UCSC C. elegans Gene Sorter

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

UCSC C. elegans Gene Sorter

genome assembly search

sort by display output

#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	pek-1	F46C3.1	0	chrX 11,412,423	pek-1 encodes a predicted transmembrane protein kinase orthologous to human eukaryotic translation initiation factor 2-alpha kinase 3 (EIF2AK3, OMIM:604032), which when mutated leads to Wolcott-Rallison syndrome; PEK-1 is strongly expressed in intestinal cells and is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); PEK-1 may function in the endoplasmic reticulum to phosphorylate eIF2alpha and inhibit protein synthesis in response to endogenous ER stress.
2	R09B5.11	R09B5.11	n/a	chrV 1,440,531	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR003663 (Sugar transporter), IPR016196 (MFS general substrate transporter)
3	F25E5.2	F25E5.2	n/a	chrV 7,456,619	contains similarity to Pfam domain PF04590 Protein of unknown function, DUF595 contains similarity to Interpro domain IPR007669 (Protein of unknown function DUF595)
4	psa-1	Y113G7B.23	n/a	chrV 20,239,752	psa-1 encodes an ortholog of SWI3, a component of the SWI/SNF complex that is conserved from yeast to mammals and that is involved in chromatin remodeling; psa-1 is probably required during mitosis of the T cells for asymmetric cell division, and in addition, is required for embryonic and larval development, as well as normal levels of fertility; psa-1 exhibits strong genetic interactions with lin-35/Rb, as psa-1 larval lethality and sterility at 20 degrees C are greatly enhanced in lin-35;psa-1 double mutants.
5	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
6	F47A4.5	F47A4.5	n/a	chrX 9,835,643	contains similarity to Pfam domains PF01734 (Patatin-like phospholipase) , PF00023 (Ankyrin repeat) (5)contains similarity to Interpro domains IPR016035 (Acyl transferase/acyl hydrolase/lysophospholipase), IPR001638 (Bacterial extracellular solute-binding protein, family 3), IPR002641 (Patatin), IPR002110 (Ankyrin), IPR001680 (WD40 repeat)
7	frm-3	H05G16.1	n/a	chrX 11,578,915	frm-3 encodes a protein containing a FERM domain (Band 4.1 family); expressed in a few cells in the head.
8	W04H10.1	W04H10.1	n/a	chrII 609,207
9	F57G12.2	F57G12.2	n/a	chrX 12,158,178	contains similarity to Mus musculus Nuclear protein ZAP3.; SW:ZAP3_MOUSE
10	ZK1240.1	ZK1240.1	n/a	chrII 2,330,574	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000315 (Zinc finger, B-box)
11	cyp-33C9	C50H11.15	n/a	chrV 3,093,157	C. elegans CYP-33C9 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
12	C54G4.2	C54G4.2	n/a	chrI 8,007,875	contains similarity to Saccharomyces cerevisiae protein of unknown function; SGD:YNR051C
13	ZC416.4	ZC416.4	0.0000000006	chrIV 3,607,952	n/a
14	C34G6.1	C34G6.1	n/a	chrI 5,912,249	contains similarity to Pfam domain PF02985 HEAT repeat contains similarity to Interpro domains IPR011989 (Armadillo-like helical), IPR000357 (HEAT), IPR016024 (Armadillo-type fold)
15	ptr-19	Y39A1B.2	n/a	chrIII 10,786,410	ptr-19 encodes an ortholog of Drosophila and human PTCHD3, which defines one of seven paralogous families of sterol sensing domain (SSD) proteins; PTR-19 is required for normal development in mass RNAi assays; PTR-19 is expressed in pharynx, hypodermis, nervous system (including head neurons), and other cells.
16	F17H10.1	F17H10.1	n/a	chrX 13,106,728	contains similarity to Danio rerio Protein SERAC1.; SW:Q5SNQ7
17	R10D12.8	R10D12.8	n/a	chrV 13,951,956	contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
18	F14B8.6	F14B8.6	n/a	chrX 6,930,764
19	T12B3.1	T12B3.1	n/a	chrIV 7,383,567	contains similarity to Pfam domains PF00782 (Dual specificity phosphatase, catalytic domain) , PF00102 (Protein-tyrosine phosphatase) contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity), IPR000923 (Blue (type 1) copper domain)
20	K08C9.6	K08C9.6	n/a	chrI 11,499,274	contains similarity to Archaeoglobus fulgidus Hypothetical protein AF0327.; TR:O29920
21	C04F6.2	C04F6.2	n/a	chrX 3,397,298
22	F02D8.1	F02D8.1	n/a	chrV 14,975,819	contains similarity to Rattus norvegicus P27 KIP1.; TR:O08769
23	lgc-54	T15B7.16	n/a	chrV 6,841,721	C. elegans LGC-54 protein; contains similarity to Pfam domains PF02931 (Neurotransmitter-gated ion-channel ligand binding domain) , PF02932 (Neurotransmitter-gated ion-channel transmembrane region) contains similarity to Interpro domains IPR006028 (Gamma-aminobutyric acid A receptor), IPR006201 (Neurotransmitter-gated ion-channel), IPR006202 (Neurotransmitter-gated ion-channel ligand-binding), IPR006029 (Neurotransmitter-gated ion-channel transmembrane region)
24	egl-23	Y37A1B.11	n/a	chrIV 14,007,827	egl-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; egl-23 was originally defined by gain-of-function mutations that result in defects in locomotion, egg-laying, and enteric muscle activation; loss of egl-23 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that EGL-23 may function redundantly with other TWK channels; egl-23 does not, however, interact genetically with the UNC-93 group of TWKs encoded by unc-93, sup-9, and sup-10; the EGL-23 expression pattern is not yet known.
25	ZC374.2	ZC374.2	n/a	chrX 10,041,531	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III)
26	F47G6.2	F47G6.2	n/a	chrI 1,475,611	contains similarity to Pfam domain PF00501 AMP-binding enzyme contains similarity to Interpro domain IPR000873 (AMP-dependent synthetase and ligase)
27	F34D10.6	F34D10.6	n/a	chrIII 3,756,086	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
28	unc-38	F21F3.5	n/a	chrI 4,899,335	unc-38 encodes a nicotinic acetylcholine receptor (nAChR) alpha subunit; UNC-38 is required for normal locomotion and egg-laying, and functions as a subunit of a ligand-gated ion channel that likely mediates fast actions of acetylcholine at neuromuscular junctions and in the nervous system; when coexpressed with ACR-2, ACR-3, UNC-29, and LEV-1, non-alpha nAChR subunits, the resulting multimer can form levamisole-gated channels; UNC-38 is expressed postsynaptically in muscles and neurons where it colocalizes with TAX-6, and with ACR-8, ACR-12, and UNC-29, respectively.
29	T10E9.9	T10E9.9	n/a	chrI 6,547,634	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF02771 (Acyl-CoA dehydrogenase, N-terminal domain) contains similarity to Interpro domains IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR006089 (Acyl-CoA dehydrogenase, conserved site), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR006092 (Acyl-CoA dehydrogenase, N-terminal)
30	C37C3.11	C37C3.11	n/a	chrV 7,864,144
31	kin-21	W08D2.8	0.000004	chrIV 9,833,852	C. elegans KIN-21 protein; contains similarity to Pfam domains PF07714 (Protein tyrosine kinase) , PF00069 (Protein kinase domain) , PF00017 (SH2 domain) contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR000980 (SH2 motif), IPR008266 (Tyrosine protein kinase, active site)
32	ndx-1	T26E3.2	n/a	chrI 12,680,484	The ndx-1 gene encodes a NUDIX hydrolase.
33	C50F7.9	C50F7.9	n/a	chrIV 7,731,347
34	col-64	F52F12.2	n/a	chrI 9,894,637	C. elegans COL-64 protein; contains similarity to Pfam domains PF01484 (Nematode cuticle collagen N-terminal domain) , PF01391 (Collagen triple helix repeat (20 copies)) (2)contains similarity to Interpro domains IPR002486 (Nematode cuticle collagen, N-terminal), IPR008161 (Collagen helix repeat), IPR008160 (Collagen triple helix repeat)
35	F35H10.3	F35H10.3	n/a	chrIV 8,326,450
36	T21H3.4	T21H3.4	n/a	chrV 1,144,046	contains similarity to Pfam domain PF00100 Zona pellucida-like domain contains similarity to Interpro domain IPR001507 (Endoglin/CD105 antigen)
37	sru-6	C33A12.8	n/a	chrIV 9,491,282	C. elegans SRU-6 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
38	K07E8.6	K07E8.6	n/a	chrII 638,824	contains similarity to Pfam domain PF08565 Cdc37 Hsp90 binding domain contains similarity to Interpro domains IPR004918 (Cdc37), IPR013874 (Cdc37, Hsp90 binding)
39	T28F3.5	T28F3.5	n/a	chrIV 17,297,711	contains similarity to Pfam domains PF01039 (Carboxyl transferase domain) , PF02786 (Carbamoyl-phosphate synthase L chain, ATP binding domain) , PF02785 (Biotin carboxylase C-terminal domain) , PF00364 (Biotin-requiring enzyme) , PF00289 (Carbamoyl-phosphate synthase L chain, N-terminal domain) contains similarity to Interpro domains IPR000022 (Carboxyl transferase), IPR005481 (Carbamoyl phosphate synthase, large subunit, N-terminal), IPR000089 (Biotin/lipoyl attachment), IPR016185 (PreATP-grasp-like fold), IPR011761 (ATP-grasp fold), IPR005482 (Biotin carboxylase, C-terminal), IPR011053 (Single hybrid motif), IPR005479 (Carbamoyl phosphate synthetase, large subunit, ATP-binding), IPR013815 (ATP-grasp fold, subdomain 1), IPR011764 (Biotin carboxylation region), IPR013816 (ATP-grasp fold, subdomain 2), IPR011763 (Acetyl-coenzyme A carboxyltransferase, C-terminal), IPR013817 (Pre-ATP-grasp fold), IPR011054 (Rudiment single hybrid motif)
40	fbxa-141	D1025.3	n/a	chrX 14,512,622	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
41	R02F2.8	R02F2.8	n/a	chrIII 5,494,067	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR002091 (Aromatic amino acid permease), IPR013057 (Amino acid transporter, transmembrane)
42	C24A11.2	C24A11.2	n/a	chrI 5,381,597
43	pat-10	F54C1.7	n/a	chrI 5,019,533	pat-10 encodes body wall muscle troponin C, the calcium-binding component of the troponin complex of actin thin filaments; PAT-10 is essential for muscle contraction and thus for completion of embryonic morphogenesis and elongation; by homology, PAT-10 likely functions to regulate body wall muscle contraction in response to changes in intracellular calcium; PAT-10 is expressed in body wall muscle but is also detected in vulval and anal muscles; expression in body wall muscle begins during early embryonic morphogenesis, concurrent with expression of other body wall muscle structural components.
44	Y37A1B.6	Y37A1B.6	n/a	chrIV 14,038,988	contains similarity to Bacillus amyloliquefaciens Beta-glucanase (BglA) (Fragment).; TR:Q44651
45	T06C12.9	T06C12.9	n/a	chrV 15,885,834	contains similarity to Pfam domain PF01679 Uncharacterized protein family UPF0057 contains similarity to Interpro domain IPR000612 (Protein of unknown function UPF0057)
46	str-3	M7.13	n/a	chrIV 11,099,437	str-3 encodes a seven transmembrane chemosensory receptor; STR-3 is expressed in the ASI chemosensory neurons; STR-3 expression in ASI is repressed in the presence of dauer pheromone at concentrations lower than that which induces dauer formation.
47	D1007.3	D1007.3	n/a	chrI 4,576,495
48	Y41C4A.8	Y41C4A.8	n/a	chrIII 11,707,793	contains similarity to Aedes aegypti Hypothetical conserved protein (Putative uncharacterized protein).; TR:Q1HQM0
49	F45E1.2	F45E1.2	n/a	chrX 8,003,850
50	T25G12.6	T25G12.6	n/a	chrX 17,227,557	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)