UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F47G4.2	F47G4.2	0	chrI 14,080,352	contains similarity to Interpro domain IPR016024 (Armadillo-type fold)
2	W05H7.1	W05H7.1	n/a	chrX 1,451,500	contains similarity to Homo sapiens hypothetical protein LOC283767; ENSEMBL:ENSP00000347269
3	amx-1	R13G10.2	n/a	chrIII 3,824,311	C. elegans AMX-1 protein; contains similarity to Pfam domains PF01593 (Flavin containing amine oxidoreductase) , PF01266 (FAD dependent oxidoreductase) contains similarity to Interpro domains IPR006076 (FAD dependent oxidoreductase), IPR001613 (Flavin-containing amine oxidase), IPR000960 (Flavin-containing monooxygenase FMO), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding), IPR007526 (SWIRM)
4	sedl-1	W05H7.3	n/a	chrX 1,439,758	C. elegans SEDL-1 protein; contains similarity to Pfam domain PF04628 Sedlin, N-terminal conserved region contains similarity to Interpro domains IPR011012 (Longin-like), IPR006722 (Sedlin)
5	D2005.1	D2005.1	n/a	chrI 7,785,055	contains similarity to Pfam domain PF02137 Adenosine-deaminase (editase) domain contains similarity to Interpro domain IPR002466 (Adenosine deaminase/editase)
6	F42H10.3	F42H10.3	n/a	chrIII 8,486,094	contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF00018 (SH3 domain) , PF00880 (Nebulin repeat) (2), PF00412 (LIM domain) contains similarity to Interpro domains IPR000900 (Nebulin 35 residue motif), IPR013998 (Nebulin), IPR001452 (Src homology-3), IPR000108 (Neutrophil cytosol factor 2), IPR011511 (Variant SH3), IPR001781 (Zinc finger, LIM-type)
7	F53B1.6	F53B1.6	n/a	chrX 2,116,438	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domains IPR000209 (Peptidase S8 and S53, subtilisin, kexin, sedolisin), IPR001279 (Beta-lactamase-like)
8	ZK381.2	ZK381.2	n/a	chrIV 6,966,550	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
9	T05G5.1	T05G5.1	n/a	chrIII 9,741,123	contains similarity to Pfam domain PF00008 EGF-like domain contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR006209 (EGF-like)
10	aps-2	F02E8.3	n/a	chrX 4,458,734	aps-2 encodes an adaptin: specifically, it encodes an ortholog of the sigma2 subunit of adaptor protein complex 2 (AP2), which mediates endocytosis from the plasma membrane; APS-2 is required for embryonic and larval development and for normal body morphogenesis, but is not required for endocytosis of yolk protein in developing oocytes; APS-2 is expressed in nearly all cells during embryogenesis, but during larval and adult stages, expression is confined to neurons and some hypodermal cells, including vulval hypodermal cells during the fourth larval stage.
11	dnj-14	K02G10.8	n/a	chrX 4,710,717	This gene encodes a protein containing a DnaJ ('J') domain.
12	glit-1	F55D10.3	n/a	chrX 4,713,649	C. elegans GLIT-1 protein; contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domain IPR002018 (Carboxylesterase, type B)
13	pix-1	K11E4.4	n/a	chrX 13,730,745	C. elegans PIX-1 protein ;
14	F47C12.1	F47C12.1	n/a	chrIV 4,001,937	contains similarity to Pfam domains PF00008 (EGF-like domain) (4), PF00754 (F5/8 type C domain) , PF07645 (Calcium binding EGF domain) (2), PF07699 (GCC2 and GCC3) (3), PF00431 (CUB domain) , PF07974 (EGF-like domain) , PF02494 (HYR domain) (2), PF00084 (Sushi domain (SCR repeat)) (6)contains similarity to Interpro domains IPR001438 (EGF-like, type 2), IPR000742 (EGF-like, type 3), IPR003410 (Hyalin), IPR000436 (Sushi/SCR/CCP), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002049 (EGF-like, laminin), IPR008979 (Galactose-binding like), IPR000859 (CUB), IPR011641 (GCC2 and GCC3), IPR001881 (EGF-like calcium-binding), IPR016060 (Complement control module), IPR009030 (Growth factor, receptor), IPR013032 (EGF-like region, conserved site), IPR000421 (Coagulation factor 5/8 type, C-terminal), IPR013111 (EGF, extracellular), IPR013091 (EGF calcium-binding)
15	prx-12	F08B12.2	n/a	chrX 11,393,885	C. elegans PRX-12 protein; contains similarity to Pfam domain PF04757 Pex2 / Pex12 amino terminal region contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR017375 (Peroxisome assembly, p12), IPR006845 (Pex, N-terminal)
16	dep-1	F44G4.8	n/a	chrII 9,012,700	dep-1 encodes a class III receptor protein tyrosine phosphatase (R-PTP) orthologous to human R-PTPs such as PTPRJ/Dep-1 (mutated in epithelial cancers; OMIM:600925); DEP-1 is required, redundantly with LIP-1 and LET-60, and downstream of LIN-12, to promote secondary over primary vulval fate in the P5.p and P7.p lineages; DEP-1 is expressed in P5.p and P7.p lineages, and dep-1 acts cell-autonomously in these lineages; DEP-1 colocalizes with LET-23 in punctae, and binds LET-23 in vitro; DEP-1, with LIP-1, is also required for normal duct cell and excretory pore development; dep-1 mutations are wild-type in isolation, but have vulval phenotypes with added mutations in lin-15, lip-1, or let-60; DEP-1 laterally inhibits secondary vulval fates in parallel with LIN-12/Notch signalling; in primary (P5.p) vulval cells, LET-60/RAS-activated SUR-2 inhibits dep-1 and lin-12 expression; since RNAi of 125 out of 165 predicted C. elegans protein phosphatase genes fails to enhance lip-1 mutations, the LIP-1/DEP-1 interaction is likely to be highly specific.
17	D1025.1	D1025.1	n/a	chrX 14,521,627	contains similarity to Homo sapiens Splice isoform 3 of Q9ULU4 Protein kinase C binding protein 1; ENSEMBL:ENSP00000262975
18	K01A2.3	K01A2.3	n/a	chrII 315,416
19	T19C4.1	T19C4.1	n/a	chrV 11,150,485	contains similarity to Lycopersicon esculentum 36.4 kDa proline-rich protein.; SW:PRF1_LYCES
20	C44C1.1	C44C1.1	n/a	chrX 981,899
21	tag-289	F14F3.3	n/a	chrX 10,523,120	C. elegans TAG-289 protein; contains similarity to Pfam domain PF03062 MBOAT family contains similarity to Interpro domain IPR004299 (Membrane bound O-acyl transferase, MBOAT)
22	C30C11.1	C30C11.1	n/a	chrIII 8,450,050	contains similarity to Pfam domain PF01783 Ribosomal L32p protein family contains similarity to Interpro domain IPR002677 (Ribosomal protein L32p)
23	cdh-9	F59C12.1	n/a	chrX 16,598,558	cdh-9 encodes a member of the cadherin superfamily of transmembrane glycoproteins that mediate homophilic cell-cell adhesion; as loss of CDH-9 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of CDH-9 in C. elegans development and/or behavior is not yet known.
24	fbxa-216	Y47H9C.10	n/a	chrI 11,902,379	C. elegans FBXA-216 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
25	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
26	T10B5.3	T10B5.3	n/a	chrV 1,866,374	contains similarity to Pfam domain PF08162 NUC189 domain contains similarity to Interpro domain IPR012979 (Protein of unknown function NUC189, C-terminal)
27	ceh-41	T26C11.5	n/a	chrX 1,847,671	ceh-41 encodes a a ONECUT class CUT homeobox protein with a single N-terminal OCAM domain; the OCAM domain is a nematode-specific motif conserved between CEH-21, CEH-41, and T02B5.2; ceh-41 is one of three nematode-specific ONECUT genes in a cluster with ceh-21 and ceh-39; ceh-41 has no obvious function in mass RNAi assays.
28	F07A5.3	F07A5.3	n/a	chrI 7,355,830	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
29	F16G10.9	F16G10.9	n/a	chrII 2,385,448	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
30	C34C12.8	C34C12.8	n/a	chrIII 3,460,983	contains similarity to Pfam domain PF01025 GrpE contains similarity to Interpro domains IPR009012 (GrpE nucleotide exchange factor, head), IPR013805 (GrpE nucleotide exchange factor, coiled-coil), IPR000740 (GrpE nucleotide exchange factor)
31	tag-175	D2013.10	n/a	chrII 9,324,253	tag-175 encodes an ortholog of human TMEM41B, whose protein family is ancient (conserved in both animals and plants) but functionally uncharacterized; TAG-175 is broadly expressed (in hypodermis, muscle, neurons, intestine, spermetheca, and vulva); TAG-175 has no known function in vivo, since neither tag-175(RNAi) nor tag-175(gk278) has obvious phenotypes.
32	hog-1	W06B11.4	n/a	chrX 5,852,661	hog-1 encodes a hedgehog-like protein, with a solitary Hint/Hog domain; the function of HOG-1's isolated Hint/Hog domain is unknown; in proteins where they coexist with other, N-terminal, domains, the Hint/Hog domain is predicted to cut its host protein into two halves and then covalently link cholesterol to the C-terminus of the N-terminal domain; HOG-1 is weakly required for normal molting; HOG-1 is also required for normal adult alae formation, growth to full size, cuticle adhesion, and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
33	ZC250.3	ZC250.3	n/a	chrV 5,796,478	contains similarity to Pfam domain PF04142 Nucleotide-sugar transporter contains similarity to Interpro domains IPR004689 (UDP-galactose transporter), IPR007271 (Nucleotide-sugar transporter)
34	phat-2	C46H11.9	n/a	chrI 5,047,210	C. elegans PHAT-2 protein; contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
35	C25A1.4	C25A1.4	n/a	chrI 10,171,209	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
36	K04G2.9	K04G2.9	n/a	chrI 8,056,298	contains similarity to Pfam domain PF01284 Membrane-associating domain contains similarity to Interpro domain IPR008253 (Marvel)
37	BE10.2	BE10.2	n/a	chrIII 12,795,671	contains similarity to Homo sapiens Transmembrane protein 195; ENSEMBL:ENSP00000341662
38	F47B3.3	F47B3.3	n/a	chrI 3,964,844	contains similarity to Pfam domain PF01284 Membrane-associating domain contains similarity to Interpro domain IPR008253 (Marvel)
39	F25G6.2	F25G6.2	n/a	chrV 8,576,005	contains similarity to Homo sapiens Isoform 1 of Symplekin; ENSEMBL:ENSP00000245934
40	F13E6.2	F13E6.2	n/a	chrX 10,671,215	contains similarity to Pfam domain PF05186 Dpy-30 motif contains similarity to Interpro domains IPR000850 (Adenylate kinase), IPR007858 (Dpy-30), IPR011769 (Adenylate/cytidine kinase, N-terminal)
41	F39H12.3	F39H12.3	n/a	chrX 839,898	contains similarity to Pfam domains PF00612 (IQ calmodulin-binding motif) (3), PF02197 (Regulatory subunit of type II PKA R-subunit) contains similarity to Interpro domains IPR003117 (cAMP-dependent protein kinase, regulatory subunit, type I/II alpha/beta), IPR000048 (IQ calmodulin-binding region)
42	glt-6	R05G6.6	n/a	chrIV 7,505,011	glt-6 encodes an ortholog of glutamate/aspartate and neutral amino acid transporters.
43	M03A8.3	M03A8.3	n/a	chrX 6,802,151	n/a
44	ceh-26	K12H4.1	n/a	chrIII 8,069,282	ceh-26 encodes a protein that contains a prospero-related homeodomain; expressed in nuclei of the adult head, tail neurons, and one cell in the postdeirids.
45	mig-2	C35C5.4	n/a	chrX 11,549,321	mig-2 encodes a member of the Rho family of GTP-binding proteins that affects the migration of Q neuroblasts, HSN cells, and CAN cells as well as axon outgrowth and guidance; it is expressed in early embryos and expressed in adults in the vulva, distal tip cells of the gonad, and the sex myoblasts and their descendants.
46	F19C6.3	F19C6.3	n/a	chrX 10,007,249	contains similarity to Pfam domains PF00008 (EGF-like domain) , PF00093 (von Willebrand factor type C domain) contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR008037 (Proteinase inhibitor I19, pacifastin), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR001881 (EGF-like calcium-binding), IPR013032 (EGF-like region, conserved site), IPR001007 (von Willebrand factor, type C)
47	twk-28	C52B9.6	n/a	chrX 4,276,975	C. elegans TWK-28 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
48	F53H4.5	F53H4.5	n/a	chrX 15,883,542	contains similarity to Pfam domain PF01342 SAND domain contains similarity to Interpro domains IPR010919 (SAND-like), IPR000770 (SAND)
49	egl-18	F55A8.1	n/a	chrIV 1,915,415	egl-18 encodes a member of the GATA-family of transcription factors that affects cell migration, cell fate specification; expressed in the head, in hypodermal seam cells, VC neurons, and vulval precursor cells.
50	W04C9.4	W04C9.4	n/a	chrI 462,326