UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	grd-7	F46H5.6	2e-169	chrX 7,269,472	grd-7 encodes a hedgehog-like protein, with an N-terminal DUF271 domain, a central low-complexity proline-rich domain, and a C-terminal Ground (Grd) domain; GRD-7 is expressed in three to four posterior DA motor neurons of the ventral nerve cord; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-7 is weakly required for normal molting; GRD-7 is also required for normal growth to full size, cuticle adhesion, locomotion, and vulval morphogenesis; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	F09F9.3	F09F9.3	n/a	chrX 4,120,310
5	R106.1	R106.1	n/a	chrX 17,479,990
6	str-220	C42D4.9	n/a	chrIV 7,170,609	str-220 encodes a seven transmembrane chemoreceptor; microarray analyses indicate that str-220 is expressed at higher levels in the AWB olfactory neurons than the AFD thermosensory neurons; anatomical expression studies confirm expression in the AWB neurons; expression of str-220 in AWB is regulated, in part, by the KIN-29 Ser/Thr kinase.
7	C48A7.2	C48A7.2	n/a	chrIV 7,395,373	contains similarity to Pfam domain PF01384 Phosphate transporter family contains similarity to Interpro domains IPR000804 (Clathrin adaptor, sigma subunit/coatomer, zeta subunit), IPR001204 (Phosphate transporter)
8	K09E10.1	K09E10.1	n/a	chrIV 12,306,112	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
9	C46A5.4	C46A5.4	n/a	chrIV 7,752,034	contains similarity to Pfam domain PF03098 Animal haem peroxidase contains similarity to Interpro domains IPR010255 (Haem peroxidase), IPR002007 (Haem peroxidase, animal)
10	Y56A3A.18	Y56A3A.18	n/a	chrIII 11,918,159	Y56A3A.18 encodes an ortholog of S. cerevisiae BUD20 that may suppress tumorous growth in the germline; like PRO-1, -2, and -3, Y56A3A.18 is thought to be required for ribosome biogenesis, suggesting a link between biogenesis in the distal sheath and control of cell division in the germline.
11	W06G6.12	W06G6.12	n/a	chrV 16,652,565	contains similarity to Methanosarcina mazei Hypothetical protein MM2681.; TR:Q8PTN2
12	T05A8.3	T05A8.3	n/a	chrII 2,716,038
13	C05D9.3	C05D9.3	n/a	chrX 1,114,346	contains similarity to Pfam domain PF07974 EGF-like domain contains similarity to Interpro domains IPR002369 (Integrin beta subunit, N-terminal), IPR001169 (Integrin beta subunit, C-terminal), IPR015812 (Integrin beta subunit), IPR003659 (Plexin/semaphorin/integrin), IPR013032 (EGF-like region, conserved site), IPR013111 (EGF, extracellular)
14	W06G6.7	W06G6.7	n/a	chrV 16,640,273	contains similarity to Pfam domains PF00622 (SPRY domain) , PF00041 (Fibronectin type III domain) , PF00097 (Zinc finger, C3HC4 type (RING finger)) , PF00643 (B-box zinc finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR008957 (Fibronectin, type III-like fold), IPR001870 (B302, (SPRY)-like), IPR003961 (Fibronectin, type III), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR003649 (B-box, C-terminal), IPR003877 (SPla/RYanodine receptor SPRY), IPR000315 (Zinc finger, B-box)
15	srh-297	C17F4.4	n/a	chrII 3,229,698	C. elegans SRH-297 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR006084 (DNA repair protein (XPGC)/yeast Rad), IPR003002 (7TM chemoreceptor, subfamily 1)
16	srbc-21	C45H4.7	n/a	chrV 2,156,083	C. elegans SRBC-21 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR001118 (Na+/H+ exchanger, isoform 3 (NHE3))
17	F55C5.6	F55C5.6	n/a	chrV 12,280,460	contains similarity to Pfam domain PF01593 Flavin containing amine oxidoreductase contains similarity to Interpro domains IPR000759 (Adrenodoxin reductase), IPR002937 (Amine oxidase), IPR016040 (NAD(P)-binding)
18	C08B11.3	C08B11.3	n/a	chrII 8,025,126	contains similarity to Pfam domain PF01388 ARID/BRIGHT DNA binding domain contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR016024 (Armadillo-type fold), IPR007087 (Zinc finger, C2H2-type), IPR001606 (AT-rich interaction region)
19	xbx-4	C23H5.3	n/a	chrIV 2,115,124	C. elegans XBX-4 protein ;
20	B0284.3	B0284.3	n/a	chrIII 4,380,175	contains similarity to Interpro domain IPR000215 (Protease inhibitor I4, serpin)
21	set-5	C47E8.8	n/a	chrV 14,702,283	set-5 encodes a large (1,675-residue) protein with an N-terminal SET domain and a C-terminal SPK domain; SET-5 has no non-nematode orthologs, but is paralogous to Y57A10A.1; SET-5's domain organization resembles that of SET-24; neither set-5(ok1568) nor set-5(RNAi) have any obvious phenotypes.
22	srh-272	F37B4.4	n/a	chrV 2,864,166	C. elegans SRH-272 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
23	F48F7.3	F48F7.3	n/a	chrX 13,964,989	contains similarity to Pfam domain PF01762 Galactosyltransferase contains similarity to Interpro domain IPR002659 (Glycosyl transferase, family 31)
24	F21D12.2	F21D12.2	n/a	chrII 7,318,858
25	F46E10.3	F46E10.3	n/a	chrV 6,519,002	contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
26	F35E8.10	F35E8.10	n/a	chrV 15,919,877	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
27	C27C7.7	C27C7.7	n/a	chrI 11,422,886	contains similarity to Pfam domain PF07149 Pes-10 contains similarity to Interpro domain IPR009819 (Pes-10)
28	C18A11.6	C18A11.6	n/a	chrX 8,034,037
29	B0563.1	B0563.1	n/a	chrX 9,171,819
30	T15B7.7	T15B7.7	n/a	chrV 6,824,981	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
31	scl-21	Y43F8B.5	n/a	chrV 19,495,187	C. elegans SCL-21 protein; contains similarity to Pfam domain PF00188 SCP-like extracellular protein contains similarity to Interpro domains IPR014044 (SCP-like extracellular), IPR001283 (Allergen V5/Tpx-1 related)
32	srw-87	F57G8.4	n/a	chrV 16,337,424	C. elegans SRW-87 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
33	F55E10.4	F55E10.4	n/a	chrX 8,327,670
34	T15H9.6	T15H9.6	n/a	chrII 9,608,386	contains similarity to Pfam domains PF04926 (Poly(A) polymerase predicted RNA binding domain) , PF01909 (Nucleotidyltransferase domain) , PF04928 (Poly(A) polymerase central domain) contains similarity to Interpro domains IPR007012 (Poly(A) polymerase, central region), IPR002934 (Nucleotidyltransferase), IPR007010 (Poly(A) polymerase, RNA-binding region), IPR014492 (Poly(A) polymerase), IPR011068 (Nucleotidyltransferase, class I, C-terminal-like)
35	T26A5.4	T26A5.4	n/a	chrIII 6,461,112	contains similarity to Pfam domain PF00534 Glycosyl transferases group 1 contains similarity to Interpro domain IPR001296 (Glycosyl transferase, group 1)
36	srx-48	T26H8.2	n/a	chrV 15,303,024	C. elegans SRX-48 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
37	F47B7.3	F47B7.3	n/a	chrX 3,763,711	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
38	ZC477.7	ZC477.7	n/a	chrIV 7,110,897
39	gcy-2	R134.2	n/a	chrII 9,509,771	gcy-2 encodes a predicted transmembrane guanylyl cyclase; as loss of gcy-2 activity via RNA-mediated interference does not result in any abnormalities, the precise role of GCY-2 in C. elegans development and/or behavior is not yet known; by sequence similarity, however, GCY-2 can be predicted to function in chemosensory signal transduction.
40	sdz-20	F53A2.2	n/a	chrIII 13,335,391	C. elegans SDZ-20 protein
41	C18A11.4	C18A11.4	n/a	chrX 8,046,427	contains similarity to Interpro domain IPR000980 (SH2 motif)
42	M04F3.5	M04F3.5	n/a	chrI 4,775,768	contains similarity to Pfam domain PF08397 IRSp53/MIM homology domain contains similarity to Interpro domain IPR013606 (IRSp53/MIM homology domain (IMD))
43	clec-244	T27C5.7	n/a	chrV 17,414,115	C. elegans CLEC-244 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
44	F21D9.8	F21D9.8	n/a	chrV 19,279,623	contains similarity to Medicago truncatula Pectin methyl-esterase PER precursor (EC 3.1.1.11).; TR:Q9SC90
45	T23G5.3	T23G5.3	n/a	chrIII 9,230,130	contains similarity to Pfam domains PF02214 (K+ channel tetramerisation domain) , PF00786 (P21-Rho-binding domain) contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR000095 (PAK-box/P21-Rho-binding), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
46	C05G5.5	C05G5.5	n/a	chrX 14,758,374	contains similarity to Homo sapiens hypothetical protein; ENSEMBL:ENSP00000360931
47	Y66A7A.7	Y66A7A.7	n/a	chrIII 11,629,581	contains similarity to Lactobacillus plantarum Hypothetical protein.; TR:Q88VI8
48	C17H1.5	C17H1.5	n/a	chrI 13,115,023	contains similarity to Mus musculus Inner centromere protein.; SW:Q9WU62
49	R155.4	R155.4	n/a	chrIII 1,978,876	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domains IPR008967 (p53-like transcription factor, DNA-binding), IPR003125 (Protein of unknown function WSN), IPR005427 (Salmonella/Shigella invasin protein C)
50	Y113G7A.14	Y113G7A.14	n/a	chrV 20,132,595	contains similarity to Lumpy skin disease virus LSDV134 variola virus B22R-like protein.; TR:Q91MN0