UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F47G9.6	F47G9.6	0	chrV 11,330,067	contains similarity to Methanosarcina acetivorans Predicted protein.; TR:Q8TS27
2	wht-4	F02E11.1	n/a	chrII 3,280,577	C. elegans WHT-4 protein; contains similarity to Pfam domains PF01061 (ABC-2 type transporter) , PF00005 (ABC transporter) contains similarity to Interpro domains IPR003439 (ABC transporter-like), IPR003593 (AAA+ ATPase, core), IPR005284 (Pigment precursor permease), IPR013525 (ABC-2 type transporter)
3	T11F9.1	T11F9.1	n/a	chrV 11,460,688	contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
4	F41B5.6	F41B5.6	n/a	chrV 2,240,376	contains similarity to Pfam domain PF03564 Protein of unknown function (DUF1759) contains similarity to Interpro domain IPR005312 (Protein of unknown function DUF1759)
5	T27A3.6	T27A3.6	n/a	chrI 6,106,790	T27A3.6 is orthologous to the human gene MOLYBDENUM COFACTOR BIOSYSTHESIS PROTEIN E (MOCS2; OMIM:603708), which when mutated leads to disease.
6	nhr-164	C41G6.5	n/a	chrV 15,234,803	C. elegans NHR-164 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
7	C50E3.5	C50E3.5	n/a	chrV 7,591,348	contains similarity to Interpro domain IPR008108 (Type III secretion system outer membrane, B protein)
8	F23F12.8	F23F12.8	n/a	chrIII 6,485,986	F23F12.8 encodes a large (980-residue) protein, predicted to be secreted, with two chitin-binding peritrophin-A domains, separated by a low-complexity region; F23F12.8 is synthesized in larval and adult pharynx, a known site of chitin deposition; like CEJ-1 and CPG-2 in embryos, F23F12.8 might participate in chitin synthesis, and its peritrophin-A domains might enable mechanical cross-linking of chitin.
9	ina-1	F54G8.3	n/a	chrIII 9,170,331	ina-1 encodes one of two C. elegans alpha integrin subunits; during development, ina-1 activity is required for migration of a number of cell types, including neurons, coelomocyte precursors, and the distal tip cells of the somatic gonad; in addition, ina-1 is required for axon fasciculation and morphogenesis of structures such as the head, pharynx, egg-laying apparatus, and male tail; INA-1 coimmunoprecipitates with the PAT-3 beta integrin subunit suggesting that, in vivo, INA-1 and PAT-3 function as a heterodimer to regulate cell migration and tissue morphogenesis; INA-1 is expressed in many tissues, including neurons, the gonad, and the pharyngeal basement membrane; expression begins during gastrulation and continues through to adulthood.
10	C10A4.7	C10A4.7	n/a	chrX 7,414,514
11	C54E10.1	C54E10.1	n/a	chrV 18,816,778	contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
12	F55C10.4	F55C10.4	n/a	chrV 11,387,665	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
13	srw-88	T06G6.7	n/a	chrI 12,721,084	C. elegans SRW-88 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
14	F15A4.9	F15A4.9	n/a	chrII 12,480,165	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
15	sra-4	AH6.8	n/a	chrII 9,542,193	C. elegans SRA-4 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domain IPR000344 (Nematode chemoreceptor, Sra)
16	F37C12.14	F37C12.14	n/a	chrIII 7,185,248
17	F36D4.2	F36D4.2	n/a	chrV 9,401,020	contains similarity to Pfam domain PF04099 Sybindin-like family contains similarity to Interpro domains IPR011012 (Longin-like), IPR007233 (Sybindin-like protein)
18	F28H7.8	F28H7.8	n/a	chrV 10,759,739	contains similarity to Pfam domains PF01105 (emp24/gp25L/p24 family/GOLD) , PF00650 (CRAL/TRIO domain) contains similarity to Interpro domains IPR001071 (Cellular retinaldehyde binding/alpha-tocopherol transport), IPR001251 (Cellular retinaldehyde-binding/triple function, C-terminal), IPR011074 (Phosphatidylinositol transfer protein-like, N-terminal), IPR000348 (emp24/gp25L/p24)
19	K07C5.2	K07C5.2	n/a	chrV 10,340,201	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
20	gcy-8	C49H3.1	n/a	chrIV 7,930,918	gcy-8 encodes a receptor-type guanylyl cyclase that, along with gcy-18 and gcy-23, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-8 functions redundantly with gcy-18 and gcy-23, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; GCY-8 is expressed exclusively in the AFD thermosensory neurons where it localizes to sensory endings; GCY-8 expression in the AFD neurons requires activity of the TAX-2/4 cyclic nucleotide gated channel and the CMK-1 Ca2+/calmodulin-dependent protein kinase I, while maintenance of GCY-8 expression requires the OTD/OTX homeodomain protein TTX-1.
21	srbc-45	ZC455.11	n/a	chrV 12,804,041	C. elegans SRBC-45 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	W03G1.3	W03G1.3	n/a	chrIV 512,107
23	ZK550.2	ZK550.2	n/a	chrIV 17,247,626	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
24	D2085.4	D2085.4	n/a	chrII 8,667,037	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) , PF00632 (HECT-domain (ubiquitin-transferase)) contains similarity to Interpro domains IPR000569 (HECT), IPR000048 (IQ calmodulin-binding region)
25	W04G5.9	W04G5.9	n/a	chrI 11,644,012	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
26	clec-188	M199.3	n/a	chrIV 15,117,866	C. elegans CLEC-188 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR001304 (C-type lectin)
27	F54B11.7	F54B11.7	n/a	chrX 13,600,836	contains similarity to Neurospora crassa GTP cyclohydrolase I (EC 3.5.4.16) (GTP-CH-I).; SW:GCH1_NEUCR
28	sre-12	T07H8.7	n/a	chrV 6,978,417	C. elegans SRE-12 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domains IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR001680 (WD40 repeat)
29	C36B7.1	C36B7.1	n/a	chrX 7,113,827	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
30	sup-12	T22B2.4	n/a	chrX 3,906,111	sup-12 encodes an RNA-binding protein that contains a conserved RNA recognition motif (RRM); during development, SUP-12 functions to regulate muscle-specific splicing of alternative unc-60 and egl-15 pre-mRNAs; in vitro, SUP-12 can bind unc-60 and egl-15 pre-mRNAs; a sup-12::gfp promoter fusion is expressed in body wall muscle and in the pharynx; in body wall muscle, a SUP-12::GFP localizes to nuclei in a speckled pattern.
31	F52C12.3	F52C12.3	n/a	chrIV 1,950,714
32	F30A10.6	F30A10.6	n/a	chrI 9,490,547	contains similarity to Pfam domain PF02383 SacI homology domain contains similarity to Interpro domain IPR002013 (Synaptojanin, N-terminal)
33	T20F7.1	T20F7.1	n/a	chrX 16,875,523	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
34	fbxb-39	M01D1.7	n/a	chrII 1,040,136	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
35	srh-181	ZK228.6	n/a	chrV 18,475,360	C. elegans SRH-181 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
36	aps-1	F29G9.3	n/a	chrV 6,018,404	aps-1 encodes an adaptin: specifically, it encodes an ortholog of the sigma1 subunit of adaptor protein complex 1 (AP-1).
37	nhr-102	T06C12.6	n/a	chrV 15,875,252	nhr-102 encodes a nuclear receptor that is most highly conserved amongst nematode species.
38	sru-29	C50C10.2	n/a	chrV 9,812,012	C. elegans SRU-29 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
39	F41E6.9	F41E6.9	n/a	chrV 8,605,583	contains similarity to Pfam domain PF03357 Snf7 contains similarity to Interpro domain IPR005024 (Snf7)
40	F17A2.3	F17A2.3	n/a	chrX 12,308,161	contains similarity to Pfam domain PF00628 PHD-finger contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
41	C52B11.5	C52B11.5	n/a	chrX 1,274,112	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
42	srt-70	B0238.6	n/a	chrV 5,258,776	C. elegans SRT-70 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
43	B0302.5	B0302.5	n/a	chrX 17,194,125
44	clec-144	T27D12.3	n/a	chrII 11,831,976	C. elegans CLEC-144 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
45	F43D2.3	F43D2.3	n/a	chrV 14,632,476	contains similarity to Homo sapiens Orphan nuclear receptor NR1D1; ENSEMBL:ENSP00000246672
46	C29F7.7	C29F7.7	n/a	chrX 13,442,218	contains similarity to Peromyscus maniculatus Alcohol dehydrogenase 2 (EC 1.1.1.1).; SW:ADH2_PERMA
47	cyp-33E3	F42A9.4	n/a	chrIV 8,615,428	C. elegans CYP-33E3 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I)
48	ced-11	ZK512.3	n/a	chrIII 9,122,267	The ced-11 gene encodes a predicted transmembrane ion channel related to the long transient receptor potential channel (LTRPC) subfamily of TRP channels found in Drosophila and mammals; CED-11 functions as a downstream effector in the programmed cell death pathway and may play a role in affecting the morphological changes seen in the nucleus, cytoplasm, and plasma membrane of apoptotic cells.
49	kgb-1	T07A9.3	n/a	chrIV 407,854	kgb-1 encodes a serine/threonine kinase that is a member of the JNK (Jun-N-terminal kinase) subfamily of MAP (mitogen-activated protein)kinases; loss of kgb-1 activity results in temperature-sensitive sterility in hermaphrodites and males; in hermaphrodites, this sterility is associated with disorganized gonads and endomitotic oocytes that have likely failed to undergo oocyte maturation; in kgb-1 mutant males, sperm is present, but is non-functional; KGB-1 interacts in vitro with all four C. elegans germline helicases, GLH-1, -2, -3, and -4, that localize to P granules in vivo; Northern analyses indicate that kgb-1 mRNA is present in both somatic and germline tissues.
50	pqn-29	F10F2.9	n/a	chrIII 4,645,137	The protein product of this gene is predicted to contain a glutamine/asparagine (Q/N)-rich ('prion') domain, by the algorithm of Michelitsch and Weissman (as of the WS77 release of WormBase, i.e., in wormpep77).