UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F47B10.5	F47B10.5	4.0000000000000005e-71	chrX 10,889,736	contains similarity to Xenopus laevis D(2) dopamine receptor 1.; SW:D2D1_XENLA
2	mxl-3	F46G10.6	n/a	chrX 13,350,149	C. elegans MXL-3 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding), IPR002418 (Transcription regulator Myc)
3	sru-31	C50C10.4	n/a	chrV 9,817,248	C. elegans SRU-31 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR002229 (Blood group Rhesus C/E and D polypeptide), IPR003839 (Protein of unknown function DUF215)
4	F20D6.5	F20D6.5	n/a	chrV 8,163,572	contains similarity to Pfam domains PF02958 (Domain of unknown function (DUF227)) , PF07914 (Protein of unknown function (DUF1679)) contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR012877 (Protein of unknown function DUF1679, Caenorhabditis species), IPR004119 (Protein of unknown function DUF227), IPR015897 (CHK kinase-like), IPR008266 (Tyrosine protein kinase, active site)
5	F54D12.5	F54D12.5	n/a	chrII 1,370,835	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
6	F35F10.7	F35F10.7	n/a	chrV 3,286,914	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
7	mtl-2	T08G5.10	n/a	chrV 14,018,435	mtl-2 encodes one of two C. elegans metallothioneins, small, cysteine-rich, metal-binding proteins; MTL-2 functions in metal detoxification and homeostasis and stress adaptation; in addition, mtl-2 plays a role in regulating growth and fertility; mtl-2 expression is induced in larval and adult intestinal cells following exposure to cadmium or heat shock; MTL-2 intestinal expression is dependent upon ELT-2, an intestine-specific GATA-type transcription factor; mtl-2 is downregulated by DAF-16 in daf-2 mutants.
8	F25E5.5	F25E5.5	n/a	chrV 7,448,059	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
9	T14B4.5	T14B4.5	n/a	chrII 6,717,303
10	ttm-2	F26G1.4	n/a	chrII 4,765,267	C. elegans TTM-2 protein; contains similarity to Pfam domain PF00339 Arrestin (or S-antigen), N-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011021 (Arrestin-like, N-terminal)
11	let-70	M7.1	n/a	chrIV 11,081,640	let-70 encodes a class I E2 ubiquitin conjugating enzyme; let-70 was identified in screens for essential genes and phenotypic analyses indicate that loss of let-70 activity results in embryonic and larval lethality with defects in sarcomere assembly; purified LET-70 can stimulate the self-ubiquitylation activities of CHN-1 and UFD-2, E4 ubiquitin conjugation factors and, in addition, can stimulate the CHN-1- and UFD-2-dependent multiubiquitylation of UNC-45, a myosin-directed chaperone; in this manner, LET-70 may regulate UNC-45 degradation and myosin assembly; RNA blot analyses and a let-70-lacZ reporter fusion reveal that let-70 is abundantly expressed at all stages of development, including the dauer larval stage; strong staining is observed in most somatic tissues until adult stages, when expression generally becomes restricted to the nervous system.
12	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
13	F59F4.2	F59F4.2	n/a	chrX 15,841,893	contains similarity to Pfam domain PF06624 Ribosome associated membrane protein RAMP4 contains similarity to Interpro domain IPR010580 (Ribosome associated membrane RAMP4)
14	F09G2.1	F09G2.1	n/a	chrV 7,202,915	contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
15	E02H9.2	E02H9.2	n/a	chrIII 2,466,125
16	cyp-13A2	T10B9.7	n/a	chrII 9,785,530	C. elegans CYP-13A2 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002402 (Cytochrome P450, E-class, group II), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
17	F35F10.6	F35F10.6	n/a	chrV 3,288,593	contains similarity to Pfam domain PF06162 Caenorhabditis elegans protein of unknown function (DUF976) contains similarity to Interpro domains IPR010381 (Protein of unknown function DUF976, Caenorhabditis species), IPR016125 (Peptidase C15, pyroglutamyl peptidase I-like)
18	C06E2.1	C06E2.1	n/a	chrX 8,873,724	contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
19	F15B9.6	F15B9.6	n/a	chrV 13,015,372	contains similarity to Interpro domain IPR001211 (Phospholipase A2)
20	hex-1	T14F9.3	n/a	chrX 2,225,047	hex-1 encodes a beta-N-acetylhexosaminidase that is orthologous to the human gene CERVICAL CANCER PROTO-ONCOGENE 7 (HEXB; OMIM:606873), which when mutated leads to disease.
21	hlh-15	C43H6.8	n/a	chrX 2,413,123	C. elegans HLH-15 protein; contains similarity to Pfam domain PF00010 Helix-loop-helix DNA-binding domain contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR011598 (Helix-loop-helix DNA-binding)
22	F59F4.1	F59F4.1	n/a	chrX 15,836,220	contains similarity to Pfam domains PF01756 (Acyl-CoA oxidase) , PF02770 (Acyl-CoA dehydrogenase, middle domain) contains similarity to Interpro domains IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR012258 (Acyl-CoA oxidase), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR002655 (Acyl-CoA oxidase, C-terminal), IPR009075 (Acyl-CoA dehydrogenase/oxidase C-terminal)
23	C54D10.9	C54D10.9	n/a	chrV 12,448,057	contains similarity to Interpro domain IPR001904 (Paxillin)
24	C32H11.11	C32H11.11	n/a	chrIV 12,938,618	contains similarity to Pfam domain PF02520 Domain of unknown function DUF148 contains similarity to Interpro domain IPR003677 (Protein of unknown function DUF148)
25	ZK1290.5	ZK1290.5	n/a	chrII 7,530,168	contains similarity to Pfam domain PF00248 Aldo/keto reductase family contains similarity to Interpro domain IPR001395 (Aldo/keto reductase)
26	F54A5.1	F54A5.1	n/a	chrI 990,926	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR010982 (Lambda repressor-like, DNA-binding), IPR012287 (Homeodomain-related), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
27	F09C12.6	F09C12.6	n/a	chrII 5,117,137	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
28	Y106G6A.1	Y106G6A.1	n/a	chrI 9,937,203	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
29	arx-2	K07C5.1	n/a	chrV 10,336,882	arx-2 encodes the C. elegans ortholog of the Arp2 subunit of the actin-related protein (Arp)2/3 complex.
30	gpa-13	F18E2.5	n/a	chrV 12,753,806	gpa-13 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASH, AWC, PHA, and PHB.
31	ZK1240.2	ZK1240.2	n/a	chrII 2,324,281	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
32	B0507.2	B0507.2	n/a	chrV 8,775,382	contains similarity to Interpro domain IPR004328 (BRO1)
33	spp-8	C28C12.5	n/a	chrIV 8,482,669	C. elegans SPP-8 protein; contains similarity to Pfam domain PF03489 Saposin-like type B, region 2 contains similarity to Interpro domains IPR008138 (Saposin-like type B, 2), IPR011001 (Saposin-like), IPR008139 (Saposin B)
34	R07B1.3	R07B1.3	n/a	chrX 9,859,984	contains similarity to Pfam domain PF01130 CD36 family contains similarity to Interpro domain IPR002159 (CD36 antigen)
35	F59A7.2	F59A7.2	n/a	chrV 2,016,188
36	R11G10.2	R11G10.2	n/a	chrV 13,513,568	contains similarity to Pfam domain PF05694 56kDa selenium binding protein (SBP56) contains similarity to Interpro domain IPR008826 (Selenium-binding protein)
37	F41H10.4	F41H10.4	n/a	chrIV 5,365,559	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DDX5
38	btb-9	F45C12.4	n/a	chrII 1,729,278	C. elegans BTB-9 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
39	C49D10.8	C49D10.8	n/a	chrII 3,859,527	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
40	C46H11.1	C46H11.1	n/a	chrI 5,055,865
41	Y40B1B.5	Y40B1B.5	n/a	chrI 13,436,717	contains similarity to Homo sapiens Retinoblastoma binding protein 6 isoform 1; ENSEMBL:ENSP00000317872
42	F41E6.12	F41E6.12	n/a	chrV 8,627,981
43	C34C12.7	C34C12.7	n/a	chrIII 3,485,435
44	F35H8.2	F35H8.2	n/a	chrII 9,556,425	contains similarity to Pfam domain PF02485 Core-2/I-Branching enzyme contains similarity to Interpro domain IPR003406 (Glycosyl transferase, family 14)
45	ZC196.1	ZC196.1	n/a	chrV 8,744,495
46	plc-3	T01E8.3	n/a	chrII 10,226,078	C. elegans PLC-3 protein; contains similarity to Pfam domains PF07653 (Variant SH3 domain) , PF00168 (C2 domain) , PF00387 (Phosphatidylinositol-specific phospholipase C, Y domain) , PF00018 (SH3 domain) , PF00388 (Phosphatidylinositol-specific phospholipase C, X domain) , PF00017 (SH2 domain) (2)contains similarity to Interpro domains IPR001192 (Phospholipase C, phosphoinositol-specific, C-terminal (PLC)), IPR001849 (Pleckstrin-like), IPR001452 (Src homology-3), IPR011511 (Variant SH3), IPR000909 (Phospholipase C, phosphatidylinositol-specific , X region), IPR008973 (C2 calcium/lipid-binding region, CaLB), IPR001711 (Phospholipase C, phosphatidylinositol-specific, Y domain), IPR016279 (Phosphatidylinositol-4, 5-bisphosphate phosphodiesterase gamma), IPR000980 (SH2 motif), IPR013841 (Phospholipase C, phosphatidylinositol-specific , X and Y boxes), IPR000008 (C2 calcium-dependent membrane targeting)
47	C44C8.4	C44C8.4	n/a	chrIV 891,926	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	B0222.9	B0222.9	n/a	chrV 9,170,672	contains similarity to Pfam domains PF00941 (FAD binding domain in molybdopterin dehydrogenase) , PF02738 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding domain) , PF00111 (2Fe-2S iron-sulfur cluster binding domain) , PF01799 ([2Fe-2S] binding domain) , PF01315 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR001041 (Ferredoxin), IPR002346 (Molybdopterin dehydrogenase, FAD-binding), IPR012675 (Beta-grasp fold, ferredoxin-type), IPR002888 ([2Fe-2S]-binding), IPR016166 (FAD-binding, type 2), IPR006058 (2Fe-2S ferredoxin, iron-sulphur binding site), IPR016169 (CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2), IPR000674 (Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead), IPR008274 (Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding)
49	F35F10.4	F35F10.4	n/a	chrV 3,292,977	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
50	gcy-34	M04G12.3	n/a	chrV 13,384,440	gcy-34 encodes a predicted soluble guanylyl cyclase that is expressed in four candidate sensory neurons connected to the pseudocoelom, URXL, URXR, AQR, and PQR; as loss of gcy-34 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-34 in C. elegans development and/or behavior is not yet known; GCY-34 expression in neurons connected to the pseudocoelom suggests, however, that GCY-34 may play a role in fluid homeostasis.