UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	his-56	F54E12.3	1e-41	chrIV 11,338,648	his-56 encodes an H4 histone.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
4	K08H2.2	K08H2.2	n/a	chrX 13,234,539	contains similarity to Homo sapiens Hypothetical protein KIAA0144; ENSEMBL:ENSP00000271877
5	mab-7	ZC13.4	n/a	chrX 895,155	mab-7 encodes a protein with a hydrophobic type II transmembrane region at the N-terminus, an EGF-like motif, a ShKT motif and a long C-terminus; mab-7 is involved in morphogenesis of the male tail, specifically affecting the structural cells, neuronal processes and the hypodermal sheath of the sensory rays, as such, it affects mating in males; a mab-7 promoter-gfp construct is expressed in hypodermis, body seam, ray structural cells, and several neurons in the head and tail region.
6	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
7	str-154	Y45G12C.12	n/a	chrV 2,559,268	C. elegans STR-154 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001046 (Natural resistance-associated macrophage protein), IPR000276 (GPCR, rhodopsin-like)
8	F26A1.9	F26A1.9	n/a	chrIII 4,825,812
9	ZC513.2	ZC513.2	n/a	chrV 8,055,592	contains similarity to Pfam domain PF01273 LBP / BPI / CETP family, N-terminal domain contains similarity to Interpro domain IPR001124 (Lipid-binding serum glycoprotein)
10	fzr-1	ZK1307.6	n/a	chrII 9,642,652	fzr-1 encodes a WD repeat-containing protein homologous to Cdh1/Hct1/FZR (OMIM:603619), a regulatory subunit of the anaphase-promoting complex/cyclosome (APC/C) required for anaphase initiation and exit from mitosis; FZR-1 is required for fertility, and also functions redundantly with lin-35/Rb to for normal embryogensis and control of postembryonic cell proliferation; FZR-1 probably regulates the levels of G1 cyclins, degradation of which is critical for G1 arrest.
11	K08F11.1	K08F11.1	n/a	chrIV 4,725,078
12	his-48	B0035.8	n/a	chrIV 11,324,941	his-48 encodes an H2B histone; by homology, HIS-48 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-48 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
13	C09B7.2	C09B7.2	n/a	chrX 2,669,882
14	his-59	F55G1.2	n/a	chrIV 7,488,436	his-59 encodes an H3 histone; by homology, HIS-59 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-59 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
15	K08B5.1	K08B5.1	n/a	chrX 16,560,293
16	set-16	T12D8.1	n/a	chrIII 13,650,157	C. elegans SET-16 protein ;
17	F38E11.9	F38E11.9	n/a	chrIV 9,443,446	contains similarity to Musca domestica Transposase.; TR:Q25442
18	Y38H6C.8	Y38H6C.8	n/a	chrV 20,510,594	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR002350 (Proteinase inhibitor I1, Kazal), IPR003990 (Pancreatitis-associated protein), IPR002352 (Eosinophil major basic protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
19	ttb-1	W03F9.5	n/a	chrV 160,090	C. elegans TTB-1 protein; contains similarity to Pfam domains PF00382 (Transcription factor TFIIB repeat) (2), PF08271 (TFIIB zinc-binding) contains similarity to Interpro domains IPR006670 (Cyclin), IPR000812 (Transcription factor TFIIB related), IPR011028 (Cyclin-like), IPR013763 (Cyclin-related), IPR013150 (Transcription factor TFIIB, cyclin-related), IPR013137 (Zinc finger, TFIIB-type)
20	sdz-38	ZK892.7	n/a	chrII 9,981,301	C. elegans SDZ-38 protein; contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
21	F38B2.3	F38B2.3	n/a	chrX 11,283,730	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domain IPR000859 (CUB)
22	T01D1.3	T01D1.3	n/a	chrII 175,055
23	C04G6.6	C04G6.6	n/a	chrII 5,099,576
24	srd-73	Y45G12C.7	n/a	chrV 2,528,611	C. elegans SRD-73 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
25	clec-230	C29F3.5	n/a	chrV 15,348,475	C. elegans CLEC-230 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR001202 (WW/Rsp5/WWP)
26	his-2	T10C6.13	n/a	chrV 16,041,899	his-2 encodes an H3 histone; his-2 is contained within the histone gene cluster HIS1.
27	pqn-15	C24A8.3	n/a	chrX 4,307,497	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
28	pqn-59	R119.4	n/a	chrI 377,739	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
29	ZC376.3	ZC376.3	n/a	chrV 14,169,887	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
30	F01G10.9	F01G10.9	n/a	chrIV 10,257,677	contains similarity to Interpro domain IPR000694 (Proline-rich region)
31	mtm-5	H28G03.6	n/a	chrX 5,239,010	C. elegans MTM-5 protein; contains similarity to Pfam domains PF00169 (PH domain) , PF06602 (Myotubularin-related) , PF02893 (GRAM domain) , PF02141 (DENN (AEX-3) domain) , PF03456 (uDENN domain) , PF03455 (dDENN domain) contains similarity to Interpro domains IPR005112 (dDENN), IPR010569 (Myotubularin-related), IPR001849 (Pleckstrin-like), IPR011993 (Pleckstrin homology-type), IPR005113 (uDENN), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR001194 (DENN), IPR004182 (GRAM)
32	AH9.3	AH9.3	n/a	chrX 2,259,841	contains similarity to Interpro domain IPR010916 (TonB box, conserved site)
33	Y51A2D.15	Y51A2D.15	n/a	chrV 18,602,136	contains similarity to Mus musculus Girdin (Girders of actin filament) (Coiled-coil domain-containingsprotein 88A) (Akt phosphorylation enhancer) (APE) (Hook-relatedsprotein 1) (HkRP1) (G alpha-interacting vesicle-associated protein)s(GIV).; SW:Q5SNZ0
34	C33G3.6	C33G3.6	n/a	chrX 14,082,413	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_2, whole genome shotgun sequence.; TR:A0CJH0
35	K05C4.3	K05C4.3	n/a	chrI 14,750,791	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
36	T28F2.2	T28F2.2	n/a	chrI 3,638,075	contains similarity to Homo sapiens Isoform 2 of COMM domain-containing protein 4; ENSEMBL:ENSP00000340867
37	F48B9.5	F48B9.5	n/a	chrX 2,148,428	contains similarity to Pfam domain PF00292 'Paired box' domain contains similarity to Interpro domains IPR001523 (Paired box protein, N-terminal), IPR011991 (Winged helix repressor DNA-binding), IPR009057 (Homeodomain-like)
38	Y75B8A.5	Y75B8A.5	n/a	chrIII 12,116,403	contains similarity to Interpro domain IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal)
39	F46C8.1	F46C8.1	n/a	chrX 7,550,722
40	F35G2.3	F35G2.3	n/a	chrIV 12,210,192	contains similarity to Interpro domain IPR004226 (Tubulin binding cofactor A)
41	chn-1	T09B4.10	n/a	chrI 6,182,743	chn-1 encodes an ortholog of mammalian carboxyl-terminus of Hsc70 interacting protein (CHIP), an E4 ubiquitin-chain elongation factor; chn-1 is ubiquitously expressed; chn-1(by155) mutants are viable and superficially normal, but have reduced fertility and arrest as larvae if subjected to heat shock; chn-1 overexpression causes either embryonic lethality (if strong) or defective egg-laying and locomotion, along with constitutive dauer formation (if weak); chn-1(by155) mutations suppress viable unc-45(e286ts) and unc-45(m94ts) mutations, but not lethal unc-45(st604) ones; chn-1(by155) mutants, unlike wild-type, show defective sarcomeres if overexpressing unc-45 from a extrachromosomal array; CHN-1 binds the ubiquitin conjugating enzyme UFD-2, which in turn binds the Hsp90 cochaperone UNC-45; UNC-45 is a substrate for CHN-1- and UFD-2-dependent multiubiquitination; the parkin ortholog PDR-1 binds CHN-1, and requires CHN-1 for self-ubiquitination; chn-1(RNAi) animals accumulate abnormally phosphorylated tau proteins.
42	C24H10.2	C24H10.2	n/a	chrX 5,065,438
43	F52C9.3	F52C9.3	n/a	chrIII 5,324,039	contains similarity to Pfam domain PF00781 Diacylglycerol kinase catalytic domain (presumed) contains similarity to Interpro domain IPR001206 (Diacylglycerol kinase, catalytic region)
44	dpm-3	F28D1.11	n/a	chrIV 12,391,825	dpm-3 encodes a putative regulatory subunit of dolichol phosphate mannosyltransferase, orthologous to human DPM3 (OMIM:605951); in mass RNAi assays, DPM-3 is required for normal body size, fertility, and health.
45	lnp-1	C05E11.1	n/a	chrX 4,589,579	lnp-1 encodes a highly conserved protein of unknown function, orthologous to human LUNAPARK/KIAA1715 (OMIM:610236), that is required for normally short body length, normal locomotion, fat content, acetylcholine neurotransmission, localization of RAB-3 and SNB-1, and sensitivity to aldicarb; LNP-1 is expressed in muscles, hypodermal cells, and neurons; within neurons, LNP-1 is localized to cell bodies, neuritic processes and commissures, and requiring UNC-104 for localization outside of cell bodies; LNP-1 is likely to act presynaptically; LNP-1 contains two N-terminal predicted transmembrane sequences, and an atypical zinc finger domain (C2HC2).
46	C04E12.10	C04E12.10	n/a	chrV 3,379,728	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
47	sru-42	C55A1.8	n/a	chrV 15,651,414	C. elegans SRU-42 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR002208 (SecY protein), IPR003839 (Protein of unknown function DUF215)
48	M02D8.3	M02D8.3	n/a	chrX 8,734,954	contains similarity to Dictyostelium discoideum PHD Zn finger-containing protein.; TR:Q1ZXQ2
49	his-55	F54E12.1	n/a	chrIV 11,338,029	his-55 encodes an H3 histone; by homology, HIS-55 is predicted to function as a nucleosome component required for packaging of DNA into chromatin; his-55 is a replication-dependent histone locus that resides in a histone gene-rich region on chromosome IV.
50	K10H10.4	K10H10.4	n/a	chrII 14,500,979	contains similarity to Saccharomyces cerevisiae topoisomerase I; SGD:YOL006C