n/a	chrIII 6,721,274	The F37A4.9 gene encodes a protein with a meprin-associated Traf homology (MATH) domain that may be involved in apoptosis.
7	F17C11.10	F17C11.10	n/a	chrV 10,963,667	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR009071 (High mobility group box, HMG), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
8	C27C12.3	C27C12.3	n/a	chrX 14,864,682	C27C12.3 encodes a novel protein that is conserved in C. elegans; three other genes related to C27C12.3 are present in tandem on the X chromosome; in situ hybridization studies indicate that C27C12.3 mRNA is expressed in the proximal germline.
9	C08F8.3	C08F8.3	n/a	chrIV 11,155,803	contains similarity to Gallus gallus Dosal neuron-tube nuclear protein.; TR:Q8QHJ7
10	M01E11.3	M01E11.3	n/a	chrI 5,574,995	contains similarity to Pfam domain PF08585 Domain of unknown function (DUF1767) contains similarity to Interpro domain IPR013894 (Region of unknown function DUF1767)
11	R10D12.12	R10D12.12	n/a	chrV 13,961,624	contains similarity to Pfam domain PF04101 Glycosyltransferase family 28 C-terminal domain contains similarity to Interpro domain IPR007235 (Glycosyl transferase, family 28, C-terminal)
12	R02F2.4	R02F2.4	n/a	chrIII 5,485,028	R02F2.4 encodes a protein with six chitin-binding peritrophin-A domains; R02F2.4 transcripts are enriched during oogenesis; like CEJ-1 and CPG-2, R02F2.4 might participate in eggshell synthesis and early embryonic development, and R02F2.4's multiple peritrophin-A domains might enable mechanical cross-linking of chitin; however, R02F2.4 has no obvious function in mass RNAi assays; while R02F2.4 is more closely similar to CPG-2 than CEJ-1, it may be less strongly expressed (since it has substantially fewer ESTs) and thus be less important in development.
13	E02H9.7	E02H9.7	n/a	chrIII 2,445,442	contains similarity to Homo sapiens Uncharacterized protein MUC17 (Fragment); ENSEMBL:ENSP00000368750
14	W01A8.5	W01A8.5	n/a	chrI 7,070,051	contains similarity to Interpro domain IPR009057 (Homeodomain-like)
15	fut-3	F59E12.13	n/a	chrII 5,658,783	C. elegans FUT-3 protein; contains similarity to Pfam domain PF00852 Glycosyltransferase family 10 (fucosyltransferase) contains similarity to Interpro domain IPR001503 (Glycosyl transferase, family 10)
16	ZK287.7	ZK287.7	n/a	chrV 9,693,782	contains similarity to Homo sapiens Isoform 2 of RNA pseudouridylate synthase domain-containing protein 3; ENSEMBL:ENSP00000380410
17	try-1	ZK546.15	n/a	chrII 4,948,807	C. elegans TRY-1 protein; contains similarity to Pfam domain PF00089 Trypsin contains similarity to Interpro domains IPR001314 (Peptidase S1A, chymotrypsin), IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR009003 (Peptidase, trypsin-like serine and cysteine), IPR008256 (Peptidase S1B, glutamyl endopeptidase I)
18	gei-12	F52D2.4	n/a	chrX 1,988,059	gei-12 encodes a novel protein that affects embryonic viability and development of the hypodermis; interacts with GEX-3 in yeast two-hybrid assays, and is expressed in all somatic cells.
19	C50E3.13	C50E3.13	n/a	chrV 7,623,254
20	F32D1.6	F32D1.6	n/a	chrV 4,374,245
21	fem-3	C01F6.4	n/a	chrIV 9,106,267	fem-3 encodes a novel protein that promotes male development in all tissues.
22	R10E4.6	R10E4.6	n/a	chrIII 4,294,138
23	C16C10.1	C16C10.1	n/a	chrIII 4,180,220	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domains IPR002067 (Mitochondrial carrier protein), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001993 (Mitochondrial substrate carrier), IPR002113 (Adenine nucleotide translocator 1)
24	D1054.3	D1054.3	n/a	chrV 10,772,116	contains similarity to Pfam domains PF04969 (CS domain) , PF05002 (SGS domain) contains similarity to Interpro domains IPR007699 (SGS), IPR008978 (HSP20-like chaperone), IPR017447 (CS), IPR007052 (CS domain)
25	ZC477.5	ZC477.5	n/a	chrIV 7,102,332
26	C31H1.8	C31H1.8	n/a	chrIV 5,812,882	contains similarity to Homo sapiens Protocadherin 15; ENSEMBL:ENSP00000378832
27	T24C4.5	T24C4.5	n/a	chrIII 878,584	contains similarity to Pfam domain PF01896 Eukaryotic and archaeal DNA primase small subunit contains similarity to Interpro domains IPR014052 (DNA primase, small subunit, eukaryotic and archaeal), IPR002755 (DNA primase, small subunit)
28	C29G2.1	C29G2.1	n/a	chrV 2,591,466
29	pfn-1	Y18D10A.20	n/a	chrI 12,922,763	C. elegans PFN-1 protein; contains similarity to Pfam domain PF00235 Profilin contains similarity to Interpro domains IPR002097 (Profilin/allergen), IPR005455 (Profilin, plant)
30	fsn-1	C26E6.5	n/a	chrIII 4,938,358	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins
31	let-99	K08E7.3	n/a	chrIV 12,569,200	let-99 encodes a protein with a DEP domain (Domain found in Dishevelled, Egl-10, and Pleckstrin); LET-99 has no obvious homologs in non-nematodes, but has a truncated paralog (LRG-1) in C. elegans; LET-99 is required for the mitotic spindle to be properly oriented with respect to the axis of cellular polarity, both during anterior migration and rotation of the nuclear-centrosome complex and during anaphase; let-99 mutants exhibit hyperactive nuclear movement and abnormal anaphase spindle pole behavior; LET-99 is mislocalized in par-2 and par-3 mutants; like other proteins containing DEP domains, LET-99 may act as part of a G protein signalling pathway (e.g., the one controlling spindle position).
32	uri-1	C55B7.5	n/a	chrI 6,495,201	uri-1 encodes a molecular chaperone orthologous to the unconventional prefoldin RPB5 (RNA polymerase subunit 5) interactor, URI; in C.elegans, URI-1 activity is required for suppressing endogenous genotoxic DNA damage and thus, is essential for maintenance of genome integrity (DNA stability) and progression through the mitotic and meiotic cell cycles, particularly during germ cell development; URI-1 activity is also required for development of some somatic structures, such as the vulva, and for RNA interference; uri-1 mRNA is germline-enriched.
33	C27A7.6	C27A7.6	n/a	chrV 12,126,221	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
34	K09E3.7	K09E3.7	n/a	chrX 17,132,904	contains similarity to Homo sapiens Conserved hypothetical protein; HI:HIT000048720
35	zyg-11	C08B11.1	n/a	chrII 8,019,153	zyg-11 encodes a protein containing four diverged leucine-rich repeats and an armadillo-like helical domain and is conserved in metazoa, but not found in Drosophila; during development, ZYG-11 functions as the substrate-recognition subunit for a CUL-2-based ubiquitin-ligase complex that is required for a number of biological processes including progression through meiotic anaphase II, mitotic chromosome condensation, and establishment of anterior/posterior polarity in the early embryo; ZYG-11 interacts with CUL-2 in vivo and with ELC-1/elongin C in vitro.
36	B0464.6	B0464.6	n/a	chrIII 9,464,196	contains similarity to Xenopus laevis MGC83764 protein.; TR:Q6DFD0
37	mes-1	F54F7.5	n/a	chrX 11,859,856	The mes-1 gene encodes a receptor tyrosine kinase-like protein that is required for unequal cell divisions in the early embryonic germline; during embryonic cell divisions, mes-1 is involved in positioning of the early mitotic spindle and of associated P granules.
38	C17F4.5	C17F4.5	n/a	chrII 3,247,215	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
39	B0507.7	B0507.7	n/a	chrV 8,757,284	contains similarity to Pfam domains PF04960 (Glutaminase) , PF00023 (Ankyrin repeat) (2)contains similarity to Interpro domains IPR015868 (Glutaminase, core), IPR007043 (Glutaminase), IPR012338 (Beta-lactamase-type transpeptidase fold), IPR002110 (Ankyrin)
40	T09B4.1	T09B4.1	n/a	chrI 6,186,762	contains similarity to Pfam domain PF04188 Mannosyltransferase (PIG-V)) contains similarity to Interpro domain IPR007315 (Mannosyltransferase, PIG-V)
41	sru-48	T03G11.2	n/a	chrX 5,180,802	C. elegans SRU-48 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
42	F11C1.2	F11C1.2	n/a	chrX 12,986,446	contains similarity to Lactococcus lactis Rgg protein, putative.; TR:O87251
43	C25A11.1	C25A11.1	n/a	chrX 9,120,170
44	T19H5.1	T19H5.1	n/a	chrII 9,473,432	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core)
45	zfp-2	F35H8.3	n/a	chrII 9,558,501	zfp-2 encodes a zinc-finger transcription factor; loss of zfp-2 and lin-35/Rb results in almost complete sterility accompanied by defects in somatic gonad development and vulval morphology, as well as polyploidization of somatic cell nuclei; loss of zfp-2 activity by itself reveals that zfp-2 is also required for cosuppression, inhibition of RNAi of some genes, and wild-type levels of expression of a rol-6 extrachromosomal array; a zfp-2::GFP promoter fusion construct is expressed in vulval cells and all somatic gonad structures, such as the spermatheca, sheath cells, uterine cells and distal tip cells (DTCs).
46	F59A6.5	F59A6.5	n/a	chrII 5,001,644	contains similarity to Pfam domains PF00169 (PH domain) , PF00780 (CNH domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR000533 (Tropomyosin), IPR001180 (Citron-like), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding)
47	msh-5	F09E8.3	n/a	chrIV 13,159,611	msh-5 encodes a germline-specific homolog of the yeast and mammalian DNA mismatch repair protein MSH5 (MutS-family) that is required for crossing over and chiasma formation during Caenorhabditis elegans meiosis; inactivation of both rad-51 and msh-5 induces chromosome fragmentation, not seen with inactivation of either gene alone.
48	srh-141	T08G3.5	n/a	chrV 16,444,803	C. elegans SRH-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	dnj-3	C01G10.12	n/a	chrV 15,069,055	This gene encodes a protein containing a DnaJ ('J') domain.
50	kca-1	C10H11.10	n/a	chrI 4,760,571	C. elegans KCA-1 protein ;