UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F47B7.5	F47B7.5	8e-110	chrX 3,768,291	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
2	F56C3.7	F56C3.7	n/a	chrX 1,370,660
3	srw-124	C44C3.1	n/a	chrV 2,977,215	C. elegans SRW-124 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
4	Y57A10B.6	Y57A10B.6	n/a	chrII 12,391,276	contains similarity to Pfam domain PF07149 Pes-10 contains similarity to Interpro domain IPR009819 (Pes-10)
5	srt-59	C18H7.8	n/a	chrIV 601,062	C. elegans SRT-59 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR007087 (Zinc finger, C2H2-type)
6	old-1	C08H9.5	n/a	chrII 9,867,626	old-1 encodes a receptor protein tyrosine kinase; old-1 activity is required for stress resistance and regulation of adult lifespan: old-1 mRNA expression is upregulated in response to stress and in daf-2 and age-1 mutant backgrounds; likewise, overexpression of old-1 in wild-type animals extends lifespan and increases resistance to heat and UV irradiation; an OLD-1::GFP fusion protein is expressed in the anterior region of worms, in neuronal, hypodermal, and pharyngeal tissues, as well as in the proximal region of the male gonad; expression is visible in young adults and appears to increase as animals age and in response to heat, starvation, or UV irradiation.
7	F20E11.5	F20E11.5	n/a	chrV 17,461,590	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domain IPR005098 (Protein of unknown function DUF281)
8	nhr-268	K06B4.6	n/a	chrV 15,690,903	C. elegans NHR-268 protein
9	F16G10.8	F16G10.8	9.999999999999999e-27	chrII 2,382,692	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
10	F26A1.7	F26A1.7	n/a	chrIII 4,819,598
11	srh-60	W10G11.9	n/a	chrII 3,585,242	C. elegans SRH-60 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
12	C27C7.7	C27C7.7	n/a	chrI 11,422,886	contains similarity to Pfam domain PF07149 Pes-10 contains similarity to Interpro domain IPR009819 (Pes-10)
13	str-38	T23D5.2	n/a	chrV 15,731,518	C. elegans STR-38 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	gcy-23	T26C12.4	n/a	chrIV 3,286,107	gcy-23 encodes a receptor-type guanylyl cyclase that, along with gcy-8 and gcy-18, constitutes a subfamily of guanylyl cyclase genes in C. elegans; gcy-23 functions redundantly with gcy-8 and gcy-18, and upstream of tax-4, to regulate thermotaxis via the AFD thermosensory neurons, although of the three guanylyl cyclases required, genetic analyses suggest that GCY-18 is the primary guanylyl cyclase required; in addition, loss of gcy-23 activity via RNAi results in lifespan extension; GCY-23 is expressed exclusively in the AFD thermosensory neurons, where it localizes to sensory endings.
15	F44G3.10	F44G3.10	n/a	chrV 16,139,209	F44G3.10 encodes a claudin homolog that may be required for normal cohesion of apical junctions in epithelia; F44G3.10 is worm-specific, with obvious homologs only in C. elegans; F44G3.10 has no obvious function in mass RNAi assays; claudins are integral membrane proteins with four transmembrane sequences that are found in mammalian tight junctions (TJs), induce TJs when transgenically expressed in cells normally lacking them, and can mediate the specific conductance of of specific ions (e.g., magnesium or calcium) through TJs while blocking the flow of water.
16	F16G10.14	F16G10.14	4.0000000000000004e-60	chrII 2,398,093	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
17	cnc-5	R09B5.10	n/a	chrV 1,445,607	cnc-5 encodes one of six C. elegans caenacin peptides; CNC-5 is predicted to be a secreted protein that, based upon similarity to CNC-2, -4, and -6, may function as an antimicrobial peptide in the innate immune response.
18	jkk-1	F35C8.3	n/a	chrX 5,370,204	jkk-1 encodes a member of the MAP kinase kinase superfamily that affects synaptic vesicle localization and is required in type-D motor neurons for normal locomotion; can function in the Hog1 MAP kinase pathway I in yeast as an activator of JNK and is expressed in most neurons
19	F02C12.4	F02C12.4	n/a	chrX 13,393,433	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
20	gst-30	ZK546.11	n/a	chrII 4,934,462	C. elegans GST-30 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
21	srv-21	H04M03.8	n/a	chrIV 5,876,704	C. elegans SRV-21 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
22	F22D6.8	F22D6.8	n/a	chrI 7,099,204
23	C18A11.6	C18A11.6	n/a	chrX 8,034,037
24	hot-7	Y48B6A.9	n/a	chrII 14,212,173	hot-7 encodes a predicted membrane-associated protein that is a member of the Ly-6 superfamily of glycosylphosphatidylinositol (GPI)-linked signaling proteins and is homologous to ODR-2, a neuronally expressed protein required for olfaction; as loss of hot-7 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, the precise role of HOT-7 in C. elegans development and/or behavior is not yet known.
25	F37H8.2	F37H8.2	n/a	chrII 11,173,534	contains similarity to Saccharomyces cerevisiae Structural maintenance of chromosomes (SMC) protein; SGD:YOL034W
26	F09F9.3	F09F9.3	n/a	chrX 4,120,310
27	hlh-27	C17C3.10	n/a	chrII 5,540,531	C. elegans HLH-27 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
28	Y56A3A.33	Y56A3A.33	n/a	chrIII 12,001,104	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
29	B0432.1	B0432.1	n/a	chrII 298,462
30	Y66A7A.7	Y66A7A.7	n/a	chrIII 11,629,581	contains similarity to Lactobacillus plantarum Hypothetical protein.; TR:Q88VI8
31	R52.4	R52.4	n/a	chrII 2,107,797
32	srj-6	F31F4.8	n/a	chrV 653,904	C. elegans SRJ-6 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	str-141	F47G9.2	n/a	chrV 11,323,048	C. elegans STR-141 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
34	nhr-150	C06B8.1	n/a	chrV 15,480,433	C. elegans NHR-150 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
35	ZK380.2	ZK380.2	n/a	chrX 1,633,167	contains similarity to Interpro domain IPR011072 (HR1 rho-binding repeat)
36	F10A3.11	F10A3.11	n/a	chrV 16,163,213	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
37	F18H3.1	F18H3.1	n/a	chrX 13,520,521	contains similarity to Pfam domain PF00622 SPRY domain contains similarity to Interpro domains IPR001870 (B302, (SPRY)-like), IPR003877 (SPla/RYanodine receptor SPRY)
38	tba-5	F16D3.1	n/a	chrI 8,355,612	tba-5 encodes one of nine C. elegans alpha tubulins; by homology, TBA-5 is predicted to be a component of microtubules; as loss of tba-5 function via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, TBA-5 likely functions redundantly with other alpha tubulins as a basic component of cellular architecture that may play additional roles in processes such as cell division, cell movement, and intracellular transport.
39	F53F1.6	F53F1.6	n/a	chrV 13,416,842	contains similarity to Aeropyrum pernix Elongation factor 1-beta (EF-1-beta) (aEF-1beta).; SW:EF1B_AERPE
40	sre-40	T05A7.8	n/a	chrII 4,682,734	C. elegans SRE-40 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
41	srz-23	F58E2.9	n/a	chrIV 3,454,195	C. elegans SRZ-23 protein ;
42	C44H4.6	C44H4.6	n/a	chrX 14,597,741	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
43	sre-13	C38C6.4	n/a	chrII 14,635,649	C. elegans SRE-13 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
44	W06G6.12	W06G6.12	n/a	chrV 16,652,565	contains similarity to Methanosarcina mazei Hypothetical protein MM2681.; TR:Q8PTN2
45	F10A3.12	F10A3.12	n/a	chrV 16,164,918	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
46	nas-16	K03B8.1	n/a	chrV 11,392,697	nas-16 encodes an astacin-like metalloprotease.
47	F47G4.6	F47G4.6	n/a	chrI 14,060,105	contains similarity to Pfam domain PF00505 HMG (high mobility group) box contains similarity to Interpro domains IPR000910 (High mobility group box, HMG1/HMG2), IPR009071 (High mobility group box, HMG)
48	C05D9.3	C05D9.3	n/a	chrX 1,114,346	contains similarity to Pfam domain PF07974 EGF-like domain contains similarity to Interpro domains IPR002369 (Integrin beta subunit, N-terminal), IPR001169 (Integrin beta subunit, C-terminal), IPR015812 (Integrin beta subunit), IPR003659 (Plexin/semaphorin/integrin), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
49	hlh-10	ZK682.4	n/a	chrV 9,281,043	C. elegans HLH-10 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
50	clec-195	Y116A8C.21	n/a	chrIV 17,044,558	C. elegans CLEC-195 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)