UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	rgs-8.1	F52D2.2	9e-124	chrX 1,953,014	C. elegans RGS-8.1 protein; contains similarity to Interpro domains IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
2	F14D7.2	F14D7.2	n/a	chrV 14,292,817	contains similarity to Homo sapiens Similar to Dentin sialophosphoprotein preproprotein; ENSEMBL:ENSP00000282478
3	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
4	R04D3.4	R04D3.4	n/a	chrX 13,288,277	contains similarity to Rattus norvegicus Copper-transporting ATPase 1 (EC 3.6.3.4) (Copper pump 1) (Menkessdisease-associated protein homolog).; SW:AT7A_RAT
5	F08F3.6	F08F3.6	n/a	chrV 5,419,025	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
6	E02H4.6	E02H4.6	n/a	chrX 14,251,350	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
7	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
8	rgs-9	ZC53.7	2e-58	chrX 1,916,166	C. elegans RGS-9 protein; contains similarity to Interpro domains IPR015905 (Isoleucyl-tRNA synthetase, class Ia, N-terminal), IPR016137 (Regulator of G protein signalling superfamily), IPR000342 (Regulator of G protein signalling)
9	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
10	C31G12.1	C31G12.1	n/a	chrV 18,180,590	contains similarity to Kaposi's sarcoma-associated herpesvirus K1 glycoprotein (Fragment).; TR:Q9WHA1
11	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
12	T12G3.6	T12G3.6	n/a	chrIV 12,030,485	contains similarity to Helicobacter pylori Hypothetical protein HP1128.; TR:O25753
13	F14H3.6	F14H3.6	n/a	chrV 16,058,082	contains similarity to Homo sapiens Similar to golgi SNAP receptor complex member 2; ENSEMBL:ENSP00000318814
14	C17E7.4	C17E7.4	n/a	chrV 3,893,699
15	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
16	F54D10.5	F54D10.5	n/a	chrII 3,807,652
17	clec-222	C03E10.6	n/a	chrV 11,271,884	C. elegans CLEC-222 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
18	F53F8.3	F53F8.3	n/a	chrV 20,684,555	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
19	mom-2	F38E1.7	n/a	chrV 8,357,065	mom-2 encodes a member of the Wnt family of secreted signaling glycoproteins that is required for induction of endodermal (gut) tissue in the 4-cell stage embryo; MOM-2, required in the inducing blastomere (P2) at the 4-cell stage, may be the ligand for MOM-5, a Frizzled homolog, thought to act in the receiving blastomere (EMS); MOM-2 genetically interacts in the same pathway as KIN-19, but parallel to APR-1; MOM-2 also may be a ligand for LIN-18, a Ryk homolog.
20	Y75B12B.1	Y75B12B.1	n/a	chrV 15,185,232	Y75B12B.1 encodes a probable transposase, with many C. elegans paralogs and distant similarity to rotifer and insect transposases; Y75B12B.1 has no known function in mass RNAi assays; Y75B12B.1 mRNA is stabilized by bound GLD-1.
21	C16A3.2	C16A3.2	n/a	chrIII 6,390,183	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
22	nos-2	ZK1127.1	n/a	chrII 7,066,218	nos-2 encodes one of three genes in C. elegans that contains a putative zinc-binding domain similar to the one found in Drosophila nanos; nos-2 affects incorporation of primordial germ cells into the somatic gonad, is required redundantly with nos-1 to prevent primordial germ cells from dividing in starved animals and to maintain germ cell viability during larval development in hermaphrodites and in males, and also functions together with nos-1 and nos-3 in the hermaphrodite switch from spermatogenesis to oogenesis; nos-2 is expressed in the primordial germ cells around the time of gastrulation from a maternal RNA associated with P granules, and it is expressed coordinately with nos-1in a dynamic fashion until the embryonic 200-cell stage.
23	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
24	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
25	skr-15	F54D10.1	n/a	chrII 3,824,456	The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
26	pzf-1	T05G11.1	n/a	chrV 15,927,495	C. elegans PZF-1 protein; contains similarity to Pfam domain PF00751 DM DNA binding domain contains similarity to Interpro domain IPR001275 (DM DNA-binding)
27	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
28	K04C1.5	K04C1.5	n/a	chrX 14,248,813	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR017442 (Serine/threonine protein kinase-related)
29	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
30	F27C8.6	F27C8.6	n/a	chrIV 9,587,998	F27C8.6 encodes a putative arylacetamide deacetylase and microsomal lipase; F27C8.6 is required for sperm to normally migrate towards a PUFA-based signal exuded by oocytes; F27C8.6(RNAi) hermaphrodites are infertile, both through aberrant loss of their own sperm and through failure of males to effectively inseminate them.
31	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
32	F48C1.5	F48C1.5	n/a	chrI 5,317,876
33	nspc-9	F42F12.1	n/a	chrX 12,343,078	C. elegans NSPC-9 protein ;
34	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
35	fbxa-170	C36C9.3	n/a	chrX 1,677,298	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
36	T25E12.5	T25E12.5	n/a	chrV 16,745,714	contains similarity to Pfam domain PF01501 Glycosyl transferase family 8 contains similarity to Interpro domain IPR002495 (Glycosyl transferase, family 8)
37	Y6G8.3	Y6G8.3	n/a	chrV 17,602,355	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
38	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
39	F54D10.7	F54D10.7	n/a	chrII 3,820,711	contains similarity to Pfam domain PF00240 Ubiquitin family contains similarity to Interpro domain IPR000626 (Ubiquitin)
40	C04B4.2	C04B4.2	n/a	chrX 12,284,223	contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
41	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
42	ZK643.2	ZK643.2	n/a	chrIII 8,957,012	contains similarity to Pfam domain PF00383 Cytidine and deoxycytidylate deaminase zinc-binding region contains similarity to Interpro domains IPR016192 (APOBEC/CMP deaminase, zinc-binding), IPR002125 (CMP/dCMP deaminase, zinc-binding), IPR016473 (dCMP deaminase), IPR016193 (Cytidine deaminase-like), IPR015517 (Cytidine deaminase)
43	F41C6.3	F41C6.3	n/a	chrX 6,870,780
44	F19H6.4	F19H6.4	n/a	chrX 12,366,324	contains similarity to Pfam domain PF02544 3-oxo-5-alpha-steroid 4-dehydrogenase contains similarity to Interpro domains IPR013838 (Beta tubulin, autoregulation binding site), IPR001104 (3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal), IPR016636 (3-oxo-5-alpha-steroid 4-dehydrogenase)
45	rmd-1	T05G5.7	n/a	chrIII 9,759,548	C. elegans RMD-1 protein; contains similarity to Interpro domain IPR011990 (Tetratricopeptide-like helical)
46	B0416.4	B0416.4	n/a	chrX 9,279,335	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR000533 (Tropomyosin), IPR001841 (Zinc finger, RING-type), IPR000956 (Stathmin), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
47	taf-11.2	K10D3.3	n/a	chrI 7,133,402	C. elegans TAF-11.2 protein; contains similarity to Pfam domain PF04719 hTAFII28-like protein conserved region contains similarity to Interpro domains IPR006809 (TAFII28-like protein), IPR009072 (Histone-fold)
48	T05F1.2	T05F1.2	n/a	chrI 9,623,710	T05F1.2 encodes a novel protein; in situ hybridization studies indicate that T05F1.2 mRNA is expressed in the medial germline.
49	cdk-1	T05G5.3	n/a	chrIII 9,747,971	cdk-1 encodes a cyclin-dependent kinase, orthologous to and functionally interchangeable with CDC28 from S. cerevisiae; CDK-1 is required for cell-cycle progression through M phase in both meiosis and mitosis.
50	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.