UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F47D12.5	F47D12.5	0	chrIII 6,283,998	contains similarity to Homo sapiens Isoform 1 of Protein zyg-11 homolog B; ENSEMBL:ENSP00000294353
2	R06A10.1	R06A10.1	n/a	chrI 1,087,211	contains similarity to Interpro domain IPR016196 (MFS general substrate transporter)
3	col-105	F58F6.2	n/a	chrIV 1,358,519	C. elegans COL-105 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR003979 (Tropoelastin), IPR000694 (Proline-rich region), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	nhr-79	T26H2.9	n/a	chrV 19,209,750	C. elegans NHR-79 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	F08B6.3	F08B6.3	n/a	chrI 6,759,203	contains similarity to Pfam domain PF00036 EF hand contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR008080 (Parvalbumin), IPR000886 (Endoplasmic reticulum, targeting sequence)
7	C23H4.2	C23H4.2	n/a	chrX 12,221,143	contains similarity to Pfam domain PF00135 Carboxylesterase contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR002018 (Carboxylesterase, type B)
8	sdz-18	F45C12.11	n/a	chrII 1,705,740	C. elegans SDZ-18 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
9	fbxb-93	Y63D3A.9	n/a	chrI 14,083,610	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
10	C54E10.6	C54E10.6	n/a	chrV 18,808,334	contains similarity to Saccharomyces cerevisiae Spindle Pole Component of molecular weight 24kDa; SGD:YMR117C
11	T15B7.15	T15B7.15	n/a	chrV 6,837,660	contains similarity to Interpro domain IPR000533 (Tropomyosin)
12	C49A1.5	C49A1.5	n/a	chrI 14,239,274	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
13	dyf-8	C43C3.3	n/a	chrX 9,700,112	dyf-8 encodes a protein predicted to form a cell-surface ligand with a zona pellucida domain; DYF-8 is required for permeability of amphid and phasmid neurons to external dyes, chemotaxis to ammonium chloride, avoidance of high osmotic stimuli, male mating, and dauer formation.
14	ttr-55	F56F4.2	n/a	chrI 6,146,261	C. elegans TTR-55 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
15	sri-71	D2062.3	n/a	chrII 2,628,473	C. elegans SRI-71 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	nhr-157	C17E7.5	n/a	chrV 3,867,765	C. elegans NHR-157 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
17	C08A9.3	C08A9.3	n/a	chrX 17,089,713	contains similarity to Homo sapiens SIDT1 protein; ENSEMBL:ENSP00000377416
18	nhr-127	T13F3.3	n/a	chrV 16,263,066	nhr-127 encodes a member of the nuclear hormone receptor family; expressed in hypodermal seam cells from the embryonic 1.5-fold stage until the L1 larval stage.
19	str-64	T28A11.1	n/a	chrV 3,283,924	C. elegans STR-64 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	let-381	F26B1.7	n/a	chrI 6,322,210	let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult.
21	R03D7.8	R03D7.8	n/a	chrII 10,955,158	contains similarity to Pfam domain PF00149 Calcineurin-like phosphoesterase contains similarity to Interpro domains IPR004843 (Metallophosphoesterase), IPR006186 (Serine/threonine-specific protein phosphatase and bis(5-nucleosyl)-tetraphosphatase)
22	C03B1.3	C03B1.3	n/a	chrX 6,366,380
23	F53B3.5	F53B3.5	n/a	chrX 2,876,207	F53B3.5 encodes a claudin homolog that may regulate ion channels; F53B3.5 is distantly similar to mammalian voltage-dependent calcium channel gamma subunits that are known or suspected to prevent epilepsy in vivo (e.g., stargazin; MGI:1316660); F53B3.5 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
24	fbxb-20	ZC204.9	n/a	chrII 1,649,687	fbxb-20 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-20 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.
25	T05H4.3	T05H4.3	n/a	chrV 6,444,929	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype), IPR003603 (U2A'/phosphoprotein 32 family A, C-terminal)
26	srj-37	F48G7.1	n/a	chrV 639,279	C. elegans SRJ-37 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
27	F26D2.13	F26D2.13	n/a	chrV 16,435,139	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
28	C06E2.2	C06E2.2	n/a	chrX 8,879,967
29	W04H10.2	W04H10.2	n/a	chrII 606,109
30	agr-1	F41G3.12	n/a	chrII 6,767,868	agr-1 encodes a large (1396-residue) putative agrin, orthologous to human AGRIN (OMIM:103320), EGFLAM, and Q9NQ15; AGR-1 is expressed in buccal epithelium and deposited in pharyngeal basal epithelium; AGR-1 is also expressed in IL1 neurons, distal tip cells, and intestine; an AGR-1 fragment can cluster vertebrate dystroglycan in cell culture; agr-1(eg1770) mutations show no obvious phenotype, including levimasole resistance, and do not enhance other mutations perturbing acetylcholine signalling, the dystrophin-glycoprotein-complex, muscle cell differentiation, or the extracellular matrix.
31	ZK1055.3	ZK1055.3	n/a	chrV 6,590,794
32	unc-119	M142.1	n/a	chrIII 10,907,547	unc-119 encodes a novel protein that is highly conserved amongst metazoans; unc-119 activity is required for proper development of the nervous system, including axonal branching and fasciculation, and hence, for normal movement, chemosensation, and feeding; unc-119 is expressed pan-neuronally beginning in the early embryo (~60 cells) and continuing through adulthood; although the molecular function of UNC-119 is not yet known, human UNC119, which can rescue C. elegans unc-119 mutant animals, is reported to function as a receptor-associated activator of signal transduction; thus, UNC-119 may be part of a signal transduction pathway that mediates axonal patterning in response to external developmental cues.
33	ZC204.6	ZC204.6	n/a	chrII 1,644,534
34	T02G5.3	T02G5.3	n/a	chrII 7,094,691
35	egl-26	C23H3.1	n/a	chrII 70,469	egl-26 encodes a protein that contains an H-box and an NC domain that is a member of the LRAT (lecithin retinol acyltransferase) subfamily of the NlpC/P60 superfamily of enzymes; egl-26 activity is required for fertility, egg laying, and vulval development, specifically the connection of the uterus to the vulva mediated by proper morphogenesis of vulF, the most dorsal vulval cell; EGL-26 is an apical membrane protein that is expressed in many cells, including vulF, and appears to be expressed near the vulva and uterus only during the L4 larval stage; EGL-26 membrane localization is necessary for its function.
36	vab-7	M142.4	n/a	chrIII 10,923,070	The vab-7 gene encodes an even-skipped-like homeodomain protein that is required for DB motoneuron identity and posterior DB axonal polarity.
37	F36F12.1	F36F12.1	n/a	chrV 2,101,648	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR008167 (Protein of unknown function DUF23, C-terminal), IPR008166 (Protein of unknown function DUF23)
38	fbxb-115	T26H2.2	n/a	chrV 19,239,099	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
39	sdz-38	ZK892.7	n/a	chrII 9,981,301	C. elegans SDZ-38 protein; contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)
40	AH10.3	AH10.3	n/a	chrV 14,144,698	contains similarity to Tomato yellow leaf curl virus Hypothetical 10.9 kDa protein (C4 protein).; SW:YC4_TYLCU
41	E03H4.11	E03H4.11	n/a	chrI 12,433,962	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
42	R07C3.7	R07C3.7	n/a	chrII 916,765
43	K02F6.7	K02F6.7	n/a	chrII 2,527,240
44	dpy-28	Y39A1B.3	n/a	chrIII 10,770,127	dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1.
45	R07C3.5	R07C3.5	n/a	chrII 931,761
46	fbxa-7	T20H9.1	n/a	chrIII 2,250,698	C. elegans FBXA-7 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
47	F14F4.1	F14F4.1	n/a	chrX 14,926,903	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002286 (P2 purinoceptor), IPR000276 (GPCR, rhodopsin-like), IPR001817 (Vasopressin receptor)
48	fbxb-49	K05F6.1	n/a	chrII 1,570,989	C. elegans FBXB-49 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
49	C05E11.3	C05E11.3	n/a	chrX 4,580,554	contains similarity to Mus musculus Lysosomal-associated transmembrane protein 4A (Golgi 4-transmembranesspanning transporter) (Mouse transporter protein) (MTP).; SW:Q60961
50	ZK1010.8	ZK1010.8	n/a	chrIII 12,998,222	contains similarity to Homo sapiens BRG1-binding protein ELD/OSA1 isoform 1; TR:Q8IZY8