UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F53C3.4	F53C3.4	2e-118	chrII 3,902,067	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
2	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
3	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
4	F53C3.3	F53C3.3	2.0000000000000002e-66	chrII 3,903,698	contains similarity to Pfam domain PF01705 CX module contains similarity to Interpro domain IPR002619 (Protein of unknown function CX)
5	T10C6.2	T10C6.2	n/a	chrV 16,013,354	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	T10B5.4	T10B5.4	n/a	chrV 1,871,195	contains similarity to Pfam domain PF00583 Acetyltransferase (GNAT) family contains similarity to Interpro domains IPR000182 (GCN5-related N-acetyltransferase), IPR016181 (Acyl-CoA N-acyltransferase)
7	C55A1.4	C55A1.4	n/a	chrV 15,642,939	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
8	pin-2	F07C6.1	n/a	chrIV 12,794,963	pin-2 encodes a LIM domain-containing protein that, along with UNC-97, comprises the two C. elegans members of the PINCH family of predicted adapter proteins; based upon its similarity to Drosophila and vertebrate members of the PINCH family, PIN-2 is predicted to play a role in regulation of cell morphology, motility, and survival, but as loss of pin-2 via large-scale RNAi results in no obvious defects, the precise role of PIN-2 in C. elegans development and/or behavior is not yet known; a PIN-2::GFP fusion protein is first expressed in embryos just prior to hatching and in early larvae is seen in several neurons, including the PVT neuron, and in intestinal cells; during postembryonic development, neuronal expression continues, whereas intestinal expression gradually declines; PIN-2 localizes to the cytoplasm and to the nucleus, and in neurons, is seen in axonal processes and varicosities.
9	fkh-8	F40H3.4	n/a	chrII 6,190,440	fkh-8 encodes one of 15 C. elegans forkhead transcription factors; loss of fkh-8 activity via RNAi has been reported to result in either no defects or a weakly penetrant aldicarb resistance phenotype; an FKH-8 reporter fusion is expressed in nerve cells in the head and tail ganglia of both males and hermaphrodites with expression beginning in the later stages of embryogenesis and continuing through adulthood.
10	unc-42	F58E6.10	n/a	chrV 9,766,975	unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
11	F10E9.1	F10E9.1	n/a	chrIII 8,323,702
12	F41C3.6	F41C3.6	n/a	chrII 4,735,969
13	F40G9.6	F40G9.6	n/a	chrIII 179,840
14	ZC168.2	ZC168.2	n/a	chrIV 10,728,759	contains similarity to Pfam domain PF01147 Crustacean CHH/MIH/GIH neurohormone family contains similarity to Interpro domain IPR001166 (Crustacean neurohormone)
15	K10G6.4	K10G6.4	n/a	chrII 3,973,888	contains similarity to Interpro domain IPR000533 (Tropomyosin)
16	E03H4.7	E03H4.7	n/a	chrI 12,422,814	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
17	H37N21.1	H37N21.1	n/a	chrI 7,143,753	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001397 (5-Hydroxytryptamine 5A receptor), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
18	C33E10.1	C33E10.1	n/a	chrX 17,305,742	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
19	W04G5.7	W04G5.7	n/a	chrI 11,653,511	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
20	gpa-9	F56H9.4	n/a	chrV 12,648,055	gpa-9 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASJ, PHB, PVQ, pharyngeal muscle, and the spermatheca.
21	F08D12.13	F08D12.13	n/a	chrII 2,795,880
22	W05B10.4	W05B10.4	n/a	chrV 12,668,893	contains similarity to Pfam domain PF00788 Ras association (RalGDS/AF-6) domain contains similarity to Interpro domain IPR000159 (Ras-association)
23	C35E7.3	C35E7.3	n/a	chrI 10,837,920
24	srw-57	F36G9.1	n/a	chrV 15,954,286	C. elegans SRW-57 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000276 (GPCR, rhodopsin-like)
25	srh-140	Y6E2A.6	n/a	chrV 15,723,067	C. elegans SRH-140 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000484 (Photosynthetic reaction centre, L and M subunits)
26	osm-1	T27B1.1	n/a	chrX 16,546,188	osm-1 encodes a WD- and WAA-repeat containing protein that is the C. elegans ortholog of intraflagellar transport (IFT) complex B component IFT172; OSM-1 is a presumptive cargo molecule for kinesin-II, and OSM-1 is required, along with OSM-6, for the proper assembly of the middle segments of sensory cilia; osm-1 may act in a pathway with avr-14 to affect resistance to ivermectin-induced cessation of pumping, and mutants are defective in avoidance of solutions of high osmotic strength; an OSM-1::GFP fusion protein is expressed in amphid and phasmid chemosensory neurons where it undergoes both anterograde and retrograde intraflagellar transport.
27	ZK938.2	ZK938.2	n/a	chrII 9,837,617	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
28	pmk-1	B0218.3	n/a	chrIV 8,149,748	pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway.
29	srbc-50	F54B8.8	n/a	chrV 15,824,406	C. elegans SRBC-50 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
30	nhr-115	T27B7.4	n/a	chrV 2,293,666	nhr-115 encodes a nuclear receptor that is most highly conserved amongst nematode species.
31	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
32	dyf-11	C02H7.1	n/a	chrX 765,241	dyf-11 encodes a conserved protein orthologous to the human microtubule-binding protein MIP-T3 and that contains a lysine-rich region and a C-terminal coiled-coil domain present in a number of intraflagellar transport (IFT) complex B proteins; DYF-11 activity is required continuously in sensory neurons for formation of medial and distal ciliary segments and thus, for normal sensory cilium morphology and function and chemotaxis; a dyf-11::gfp promoter fusion is expressed in all ciliated sensory neurons as well as in the AQR, PQR, ADE, and PDR neurons; a DYF-11::GFP protein fusion is detected throughout the cilium and appears to localize to IFT-B particles in a manner consistent with an early role in IFT-B particle assembly; dyf-11 expression in ciliated neurons is dependent upon the presence of the DAF-19 RFX transcription factor.
33	T20F7.6	T20F7.6	n/a	chrX 16,867,473	contains similarity to Pfam domain PF00571 CBS domain pair contains similarity to Interpro domain IPR000644 (Cystathionine beta-synthase, core)
34	cyp-33C1	C45H4.2	n/a	chrV 2,180,672	C. elegans CYP-33C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
35	hlh-26	C17C3.8	n/a	chrII 5,533,262	C. elegans HLH-26 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
36	F20C5.6	F20C5.6	n/a	chrIV 8,772,362	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DLG0
37	F42A9.9	F42A9.9	n/a	chrIV 8,638,434
38	inx-6	C36H8.2	n/a	chrIV 12,748,113	inx-6 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; INX-6 is required for formation of pharyngeal gap junctions and thus for the electrical coupling and synchronous muscle contractions necessary for normal feeding behavior and postembryonic development; INX-6 may function redundantly with EAT-5, another C. elegans innexin; INX-6 expression is first detected in embryonic pharyngeal precursors and during later larval and adult stages, in pharyngeal corpus muscles and isthmus marginal cells, where INX-6 localizes to plaque-like structures in the plasma membrane.
39	srh-39	C06A8.7	n/a	chrII 7,764,656	C. elegans SRH-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	fmo-2	K08C7.5	n/a	chrIV 10,683,426	fmo-2 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria).
41	F58G1.7	F58G1.7	n/a	chrII 12,945,904	contains similarity to Interpro domain IPR008075 (Lipocalin-1 receptor)
42	E03H4.3	E03H4.3	n/a	chrI 12,406,224	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
43	glb-27	W01C9.5	n/a	chrII 8,548,030	glb-27 encodes a globin whose expression is probably induced by anoxia in a HIF-1-dependent manner; glb-27 transcription is higher in L3 and dauers than in young adults; glb-27 has no obvious function in mass RNAi assays.
44	C04A11.2	C04A11.2	n/a	chrX 13,667,311	contains similarity to Homo sapiens Putative protein TPRXL; ENSEMBL:ENSP00000322097
45	fbxa-103	F09C3.4	n/a	chrI 14,288,863	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
46	srg-68	ZC317.5	n/a	chrV 5,464,597	C. elegans SRG-68 protein ;
47	C35A11.1	C35A11.1	n/a	chrV 5,406,834	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
48	R08C7.1	R08C7.1	n/a	chrIV 4,451,940
49	K06A1.1	K06A1.1	n/a	chrII 6,455,658	K06A1.1 encodes an AP-2-like transcription factor.
50	srg-41	T19C4.3	n/a	chrV 11,161,148	C. elegans SRG-41 protein; contains similarity to Interpro domains IPR000500 (Connexins), IPR000609 (Serpentine gamma receptor, Caenorhabditis species)