UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F47F2.3	F47F2.3	9.999999999999999e-169	chrX 3,894,817	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
2	adt-1	C02B4.1	n/a	chrX 12,683,974	The adt-1 gene encodes a metalloproteinase with disintegrin-like and metalloproteinase with thrombospondin type I motifs (ADAMTS) that is required for male tail morphogenesis.
3	M05B5.6	M05B5.6	n/a	chrI 7,184,379	contains similarity to Homo sapiens Transient receptor potential cation channel subfamily A member 1; ENSEMBL:ENSP00000262209
4	odr-3	C34D1.3	n/a	chrV 13,248,189	odr-3 encodes a G protein alpha subunit; odr-3 activity is required for normal chemotaxis, odorant avoidance, and nociceptive function as well as cilium morphogenesis in chemosensory neurons; an ODR-3::GFP is expressed in five pairs of sensory neurons AWA, AWB, AWC, ASH, and ADF; the AWC neurons consistently express GFP most strongly, while the AWB neurons express at lower levels and the AWA, ASH, and ADF neurons express only weakly; in AWC neurons, ODR-3::GFP localizes to cilia which have a characteristic wing-shaped morphology.
5	F37C12.1	F37C12.1	n/a	chrIII 7,186,028	contains similarity to Pfam domain PF04502 Family of unknown function (DUF572) contains similarity to Interpro domain IPR007590 (Protein of unknown function DUF572)
6	F40G9.8	F40G9.8	n/a	chrIII 164,235
7	lgc-37	ZC482.5	n/a	chrIII 12,789,021	ZC482.5 is orthologous to the human gene GAMMA-AMINOBUTYRIC ACID A RECEPTOR GAMMA 2 (GABRG2; OMIM:137164), which when mutated leads to disease.
8	str-253	F41B5.8	n/a	chrV 2,253,703	C. elegans STR-253 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR002091 (Aromatic amino acid permease)
9	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
10	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
11	C18A11.2	C18A11.2	n/a	chrX 8,067,797
12	F15A8.1	F15A8.1	n/a	chrX 4,441,526
13	C10E2.2	C10E2.2	n/a	chrX 16,746,897	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
14	Y38H6C.9	Y38H6C.9	n/a	chrV 20,516,299	contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
15	srx-136	F09F3.12	n/a	chrV 13,858,174	C. elegans SRX-136 protein ;
16	eat-4	ZK512.6	n/a	chrIII 9,139,280	eat-4 encodes an ortholog of the mammalian BNPI vesicular glutamate transporter that affects chemotaxis, feeding, foraging and thermotaxis; eat-4 is expressed in specific neurons, including M3L and M3R which are known to be glutamatergic.
17	F35E2.1	F35E2.1	n/a	chrI 11,739,734	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR010601 (Protein of unknown function DUF1182)
18	C17H11.1	C17H11.1	n/a	chrX 8,177,329	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR000276 (GPCR, rhodopsin-like)
19	T20D4.5	T20D4.5	n/a	chrV 3,414,578	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
20	F35C5.11	F35C5.11	n/a	chrII 12,909,598	contains similarity to Mus musculus Lymphocyte antigen Ly-6D precursor (Thymocyte B cell antigen) (ThB).; SW:LY6D_MOUSE
21	mab-5	C08C3.3	n/a	chrIII 7,780,108	mab-5 encodes a homeodomain transcription factor related to the Antennapedia, Ultrabithorax, and abdominal-A family of homeodomain proteins; during postembryonic development, mab-5 is required cell autonomously for specification of posterior cell fates, including hypodermal and neuronal fates, programmed cell deaths, cell proliferation and migration, and fate specification of the male-specific copulatory muscles and sensory rays; in addition, ectopic expression of mab-5 is sufficient to alter cell fates, such as direction of migration or sensory ray identity; in regions of the body where mab-5 expression overlaps with that of lin-39, another C. elegans HOM-C gene, the two genes appear to either compensate for one another's activity or act combinatorially to promote cell fates distinct from those where either gene is expressed alone; a mab-5:lacZ reporter fusion is expressed in cells in the posterior body region from the mid-gastrulation stage of embryogenesis through larval and adult stages; further, antibody staining reveals that MAB-5 expression in the V5 lineage is dynamic, switching on and off several times, while expression in V6 is continuous throughout most of the L1-L3 larval stages; early MAB-5 expression is V6 is dependent upon wild-type activity of pal-1, which encodes the C. elegans Caudal ortholog.
22	T22D1.2	T22D1.2	n/a	chrIV 6,922,337	contains similarity to Interpro domains IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR000694 (Proline-rich region), IPR000480 (Glutelin), IPR013286 (Annexin, type VII)
23	T05B9.2	T05B9.2	n/a	chrII 11,257,607	contains similarity to Rattus norvegicus Fibrillin-2.; TR:Q9WUH9
24	K04F1.7	K04F1.7	n/a	chrV 1,669,148	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
25	sri-20	AC3.1	n/a	chrV 10,369,184	C. elegans SRI-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
26	ZC412.1	ZC412.1	n/a	chrV 14,855,683	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
27	F32B4.5	F32B4.5	n/a	chrI 11,519,244	contains similarity to Homo sapiens BTB/POZ domain-containing protein KCTD16; ENSEMBL:ENSP00000329906
28	ZK816.1	ZK816.1	n/a	chrX 3,359,733
29	K01A6.5	K01A6.5	n/a	chrIV 11,743,140	contains similarity to Homo sapiens Splice isoform 1 of Q14202 Zinc finger protein 261; ENSEMBL:ENSP00000322845
30	C17H1.6	C17H1.6	n/a	chrI 13,131,624	contains similarity to Danio rerio Arginine and glutamate-rich protein 1-B.; SW:Q6P5L7
31	C38H2.2	C38H2.2	n/a	chrIII 10,383,431	C38H2.2 encodes a core 1 UDP-Gal:GalNAcalpha1-Ser/Thr beta1,3-galactosyltransferase (core 1 beta3-Gal-T or T-synthase, EC2.4.1.122); C38H2.2 protein is predicted to be primarily extracellular, with an N-terminal transmembrane domain; C38H2.2 shares 6 conserved cysteine residues with all known T-synthases, and is ubiquitously expressed; enzymatically active C38H2.2 can be generated from insect but not mammalian cells, suggesting that invertebrate-specific chaperones are required for its activity.
32	W04G5.7	W04G5.7	n/a	chrI 11,653,511	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
33	M03E7.4	M03E7.4	n/a	chrV 5,611,266	M03E7.4 encodes a protein, predicted to be secreted, with one chitin-binding peritrophin-A and three low-density lipoprotein receptor domain class A domains; M03E7.4 has no obvious function in mass RNAi assays.
34	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
35	srsx-39	M01B2.9	n/a	chrV 15,255,926	C. elegans SRSX-39 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
36	F41E7.1	F41E7.1	n/a	chrX 10,281,146	contains similarity to Pfam domain PF00999 Sodium/hydrogen exchanger family contains similarity to Interpro domains IPR006153 (Sodium/hydrogen exchanger), IPR001680 (WD40 repeat)
37	T21B6.4	T21B6.4	n/a	chrX 10,934,829	contains similarity to Interpro domain IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
38	rgs-1	C05B5.7	n/a	chrIII 10,015,270	rgs-1 encodes a regulator of G protein signaling; by homology, RGS-1 is predicted to function as a GTPase-activating protein for heterotrimeric G-protein alpha-subunits, and in vitro RGS-1 can stimulate the GTPase activity of purified GOA-1; in vivo, rgs-1 appears to function redundantly with rgs-2 to regulate egg-laying behavior when animals are refed following starvation; rgs-1 is expressed in most or all neurons.
39	F54D12.8	F54D12.8	n/a	chrII 1,396,527	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR003609 (Apple-like)
40	B0546.5	B0546.5	n/a	chrIV 3,389,078	contains similarity to Pfam domain PF06681 Protein of unknown function (DUF1182) contains similarity to Interpro domain IPR010601 (Protein of unknown function DUF1182)
41	T22B2.2	T22B2.2	n/a	chrX 3,922,438
42	npr-3	C10C6.2	n/a	chrIV 11,461,555	C10C6.2 encodes a G-protein-coupled receptor for the FMRFamide-related peptides (FaRPs) encoded by flp-15; C10C6.2 is primarily coupled to Gi/Go proteins, since C10C6.2 signalling is blocked by pertussis toxin; because of its link to Gi/Go proteins, C10C6.2 is expected to be inhibitory
43	F54G2.2	F54G2.2	n/a	chrX 2,636,226	contains similarity to Pfam domain PF00098 Zinc knuckle contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001878 (Zinc finger, CCHC-type)
44	acr-12	R01E6.4	n/a	chrX 13,534,608	acr-12 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit that is a member of the ACR-8-like group of C. elegans nAChR subunits; as an nAChR subunit, ACR-12 is predicted to mediate fast excitatory neurotransmission, however loss of acr-12 activity via mutation or RNAi results in no obvious defects; ACR-12 copurifies with UNC-29 and LEV-1, suggesting that ACR-12 can form receptors with these two non-alpha AChR subunits; an ACR-12::GFP fusion protein is expressed exclusively in ventral cord motor neurons, including the D neurons; in vivo, ACR-12 colocalizes with some, but not all, UNC-38-containing postsynaptic receptor clusters, suggesting that ACR-12 contributes to only a subset of these receptor clusters.
45	F21A10.4	F21A10.4	n/a	chrX 10,185,057	contains similarity to Mus musculus Tumor rejection antigen P815A.; SW:TUR8_MOUSE
46	clec-31	F49A5.2	n/a	chrV 16,857,086	C. elegans CLEC-31 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR003990 (Pancreatitis-associated protein), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
47	srx-2	R03H4.2	n/a	chrV 9,010,093	C. elegans SRX-2 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
48	K02F6.5	K02F6.5	n/a	chrII 2,535,834	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
49	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
50	sru-12	Y45F10B.5	n/a	chrIV 13,583,783	C. elegans SRU-12 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)