UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	emb-30	F54C8.3	0	chrIII 9,438,172	emb-30 encodes an anaphase-promoting complex/cyclosome (APC/C) component orthologous to mammalian APC-4 and Schizosaccharomyces pombe Lid1; EMB-30 is required for the metaphase-to-anaphase transition during meiosis and mitosis, for establishing anterior-posterior polarity in the early embryo, and for proper localization of germline granules and the maternally provided PAR-2 and PAR-3 proteins.
2	H37A05.2	H37A05.2	n/a	chrV 13,632,011	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
3	tag-322	C33H5.10	n/a	chrIV 7,784,751	C. elegans TAG-322 protein ; contains similarity to Drosophila melanogaster Flybase gene name is CG5913-PA;; FLYBASE:CG5913
4	srx-38	C03A7.5	n/a	chrV 5,154,771	C. elegans SRX-38 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
5	F41G4.5	F41G4.5	n/a	chrX 16,831,782
6	glr-8	F22A3.3	n/a	chrX 6,508,340	glr-8 encodes a highly divergent putative ionotropic glutamate receptor subunit, unclassifiable as NMDA or non-NMDA (though possibly of the Delta subfamily), and without any clear close homologs in metazoa or plants; glr-8 is expressed in the pharyngeal nervous system, the body wall mechanoreceptors ALM and PLM, and two other neurons (BDU and URB); glr-8 is expressed from embryogenesis to adulthood.
7	B0432.9	B0432.9	n/a	chrII 283,160	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
8	srh-17	C47E8.2	n/a	chrV 14,662,094	C. elegans SRH-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	T26A5.6	T26A5.6	n/a	chrIII 6,449,449	contains similarity to Interpro domain IPR001194 (DENN)
10	sru-2	C33A12.13	n/a	chrIV 9,486,898	C. elegans SRU-2 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
11	W06B4.3	W06B4.3	n/a	chrII 4,464,653	contains similarity to Pfam domain PF05131 Pep3/Vps18/deep orange family contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR007810 (Pep3/Vps18/deep orange), IPR016024 (Armadillo-type fold)
12	T12E12.3	T12E12.3	n/a	chrIV 5,543,170
13	srd-50	F15A2.4	n/a	chrX 13,480,135	C. elegans SRD-50 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	R09A8.1	R09A8.1	n/a	chrX 12,615,226	contains similarity to Homo sapiens FLASH; ENSEMBL:ENSP00000237177
15	str-187	F26D10.8	n/a	chrIV 17,266,207	C. elegans STR-187 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000539 (Frizzled protein)
16	F54D12.1	F54D12.1	n/a	chrII 1,400,894	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
17	F12A10.1	F12A10.1	n/a	chrII 5,497,839	contains similarity to Oryza sativa subsp indica Putative uncharacterized protein.; TR:A2YC95
18	srh-211	D1065.5	n/a	chrV 4,078,922	C. elegans SRH-211 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
19	T01D3.2	T01D3.2	n/a	chrV 13,706,650	contains similarity to Pfam domain PF00989 PAS fold contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR013767 (PAS fold), IPR000014 (PAS), IPR011598 (Helix-loop-helix DNA-binding), IPR001067 (Nuclear translocator)
20	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
21	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
22	ddl-2	Y48E1B.1	n/a	chrII 13,545,140	C. elegans DDL-2 protein; contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000381 (Inhibin, beta B subunit), IPR000694 (Proline-rich region), IPR003882 (Pistil-specific extensin-like protein)
23	wrm-1	B0336.1	n/a	chrIII 5,724,932	wrm-1 encodes, along with bar-1 and hmp-2, one of three C. elegans beta-catenin-like proteins; during development, wrm-1 functions in noncanonical Wnt signaling pathways that specify cell fates in the early embryo, the somatic gonad, and postembryonic hypodermal lineages.
24	T08A9.6	T08A9.6	n/a	chrX 7,312,318	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
25	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
26	dhs-19	T11F9.11	n/a	chrV 11,489,664	dhs-19 encodes a short-chain dehydrogenase predicted to be mitochondrial.
27	B0212.3	B0212.3	n/a	chrIV 3,541,891	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR001202 (WW/Rsp5/WWP)
28	B0035.16	B0035.16	n/a	chrIV 11,295,988	contains similarity to Pfam domain PF03054 tRNA methyl transferase contains similarity to Interpro domains IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004506 (tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase)
29	fbxa-22	T12B5.5	n/a	chrIII 939,140	C. elegans FBXA-22 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
30	C26B2.7	C26B2.7	n/a	chrIV 8,016,527
31	W06D11.4	W06D11.4	n/a	chrX 12,302,364	contains similarity to Pfam domain PF08123 Histone methylation protein DOT1 contains similarity to Interpro domain IPR013110 (Histone methylation DOT1)
32	C27D8.4	C27D8.4	n/a	chrIV 12,705,410	contains similarity to Interpro domains IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
33	rap-1	C27B7.8	n/a	chrIV 8,917,869	rap-1 encodes a member of the Ras superfamily of small GTPases; the activated protein interacts with W05B10.4 and T14G10.2 in yeast two-hybrid assays and rap-1 is expressed in some neurons in the head and tail, the rectal epithelial cells, body muscle, hypodermis, and in the somatic cells of the gonad.
34	F45G2.9	F45G2.9	n/a	chrIII 13,436,244	contains similarity to Pfam domain PF01728 FtsJ-like methyltransferase contains similarity to Interpro domains IPR016448 (23S ribosomal RNA methyltransferase), IPR015507 (Ribosomal RNA methyltransferase J), IPR002877 (Ribosomal RNA methyltransferase RrmJ/FtsJ)
35	nhr-177	F16B4.1	n/a	chrV 1,611,519	C. elegans NHR-177 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
36	C25F6.6	C25F6.6	n/a	chrX 5,450,509
37	str-193	C50C10.6	n/a	chrV 9,821,161	C. elegans STR-193 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	F56G4.6	F56G4.6	n/a	chrI 11,369,184	contains similarity to Interpro domain IPR001623 (Heat shock protein DnaJ, N-terminal)
39	F58B3.7	F58B3.7	n/a	chrIV 11,639,167	contains similarity to Pfam domains PF01585 (G-patch domain) , PF00076 (RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR016967 (Splicing factor, SPF45), IPR003954 (RNA recognition, region 1), IPR000467 (D111/G-patch), IPR000504 (RNA recognition motif, RNP-1), IPR009145 (U2 auxiliary factor small subunit)
40	T03G11.4	T03G11.4	n/a	chrX 5,167,050	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domain IPR001382 (Glycoside hydrolase, family 47)
41	sra-31	C56C10.5	n/a	chrII 6,577,792	C. elegans SRA-31 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
42	C14A4.11	C14A4.11	n/a	chrII 10,606,420	contains similarity to Pfam domain PF06840 Protein of unknown function (DUF1241) contains similarity to Interpro domain IPR009652 (Protein of unknown function DUF1241)
43	srbc-17	C45H4.3	n/a	chrV 2,178,415	C. elegans SRBC-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
44	ape-1	F46F3.4	n/a	chrV 11,680,585	ape-1 encodes an ortholog of inhibitory p53-interacting protein (iASPP); APE-1 binds CEP-1 in vitro, and shares 38% amino-acid identity in its ankyrin repeats and SH3 domain to iASPP, with many iASPP residues contacting p53 being conserved; RNAi of ape-1 induces CEP-1- and HUS-1-dependent apoptosis in the germline, consistent with inhibition of the CEP-1/HUS-1 DNA damage checkpoint by APE-1 in the germline; excess ape-1(RNAi) apoptosis also requires CED-3.
45	C36B7.4	C36B7.4	n/a	chrX 7,086,834
46	atg-16.1	F02E8.5	n/a	chrX 4,461,104	atg-16.1 encodes a divergent ortholog of the autophagic budding yeast protein Atg16p, and of human ATG16L1 (OMIM:610767, associated with Crohn disease) and ATG16L2; ATG-16.1 is paralogous to ATG-16.2; ATG-16.1 is expressed in larval and adult intestine, renal gland cells, stomato-intestinal muscle, anal depressor muscle, and head mesodermal cell; ATG-16.1 has no obvious function in mass RNAi assays.
47	K07D4.2	K07D4.2	n/a	chrII 4,045,127
48	R151.8	R151.8	n/a	chrIII 7,228,224	contains similarity to Interpro domains IPR001005 (SANT, DNA-binding), IPR009057 (Homeodomain-like)
49	F54D11.3	F54D11.3	n/a	chrV 4,636,257
50	adr-2	T20H4.4	n/a	chrIII 7,231,956	adr-2 encodes an adenosine deaminase that acts on RNA (ADAR); ADARs are RNA-editing enzymes that deaminate adenosines to create inosines in double-stranded RNA (dsRNA); adr-2 is expressed ubiquitously in early embryos, as well as in the germline of early adults; ADR-2 is required for ADAR activity in vivo, and for normal chemotaxis.