UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F52E1.8	F52E1.8	0	chrV 8,393,368	contains similarity to Pfam domains PF00300 (Phosphoglycerate mutase family) , PF00328 (Histidine acid phosphatase) contains similarity to Interpro domains IPR000560 (Histidine acid phosphatase), IPR013078 (Phosphoglycerate mutase)
2	M60.7	M60.7	n/a	chrX 8,259,771	contains similarity to Pfam domains PF07525 (SOCS box) , PF00023 (Ankyrin repeat) (9)contains similarity to Interpro domains IPR002110 (Ankyrin), IPR001496 (SOCS protein, C-terminal)
3	tsp-1	C02F5.8	n/a	chrIII 8,238,638	C. elegans TSP-1 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin), IPR013305 (ABC transporter, ABCB2), IPR003091 (Voltage-dependent potassium channel)
4	zig-5	Y48A6A.1	n/a	chrIII 10,952,247	zig-5 encodes a predicted secreted protein that is a member of the immunoglobulin superfamily of proteins; a zig-5::gfp reporter fusion is expressed in a number of neurons, including PVT, VD1-13, RID, AFD, ASK, RIV, RIB, PVQ, DVA, and RIS; zig-5::gfp is detected in the PVT neuron beginning at the three-fold stage of embryogenesis and continuing throughout larval development; loss of zig-5 activity in large-scale RNAi screens has been reported to result in low levels of embryonic lethality.
5	C54C6.5	C54C6.5	n/a	chrIII 3,549,652	contains similarity to Mycoplasma pulmonis Hypothetical protein MYPU_4440.; TR:Q98QC2
6	pqn-98	ZK488.7	n/a	chrV 603,936	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
7	T26G10.5	T26G10.5	n/a	chrIII 9,426,015	contains similarity to Streptococcus pyogenes Hypothetical protein SPy0952.; TR:Q9A032
8	C47D2.1	C47D2.1	n/a	chrX 8,215,243
9	flp-21	C26F1.10	n/a	chrV 7,793,674	flp-21 encodes a single FMRFamide-related neuropeptide (FaRP) that serves as a ligand for NPR-1, a G protein-coupled receptor that regulates social versus solitary feeding behavior in several Caenorhabditis species; genetic analysis suggests that FLP-21 acts through NPR-1 to inhibit social feeding behavior; FLP-21 is expressed in the ADL, ASE and ASH sensory neurons, the URA motor neurons, the MC, M2 and M4 pharyngeal neurons, and the intestine; flp-21 encodes the only FMRFamide-related neuropeptide (FaRP) encoded by the C. elegans genome that activates both the social (215F) and the solitary (215V) forms of NPR-1 in both Xenopus oocytes and pharyngeal assays.
10	F20A1.10	F20A1.10	n/a	chrV 7,052,940
11	fipr-23	C37A5.4	n/a	chrI 14,153,722	C. elegans FIPR-23 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
12	F20B6.4	F20B6.4	n/a	chrX 4,194,407
13	K12B6.4	K12B6.4	n/a	chrV 6,280,741
14	nlp-8	D2005.2	n/a	chrI 7,801,131	C. elegans NLP-8 protein ;
15	F43G9.5	F43G9.5	n/a	chrI 8,615,863	F43G9.5 encodes a NUDIX hydrolase that that inhibits DHC-1 in vivo, and is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; F43G9.5(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that F43G9.5 negatively regulates dynein; while loss of F43G9.5 function has no obvious effect on lifespan, dauer formation, or fat storage, F43G9.5 is required for embryonic development, fertility, and general health in mass RNAi assays.
16	ins-18	T28B8.2	n/a	chrI 8,148,533	ins-18 encodes one of 40 C. elegans insulin/IGF-like peptides; INS-18, along with INS-1, are the only two C. elegans insulins that contain a C peptide, characteristic of mammalian insulins, connecting the B and A chains; overexpression of ins-18 induces dauer arrest at 26 degrees C and enhances the dauer arrest seen in a daf-2 mutant at 20 degrees C, suggesting that INS-18 functions to antagonize DAF-2 receptor signaling; ins-18::gfp reporters are expressed in neurons and the intestine.
17	F42C5.3	F42C5.3	n/a	chrIV 7,286,758	contains similarity to Homo sapiens Intersectin 1 short form transcript variant 8; ENSEMBL:ENSP00000370685
18	F47B8.3	F47B8.3	n/a	chrV 14,322,155	contains similarity to Pfam domain PF00462 Glutaredoxin contains similarity to Interpro domains IPR002109 (Glutaredoxin), IPR012336 (Thioredoxin-like fold)
19	xbx-3	M04D8.6	n/a	chrIII 10,036,315	C. elegans XBX-3 protein ;
20	C02B8.3	C02B8.3	n/a	chrX 8,139,820
21	flp-14	Y37D8A.15	n/a	chrIII 12,912,600	flp-14 encodes four copies of a single FMRFamide-related short peptide neurotransmitter; FLP-14 can increase pharyngeal action potential frequency, although its exact role in C. elegans neurotransmission is not yet clear.
22	nas-28	F42A10.8	n/a	chrIII 6,182,093	C. elegans NAS-28 protein; contains similarity to Pfam domain PF01400 Astacin (Peptidase family M12A) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
23	C39D10.2	C39D10.2	n/a	chrX 7,889,123
24	fipr-22	C37A5.2	n/a	chrI 14,155,893	C. elegans FIPR-22 protein ; contains similarity to Homo sapiens Keratin-associated protein 20-2; ENSEMBL:ENSP00000330746
25	C55A1.6	C55A1.6	n/a	chrV 15,648,434	contains similarity to Lactococcus lactis Protein maturation protein.; TR:Q9CEV9
26	C54G4.5	C54G4.5	n/a	chrI 7,996,207
27	F10F2.4	F10F2.4	n/a	chrIII 4,624,572	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
28	tag-243	T04A8.4	n/a	chrIII 4,686,618	C. elegans TAG-243 protein; contains similarity to Interpro domain IPR000637 (HMG-I and HMG-Y, DNA-binding)
29	F18G5.6	F18G5.6	n/a	chrX 9,263,128
30	ida-1	B0244.2	n/a	chrIII 5,760,627	ida-1 encodes a protein tyrosine phosphatase-like receptor, orthologous to the mammalian type I diabetes autoantigens IA-2 and phogrin that are expressed in dense core vesicles of neuroendocrine tissue and involved in regulated protein secretion; in C. elegans, IDA-1 appears to be required for regulating presynaptic neurotransmission and in particular, for the neuropeptidergic control of egg-laying; ida-1 interacts genetically with unc-31 and unc-64, which encode proteins required for dense core vesicle fusion and exocytosis; ida-1 expression is detected in a subset of neurons in the anterior nerve ring, the ventral nerve cord, the tail, and the vulva, including the VC vulval motoneurons and the HSN egg-laying neurons; ida-1 is also detected in the vulval uv1 cells, non-neuronal cells that contain neurosecretory-like vesicles.
31	C15B12.4	C15B12.4	n/a	chrX 6,472,014	contains similarity to Interpro domain IPR000158 (Cell division protein FtsZ, N-terminal)
32	ZK1248.1	ZK1248.1	n/a	chrII 5,843,377	ZK1248.1 encodes a neprilysin; neprilysins are thermolysin-like zinc metallopeptidases, found on the outer surface of animal cells, that negatively regulate small signalling peptides (e.g., enkephalin, tachykinin, insulin, and natriuretic peptides) by cleaving them; ZK1248.1 has no clear orthologs in other organisms.
33	flp-24	C24A1.1	n/a	chrIII 725,550	C. elegans FLP-24 protein ;
34	far-3	F15B9.1	n/a	chrV 12,997,151	C. elegans FAR-3 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
35	T21C9.11	T21C9.11	n/a	chrV 10,594,469	contains similarity to Homo sapiens Popeye domain containing protein 3; ENSEMBL:ENSP00000254765
36	K02A6.2	K02A6.2	n/a	chrX 8,224,536
37	F57H12.4	F57H12.4	n/a	chrIV 7,971,993	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001920 (Asp/Glu racemase), IPR009126 (Cholecystokinin receptor), IPR000276 (GPCR, rhodopsin-like)
38	F07G11.7	F07G11.7	n/a	chrV 7,303,485	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
39	F22B7.3	F22B7.3	n/a	chrIII 8,649,167
40	F19F10.1	F19F10.1	n/a	chrV 7,563,460	contains similarity to Pfam domain PF00178 Ets-domain contains similarity to Interpro domains IPR000418 (Ets), IPR011991 (Winged helix repressor DNA-binding)
41	T21C12.3	T21C12.3	n/a	chrIII 10,538,504	contains similarity to Leptospira interrogans Hypothetical protein.; TR:Q8EZD2
42	T10G3.1	T10G3.1	n/a	chrV 13,471,322	contains similarity to Saccharomyces cerevisiae interacts with Sin1p; SGD:YER047C
43	sul-2	D1014.1	n/a	chrV 8,158,775	sul-2 is orthologous to the human gene ARYLSULFATASE A (ARSA; OMIM:250100), which when mutated leads to metachromatic leukodystrophy.
44	aqp-3	Y69E1A.7	n/a	chrIV 10,962,555	aqp-3 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases water or glycerol permeability five- to seven-fold; loss of AQP-3 activity via mutation or RNAi results in no obvious defects; however, AQP-3, in conjunction with AQP-2, AQP-4, and AQP-8, is weakly required for recovery from hypotonic stress; AQP-3 is expressed in the intestine, excretory cell, seminal vesicle, and vas deferens.
45	clec-110	F17B5.5	n/a	chrI 13,204,938	C. elegans CLEC-110 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
46	drn-1	C54A12.4	n/a	chrII 5,271,026	C. elegans DRN-1 protein; contains similarity to Pfam domain PF00071 Ras family contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
47	F47E1.2	F47E1.2	n/a	chrX 9,059,694	contains similarity to Pfam domain PF03137 Organic Anion Transporter Polypeptide (OATP) family contains similarity to Interpro domains IPR004156 (Organic anion transporter polypeptide OATP), IPR016196 (MFS general substrate transporter)
48	C07A12.2	C07A12.2	n/a	chrX 4,545,119
49	M7.8	M7.8	n/a	chrIV 11,094,455	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
50	nhr-260	C38C3.9	n/a	chrV 1,510,828	C. elegans NHR-260 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)