UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F52C12.2	F52C12.2	1e-121	chrIV 1,956,651	contains similarity to Pfam domains PF04068 (Possible metal-binding domain in RNase L inhibitor, RLI) , PF04034 (Domain of unknown function (DUF367)) contains similarity to Interpro domains IPR007209 (Possible metal-binding region in RNase L inhibitor, RLI), IPR007177 (Protein of unknown function DUF367)
2	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
3	F23F12.3	F23F12.3	n/a	chrIII 6,504,028	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
4	W04B5.4	W04B5.4	n/a	chrIII 2,408,633	W04B5.4 encodes a putative mitochondrial ribosomal protein L30 that inhibits DHC-1 in vivo; W04B5.4 is orthologous to human MRPL3; W04B5.4(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that W04B5.4 negatively regulates dynein; W04B5.4 is required for embryonic and larval development in mass RNAi assays.
5	pro-1	R166.4	n/a	chrII 10,540,649	pro-1 encodes a WD-repeat-containing protein that is orthologous to Saccharomyces cerevisiae IPI3; pro-1 activity is required for ribosome biogenesis and specifically, for efficient processing of intervening sequence 2 (ITS2) from rRNA intermediates during 26S rRNA maturation; during development, pro-1 is essential for larval growth, fertility, and normal cell division patterns; in addition, pro-1 is required cell autonomously in the somatic gonad for proper spatial and temporal regulation of germline development and proliferation; a pro-1 promoter::gfp fusion construct reveals that pro-1 is widely expressed in the embryo as well as in every major post-embryonic lineage including the somatic gonad.
6	ugt-11	T19H12.10	n/a	chrV 4,893,822	C. elegans UGT-11 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
7	T20H4.5	T20H4.5	n/a	chrIII 7,233,493	T20H4.5 gene encodes a 23 kDa subunit of mitochondrial complex I that is required for oxidative phosphorylation and for resistance to volatile anesthetics; T20H4.5 is orthologous to human NDUFS8 (OMIM:602141, mutated in Leigh syndrome).
8	tag-131	H38K22.3	n/a	chrIII 4,318,987	C. elegans TAG-131 protein; contains similarity to Pfam domain PF00173 Cytochrome b5-like Heme/Steroid binding domain contains similarity to Interpro domain IPR001199 (Cytochrome b5)
9	npp-4	Y54E5A.4	n/a	chrI 14,703,902	C. elegans NPP-4 protein; contains similarity to Interpro domains IPR001778 (Pollen allergen Poa pIX/Phl pVI, C-terminal), IPR007758 (Nucleoporin, Nsp1-like, C-terminal)
10	F56E10.1	F56E10.1	n/a	chrV 105,397	contains similarity to Neurospora crassa Protein bfr-2.; SW:Q7S6P8
11	C05G5.1	C05G5.1	n/a	chrX 14,737,200	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
12	C05D11.10	C05D11.10	n/a	chrIII 6,431,356	contains similarity to Interpro domain IPR016027 (Nucleic acid-binding, OB-fold-like)
13	taf-2	Y37E11B.4	n/a	chrIV 3,588,951	taf-2 encodes a member of the peptidase M1 family, a predicted aminopeptidase with similarity to human TBP-associated factor 2.
14	K09C4.5	K09C4.5	n/a	chrX 3,284,155	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
15	twk-28	C52B9.6	n/a	chrX 4,276,975	C. elegans TWK-28 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
16	T10D4.6	T10D4.6	n/a	chrII 3,121,247	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR009057 (Homeodomain-like)
17	hint-1	F21C3.3	n/a	chrI 7,280,150	C. elegans HINT-1 protein; contains similarity to Pfam domain PF01230 HIT domain contains similarity to Interpro domains IPR001310 (Histidine triad (HIT) protein), IPR011151 (Histidine triad motif), IPR011146 (Histidine triad-like motif)
18	F07E5.5	F07E5.5	n/a	chrII 2,056,499	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR013084 (Zinc finger, CCHC retroviral-type), IPR001878 (Zinc finger, CCHC-type)
19	fbxa-216	Y47H9C.10	n/a	chrI 11,902,379	C. elegans FBXA-216 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
20	C34C12.8	C34C12.8	n/a	chrIII 3,460,983	contains similarity to Pfam domain PF01025 GrpE contains similarity to Interpro domains IPR009012 (GrpE nucleotide exchange factor, head), IPR013805 (GrpE nucleotide exchange factor, coiled-coil), IPR000740 (GrpE nucleotide exchange factor)
21	F57G8.5	F57G8.5	n/a	chrV 16,340,228	contains similarity to Pfam domain PF00999 Sodium/hydrogen exchanger family contains similarity to Interpro domain IPR006153 (Sodium/hydrogen exchanger)
22	mtss-1	PAR2.1	n/a	chrIII 8,768,640	C. elegans MTSS-1 protein; contains similarity to Pfam domain PF00436 Single-strand binding protein family contains similarity to Interpro domains IPR000424 (Primosome PriB/single-strand DNA-binding), IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold), IPR011344 (Single-strand DNA-binding)
23	T20B12.1	T20B12.1	n/a	chrIII 7,388,607	contains similarity to Pfam domains PF07719 (Tetratricopeptide repeat) (3), PF00515 (Tetratricopeptide repeat) (4)contains similarity to Interpro domains IPR011990 (Tetratricopeptide-like helical), IPR001664 (Intermediate filament protein), IPR008940 (Protein prenyltransferase), IPR001440 (Tetratricopeptide TPR-1), IPR001356 (Homeobox), IPR013105 (Tetratricopeptide TPR2), IPR013026 (Tetratricopeptide region)
24	C01F1.2	C01F1.2	n/a	chrII 4,300,243	C01F1.2 is orthologous to the human gene SCO (CYTOCHROME OXIDASE DEFICIENT, YEAST) HOMOLOG 1 (SCO1; OMIM:603644), which when mutated leads to early-onset hepatic failure; the C01F1.2 protein is predicted to be mitochondrial with 68% accuracy.
25	cln-3.3	ZC190.1	n/a	chrV 8,684,539	cln-3.3 encodes a predicted transmembrane protein that comprises one of three C. elegans homologs of human CLN3, (OMIM:607042, mutations are associated with Batten disease (also known as juvenile neuronal ceroid lipofuscinosis), a recessively inherited childhood neurodegenerative lysosomal storage disease); as loss of cln-3.3 via large-scale RNAi screens results in no obvious abnormalities, the precise role of cln-3.3 in C. elegans development and/or behavior is not yet known.
26	C27F2.4	C27F2.4	n/a	chrIII 4,959,381	contains similarity to Pfam domains PF08242 (Methyltransferase domain) , PF08241 (Methyltransferase domain) contains similarity to Interpro domains IPR013217 (Methyltransferase type 12), IPR013216 (Methyltransferase type 11)
27	srd-72	Y45G12C.9	n/a	chrV 2,533,025	C. elegans SRD-72 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR001614 (Myelin proteolipid protein PLP), IPR003002 (7TM chemoreceptor, subfamily 1), IPR002016 (Haem peroxidase, plant/fungal/bacterial)
28	F53F1.3	F53F1.3	n/a	chrV 13,409,019	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
29	C45E5.1	C45E5.1	n/a	chrIV 5,745,740	contains similarity to Pfam domain PF00702 haloacid dehalogenase-like hydrolase contains similarity to Interpro domains IPR006357 (HAD-superfamily hydrolase, subfamily IIA), IPR005834 (Haloacid dehalogenase-like hydrolase)
30	E02C12.6	E02C12.6	n/a	chrV 9,370,290	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like)
31	C52B9.4	C52B9.4	n/a	chrX 4,262,578	contains similarity to Pfam domain PF06814 Lung seven transmembrane receptor contains similarity to Interpro domains IPR009637 (Transmembrane receptor, eukaryota), IPR008983 (Tumour necrosis factor-like)
32	figl-1	F32D1.1	n/a	chrV 4,343,730	F32D1.1 encodes an homolog of human SPASTIN (OMIM:604277, mutated in spastic paraplegia), FIDGETIN (OMIM:605295, mutated in fidget mice), and FIDGETIN-LIKE-1, and of Drosophila SPASTIN; recombinant F32D1.1 protein has N-ethylmaleimide-sensitive ATPase activity in vitro, which is strongly dependent on the C368 residue immediately C-terminal to its Walker A motif; F32D1.1 is required for persistence of the germline in RNAi assays.
33	gly-19	F22D6.12	n/a	chrI 7,113,932	gly-19 encodes a protein similar to 2/I N-acetylglucosaminyltransferase; it is probably coexpressed with gly-18 in the anal sphincter muscle.
34	R12E2.12	R12E2.12	n/a	chrI 4,174,271	contains similarity to Interpro domain IPR000529 (Ribosomal protein S6)
35	pssy-2	T27E9.5	n/a	chrIII 13,473,420	C. elegans PSSY-2 protein; contains similarity to Pfam domain PF03034 Phosphatidyl serine synthase contains similarity to Interpro domain IPR004277 (Phosphatidyl serine synthase)
36	M04C9.3	M04C9.3	n/a	chrI 9,353,710	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like), IPR000816 (Peptidase C15, pyroglutamyl peptidase I)
37	Y6B3B.9	Y6B3B.9	n/a	chrI 13,743,033	contains similarity to Pfam domain PF04031 Las1-like contains similarity to Interpro domain IPR007174 (Las1-like)
38	F55C5.8	F55C5.8	n/a	chrV 12,290,267	contains similarity to Drosophila melanogaster Flybase gene name is Srp68-PA;; FLYBASE:CG5064
39	C49A9.5	C49A9.5	n/a	chrIV 6,215,077	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
40	inx-15	R12E2.9	n/a	chrI 4,160,065	C. elegans INX-15 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
41	mtr-4	W08D2.7	n/a	chrIV 9,828,133	C. elegans MTR-4 protein; contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) , PF08148 (DSHCT (NUC185) domain) , PF00271 (Helicase conserved C-terminal domain) contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR002048 (Calcium-binding EF-hand), IPR016438 (RNA helicase, ATP-dependent, SK12/DOB1), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR012961 (DSH, C-terminal), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
42	cacn-1	W03H9.4	n/a	chrII 14,137,700	cacn-1 encodes an ortholog of Drosophila CACTIN and human C19orf29 that is required for normal distal tip cell migration, embryonic viability, fertility, locomotion, vulval morphogenesis, and normally rapid growth; like CACTIN, CACN-1 contains predicted coiled-coil domains, but otherwise lacks recognizable similarity to known proteins.
43	F54F2.7	F54F2.7	n/a	chrIII 8,806,716	contains similarity to Interpro domain IPR011053 (Single hybrid motif)
44	R09A8.1	R09A8.1	n/a	chrX 12,615,226	contains similarity to Homo sapiens FLASH; ENSEMBL:ENSP00000237177
45	F44E2.3	F44E2.3	n/a	chrIII 8,828,256	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	C56G3.2	C56G3.2	n/a	chrX 7,365,880	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
47	eif-3.F	D2013.7	n/a	chrII 9,332,730	C. elegans EIF-3.F protein; contains similarity to Pfam domain PF01398 Mov34/MPN/PAD-1 family contains similarity to Interpro domains IPR000555 (Mov34/MPN/PAD-1), IPR003639 (Mov34-1)
48	pqn-96	ZK1236.6	n/a	chrIII 8,438,835	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).
49	clh-6	R07B7.1	n/a	chrV 12,061,778	clh-6 encodes a voltage-gated chloride channel orthologous to the human CLCN7 chloride channel (OMIM:602727, which when mutated lead to osteopetrosis); although the precise role of CLH-6 in C. elegans development and/or behavior is not yet known, CLH-6 expression is detected in two GABA-ergic neurons, RMEL and RMER, suggesting that CLH-6 could play a role in membrane excitability and/or GABA packaging; as CLH-6 is also detected in many non-neuronal tissues, such as the gut and body wall muscle, it could also have a broader role in such as processes as transepithelial transport and muscle excitation.
50	C49H3.8	C49H3.8	n/a	chrIV 7,901,218	contains similarity to Pfam domain PF00022 Actin contains similarity to Interpro domains IPR001478 (PDZ/DHR/GLGF), IPR004000 (Actin/actin-like), IPR013126 (Heat shock protein 70)