UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F54D7.2	F54D7.2	0	chrI 4,807,641	contains similarity to Pfam domain PF01066 CDP-alcohol phosphatidyltransferase contains similarity to Interpro domains IPR014472 (Choline/ethanolaminephosphotransferase), IPR000462 (CDP-alcohol phosphatidyltransferase)
2	ZC196.5	ZC196.5	n/a	chrV 8,731,102	contains similarity to Pfam domain PF05218 Protein of unknown function (DUF713) contains similarity to Interpro domain IPR007883 (Protein of unknown function DUF713)
3	T28D6.6	T28D6.6	n/a	chrIII 11,334,762	contains similarity to Pfam domains PF01926 (GTPase of unknown function) , PF02824 (TGS domain) contains similarity to Interpro domains IPR005225 (Small GTP-binding protein), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG), IPR004095 (TGS), IPR006074 (GTP1/OBG, conserved site)
4	twk-26	C33D12.3	n/a	chrX 3,052,381	C. elegans TWK-26 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
5	gbh-1	D2089.5	n/a	chrII 10,692,053	gbh-1 encodes a predicted ortholog of human hBBOX1; expressed in the intestine and in head and body muscles.
6	F10G8.6	F10G8.6	n/a	chrI 10,047,224	F10G8.6 encodes an homolog of S. cerevisiae CFD1 (also known as YIL003W/DRE3), a putative P-loop ATPase conserved in eukaryotes and required in yeast for 4Fe-4S cluster assembly; F10G8.6 is also homologous to yeast NBP35/YGL091C; in C. elegans, F10G8.6 is required for normally rapid growth and maintenance of the germline; F10G8.6 protein was predicted to be mitochondrial on the basis of its phylogenetic profile.
7	ulp-2	Y38A8.3	n/a	chrII 4,957,746	C. elegans ULP-2 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
8	C33A12.1	C33A12.1	n/a	chrIV 9,524,313	C33A12.1 encodes the C. elegans ortholog of the NDUFA5/B13 subunit of the mitochondrial NADH dehydrogenase (ubiquinone) complex (complex I).
9	cul-6	K08E7.7	n/a	chrIV 12,588,438	cul-6 encodes a member of the cullin family that may physically interact with SKR-3.
10	K10D11.3	K10D11.3	n/a	chrIV 12,984,093	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
11	T24A6.17	T24A6.17	n/a	chrV 3,564,846
12	Y43F8C.7	Y43F8C.7	n/a	chrV 19,642,720	contains similarity to Anopheles gambiae str PEST AGAP011346-PA.; TR:Q7PST7
13	F13B6.2	F13B6.2	n/a	chrIV 7,459,793
14	elt-2	C33D3.1	n/a	chrX 10,482,266	elt-2 encodes a GATA-type transcription factor most similar to the vertebrate GATA4-6 transcription factors required for cardiac and endoderm development (OMIM:601656, 600576); in C. elegans, ELT-2 is required redundantly with ELT-7 for initiating and maintaining terminal differentiation of the intestine; ELT-2 is expressed solely in the intestine, beginning embryonically at the 2E-cell stage and continuing in all intestinal cells throughout the life of the animal; in the regulatory hierarchy controlling endoderm development, ELT-2 lies downstream of the maternal regulators SKN-1 and POP-1 and the embryonic GATA factors MED-1/-2, and END-1/-3; in turn, ELT-2, along with ELT-7, likely regulates transcription of a number of intestine-specific terminal differentiation genes such as ges-1, ifb-2, pha-4, and the stress-induced mtl-2; ELT-2 also positively autoregulates, presumably to ensure maintenance of intestinal differentiation
15	F16G10.9	F16G10.9	n/a	chrII 2,385,448	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
16	K02G10.5	K02G10.5	n/a	chrX 4,689,524	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF03137 (Organic Anion Transporter Polypeptide (OATP) family) contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
17	rad-26	C27B7.4	n/a	chrIV 8,897,727	C. elegans RAD-26 protein; contains similarity to Pfam domains PF00271 (Helicase conserved C-terminal domain) , PF00176 (SNF2 family N-terminal domain) contains similarity to Interpro domains IPR000330 (SNF2-related), IPR000694 (Proline-rich region), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal), IPR000276 (GPCR, rhodopsin-like)
18	F13E6.2	F13E6.2	n/a	chrX 10,671,215	contains similarity to Pfam domain PF05186 Dpy-30 motif contains similarity to Interpro domains IPR000850 (Adenylate kinase), IPR007858 (Dpy-30), IPR011769 (Adenylate/cytidine kinase, N-terminal)
19	C11D2.3	C11D2.3	n/a	chrIV 6,154,348
20	F55G1.9	F55G1.9	n/a	chrIV 7,476,741	contains similarity to Pfam domain PF03807 NADP oxidoreductase coenzyme F420-dependent contains similarity to Interpro domains IPR004455 (NADP oxidoreductase, coenzyme F420-dependent), IPR000304 (Delta 1-pyrroline-5-carboxylate reductase), IPR016040 (NAD(P)-binding)
21	dnc-2	C28H8.12	n/a	chrIII 5,925,025	dnc-2 encodes a member of the dynamitin family that affects spindle alignment in polarized cells in early embryos, nuclear movement, spindle morphology, chromosome segregation, and pronuclear migration.
22	C08B6.8	C08B6.8	n/a	chrV 10,138,746	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
23	C50D2.8	C50D2.8	n/a	chrII 97,034	contains similarity to Pfam domain PF03194 LUC7 N_terminus contains similarity to Interpro domain IPR004882 (LUC7 related)
24	T22F3.7	T22F3.7	n/a	chrV 3,599,159	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
25	Y40B1B.8	Y40B1B.8	n/a	chrI 13,431,748	contains similarity to Pfam domain PF00153 Mitochondrial carrier protein contains similarity to Interpro domain IPR001993 (Mitochondrial substrate carrier)
26	cnb-1	F55C10.1	n/a	chrV 11,376,767	cnb-1 encodes an ortholog of calcineurin B, the regulatory subunit of the protein phosphatase 2B with four EF-hand motifs for calcium binding, that binds TAX-6 (a calcineurin A ortholog) in a calcium-dependent manner; CNB-1 binds calcium, enhances the phosphatase activity of TAX-6 in vitro, promotes transcription of rcn-1, and is required for normal cuticle formation, sperm morphology, and brood size.
27	cup-4	C02C2.3	n/a	chrIII 7,867,528	The primary phenotype of cup-4 animals is an accumulation of secreted GFP in the pseudocoelom, suggesting a decrease in, or the absence of, endocytosis in coelomocytes.
28	gfi-3	M163.4	n/a	chrX 14,482,535	gfi-3 is also known as apc-5, encoding a distant homolog of the human anaphase promoting complex subunit APC5, but is most closely related to its C. elegans paralog Y66D12A.17; gfi-3(RNAi) animals are generally unable to progress through meiotic divisions; initially they produce reduced numbers of viable embryos mixed with inviable embryos, but then show severe germline maintenance defects and become sterile.
29	C09F9.2	C09F9.2	n/a	chrII 14,708,961	contains similarity to Pfam domains PF01390 (SEA domain) , PF01826 (Trypsin Inhibitor like cysteine rich domain) (3), PF07974 (EGF-like domain) , PF03351 (DOMON domain) (4)contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006210 (EGF), IPR005018 (DOMON related), IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR000082 (SEA), IPR008960 (Carbohydrate-binding family 9/cellobiose dehydrogenase, cytochrome), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular), IPR013050 (DOMON)
30	R12C12.5	R12C12.5	n/a	chrII 6,044,615	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
31	C32D5.10	C32D5.10	n/a	chrII 6,350,550	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
32	K08D10.5	K08D10.5	n/a	chrIV 4,168,957	contains similarity to Rhodopirellula baltica DNA-binding protein SMUBP-2.; TR:Q7UWP1
33	gip-2	C45G3.3	n/a	chrI 9,227,490	gip-2 encodes a member of the Biotin/lipoate A/B protein ligase family.
34	H28O16.2	H28O16.2	n/a	chrI 12,649,720	contains similarity to Pfam domain PF00498 FHA domain contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR000253 (Forkhead-associated)
35	srx-108	F40H7.2	n/a	chrII 3,706,336	C. elegans SRX-108 protein ;
36	B0495.9	B0495.9	n/a	chrII 7,708,071
37	glt-6	R05G6.6	n/a	chrIV 7,505,011	glt-6 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
38	ckb-4	F22F7.5	n/a	chrV 2,107,900	ckb-4 encodes an isoform of choline kinase whose activity has been verified in vitro, and that has a strong preference for choline over ethanolamine; CKB-1 through CKB-4 comprise a related group ('B') of choline kinases.
39	nhx-1	B0395.1	n/a	chrX 16,020,136	nhx-1 encodes a sodium/proton exchanger expressed intracellularly within hypodermal and muscle cells; NHX-1 is required for embryonic viability, and is thought to prevent intracellular acidification by catalysing the electroneutral exchange of vesicular sodium for an intracellular proton.
40	F28C6.8	F28C6.8	n/a	chrII 8,607,222	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
41	rha-1	T07D4.3	n/a	chrII 8,880,999	rha-1 encodes an ATP-dependent DEAD/H box RNA helicase orthologous to human RNA helicase A and Drosophila Maleless, an essential component of the dosage compensation machinery required for increased X-linked transcription in males; by homology, RHA-1 is predicted to function in regulation of transcription, translation, RNA processing, and/or RNA replication; in C. elegans, RHA-1 is required for germ cell proliferation, normal germ cell nuclear morphology, RNA-mediated interference (RNAi) of germline-expressed genes, and silencing of germline-expressed transgenes; RHA-1 is reported to localize to the nucleus and the cytoplasm.
42	dnc-1	ZK593.5	n/a	chrIV 10,929,896	DNC-1 encodes a dynactin, orthologous to Drosophila GLUED, that is required for pronuclear migration and centrosome separation in one-cell embryos and for the correct alignment of mitotic spindles in early embryos; DNC-1 shares embryonic functions with DNC-2, DHC-1, LIS-1 and NUD-1; DNC-1 is located at cortical microtubule attachment sites.
43	srt-69	B0238.8	n/a	chrV 5,264,800	C. elegans SRT-69 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
44	smg-5	W02D3.8	n/a	chrI 6,735,096	smg-5 encodes a novel protein that contains two N-terminal tetratricopeptide (TPR) repeats and a C-terminal PINc domain found in nucleotide-binding proteins; SMG-5 is a component of the nonsense-mediated mRNA decay (NMD) pathway and likely functions in regulation of dephosphorylation of SMG-2, the C. elegans UPF1 ortholog, an ATPase and RNA helicase required for NMD in worms, yeast, and mammals; SMG-5 physically interacts with SMG-7, SMG-2, and the PAA-1 and LET-92 structural and catalytic subunits, respectively, of a protein phosphatase 2A (PP2A), suggesting that SMG-5 may function to direct SMG-2 to a PP2A phosphatase that regulates its activity in vivo; SMG-5 also interacts, in vivo, with components of the RNA interference (RNAi) pathway, suggesting a potential link between RNAi and NMD; SMG-5::GFP fusion proteins localize to both the nucleus and the cytoplasm.
45	C46G7.2	C46G7.2	n/a	chrIV 6,016,483	contains similarity to Anisakis simplex 29kDa protein from Anisakis simplex.; TR:Q9U5Z9
46	W06A11.4	W06A11.4	n/a	chrII 4,056,790
47	str-255	C45H4.15	n/a	chrV 2,162,667	C. elegans STR-255 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000301 (CD9/CD37/CD63 antigen)
48	C52G5.2	C52G5.2	n/a	chrX 12,844,270	contains similarity to Pfam domain PF08768 Domain of unknown function (DUF1794) contains similarity to Interpro domain IPR014878 (Region of unknown function DUF1794)
49	F56D1.2	F56D1.2	n/a	chrII 5,476,416	contains similarity to Pfam domain PF08357 SEFIR domain contains similarity to Interpro domain IPR013568 (SEFIR)
50	T09E8.3	T09E8.3	n/a	chrV 13,180,913	contains similarity to Pfam domain PF03311 Cornichon protein contains similarity to Interpro domain IPR003377 (Cornichon)