UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	rcn-1	F54E7.7	5e-110	chrIII 5,683,173	rcn-1 encodes a calcipressin, which binds and inhibits calcineurin; RCN-1's orthologs include yeast Rcn1p and human DSCR1 (OMIM:602917; overexpressed in Down syndrome and Alzheimer disease); rcn-1 is expressed in hypodermal seam cells, various neurons, vulval epithelial and muscle cells, marginal pharyngeal cells, and in the male tail; rcn-1 transcription is regulated by TAX-6, and RCN-1 binds TAX-6 protein if free Ca[2+] is present; RCN-1 overexpression, like calcineurin deficiency, causes defects in body size, cuticle thickness, fertility, growth rate, and serotonin-resistance in egg-laying.
2	B0524.5	B0524.5	n/a	chrIII 1,892,549	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000352916
3	F27C1.10	F27C1.10	n/a	chrI 5,435,347
4	F09F7.1	F09F7.1	n/a	chrIII 5,575,295
5	F21D12.5	F21D12.5	n/a	chrII 7,329,535	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
6	K09H11.6	K09H11.6	n/a	chrV 5,735,411
7	sre-54	C50E10.6	n/a	chrII 12,333,899	C. elegans SRE-54 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000366 (Fungal pheromone mating factor STE2 GPCR)
8	C24D10.8	C24D10.8	n/a	chrIV 5,165,608	n/a
9	F35B3.3	F35B3.3	n/a	chrX 17,013,662
10	Y54E5A.2	Y54E5A.2	n/a	chrI 14,694,856	contains similarity to Interpro domain IPR000345 (Cytochrome c heme-binding site)
11	F23D12.3	F23D12.3	n/a	chrX 14,442,916
12	acl-12	C01C10.3	n/a	chrX 7,440,941	C. elegans ACL-12 protein; contains similarity to Interpro domain IPR002123 (Phospholipid/glycerol acyltransferase)
13	unc-46	C04F5.3	n/a	chrV 5,098,120	unc-46 encodes a novel protein with a single predicted transmembrane domain; UNC-46 and UNC-47, a novel transmembrane vesicular GABA transporter, are required in GABAergic neurons for all GABA neurotransmission, specifically for loading of GABA into synaptic vesicles, where UNC-46 is localized; UNC-46 localization requires UNC-47, which when overexpressed can rescue unc-46 mutant animals.
14	kin-23	W04G5.6	n/a	chrI 11,641,436	kin-23 encodes a predicted protein tyrosine kinase; like KIN-30, KIN-23 contains an unusual K to R substitution in kinase subdomain VII; kin-23 mRNA is expressed strongly during the L1/L2 larval stages, weakly in L3 and L4 stages, and at undetectable levels in adults.
15	F11D5.6	F11D5.6	n/a	chrX 3,325,709
16	ZC15.1	ZC15.1	n/a	chrV 20,302,899	contains similarity to Interpro domains IPR001878 (Zn-finger, CCHC type), IPR000345 (Cytochrome c heme-binding site)
17	srv-10	F53F1.9	n/a	chrV 13,424,568	C. elegans SRV-10 protein; contains similarity to Interpro domain IPR001411 (Tetracycline resistance protein, TetB)
18	T24A6.2	T24A6.2	n/a	chrV 3,558,528
19	F55C9.6	F55C9.6	n/a	chrV 19,295,191	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domain IPR003366 (CUB-like region)
20	str-47	F07C4.1	n/a	chrV 7,646,392	C. elegans STR-47 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
21	F33D11.6	F33D11.6	n/a	chrI 5,845,654
22	F16H6.7	F16H6.7	n/a	chrV 18,208,098	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
23	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
24	C17B7.2	C17B7.2	n/a	chrV 3,349,796	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
25	ZC443.4	ZC443.4	n/a	chrV 12,818,211	contains similarity to Homo sapiens Isoform 4 of AT-rich interactive domain-containing protein 4B; ENSEMBL:ENSP00000375729
26	R160.5	R160.5	n/a	chrX 4,370,650
27	srj-15	Y40B10B.2	n/a	chrV 1,963,860	C. elegans SRJ-15 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002120 (Thyrotrophin-releasing hormone receptor)
28	acr-15	F25G6.4	n/a	chrV 8,554,009	A homolog of an alpha type nicotinic acetylcholine receptor subunit involved in the mediation of fast synaptic transmission at neuromuscular junctions.
29	C49C3.15	C49C3.15	n/a	chrIV 17,334,573	contains similarity to Interpro domain IPR002101 (Myristoylated alanine-rich C-kinase substrate MARCKS)
30	srt-11	W01D2.4	n/a	chrII 14,806,938	C. elegans SRT-11 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	ZK1240.1	ZK1240.1	n/a	chrII 2,330,574	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
32	K03B4.4	K03B4.4	n/a	chrV 4,684,430	contains similarity to Interpro domain IPR002411 (Cereal allergen/alpha-amylase inhibitor, rice-type)
33	des-2	T26H10.1	n/a	chrV 11,417,794	des-2 encodes an alpha subunit of nicotinic acetylcholine receptor (nAChR), predicted to be a ligand-gated ion channel regulating the fast action of acetylcholine at neuromuscular junctions and in the nervous system; DES-2 is coexpressed with and genetically interacts with DEG-3, which which it probably forms heteromultimers, and DES-2 falls into the 'DEG-3' class of nAChR subunits, probably unique to nematodes, which includes DEG-3, ACR-5, ACR-17, ACR-18 ACR-20, and ACR-23.
34	Y32B12A.1	Y32B12A.1	n/a	chrV 16,488,780	contains similarity to Pfam domain PF00569 Zinc finger, ZZ type contains similarity to Interpro domain IPR000433 (Zinc finger, ZZ-type)
35	duo-2	F29C4.5	n/a	chrIV 113,683	C. elegans DUO-2 protein; contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02338 (OTU-like cysteine protease) contains similarity to Interpro domains IPR003323 (Ovarian tumour, otubain), IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2)
36	Y43F8B.12	Y43F8B.12	n/a	chrV 19,469,274	contains similarity to Saccharomyces cerevisiae Mitotic spindle assembly; SGD:YBL063W
37	srab-12	C47A10.6	n/a	chrV 17,782,010	C. elegans SRAB-12 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
38	grl-8	ZC487.5	n/a	chrV 6,732,495	grl-8 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
39	twk-9	ZK1251.8	n/a	chrIV 9,695,064	C. elegans TWK-9 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2)
40	ZK1073.2	ZK1073.2	n/a	chrX 16,113,615	contains similarity to Aquifex aeolicus Hypothetical protein AQ_293.; SW:Y293_AQUAE
41	F14D7.5	F14D7.5	n/a	chrV 14,299,389	contains similarity to Bacteroides thetaiotaomicron Hypothetical protein.; TR:Q8ABS0
42	F41E7.7	F41E7.7	n/a	chrX 10,311,728	contains similarity to Drosophila grimshawi Chorion protein S18.; SW:CH18_DROGR
43	C55H1.1	C55H1.1	n/a	chrV 6,851,202	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
44	F25E5.4	F25E5.4	n/a	chrV 7,450,232	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
45	W02D9.10	W02D9.10	n/a	chrI 12,551,930
46	clec-201	C30H6.3	n/a	chrIV 17,359,724	C. elegans CLEC-201 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
47	R102.3	R102.3	n/a	chrIV 10,691,049	contains similarity to Broad bean wilt virus 2 210kDa protein.; TR:Q9E933
48	F37C4.8	F37C4.8	n/a	chrIV 3,880,246
49	clec-58	ZK666.3	n/a	chrII 10,475,101	C. elegans CLEC-58 protein; contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
50	T22H2.2	T22H2.2	n/a	chrI 11,705,155	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)