UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F53B7.4	F53B7.4	0	chrV 11,001,724	contains similarity to Interpro domains IPR004090 (Chemotaxis methyl-accepting receptor), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich)
2	mdt-22	ZK970.3	n/a	chrII 10,301,446	C. elegans MDT-22 protein; contains similarity to Pfam domain PF06179 Surfeit locus protein 5 contains similarity to Interpro domain IPR009332 (Surfeit locus 5)
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	nhr-192	F57A8.5	n/a	chrV 10,069,976	C. elegans NHR-192 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
5	F47B7.3	F47B7.3	n/a	chrX 3,763,711	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
6	F35E8.10	F35E8.10	n/a	chrV 15,919,877	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
7	F35G12.7	F35G12.7	n/a	chrIII 4,586,958	contains similarity to Pfam domain PF03091 CutA1 divalent ion tolerance protein contains similarity to Interpro domains IPR004323 (Divalent ion tolerance protein, CutA1), IPR011322 (Nitrogen regulatory PII-like, alpha/beta)
8	srg-16	F15A4.4	n/a	chrII 12,468,465	C. elegans SRG-16 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
9	W02D7.5	W02D7.5	n/a	chrV 8,298,506	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
10	srx-48	T26H8.2	n/a	chrV 15,303,024	C. elegans SRX-48 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
11	F20B6.7	F20B6.7	n/a	chrX 4,207,129
12	T01C3.1	T01C3.1	n/a	chrV 14,989,266	contains similarity to Pfam domains PF00169 (PH domain) , PF06920 (Dedicator of cytokinesis) contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR000694 (Proline-rich region), IPR010703 (Dedicator of cytokinesis)
13	F18E9.1	F18E9.1	n/a	chrX 8,601,003
14	gur-5	ZK622.2	n/a	chrII 5,287,091	C. elegans GUR-5 protein ;
15	grd-7	F46H5.6	n/a	chrX 7,269,472	grd-7 encodes a hedgehog-like protein, with an N-terminal DUF271 domain, a central low-complexity proline-rich domain, and a C-terminal Ground (Grd) domain; GRD-7 is expressed in three to four posterior DA motor neurons of the ventral nerve cord; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-7 is weakly required for normal molting; GRD-7 is also required for normal growth to full size, cuticle adhesion, locomotion, and vulval morphogenesis; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
16	srab-20	T20D4.1	n/a	chrV 3,429,701	C. elegans SRAB-20 protein; contains similarity to Interpro domain IPR002184 (Serpentine beta receptor)
17	M01E11.1	M01E11.1	n/a	chrI 5,582,772	contains similarity to Pfam domain PF04140 Isoprenylcysteine carboxyl methyltransferase (ICMT) family contains similarity to Interpro domain IPR007269 (Isoprenylcysteine carboxyl methyltransferase)
18	C30G12.3	C30G12.3	n/a	chrII 7,275,917
19	B0454.8	B0454.8	n/a	chrII 3,042,189	contains similarity to Pfam domain PF02795 Domain of unknown function (DUF225) contains similarity to Interpro domain IPR004024 (Protein of unknown function DUF225)
20	srg-9	T12A2.10	n/a	chrIII 6,256,061	C. elegans SRG-9 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
21	2L52.1	2L52.1	n/a	chrII 3,265	2L52.1 encodes a protein with sequence similarity to GLI-family zinc-finger transcription factors; deletion mutations in 2L52.1 are reported to be homozygous viable.
22	gcy-13	F23H12.6	n/a	chrV 12,366,622	gcy-13 encodes a predicted guanylate cyclase.
23	W05H5.3	W05H5.3	n/a	chrII 12,446,465	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domain IPR001204 (Phosphate transporter)
24	F22H10.1	F22H10.1	n/a	chrX 16,702,858	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
25	W04G5.4	W04G5.4	n/a	chrI 11,631,445	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domains IPR008996 (Cytokine, IL-1-like), IPR006588 (Protein of unknown function PAW)
26	sdz-20	F53A2.2	n/a	chrIII 13,335,391	C. elegans SDZ-20 protein
27	gcy-17	W03F11.2	n/a	chrI 2,228,250	gcy-17 encodes a predicted guanylate cyclase.
28	mnm-2	C10A4.8	n/a	chrX 7,423,795	C. elegans MNM-2 protein; contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007086 (Zinc finger, C2H2-subtype), IPR013087 (Zinc finger, C2H2-type/integrase, DNA-binding), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
29	M151.3	M151.3	n/a	chrII 3,629,023	contains similarity to Homo sapiens Isoform 2 of Girdin; ENSEMBL:ENSP00000263630
30	fbxb-106	F29A7.1	n/a	chrII 2,763,216	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
31	pqn-11	C09G1.1	n/a	chrX 15,969,125	PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.
32	C24H10.1	C24H10.1	n/a	chrX 5,073,103	C24H10.1 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; C24H10.1 is worm-specific, with obvious homologs only in C. elegans; C24H10.1 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
33	T05H4.7	T05H4.7	n/a	chrV 6,416,194	contains similarity to Pfam domain PF00182 Chitinase class I contains similarity to Interpro domain IPR000726 (Glycoside hydrolase, family 19, catalytic)
34	T25G12.2	T25G12.2	n/a	chrX 17,245,951	The T25G12.2 gene encodes a homolog of the human gene HSD, which when mutated leads to cortisol 11-beta ketoreductase deficiency (OMIM:218030); T25G12.2 protein is predicted to be mitochondrial with 68% accuracy.
35	C01F6.1	C01F6.1	n/a	chrIV 9,098,665	C01F6.1 encodes a putative calcium-dependent phospholipid binding protein of the copine family; C01F6.1 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; C01F6.1(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
36	M110.3	M110.3	n/a	chrII 8,215,496	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
37	K08F9.1	K08F9.1	n/a	chrV 15,138,399	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
38	Y106G6H.16	Y106G6H.16	n/a	chrI 10,475,167	contains similarity to Salmonella typhimurium Putative cytoplasmic protein (STMF1.42 protein).; TR:Q9L9K2
39	F27C8.3	F27C8.3	n/a	chrIV 9,595,409	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ICY1
40	R01B10.2	R01B10.2	n/a	chrV 6,042,173
41	K08E4.3	K08E4.3	n/a	chrIV 12,058,560	contains similarity to Phytolacca americana Mitogen PL-B.; TR:Q9AVB0
42	acr-9	C40C9.2	n/a	chrX 13,644,544	acr-9 encodes a predicted member of the alpha subunit family of nicotinic acetylcholine receptors.
43	ZK1240.4	ZK1240.4	n/a	chrII 2,315,354
44	F14B8.2	F14B8.2	n/a	chrX 6,904,852
45	str-229	C17E7.11	n/a	chrV 3,901,512	C. elegans STR-229 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	srbc-32	C02A12.5	n/a	chrV 3,486,251	C. elegans SRBC-32 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
47	set-9	F15E6.1	n/a	chrIV 4,312,255	set-9 encodes a large (1,655-residue) protein with a low-complexity N-terminal region, followed by a PHD-zinc finger and a SET domain; SET-9 has no non-nematode orthologs, but has 96% identity (1616/1679 residues) to its paralog SET-26; SET-9 is required for a normally short lifespan and low spontaneous mutation rate; life extension by set-9(RNAi) requires DAF-16, indicating that SET-9 limits normal lifespan by negatively regulating DAF-16 (either directly or indirectly); otherwise, neither set-9(n4949) nor set-9(RNAi) have any obvious phenotypes.
48	gmd-2	F56H6.5	n/a	chrI 12,293,092	gmd-2 encodes one of two C. elegans GDP-mannose dehydratases; in vitro, and when coexpressed with GER-1, GMD-2 catalyzes the formation of GDP-fucose from GDP-mannose; gmd-2 transcripts are generally present throughout larval and adult stages.
49	srw-55	T05G11.6	n/a	chrV 15,939,538	C. elegans SRW-55 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300)
50	fbxb-67	F49B2.2	n/a	chrI 14,297,764	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.