UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	nhr-185	F47C10.1	0	chrV 3,845,862	C. elegans NHR-185 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000306 (Zinc finger, FYVE-type), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
2	snf-6	M01G5.5	n/a	chrIII 1,526,486	snf-6 encodes a member of the sodium:neurotransmitter symporter family.
3	T05A8.6	T05A8.6	n/a	chrII 2,739,156	contains similarity to Xenopus laevis Integumentary mucin C.1 (FIM-C.1) (Fragment).; SW:Q05049
4	T22B2.5	T22B2.5	n/a	chrX 3,910,583
5	R09H3.3	R09H3.3	n/a	chrX 1,667,620
6	ZC132.8	ZC132.8	n/a	chrV 4,316,012
7	C50F4.14	C50F4.14	n/a	chrV 9,548,707	The C50F4.14 gene encodes a putative GDP-fucose transporter orthologous to the human GDP-FUCOSE TRANSPORTER 1 gene (LAD II; OMIM:605881), which when mutated leads to congenital disorder of glycosylation, type IIc.
8	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
9	F55E10.1	F55E10.1	n/a	chrX 8,342,071
10	B0348.2	B0348.2	n/a	chrV 46,173	contains similarity to Interpro domain IPR006629 (LPS-induced tumor necrosis factor alpha factor)
11	ZC477.4	ZC477.4	n/a	chrIV 7,098,647
12	F10D2.8	F10D2.8	n/a	chrV 7,150,438	contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
13	ncx-6	C07A9.4	n/a	chrIII 9,712,021	ncx-6 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-7/-10; NCX-6 may function intracellularly; NCX-6 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-6 has no obvious function in mass RNAi assays.
14	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
15	puf-4	M4.2	n/a	chrIV 3,207,566	C. elegans PUF-4 protein; contains similarity to Pfam domain PF00806 Pumilio-family RNA binding repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR001313 (Pumilio RNA-binding region), IPR016024 (Armadillo-type fold)
16	aqp-7	M02F4.8	n/a	chrX 3,026,113	aqp-7 encodes an aquaglyceroporin whose expression in Xenopus oocytes increases either water or glycerol permeability five- to seven-fold; AQP-7 has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its several paralogs; AQP-7 is expressed in muscle punctae (perhaps focal adhesions).
17	F54D5.11	F54D5.11	n/a	chrII 11,541,574	contains similarity to Pfam domain PF02186 TFIIE beta subunit core domain contains similarity to Interpro domains IPR011991 (Winged helix repressor DNA-binding), IPR016656 (Transcription initiation factor IIE, beta subunit), IPR003166 (Transcription factor TFIIE beta subunit, core)
18	F41C6.4	F41C6.4	n/a	chrX 6,874,202
19	F15E6.5	F15E6.5	n/a	chrIV 4,289,807	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
20	F41C6.2	F41C6.2	n/a	chrX 6,870,966
21	F57G8.7	F57G8.7	n/a	chrV 16,329,811	contains similarity to Antarctic bacterium str 643 Metalloproteinase precursor.; TR:Q9KH34
22	srx-44	T10C6.4	n/a	chrV 16,021,667	C. elegans SRX-44 protein ; contains similarity to Rattus norvegicus Blue-sensitive opsin (BOP) (Blue cone photoreceptor pigment) (Shortswavelength-sensitive cone opsin) (S opsin).; SW:Q63652
23	ncx-3	ZC168.1	n/a	chrIV 10,719,177	ncx-3 encodes a putative 3Na[+]/1Ca[2+] exchanger, orthologous to human SLC8A1-3 and paralogous to NCX-1/-2; NCX-3 is predicted to export free cytoplasmic Ca[2+] with low affinity but high capacity, being complemented by low-capacity/high-affinity Ca[2+] ATPase pumps such as MCA-1/-3; NCX-3 has tandem Calx-alpha and Calx-beta domains predicted to carry out ion transport and regulation; NCX-3 has no obvious function in mass RNAi assays.
24	C18D4.3	C18D4.3	n/a	chrV 17,532,536	contains similarity to Acetobacter diazotrophicus FixX.; TR:Q9FA07
25	K04F1.10	K04F1.10	n/a	chrV 1,663,542	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domains IPR002048 (Calcium-binding EF-hand), IPR000494 (EGF receptor, L domain)
26	C02F4.5	C02F4.5	n/a	chrIV 10,523,762	contains similarity to Rattus norvegicus Collagen type XXVII proalpha 1 chain.; TR:Q80ZF0
27	C41D7.1	C41D7.1	n/a	chrII 357,032
28	Y40B10B.1	Y40B10B.1	n/a	chrV 1,960,770	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
29	sdf-9	Y44A6D.4	n/a	chrV 20,795,100	sdf-9 encodes a protein tyrosine phosphatase, paralogous to EAK-6; sdf-9 acts in parallel to akt-1 to regulate insulin-like signaling and dauer formation and may promote DAF-9 activity by means of steroid hormone signalling; sdf-9 dauer larvae resemble those of daf-9 and daf-12 dauer-constitutive mutants, and these Daf-c mutants are all enhanced by cholesterol deprivation; SDF-9 is expressed in the neuroendocrine XXXL/R cells, where it associates with the plasma membrane; ablation of the XXXL/R cells in wild-type L1 larvae also causes daf-9-like pseudodauer larvae.
30	M03F8.5	M03F8.5	n/a	chrV 5,935,209	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domain IPR004245 (Protein of unknown function DUF229)
31	srt-62	T27C10.2	n/a	chrI 10,900,411	C. elegans SRT-62 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
32	Y17D7B.5	Y17D7B.5	n/a	chrV 18,775,675	contains similarity to Interpro domain IPR006583 (CW)
33	F49C12.4	F49C12.4	n/a	chrIV 9,303,356	contains similarity to Pfam domain PF01482 Domain of unknown function DUF13 contains similarity to Interpro domain IPR002485 (Protein of unknown function DUF13)
34	C14B9.8	C14B9.8	n/a	chrIII 8,142,045	C14B9.8 is orthologous to the human gene PHOSPHORYLASE KINASE, LIVER, ALPHA-2 SUBUNIT (PHKA2; OMIM:306000), which when mutated leads to liver glycogenosis.
35	B0432.9	B0432.9	n/a	chrII 283,160	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
36	F22D3.5	F22D3.5	n/a	chrII 6,938,664
37	gpa-11	C16A11.1	n/a	chrII 4,254,160	gpa-11 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADL and ASH amphid neurons.
38	F39H12.2	F39H12.2	n/a	chrX 832,122	contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like)
39	pqn-11	C09G1.1	n/a	chrX 15,969,125	PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.
40	F56H6.3	F56H6.3	n/a	chrI 12,289,861
41	sru-2	C33A12.13	n/a	chrIV 9,486,898	C. elegans SRU-2 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
42	C29F9.8	C29F9.8	n/a	chrIII 96,559
43	cdc-48.3	K04G2.3	n/a	chrI 8,034,273	C. elegans CDC-48.3 protein; contains similarity to Pfam domains PF07726 (ATPase family associated with various cellular activities (AAA)) , PF00004 (ATPase family associated with various cellular activities (AAA)) , PF07728 (ATPase family associated with various cellular activities (AAA)) contains similarity to Interpro domains IPR003959 (AAA ATPase, core), IPR011704 (ATPase associated with various cellular activities, AAA-5), IPR011703 (ATPase associated with various cellular activities, AAA-3), IPR003960 (AAA ATPase, conserved site), IPR003593 (AAA+ ATPase, core)
44	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
45	srw-133	T05B4.6	n/a	chrV 4,114,016	C. elegans SRW-133 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
46	srx-93	F59B1.3	n/a	chrV 3,620,070	C. elegans SRX-93 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32), IPR001411 (Tetracycline resistance protein, TetB)
47	T01H10.8	T01H10.8	n/a	chrX 12,134,602	T01H10.8 encodes a BEACH domain-containing protein that is orthologous to the mammalian lysosomal trafficking regulator LYST which when mutated leads to Chediak-Higashi syndrome (CHS, OMIM:606897).
48	F11D11.4	F11D11.4	n/a	chrV 18,762,417	contains similarity to Pfam domain PF03409 Protein of unknown function (DUF274) contains similarity to Interpro domain IPR005071 (Protein of unknown function DUF274)
49	M04D8.4	M04D8.4	n/a	chrIII 10,030,454	contains similarity to Clostridium perfringens Hypothetical protein CPE0262.; TR:Q8XNS0
50	clec-165	F38A1.10	n/a	chrIV 1,246,135	C. elegans CLEC-165 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001680 (WD40 repeat), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)