UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ape-1	F46F3.4	0	chrV 11,680,585	ape-1 encodes an ortholog of inhibitory p53-interacting protein (iASPP); APE-1 binds CEP-1 in vitro, and shares 38% amino-acid identity in its ankyrin repeats and SH3 domain to iASPP, with many iASPP residues contacting p53 being conserved; RNAi of ape-1 induces CEP-1- and HUS-1-dependent apoptosis in the germline, consistent with inhibition of the CEP-1/HUS-1 DNA damage checkpoint by APE-1 in the germline; excess ape-1(RNAi) apoptosis also requires CED-3.
2	ZK218.1	ZK218.1	n/a	chrV 17,092,954	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
3	tag-322	C33H5.10	n/a	chrIV 7,784,751	C. elegans TAG-322 protein ; contains similarity to Drosophila melanogaster Flybase gene name is CG5913-PA;; FLYBASE:CG5913
4	dhs-19	T11F9.11	n/a	chrV 11,489,664	dhs-19 encodes a short-chain dehydrogenase predicted to be mitochondrial.
5	Y75B8A.7	Y75B8A.7	n/a	chrIII 12,156,145	contains similarity to Pfam domain PF04006 Mpp10 protein contains similarity to Interpro domains IPR012173 (U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p), IPR007151 (Mpp10 protein)
6	F10C2.5	F10C2.5	n/a	chrV 12,047,001	contains similarity to Pfam domain PF01532 Glycosyl hydrolase family 47 contains similarity to Interpro domains IPR010916 (TonB box, conserved site), IPR001382 (Glycoside hydrolase, family 47)
7	F19D8.2	F19D8.2	n/a	chrX 13,835,397	contains similarity to Homo sapiens Splice isoform 1 of Q9UMN6 Myeloid/lymphoid or mixed-lineage leukemia protein 4; ENSEMBL:ENSP00000222270
8	emb-30	F54C8.3	n/a	chrIII 9,438,172	emb-30 encodes an anaphase-promoting complex/cyclosome (APC/C) component orthologous to mammalian APC-4 and Schizosaccharomyces pombe Lid1; EMB-30 is required for the metaphase-to-anaphase transition during meiosis and mitosis, for establishing anterior-posterior polarity in the early embryo, and for proper localization of germline granules and the maternally provided PAR-2 and PAR-3 proteins.
9	B0212.3	B0212.3	n/a	chrIV 3,541,891	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domains IPR006570 (SPK), IPR001202 (WW/Rsp5/WWP)
10	B0035.16	B0035.16	n/a	chrIV 11,295,988	contains similarity to Pfam domain PF03054 tRNA methyl transferase contains similarity to Interpro domains IPR014729 (Rossmann-like alpha/beta/alpha sandwich fold), IPR004506 (tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase)
11	Y53C12A.3	Y53C12A.3	n/a	chrII 9,705,022	contains similarity to Pfam domains PF03942 (DTW domain) , PF04893 (Yip1 domain) contains similarity to Interpro domains IPR006977 (Yip1 domain), IPR005636 (DTW)
12	tag-348	T04H1.1	n/a	chrV 12,237,724	C. elegans TAG-348 protein; contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
13	hum-1	F29D10.4	0.004	chrI 8,848,443	hum-1 encodes a class I unconventional myosin heavy chain that, within this class, is most closely related to the amoeboid myosin I subclass; loss of hum-1 activity via RNAi results in a low frequency of aldicarb resistance, suggesting that hum-1 may play a role in regulating synapse structure and/or function; when expressed in the DA cholinergic motor neurons, a HUM-1 reporter fusion protein localizes solely to punctate structures.
14	grd-10	F09D12.1	n/a	chrIV 3,441,427	grd-10 encodes a hedgehog-like protein, with an N-terminal signal sequence and a C-terminal Ground domain; GRD-10 is expressed in seam cells; the Ground domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; GRD-10 is weakly required for normal molting; GRD-10 is also required for normal growth to full size and locomotion; all of these requirements may reflect common defects in cholesterol-dependent hedgehog-like signalling or in vesicle trafficking.
15	C50F4.14	C50F4.14	n/a	chrV 9,548,707	The C50F4.14 gene encodes a putative GDP-fucose transporter orthologous to the human GDP-FUCOSE TRANSPORTER 1 gene (LAD II; OMIM:605881), which when mutated leads to congenital disorder of glycosylation, type IIc.
16	F48G7.4	F48G7.4	n/a	chrV 620,860
17	F20B4.2	F20B4.2	n/a	chrX 17,704,274
18	T01D3.2	T01D3.2	n/a	chrV 13,706,650	contains similarity to Pfam domain PF00989 PAS fold contains similarity to Interpro domains IPR001092 (Basic helix-loop-helix dimerisation region bHLH), IPR013767 (PAS fold), IPR000014 (PAS), IPR011598 (Helix-loop-helix DNA-binding), IPR001067 (Nuclear translocator)
19	T12E12.3	T12E12.3	n/a	chrIV 5,543,170
20	C04G6.4	C04G6.4	n/a	chrII 5,082,452	contains similarity to Interpro domain IPR000694 (Proline-rich region)
21	spat-1	F57C2.6	n/a	chrII 14,531,337	spat-1 encodes a divergent ortholog of Drosophila melanogaster AURORA BOREALIS (BORA) and human BORA (OMIM:610510); SPAT-1 is specifically required for PAR protein-dependent cell-polarity; RNAi of spat-1 weakly suppresses the embryonic lethality of par-2(it5ts) at restrictive temperature.
22	sru-2	C33A12.13	n/a	chrIV 9,486,898	C. elegans SRU-2 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
23	W06A11.1	W06A11.1	n/a	chrII 4,068,658
24	atg-16.1	F02E8.5	n/a	chrX 4,461,104	atg-16.1 encodes a divergent ortholog of the autophagic budding yeast protein Atg16p, and of human ATG16L1 (OMIM:610767, associated with Crohn disease) and ATG16L2; ATG-16.1 is paralogous to ATG-16.2; ATG-16.1 is expressed in larval and adult intestine, renal gland cells, stomato-intestinal muscle, anal depressor muscle, and head mesodermal cell; ATG-16.1 has no obvious function in mass RNAi assays.
25	F12A10.1	F12A10.1	n/a	chrII 5,497,839	contains similarity to Oryza sativa subsp indica Putative uncharacterized protein.; TR:A2YC95
26	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
27	sel-12	F35H12.3	n/a	chrX 917,054	sel-12 encodes a transmembrane domain protein orthologous to presenilins; during gonadal, germline, and vulval development, sel-12 functions, within receiving cells, to positively regulate lin-12 and glp-1 Notch-like signaling pathways; sel-12 presenilin activity and/or levels are likely regulated by the SET/NAP protein sub-family member encoded by spr-2, as mutations in sel-12 are suppressed by mutations in spr-2; spr-2 regulation of sel-12 occurs in a hop-1 presenilin dependent manner.
28	Y62H9A.11	Y62H9A.11	n/a	chrX 11,906,196
29	srh-17	C47E8.2	n/a	chrV 14,662,094	C. elegans SRH-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	D1007.8	D1007.8	n/a	chrI 4,604,894	contains similarity to Interpro domains IPR016027 (Nucleic acid-binding, OB-fold-like), IPR012340 (Nucleic acid-binding, OB-fold)
31	W04G3.2	W04G3.2	n/a	chrX 11,063,262	contains similarity to Saccharomyces cerevisiae Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes; SGD:YGR097W
32	W04G5.5	W04G5.5	n/a	chrI 11,635,717	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
33	F54B11.10	F54B11.10	n/a	chrX 13,582,322	contains similarity to Conus arenatus Conotoxin scaffold VI/VII.; TR:Q9BP99
34	lgc-7	Y57G11C.2	n/a	chrIV 14,712,127	C. elegans LGC-7 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
35	srx-38	C03A7.5	n/a	chrV 5,154,771	C. elegans SRX-38 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR013305 (ABC transporter, ABCB2), IPR000276 (GPCR, rhodopsin-like)
36	C35D10.1	C35D10.1	n/a	chrIII 4,880,584	contains similarity to Interpro domain IPR013784 (Carbohydrate-binding-like fold)
37	srt-7	C50H11.4	n/a	chrV 3,082,398	C. elegans SRT-7 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000408 (Regulator of chromosome condensation, RCC1)
38	pqn-11	C09G1.1	n/a	chrX 15,969,125	PQN-11 encodes an unfamiliar protein with a glutamine/asparagine-rich domain that is dispensable for viability and gross morphology.
39	str-112	F10D2.4	n/a	chrV 7,137,353	C. elegans STR-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	D2092.5	D2092.5	n/a	chrI 6,603,752	contains similarity to Interpro domains IPR002713 (FF), IPR000533 (Tropomyosin)
41	srd-17	Y2H9A.2	n/a	chrV 13,431,663	C. elegans SRD-17 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
42	srt-13	ZC142.1	n/a	chrV 4,249,044	C. elegans SRT-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000539 (Frizzled protein)
43	clec-165	F38A1.10	n/a	chrIV 1,246,135	C. elegans CLEC-165 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001680 (WD40 repeat), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
44	F09G2.2	F09G2.2	n/a	chrV 7,197,657	contains similarity to Interpro domain IPR011028 (Cyclin-like)
45	fbxa-149	Y38H6C.10	n/a	chrV 20,512,556	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
46	F54D12.1	F54D12.1	n/a	chrII 1,400,894	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
47	M03F4.4	M03F4.4	n/a	chrX 4,957,667
48	R107.2	R107.2	n/a	chrIII 9,044,850	contains similarity to Pfam domain PF01256 Carbohydrate kinase contains similarity to Interpro domain IPR000631 (Carbohydrate kinase)
49	F42A6.6	F42A6.6	n/a	chrIV 3,336,420	contains similarity to Pfam domain PF05603 Protein of unknown function (DUF775) contains similarity to Interpro domain IPR008493 (Protein of unknown function DUF775)
50	lips-12	T13B5.6	n/a	chrII 1,113,234	C. elegans LIPS-12 protein; contains similarity to Pfam domain PF01674 Lipase (class 2) contains similarity to Interpro domain IPR002918 (Lipase, class 2)