UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F54D8.6	F54D8.6	0	chrIII 5,104,430	contains similarity to Interpro domain IPR000694 (Proline-rich region)
2	F25H9.1	F25H9.1	n/a	chrV 13,454,521	contains similarity to Interpro domain IPR016054 (Ly-6 antigen / uPA receptor -like)
3	F59F5.3	F59F5.3	n/a	chrX 10,539,693	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
4	T10D4.11	T10D4.11	n/a	chrII 3,149,102	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
5	C05B5.5	C05B5.5	n/a	chrIII 10,002,152	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
7	mkk-4	F42G10.2	n/a	chrX 10,028,926	mkk-4 encodes a MAP (mitogen-activated protein) kinase kinase that is a member of the MKK4 family of MAPKK's; MKK-4 activity is required in presynaptic neurons, in a dose-dependent manner, for normal presynaptic development and morphology; in regulating presynaptic organization, MKK-4 acts upstream of PMK-3/MAPK and downstream of DLK-1/MAPKKK, whose levels are negatively regulated by the RPM-1 ubiquitin ligase; a functional MKK-4::GFP fusion protein is expressed in the cytoplasm of many neurons as well as in other cell types, including the pharyngeal muscles.
8	F38A1.6	F38A1.6	n/a	chrIV 1,252,165
9	T10B5.2	T10B5.2	n/a	chrV 1,849,449
10	C32B5.13	C32B5.13	n/a	chrII 961,636	contains similarity to Pfam domain PF00112 Papain family cysteine protease contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000668 (Peptidase C1A, papain C-terminal)
11	T09E11.3	T09E11.3	n/a	chrI 12,369,888	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
12	M04C9.4	M04C9.4	n/a	chrI 9,356,115	contains similarity to Bos taurus Osteopontin precursor (Bone sialoprotein 1).; SW:OSTP_BOVIN
13	C40A11.6	C40A11.6	n/a	chrII 2,144,971	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
14	R151.1	R151.1	n/a	chrIII 7,218,656
15	srh-8	K09D9.8	n/a	chrV 4,006,527	C. elegans SRH-8 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR005394 (P2Y12 purinoceptor)
16	C39E9.7	C39E9.7	n/a	chrIV 13,074,688	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
17	VW02B12L.2	VW02B12L.2	n/a	chrII 11,439,443	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
18	Y17G7B.12	Y17G7B.12	n/a	chrII 12,024,783	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
19	srx-58	C29F3.6	n/a	chrV 15,353,194	C. elegans SRX-58 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
20	C41C4.3	C41C4.3	n/a	chrII 8,110,504	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
21	Y18D10A.9	Y18D10A.9	n/a	chrI 12,855,664	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR015943 (WD40/YVTN repeat-like)
22	nhr-226	T27B7.3	n/a	chrV 2,295,897	C. elegans NHR-226 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR000083 (Fibronectin, type I), IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	T22F3.7	T22F3.7	n/a	chrV 3,599,159	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
24	cnb-1	F55C10.1	n/a	chrV 11,376,767	cnb-1 encodes an ortholog of calcineurin B, the regulatory subunit of the protein phosphatase 2B with four EF-hand motifs for calcium binding, that binds TAX-6 (a calcineurin A ortholog) in a calcium-dependent manner; CNB-1 binds calcium, enhances the phosphatase activity of TAX-6 in vitro, promotes transcription of rcn-1, and is required for normal cuticle formation, sperm morphology, and brood size.
25	Y37A1A.3	Y37A1A.3	n/a	chrIV 13,900,330	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
26	sri-18	Y22F5A.2	n/a	chrV 10,259,578	C. elegans SRI-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	T12G3.4	T12G3.4	n/a	chrIV 12,049,069	contains similarity to Pfam domain PF03088 Strictosidine synthase contains similarity to Interpro domains IPR004141 (Strictosidine synthase), IPR011042 (Six-bladed beta-propeller, TolB-like)
28	F52H2.6	F52H2.6	n/a	chrX 2,561,931	F52H2.6 is orthologous to the human gene 3BETA-HYDROXYSTEROL DELTA 24 REDUCTASE (DHCR24; OMIM:606418), which when mutated leads to disease.
29	F52H2.1	F52H2.1	n/a	chrX 2,574,893
30	nhr-143	F59E11.11	n/a	chrV 8,974,032	C. elegans NHR-143 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
31	F33H12.1	F33H12.1	n/a	chrII 2,601,167	contains similarity to Pfam domain PF00533 BRCA1 C Terminus (BRCT) domain contains similarity to Interpro domain IPR001357 (BRCT)
32	ugt-41	F10D2.11	n/a	chrV 7,162,312	C. elegans UGT-41 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
33	ZK1248.7	ZK1248.7	n/a	chrII 5,813,080	contains similarity to Pfam domain PF02171 Piwi domain contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
34	alh-10	C54D1.4	n/a	chrX 7,142,025	C. elegans ALH-10 protein; contains similarity to Pfam domain PF00171 Aldehyde dehydrogenase family contains similarity to Interpro domains IPR016163 (Aldehyde dehydrogenase, C-terminal), IPR016162 (Aldehyde dehydrogenase, N-terminal), IPR016161 (Aldehyde/histidinol dehydrogenase), IPR015590 (Aldehyde dehydrogenase), IPR016160 (Aldehyde dehydrogenase, conserved site)
35	F54A5.2	F54A5.2	n/a	chrI 966,565	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
36	str-177	T18H9.4	n/a	chrV 9,198,343	C. elegans STR-177 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
37	C33F10.11	C33F10.11	n/a	chrII 4,834,476
38	F16G10.9	F16G10.9	n/a	chrII 2,385,448	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
39	T08D2.2	T08D2.2	n/a	chrX 167,955	contains similarity to Pfam domains PF00953 (Glycosyl transferase family 4) , PF00646 (F-box domain) contains similarity to Interpro domain IPR000715 (Glycosyl transferase, family 4)
40	F52E1.9	F52E1.9	n/a	chrV 8,398,736	contains similarity to Interpro domain IPR011332 (Ribosomal protein, zinc-binding)
41	twk-26	C33D12.3	n/a	chrX 3,052,381	C. elegans TWK-26 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
42	B0524.6	B0524.6	n/a	chrIII 1,903,905
43	F58B6.1	F58B6.1	n/a	chrIII 1,114,111	contains similarity to Pfam domain PF01764 Lipase (class 3) contains similarity to Interpro domain IPR002921 (Lipase, class 3)
44	ceh-23	ZK652.5	n/a	chrIII 7,840,469	The ceh-23 gene encodes a homeodomain protein required for a specific differentiated trait of the thermosensory interneuron AIY.
45	F22H10.5	F22H10.5	n/a	chrX 16,687,280	contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core)
46	C30G12.1	C30G12.1	n/a	chrII 7,300,470	contains similarity to Pfam domain PF06394 Pepsin inhibitor-3-like repeated domain contains similarity to Interpro domain IPR010480 (Proteinase inhibitor I33, aspin)
47	fbxa-57	C29F9.10	n/a	chrIII 106,751	C. elegans FBXA-57 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001986 (3-phosphoshikimate 1-carboxyvinyltransferase, core), IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
48	Y39A1A.20	Y39A1A.20	n/a	chrIII 10,699,807
49	rog-1	F54D12.6	n/a	chrII 1,374,343	rog-1 encodes a protein with an insulin receptor substrate-1 (IRS-type) phosphotyrosine-binding (PTB) domain that is required for the progression from pachytene to diakinesis in meiosis; rog-1 is primarily transcribed in germ cells, and this expression is required for oocyte development; ROG-1 is orthologous to human FRS2 (OMIM:607743) and FRS3 (OMIM:607744); rog-1(tm1031) mutant oocytes fail to progress from pachytene to diakinesis, a phenotype reminiscent of let-60 or mpk-1 mutant oocytes, and rog-1(tm1031) gonads lack phosphorylated MPK-1; rog-1(tm1031) and rog-1(RNAi) hermaphrodites show reduced brood sizes and increased embryonic lethality, with rog-1(tm1031) being more phenotypically severe than rog-1(RNAi); rog-1(tm1031) germ cell, brood size, and MPK-1 phosphorylation phenotypes are suppressed by the gain-of-function mutations let-60(n1046) or let-60(ga89ts); during meiosis, ROG-1 may function as an adaptor downstream of LET-23 and upstream of LET-60.
50	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)