UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	tag-83	F46F11.3	2e-143	chrI 5,602,718	C. elegans TAG-83 protein ; contains similarity to Homo sapiens TNS1 protein; ENSEMBL:ENSP00000308321
2	F52E1.9	F52E1.9	n/a	chrV 8,398,736	contains similarity to Interpro domain IPR011332 (Ribosomal protein, zinc-binding)
3	K10D2.4	K10D2.4	n/a	chrIII 5,173,569
4	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
5	srh-269	T03E6.5	n/a	chrV 16,591,043	C. elegans SRH-269 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
6	B0495.6	B0495.6	n/a	chrII 7,698,778	contains similarity to Pfam domain PF07189 Splicing factor 3B subunit 10 (SF3b10) contains similarity to Interpro domain IPR009846 (Splicing factor 3B subunit 5/RDS3 complex subunit 10)
7	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
8	F45F2.7	F45F2.7	n/a	chrV 8,523,135	contains similarity to Pfam domain PF03189 Protein of unknown function, DUF270 contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR004878 (Protein of unknown function DUF270), IPR016196 (MFS general substrate transporter)
9	lis-1	T03F6.5	n/a	chrIII 13,373,822	lis-1 encodes an ortholog of human LIS1, which when mutated leads to lissencephaly (OMIM:247200); it also encodes an ortholog of the Aspergillus nidulans nudF, which mediates nuclear migration along Aspergillus hyphae.
10	srj-40	F38H12.2	n/a	chrV 4,102,865	C. elegans SRJ-40 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
11	srv-8	F53F1.7	n/a	chrV 13,419,959	C. elegans SRV-8 protein; contains similarity to Interpro domains IPR002456 (GPCR, family 3, gamma-aminobutyric acid receptor, type B1), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)
12	F54E4.4	F54E4.4	n/a	chrX 14,643,359	contains similarity to Pfam domain PF03931 Skp1 family, tetramerisation domain contains similarity to Interpro domains IPR001232 (SKP1 component), IPR011333 (BTB/POZ fold), IPR016073 (SKP1 component, POZ)
13	nhr-230	Y17D7A.1	n/a	chrV 18,849,704	C. elegans NHR-230 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
14	F40E3.6	F40E3.6	n/a	chrI 2,651,225
15	gpa-4	T07A9.7	n/a	chrIV 403,531	gpa-4 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ASI.
16	C11D2.2	C11D2.2	n/a	chrIV 6,187,162	contains similarity to Pfam domain PF00026 Eukaryotic aspartyl protease contains similarity to Interpro domains IPR009007 (Peptidase aspartic, catalytic), IPR001969 (Peptidase aspartic, active site), IPR001461 (Peptidase A1)
17	fbxa-112	Y102A5C.13	n/a	chrV 16,947,523	C. elegans FBXA-112 protein; contains similarity to Pfam domain PF01827 FTH domain contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
18	F48C5.1	F48C5.1	n/a	chrX 11,445,448	contains similarity to Pfam domain PF00047 Immunoglobulin domain contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000742 (EGF-like, type 3), IPR007110 (Immunoglobulin-like), IPR013032 (EGF-like region, conserved site), IPR013151 (Immunoglobulin)
19	F55E10.5	F55E10.5	n/a	chrX 8,335,538
20	ifta-1	C54G7.4	n/a	chrX 5,549,123	C. elegans IFTA-1 protein; contains similarity to Pfam domain PF00400 WD domain, G-beta repeat contains similarity to Interpro domains IPR011046 (WD40 repeat-like), IPR017233 (WD repeat protein 35), IPR001680 (WD40 repeat), IPR015943 (WD40/YVTN repeat-like), IPR011011 (Zinc finger, FYVE/PHD-type)
21	srt-5	C50H11.14	n/a	chrV 3,080,169	C. elegans SRT-5 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	C30H6.9	C30H6.9	n/a	chrIV 17,379,717	contains similarity to Bacillus anthracis Hypothetical protein.; TR:Q81PV8
23	C18G1.7	C18G1.7	n/a	chrV 4,746,815	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR008166 (Protein of unknown function DUF23)
24	trx-2	B0024.9	n/a	chrV 10,314,942	C. elegans TRX-2 protein; contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR012335 (Thioredoxin fold), IPR015467 (Thioredoxin family), IPR001200 (Phosducin), IPR013766 (Thioredoxin domain), IPR006662 (Thioredoxin-related), IPR012336 (Thioredoxin-like fold)
25	tsp-11	B0563.2	n/a	chrX 9,164,502	C. elegans TSP-11 protein; contains similarity to Pfam domain PF00335 Tetraspanin family contains similarity to Interpro domains IPR000301 (CD9/CD37/CD63 antigen), IPR008952 (Tetraspanin)
26	F09D1.1	F09D1.1	n/a	chrII 2,570,590	contains similarity to Pfam domains PF00443 (Ubiquitin carboxyl-terminal hydrolase) , PF02148 (Zn-finger in ubiquitin-hydrolases and other protein) contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR001607 (Zinc finger, UBP-type)
27	srx-133	F09F3.4	n/a	chrV 13,849,303	C. elegans SRX-133 protein ;
28	D1007.9	D1007.9	n/a	chrI 4,591,009
29	srh-136	F36D3.6	n/a	chrV 16,496,767	C. elegans SRH-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
30	fbxa-100	F14H3.7	n/a	chrV 16,060,910	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
31	W10G11.4	W10G11.4	n/a	chrII 3,563,054	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domains IPR016638 (Uncharacterised conserved protein UPF0376), IPR002542 (Protein of unknown function DUF19)
32	taf-9	T12D8.7	n/a	chrIII 13,624,992	C. elegans TAF-9 protein; contains similarity to Pfam domain PF02291 Transcription initiation factor IID, 31kD subunit contains similarity to Interpro domains IPR003162 (Transcription factor TAFII-31), IPR009072 (Histone-fold)
33	ceh-24	F55B12.1	n/a	chrV 13,814,273	ceh-24 is orthologous to the human gene SIMILAR TO THYROID TRANSCRIPTION FACTOR 1 (TITF1; OMIM:600635), which when mutated leads to disease.
34	pmp-3	C54G10.3	n/a	chrV 14,650,313	pmp-3 encodes a putative ABC transporter orthologous to human ABCD4 (OMIM:603214) and paralogous to PMP-5; pmp-3 expression levels are unusually stable, with relatively little variation between adults, dauers, and L3 larvae, or between wild-type and daf-2(e1370ts) or daf-16(m26) mutant adults; PMP-3 has no obvious function in mass RNAi assays, and pmp-3(ok1087) mutants are at least grossly normal (in particular, they show no defects in the uptake stage of RNAi).
35	C28A5.5	C28A5.5	n/a	chrIII 4,451,510	contains similarity to Petunia hybrida PGPS/D8.; TR:Q9ZTN1
36	clec-245	C31G12.2	n/a	chrV 18,187,150	C. elegans CLEC-245 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
37	srx-120	F49C5.2	n/a	chrII 12,532,032	C. elegans SRX-120 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
38	T10G3.4	T10G3.4	n/a	chrV 13,483,233	contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
39	glb-12	C52A11.2	n/a	chrII 10,730,655	glb-12 encodes a globin; glb-12 transcription is higher in L3 and dauers than in young adults; in mass RNAi assays, glb-12 is required for embryonic viability, larval growth, and normal body shape, locomotion, and egg laying.
40	C01C4.2	C01C4.2	n/a	chrX 3,717,428
41	K03D7.9	K03D7.9	n/a	chrV 17,488,056	contains similarity to Homo sapiens Olfactory receptor 1A1; ENSEMBL:ENSP00000305207
42	T23F6.2	T23F6.2	n/a	chrIV 12,722,330
43	sru-47	F36D1.3	n/a	chrI 11,290,448	C. elegans SRU-47 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domains IPR015964 (Cytochrome C oxidase subunit II-like, transmembrane region), IPR003839 (Protein of unknown function DUF215)
44	F38A1.13	F38A1.13	n/a	chrIV 1,265,538
45	C49A9.7	C49A9.7	n/a	chrIV 6,203,875	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR001681 (Neurokinin receptor), IPR005395 (Neuropeptide FF receptor), IPR005384 (Duffy antigen/chemokine receptor), IPR000611 (Neuropeptide Y receptor), IPR000276 (GPCR, rhodopsin-like)
46	F59E12.8	F59E12.8	n/a	chrII 5,635,699	contains similarity to Interpro domain IPR015683 (Glutamate receptor-related)
47	Y56A3A.11	Y56A3A.11	n/a	chrIII 11,896,407	contains similarity to Pfam domain PF01974 tRNA intron endonuclease, catalytic C-terminal domain contains similarity to Interpro domains IPR006677 (tRNA intron endonuclease, catalytic domain-like), IPR011856 (Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)
48	Y38H6C.14	Y38H6C.14	n/a	chrV 20,527,484	contains similarity to Leishmania major strain Friedlin Proteophosphoglycan 5.; TR:Q4FX62
49	R05H10.5	R05H10.5	n/a	chrII 14,868,296	contains similarity to Pfam domain PF00255 Glutathione peroxidase contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR000889 (Glutathione peroxidase)
50	F42G8.5	F42G8.5	n/a	chrIV 8,137,753