UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	fbxa-185	F47H4.4	0	chrV 17,333,561	C. elegans FBXA-185 protein; contains similarity to Pfam domains PF01485 (IBR domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR002867 (Zinc finger, C6HC-type)
2	T12A2.1	T12A2.1	n/a	chrIII 6,261,458	contains similarity to Pfam domains PF01979 (Amidohydrolase family) , PF07969 (Amidohydrolase family) contains similarity to Interpro domains IPR011550 (Amidohydrolase-like), IPR013108 (Amidohydrolase 3), IPR006680 (Amidohydrolase 1), IPR005920 (Imidazolonepropionase)
3	JC8.7	JC8.7	n/a	chrIV 13,248,845	contains similarity to Homo sapiens Uncharacterized protein C4orf27; ENSEMBL:ENSP00000261511
4	hum-1	F29D10.4	n/a	chrI 8,848,443	hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures.
5	nhr-163	C33G8.12	n/a	chrV 6,984,709	C. elegans NHR-163 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	lgc-17	T01H10.6	n/a	chrX 12,123,239	C. elegans LGC-17 protein; contains similarity to Pfam domain PF02931 Neurotransmitter-gated ion-channel ligand binding domain contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding)
7	C14B9.8	C14B9.8	n/a	chrIII 8,142,045	C14B9.8 is orthologous to the human gene PHOSPHORYLASE KINASE, LIVER, ALPHA-2 SUBUNIT (PHKA2; OMIM:306000), which when mutated leads to liver glycogenosis.
8	F45F2.5	F45F2.5	n/a	chrV 8,531,457	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
9	F25B5.5	F25B5.5	n/a	chrIII 5,944,924	contains similarity to Pfam domains PF00919 (Uncharacterized protein family UPF0004) , PF04055 (Radical SAM superfamily) , PF01938 (TRAM domain) contains similarity to Interpro domains IPR005839 (Protein of unknown function UPF0004), IPR013848 (Protein of unknown function UPF0004, N-terminal), IPR007197 (Radical SAM), IPR006638 (Elongator protein 3/MiaB/NifB), IPR002792 (Deoxyribonuclease/rho motif-related TRAM)
10	cyp-14A3	K09A11.4	n/a	chrX 13,272,959	C. elegans CYP-14A3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
11	T16H12.2	T16H12.2	n/a	chrIII 10,086,574	contains similarity to Mus musculus 2310010I16Rik protein.; TR:Q9CWH8
12	nhr-177	F16B4.1	n/a	chrV 1,611,519	C. elegans NHR-177 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
13	K12H4.2	K12H4.2	n/a	chrIII 8,047,973	contains similarity to Pfam domain PF02410 Domain of unknown function DUF143 contains similarity to Interpro domain IPR004394 (Iojap-related protein)
14	T23B12.1	T23B12.1	n/a	chrV 8,469,517	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
15	W03C9.5	W03C9.5	n/a	chrII 11,967,205	contains similarity to Arabidopsis thaliana F25C20.11 protein.; TR:Q9SAA3
16	K03B4.1	K03B4.1	n/a	chrV 4,690,455
17	srw-69	F18E3.5	n/a	chrV 7,428,134	C. elegans SRW-69 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
18	lips-3	F10F2.3	n/a	chrIII 4,617,677	C. elegans LIPS-3 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)
19	F28F8.7	F28F8.7	n/a	chrV 15,579,943	contains similarity to Pfam domain PF01448 ELM2 domain contains similarity to Interpro domain IPR000949 (ELM2)
20	fbxa-149	Y38H6C.10	n/a	chrV 20,512,556	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	Y40H7A.3	Y40H7A.3	n/a	chrIV 15,162,987	contains similarity to Pfam domain PF05050 Protein of unknown function (DUF672) contains similarity to Interpro domain IPR007744 (Protein of unknown function DUF672)
22	prg-2	C01G5.2	n/a	chrIV 6,528,248	C. elegans PRG-2 protein; contains similarity to Pfam domains PF02171 (Piwi domain) , PF02170 (PAZ domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
23	C08F11.1	C08F11.1	n/a	chrIV 13,624,656	contains similarity to Coxiella burnetii Hypothetical protein.; TR:Q83D43
24	F20G4.2	F20G4.2	n/a	chrI 7,914,259	contains similarity to Saccharomyces cerevisiae Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; SGD:YER190W
25	C35D10.1	C35D10.1	n/a	chrIII 4,880,584	contains similarity to Interpro domain IPR013784 (Carbohydrate-binding-like fold)
26	ulp-4	C41C4.6	n/a	chrII 8,132,271	C. elegans ULP-4 protein; contains similarity to Pfam domain PF02902 Ulp1 protease family, C-terminal catalytic domain contains similarity to Interpro domain IPR003653 (Peptidase C48, SUMO/Sentrin/Ubl1)
27	F48G7.4	F48G7.4	n/a	chrV 620,860
28	vps-35	F59G1.3	n/a	chrII 5,909,476	C. elegans VPS-35 protein; contains similarity to Pfam domain PF03635 Vacuolar protein sorting-associated protein 35 contains similarity to Interpro domain IPR005378 (Vacuolar protein sorting-associated protein 35)
29	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
30	csb-1	F53H4.1	n/a	chrX 15,863,557	csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells.
31	str-114	F59B1.1	n/a	chrV 3,650,602	C. elegans STR-114 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1)
32	R09E12.6	R09E12.6	n/a	chrV 767,566	contains similarity to Pfam domain PF06869 Protein of unknown function (DUF1258) contains similarity to Interpro domain IPR009667 (Protein of unknown function DUF1258)
33	Y75B8A.7	Y75B8A.7	n/a	chrIII 12,156,145	contains similarity to Pfam domain PF04006 Mpp10 protein contains similarity to Interpro domains IPR012173 (U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p), IPR007151 (Mpp10 protein)
34	cpb-3	B0414.5	n/a	chrI 5,790,196	cpb-3 encodes a CPEB orthologous to Drosophila ORB, zebrafish ZORBA, and human CPEB1, and paralogous to FOG-1 and CPB-1/2; CPB-3 inhibits physiological apoptosis in oocytes, keeping it down to a normal level of ~50% in hermaphrodite gonads; independently of apoptosis, CPB-3 is also required for normal oogenesis, sperm/oocyte switching (upstream of FEM-3), and the transistion from mitosis to meiosis by oocytes (in parallel with GLD-3); cpb-3(RNAi) results in elevated (though not 100%) physiological germ cell apoptosis, independent of CEP-1; in cpb-3(RNAi) animals, excess physiological apoptosis actually promotes fertility, since cpb-3(RNAi) hermaphrodites have larger brood sizes than those with apoptosis suppressed by ced-3(n717), and aging ced-3(n717);cpb-3(RNAi) animals have abnormal oocytes that fail to exit pachytene and proceed through diakinesis; CPB-3 is mainly cytoplasmic, and strongly expressed in pachytene oocytes; cpb-3(bt17);daz-1(tj3) hermaphrodites have a synthetic phenotype of total sterility and masculinization; CPB-3 colocalizes with DAZ-1 in vivo, coimmunoprecipitates with DAZ-1, and binds DAZ-1 in two-hybrid assays.
35	K11B4.2	K11B4.2	n/a	chrI 14,798,156	contains similarity to Tetraodon nigroviridis UPF0402 protein.; SW:Q4S3C1
36	C15C7.1	C15C7.1	n/a	chrX 3,165,079	contains similarity to Pfam domain PF05739 SNARE domain contains similarity to Interpro domains IPR000727 (Target SNARE coiled-coil region), IPR001388 (Synaptobrevin), IPR006012 (Syntaxin/epimorphin, conserved site)
37	pstk-1	Y49E10.22	n/a	chrIII 12,467,328	C. elegans PSTK-1 protein; contains similarity to Pfam domain PF08433 Chromatin associated protein KTI12 contains similarity to Interpro domain IPR013641 (Chromatin associated protein KTI12)
38	C34D4.10	C34D4.10	n/a	chrIV 7,120,692
39	secs-1	D1054.13	n/a	chrV 10,803,314	C. elegans SECS-1 protein; contains similarity to Pfam domain PF05889 Soluble liver antigen/liver pancreas antigen (SLA/LP autoantigen) contains similarity to Interpro domains IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR008829 (Soluble liver antigen/liver pancreas antigen)
40	str-19	T23D5.7	n/a	chrV 15,743,832	C. elegans STR-19 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
41	F54D12.4	F54D12.4	n/a	chrII 1,368,200
42	D2092.5	D2092.5	n/a	chrI 6,603,752	contains similarity to Interpro domains IPR002713 (FF), IPR000533 (Tropomyosin)
43	T08A9.6	T08A9.6	n/a	chrX 7,312,318	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
44	kup-1	F10C2.2	n/a	chrV 12,036,541	kup-1 encodes a novel protein that is conserved in C. briggsae, but contains no other known homologs; kup-1 is the upstream gene in an operon with pkc-1, which encodes two protein kinase C isoforms of the nPKC isotype; the polycistronic kup-1/pkc-1 mRNA is detected at low levels in embryos and larvae, but its expression greatly increases in adults; as loss of kup-1 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of kup-1 in C. elegans development and/or behavior is not yet known.
45	D1065.1	D1065.1	n/a	chrV 4,075,636	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domain IPR004878 (Protein of unknown function DUF270)
46	clec-165	F38A1.10	n/a	chrIV 1,246,135	C. elegans CLEC-165 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001680 (WD40 repeat), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
47	fbxa-95	F28F8.4	0.00000000009	chrV 15,572,053	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
48	M01E5.2	M01E5.2	n/a	chrI 13,278,606	contains similarity to Pfam domains PF01018 (GTP1/OBG) , PF01926 (GTPase of unknown function) contains similarity to Interpro domains IPR014100 (GTP-binding protein Obg/CgtA), IPR005225 (Small GTP-binding protein), IPR006169 (GTP1/OBG subdomain), IPR002917 (GTP-binding protein, HSR1-related), IPR006073 (GTP1/OBG)
49	C15C6.3	C15C6.3	n/a	chrI 12,209,642	contains similarity to Interpro domains IPR006077 (Vinculin/alpha-catenin), IPR000694 (Proline-rich region)
50	E03H4.2	E03H4.2	n/a	chrI 12,403,805	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)