UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F52H3.5	F52H3.5	3e-98	chrII 10,030,510	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) , PF00515 (Tetratricopeptide repeat) (3)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
2	scl-27	ZK6.3	n/a	chrV 400,930	C. elegans SCL-27 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
3	C09B8.4	C09B8.4	n/a	chrX 6,019,168	contains similarity to Pfam domain PF05705 Eukaryotic protein of unknown function (DUF829) contains similarity to Interpro domain IPR008547 (Protein of unknown function DUF829, eukaryotic)
4	aco-1	ZK455.1	n/a	chrX 11,341,447	aco-1 encodes an aconitase that is homologous to mammalian iron regulatory protein-1 (IRP1); aco-1 activity is required for normal brood sizes and, under iron stress conditions, for normal lifespan and L4-to-adult growth rates; ACO-1 physically interacts with GEX-3; like IRP1, ACO-1 has aconitase activity and is post-translationally regulated by iron, but, unlike IRP1, it lacks RNA-binding activity; ACO-1 is predicted to be mitochondrial, and its mRNA levels appear to decrease in response to iron treatment.
5	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
6	sulp-1	C55B7.6	n/a	chrI 6,484,156	sulp-1 encodes one of eight C. elegans members of the sulfate permease family of anion transporters; by homology, SULP-1 is predicted to function as an anion transporter that regulates cellular pH and volume via transmembrane movement of electrolytes and fluids; a sulp-1::GFP transcriptional fusion is expressed strongly in several neurons, weakly in hypodermal cells and the intestine, and very faintly in the excretory cell and body wall muscle.
7	col-63	ZK265.2	n/a	chrI 8,244,320	C. elegans COL-63 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR000694 (Proline-rich region), IPR008160 (Collagen triple helix repeat)
8	str-56	T06C12.3	n/a	chrV 15,873,145	C. elegans STR-56 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003569 (Cytochrome c-type biogenesis protein CcbS)
9	F54D10.8	F54D10.8	n/a	chrII 3,826,789	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
10	srz-54	Y102A5C.25	n/a	chrV 16,981,243	C. elegans SRZ-54 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
11	C01G12.7	C01G12.7	n/a	chrII 14,590,171	contains similarity to Vibrio vulnificus NhaP-type Na+/H+ and K+/H+ antiporters.; TR:Q8D8X5
12	acs-17	C46F4.2	n/a	chrX 5,939,959	C. elegans ACS-17 protein; contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
13	lgc-18	T01H10.7	n/a	chrX 12,126,727	C. elegans LGC-18 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
14	F08F8.2	F08F8.2	n/a	chrIII 7,360,724	contains similarity to Pfam domain PF00368 Hydroxymethylglutaryl-coenzyme A reductase contains similarity to Interpro domains IPR004554 (Hydroxymethylglutaryl-CoA reductase, class I, catalytic), IPR009029 (Hydroxymethylglutaryl-CoA reductase, class I/II, substrate-binding), IPR002202 (Hydroxymethylglutaryl-CoA reductase, class I/II, catalytic)
15	nhr-74	C27C7.3	n/a	chrI 11,430,558	C. elegans NHR-74 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
16	F10E7.6	F10E7.6	n/a	chrII 7,113,277
17	Y54E2A.4	Y54E2A.4	n/a	chrII 14,754,890	contains similarity to Archaeoglobus fulgidus NADH oxidase (NOXA-3).; TR:O29847
18	ubxn-4	ZK353.8	n/a	chrIII 8,404,541	C. elegans UBXN-4 protein; contains similarity to Pfam domain PF00789 UBX domain contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR001012 (UBX)
19	ZK863.1	ZK863.1	n/a	chrV 12,169,192	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
20	F32G8.4	F32G8.4	n/a	chrV 10,559,356	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domain IPR000615 (Bestrophin)
21	F42C5.6	F42C5.6	n/a	chrIV 7,308,755
22	F28B3.1	F28B3.1	n/a	chrI 4,946,480	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domains IPR000010 (Proteinase inhibitor I25, cystatin), IPR000873 (AMP-dependent synthetase and ligase)
23	B0348.5	B0348.5	n/a	chrV 6,100
24	F57B10.9	F57B10.9	n/a	chrI 6,551,594	F57B10.9 is orthologous to the human gene SPARTIN (TAHCCP1; OMIM:607111), which when mutated leads to disease.
25	F26B1.5	F26B1.5	n/a	chrI 6,309,949	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
26	C06B3.2	C06B3.2	n/a	chrV 13,901,062	contains similarity to Pfam domain PF00350 Dynamin family contains similarity to Interpro domain IPR001401 (Dynamin, GTPase region)
27	fbxa-165	C08E3.8	n/a	chrII 1,615,632	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
28	lpd-9	T21C9.5	n/a	chrV 10,579,970	lpd-9 encodes a novel protein conserved amongst C. elegans, C. briggsae, and C. remanei; loss of lpd-9 activity via RNAi indicates that LPD-9 is required for fat storage and for larval growth and development.
29	tsp-3	Y39E4B.4	n/a	chrIII 13,213,403	C. elegans TSP-3 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domain IPR000301 (CD9/CD37/CD63 antigen)
30	acy-1	F17C8.1	n/a	chrIII 4,726,505	The acy-1 gene encodes a protein with 40% identity to mammalian adenylyl cyclases, most closely related to the divergent mouse isoform type IX, that affects viability, muscle contraction, locomotion, and molting; it acts genetically downstream of gsa-1 and is expressed in excitable cells.
31	scrm-2	ZK1053.5	n/a	chrI 13,235,906	scrm-2 encodes a putative phospholipid scramblase homologous to human PLSCR1-5, and paralogous to other C. elegans SCRMs (e.g., SCRM-1); in apoptotic germline cells, SCRM-2 is fully dispensable for normally rapid engulfment and largely dispensable for phosphatidylserine exposure; SCRM-2 does not bind WAH-1 in vitro, and scrm-2(tm650) mutants have no obvious phenotype.
32	F46B3.16	F46B3.16	n/a	chrV 20,630,275
33	F31D5.4	F31D5.4	n/a	chrII 4,179,466	contains similarity to Pfam domain PF01825 Latrophilin/CL-1-like GPS domain contains similarity to Interpro domain IPR000203 (GPS)
34	F52F12.7	F52F12.7	n/a	chrI 9,929,922	F52F12.7 is orthologous to the human gene STEROIDOGENIC ACUTE REGULATORY PROTEIN (STAR; OMIM:600617), which when mutated leads to disease.
35	E04D5.4	E04D5.4	n/a	chrII 10,441,286	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
36	K10C2.6	K10C2.6	n/a	chrX 6,451,568
37	ZC506.1	ZC506.1	n/a	chrX 9,961,782	contains similarity to Pfam domains PF02225 (PA domain) , PF01532 (Glycosyl hydrolase family 47) contains similarity to Interpro domains IPR001382 (Glycoside hydrolase, family 47), IPR003137 (Protease-associated PA)
38	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
39	T05E8.3	T05E8.3	n/a	chrI 5,475,882	The T05E8.3 gene encodes a divergent DEAH helicase that is (apparently) unique to Caenorhabditis; it has no well-characterized orthologs in the complete Drosophila or S. cerevisiae genomes, and no obvious orthologs in the draft human genome sequence either.
40	hsp-6	C37H5.8	n/a	chrV 4,825,414	hsp-6 encodes a mitochondrial-specific chaperone that is a member of the DnaK/Hsp70 superfamily of molecular chaperones; hsp-6 is believed to be involved in the mitochondrial unfolded protein response, as hsp-6 expression, normally broadly detected from the L1 larval through adult stages of development, is greatly increased in response to treatments that disrupt mitochondrial protein handling; loss of hsp-6 activity via RNAi results in severe growth defects with arrest at embryonic and early larval stages of development.
41	nhl-2	F26F4.7	n/a	chrIII 4,896,829	C. elegans NHL-2 protein; contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF00643 (B-box zinc finger) (2), PF01436 (NHL repeat) (4)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003649 (B-box, C-terminal), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR000315 (Zinc finger, B-box), IPR001258 (NHL repeat)
42	nsh-1	F20H11.2	n/a	chrIII 6,595,590	C. elegans NSH-1 protein; contains similarity to Pfam domain PF00271 Helicase conserved C-terminal domain contains similarity to Interpro domains IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
43	nhr-89	E03H4.13	n/a	chrI 12,440,583	C. elegans NHR-89 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
44	ugt-59	R11A8.3	n/a	chrIV 10,362,030	C. elegans UGT-59 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
45	C08B6.7	C08B6.7	n/a	chrV 10,132,247	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
46	C50F2.1	C50F2.1	n/a	chrI 3,893,803	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
47	F28G4.5	F28G4.5	n/a	chrV 16,290,444	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
48	B0222.3	B0222.3	n/a	chrV 9,140,149	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domains IPR001204 (Phosphate transporter), IPR001991 (Sodium:dicarboxylate symporter)
49	rrf-2	M01G12.12	n/a	chrI 12,102,320	rrf-2 encodes an RNA-directed RNA polymerase (RdRP) homolog of unknown function; RRF-2 is not obviously required for either somatic or germline RNAi, or for transitive RNAi.
50	grl-13	F32D1.4	n/a	chrV 4,363,652	grl-13 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-13 is expressed in larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.