UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F52D10.2	F52D10.2	5e-164	chrX 11,590,643	contains similarity to Interpro domains IPR011993 (Pleckstrin homology-type), IPR006020 (Phosphotyrosine interaction region)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	K09E3.6	K09E3.6	n/a	chrX 17,114,487	contains similarity to Pfam domain PF03353 DUF278 contains similarity to Interpro domain IPR005020 (Protein of unknown function DUF278)
4	efn-4	F56A11.3	n/a	chrIV 563,657	efn-4 encodes a member of the ephrin family of ligands that affects neuroblast migrations during closure of the ventral gastrulation cleft and subsequent epidermal morphogenesis, possibly functioning independently of EFN-1, EFN-2, EFN-3, and the VAB-1 receptor during morphogenesis; can interact with VAB-1 in vitro, and is expressed in neural and epidermal precursors at the 100-cell stage, in head neurons, pharyngeal cells, lateral and tail neurons, and in the ectoderm during epidermal enclosure.
5	K08H10.9	K08H10.9	n/a	chrV 9,992,294	contains similarity to Pfam domain PF04051 Transport protein particle (TRAPP) component, Bet3 contains similarity to Interpro domain IPR007194 (Transport protein particle (TRAPP) component, Bet3)
6	hst-2	C34F6.4	n/a	chrX 11,205,546	hst-2 encodes the C. elegans ortholog of the heparan sulfate modifying enzyme 2O-sulfotransferase; by homology, HST-2 is predicted to function in heparan sulfate biosynthesis by catalyzing the chain-modifying sulfation of the C2 hydroxyl group of hexuronic acid; during development, hst-2 activity is required for normal body size, cell migration, and nervous system development; an hst-2::gfp reporter fusion is first expressed in embryos, continuing on through adulthood; expression is detected in many tissues, including the pharynx, hypodermis, muscles, vulva, and distal tip cells (DTCs) of the somatic gonad.
7	C14C6.3	C14C6.3	n/a	chrV 544,415
8	sdz-30	T04D3.2	n/a	chrI 13,307,433	C. elegans SDZ-30 protein; contains similarity to Interpro domain IPR002048 (Calcium-binding EF-hand)
9	T15B7.15	T15B7.15	n/a	chrV 6,837,660	contains similarity to Interpro domain IPR000533 (Tropomyosin)
10	T11B7.1	T11B7.1	n/a	chrIV 8,841,747	contains similarity to Mus musculus Girdin (Girders of actin filament) (Coiled-coil domain-containingsprotein 88A) (Akt phosphorylation enhancer) (APE) (Hook-relatedsprotein 1) (HkRP1) (G alpha-interacting vesicle-associated protein)s(GIV).; SW:Q5SNZ0
11	F37B4.10	F37B4.10	n/a	chrV 2,876,718	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
12	mop-25.2	Y53C12A.4	n/a	chrII 9,702,750	mop-25.2 encodes a Mo25 protein that inhibits DHC-1 in vivo; MOP-25.2 is orthologous to fission yeast Mo25p, budding yeast Hym1p, Aspergillus nidulans HymA, human CAB39, and human CAB39L; MOP-25.2 is paralogous to MOP-25.1 and (more distantly) MOP-25.3; mop-25.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that MOP-25.2 negatively regulates dynein; in early embryos, MOP-25.2 is associated with the midbody and spindle poles after cytokinesis; MOP-25.2 shares a redundant function with MOP-25.1 in fertility and embryonic viability; in mass RNAi assays, MOP-25.2 is required for normal locomotion, body coloration, speed, and body size.
13	C14A11.2	C14A11.2	n/a	chrX 2,803,965
14	gly-17	T15D6.3	n/a	chrI 12,377,779	gly-17 encodes a protein similar to 2/I N-acetylglucosaminyltransferase.
15	C24H12.2	C24H12.2	n/a	chrII 437,796
16	C26B9.6	C26B9.6	n/a	chrX 5,334,221	contains similarity to Pfam domains PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF02825 (WWE domain) (2)contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR004170 (WWE), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
17	T08E11.5	T08E11.5	n/a	chrII 1,822,035
18	egl-26	C23H3.1	n/a	chrII 70,469	egl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function.
19	Y75B8A.5	Y75B8A.5	n/a	chrIII 12,116,403	contains similarity to Interpro domain IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal)
20	F28C6.1	F28C6.1	n/a	chrII 8,591,963	F28C6.1 encodes an AP-2-like transcription factor that is ~60% identical to that of F28C6.2 which lies immediately adjacent to F28C6.1 on chromosome II; loss of F28C6.1 activity via large-scale RNAi experiments results in embryonic and larval lethality.
21	T21C9.1	T21C9.1	n/a	chrV 10,577,614	contains similarity to Pfam domain PF00595 PDZ domain (Also known as DHR or GLGF) contains similarity to Interpro domain IPR001478 (PDZ/DHR/GLGF)
22	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
23	K03A11.1	K03A11.1	n/a	chrX 13,053,489	contains similarity to Interpro domain IPR001130 (Deoxyribonuclease, TatD-related)
24	ins-34	F52B11.6	n/a	chrIV 14,107,090	ins-34 encodes an insulin-like peptide.
25	E01G6.3	E01G6.3	n/a	chrX 12,243,099	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR002018 (Carboxylesterase, type B), IPR016196 (MFS general substrate transporter)
26	R07C3.7	R07C3.7	n/a	chrII 916,765
27	cpf-2	F56A8.6	n/a	chrIII 13,267,824	C. elegans CPF-2 protein; contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR003954 (RNA recognition, region 1), IPR000504 (RNA recognition motif, RNP-1)
28	daf-8	R05D11.1	n/a	chrI 8,586,024	daf-8 encodes a Smad protein that represses dauer development, perhaps by antagonizing DAF-3 activity, and promotes a commitment to reproductive growth; genetic interactions suggest partial functional redundancy with daf-14 with respect to the TGF-beta signaling pathway that regulates dauer formation.
29	B0281.8	B0281.8	n/a	chrII 2,312,169	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR000315 (Zinc finger, B-box), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
30	srd-19	F53F1.11	n/a	chrV 13,428,164	C. elegans SRD-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
31	fzy-1	ZK177.6	n/a	chrII 5,502,742	fzy-1 encodes an ortholog of S. cerevisiae Cdc20p that is required for the metaphase-to-anaphase transition, the deposition of extra meiotic chromosomes to polar bodies, and postembryonic vulval development; on the basis of orthology, FZY-1 is predicted to regulate anaphase-promoting complex (APC); FZY-1 protein is found in early embryonic cells at prometaphase and metaphase of mitosis and meiosis I, being localized to condensed chromosomes in prometaphase, and chromosomes on the metaphase plate during metaphase; FZY-1 binds IFY-1 and MDF-2 in yeast two-hybrid experiments; the missense fzy-1(h1983) mutation suppresses the lethal phenotype of mdf-1; fzy-1(RNAi) animals have vulval defects reflecting those seen in homozygotes for mat-3(ku233), whereas mat-3(ku233) is partly suppressed by RNAi of the fzy-1 paralog fzr-1.
32	ZK563.5	ZK563.5	n/a	chrX 3,378,206	contains similarity to Aedes aegypti Putative uncharacterized protein.; TR:Q17A46
33	C14F11.2	C14F11.2	n/a	chrX 6,211,298	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) (6), PF00307 (Calponin homology (CH) domain) contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR016146 (Calponin-homology), IPR001715 (Calponin-like actin-binding), IPR003590 (Leucine-rich repeat, ribonuclease inhibitor subtype)
34	C07E3.6	C07E3.6	n/a	chrII 10,368,675	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
35	prx-14	R07H5.1	n/a	chrIV 11,183,588	C. elegans PRX-14 protein; contains similarity to Pfam domain PF04695 Peroxisomal membrane anchor protein (Pex14p) conserved region contains similarity to Interpro domain IPR006785 (Peroxisome membrane anchor protein Pex14p, N-terminal)
36	T05B4.8	T05B4.8	n/a	chrV 4,115,949	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
37	Y17G7B.4	Y17G7B.4	n/a	chrII 11,995,419	contains similarity to Pfam domain PF01916 Deoxyhypusine synthase contains similarity to Interpro domain IPR002773 (Deoxyhypusine synthase)
38	F44F1.4	F44F1.4	n/a	chrI 13,264,689	contains similarity to Sulfolobus solfataricus DNA double-strand break repair rad50 ATPase.; SW:Q97WH0
39	tag-246	ZK1128.5	n/a	chrIII 10,121,745	ZK1128.5/tag-246 encodes an ortholog of SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D (SMARCD) proteins; ZK1128.5/TAG-246 is required for full levels of LIN-3/EGF signalling during vulval development, though this effect is only visible in genetically sensitized backgrounds.
40	T02G6.7	T02G6.7	n/a	chrI 11,828,074	contains similarity to Pfam domains PF00337 (Galactoside-binding lectin) , PF08277 (PAN-like domain) contains similarity to Interpro domains IPR006583 (CW), IPR001079 (Galectin, galactose-binding lectin), IPR013320 (Concanavalin A-like lectin/glucanase, subgroup), IPR008985 (Concanavalin A-like lectin/glucanase)
41	R01B10.2	R01B10.2	n/a	chrV 6,042,173
42	R05D11.5	R05D11.5	n/a	chrI 8,592,502	contains similarity to Pfam domain PF05620 Protein of unknown function (DUF788) contains similarity to Interpro domain IPR008506 (Protein of unknown function DUF788)
43	F23D12.2	F23D12.2	n/a	chrX 14,418,796	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
44	str-255	C45H4.15	n/a	chrV 2,162,667	C. elegans STR-255 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000301 (CD9/CD37/CD63 antigen)
45	F44A6.3	F44A6.3	n/a	chrX 10,213,400	contains similarity to Human parainfluenza 1 virus RNA polymerase alpha subunit (EC 2.7.7.48) (Nucleocapsidsphosphoprotein).; SW:RRPP_PI1HB
46	R166.3	R166.3	n/a	chrII 10,538,486	The R166.3 gene encodes an unfamiliar protein, with homologs in yeast and archaea, that is orthologous to the human gene ALPORT SYNDROME, MENTAL RETARDATION, MIDFACE HYPOPLASIA, AND ELLIPTOCYTOSIS CHROMOSOMAL REGION GENE 1 (AMMECR1; OMIM:300195); AMMECR1, when mutated, may be at least partially responsible for mental retardation, midface hypoplasia, or elliptocytosis.
47	Y53C12C.1	Y53C12C.1	n/a	chrII 9,827,141	Y53C12C.1 encodes a divergent paired-like homeodomain protein that does not belong to the Q50, K50, or S50 classes; it has no obvious function in mass RNAi assays.
48	str-125	T05E12.1	n/a	chrV 17,075,114	C. elegans STR-125 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
49	C02B8.2	C02B8.2	n/a	chrX 8,144,673
50	Y116A8C.40	Y116A8C.40	n/a	chrIV 17,147,619	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)