UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	clec-79	F47C12.4	0	chrIV 3,974,525	C. elegans CLEC-79 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR000538 (Link), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
2	T25B9.6	T25B9.6	n/a	chrIV 10,759,435	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
3	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
4	F35H8.1	F35H8.1	n/a	chrII 9,552,878	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILJ6
5	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
6	nspa-1	H12D21.1	n/a	chrV 14,886,813	C. elegans NSPA-1 protein ;
7	C10G11.1	C10G11.1	n/a	chrI 6,307,930
8	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
9	C49H3.3	C49H3.3	n/a	chrIV 7,924,622	contains similarity to Xenopus tropicalis UPF0446 protein C12orf31 homolog.; SW:Q6NVR5
10	F37A8.1	F37A8.1	n/a	chrIII 3,928,769	contains similarity to Rattus norvegicus Myotonic dystrophy kinase-related Cdc42-binding kinase MRCK-beta.; TR:O54875
11	ins-7	ZK1251.2	n/a	chrIV 9,682,219	ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
12	lact-2	ZK945.1	n/a	chrII 10,096,751	lact-2 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
13	F36A4.4	F36A4.4	n/a	chrIV 4,267,908	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
14	F36A4.2	F36A4.2	n/a	chrIV 4,271,510	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
15	msp-32	R05F9.3	n/a	chrII 4,898,889	msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
16	W01B6.6	W01B6.6	n/a	chrIV 10,081,890	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
17	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
18	F35H10.2	F35H10.2	n/a	chrIV 8,329,510
19	B0273.1	B0273.1	n/a	chrIV 5,494,609
20	W02D7.4	W02D7.4	n/a	chrV 8,297,041	contains similarity to Interpro domain IPR016181 (Acyl-CoA N-acyltransferase)
21	ZK666.8	ZK666.8	n/a	chrII 10,492,235	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
22	nspa-8	W06A7.5	n/a	chrV 14,826,947	C. elegans NSPA-8 protein ;
23	ZK1128.3	ZK1128.3	n/a	chrIII 10,117,815	contains similarity to Mus musculus 2410017P07Rik protein.; TR:Q9CZE0
24	gst-9	R05F9.5	n/a	chrII 4,892,523	gst-9 encodes a predicted glutathione S-transferase; by homology, GST-9 is predicted to play a role in the detoxification of environmental toxins and xenobiotics by transferring glutathione to reactive electrophilic compounds; however, as loss of gst-9 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GST-9 in C. elegans development and/or behavior is not yet known.
25	nlp-2	T24D8.5	n/a	chrX 2,344,350	C. elegans NLP-2 protein ;
26	W03D8.9	W03D8.9	n/a	chrI 2,785,349	contains similarity to Pfam domain PF05884 Caenorhabditis elegans protein of unknown function (DUF856) contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR008574 (Protein of unknown function DUF856, Caenorhabditis species)
27	Y6E2A.8	Y6E2A.8	n/a	chrV 15,725,749	contains similarity to Encephalitozoon cuniculi UPF0329 protein ECU05_1680/ECU11_0050.; SW:Q8STA9
28	F47D12.7	F47D12.7	n/a	chrIII 6,294,525	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF00651 (BTB/POZ domain) , PF07646 (Kelch motif) contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000210 (BTB/POZ-like), IPR006652 (Kelch repeat type 1), IPR011333 (BTB/POZ fold), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013069 (BTB/POZ), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
29	nspa-5	ZC412.6	n/a	chrV 14,878,391	C. elegans NSPA-5 protein ;
30	nspa-9	C40H5.1	n/a	chrX 11,739,026	C. elegans NSPA-9 protein ;
31	R13H9.5	R13H9.5	n/a	chrIV 5,066,321	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
32	nspa-3	ZC412.7	n/a	chrV 14,880,465	C. elegans NSPA-3 protein ;
33	ssp-11	T28H11.6	n/a	chrIV 4,999,632	C. elegans SSP-11 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
34	ilys-3	C45G7.3	n/a	chrIV 2,464,939	C. elegans ILYS-3 protein; contains similarity to Pfam domain PF05497 Destabilase contains similarity to Interpro domain IPR008597 (Destabilase)
35	R04B5.11	R04B5.11	n/a	chrV 10,090,998	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000248104
36	Y51A2B.1	Y51A2B.1	n/a	chrV 18,373,264	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR016160 (Aldehyde dehydrogenase, conserved site)
37	K08F4.3	K08F4.3	n/a	chrIV 10,129,732	contains similarity to Pfam domain PF05753 Translocon-associated protein beta (TRAPB) contains similarity to Interpro domain IPR008856 (Translocon-associated beta)
38	ttr-4	F40F12.1	n/a	chrIII 9,916,526	sdz-17 encodes a protein that contains a transthyretin-like domain; SDZ-17 belongs to a family of apparently nematode-specific proteins whose function is not yet known; early zygotic expression of sdz-17 is dependent upon the SKN-1 transcription factor.
39	C09B9.2	C09B9.2	n/a	chrIV 5,030,143
40	T05C12.3	T05C12.3	n/a	chrII 8,172,837	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
41	T28H10.3	T28H10.3	n/a	chrV 12,513,961	contains similarity to Pfam domain PF01650 Peptidase C13 family contains similarity to Interpro domain IPR001096 (Peptidase C13, legumain)
42	msp-74	F09C12.7	n/a	chrII 5,115,201	msp-74 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
43	C06A5.6	C06A5.6	n/a	chrI 5,984,551
44	Y40H7A.10	Y40H7A.10	n/a	chrIV 15,212,835	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
45	hdl-1	ZK829.2	n/a	chrIV 11,947,905	C. elegans HDL-1 protein; contains similarity to Pfam domain PF00282 Pyridoxal-dependent decarboxylase conserved domain contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR010977 (Aromatic-L-amino-acid decarboxylase), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
46	B0207.5	B0207.5	n/a	chrI 5,927,603
47	F09B9.4	F09B9.4	n/a	chrX 10,161,110	contains similarity to Interpro domain IPR003993 (Treacher Collins syndrome, treacle)
48	C36C5.5	C36C5.5	n/a	chrV 3,157,450	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
49	ZK596.2	ZK596.2	n/a	chrIV 10,908,696	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
50	ttr-3	K03H1.3	n/a	chrIII 9,926,034	K03H1.3 encodes a protein containing a predicted signal sequence followed by a transthyretin-like domain; the product of K03H1.3 belongs to a family of apparently nematode-specific proteins whose function is not yet known.