UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	btb-6	F45C12.7	0	chrII 1,715,821	C. elegans BTB-6 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
2	skr-15	F54D10.1	n/a	chrII 3,824,456	The skr-15 gene encodes a homolog of Skp1 in S. cerevisiae that has no known function in vivo, since skr-15(RNAi) animals are at least superficially normal.
3	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
4	F53F8.3	F53F8.3	n/a	chrV 20,684,555	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type)
5	nhr-263	F10G2.9	n/a	chrV 7,341,043	C. elegans NHR-263 protein; contains similarity to Pfam domain PF00104 Ligand-binding domain of nuclear hormone receptor contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
6	C35D10.13	C35D10.13	n/a	chrIII 4,877,976
7	F28D1.2	F28D1.2	n/a	chrIV 12,375,385	contains similarity to Homo sapiens Myelin transcription factor 1; ENSEMBL:ENSP00000327465
8	cdc-25.3	ZK637.11	n/a	chrIII 8,917,082	cdc-25.3 encodes a tyrosine phosphatase that is a member of the cell division cycle 25 (CDC25) family of cell cycle regulators that includes Schizosaccharomyces pombe CDC25 and Drosophila string; cdc-25.3 is one of four cdc-25 genes in C. elegans and while it is known to be expressed in hermaphrodites, the precise function of cdc-25.3 is not yet clear; cdc-25.3 may function redundantly with cdc-25.2 during embryonic development and redundantly with cdc-25.1, cdc-25.2, and emb-29 during meiosis.
9	meg-1	K02B9.1	n/a	chrX 13,928,257	meg-1 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-1 activity via mutation and RNAi indicates that MEG-1 is required for germline development and normal levels of fertility; specifically, MEG-1 is required maternally for normal germ cell proliferation and/or survival and for fully normal P granule segregation to the germ cell lineage; in regulating germline development, meg-1 likely functions redundantly with meg-2 and mes-1; meg-1 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; meg-1 mRNA is expressed in the proximal germline; MEG-1 localizes to P granules from the 4-to-8-cell through 100-cell stage of embryogenesis; MEG-1 localization to P granules partially requires MES-1 and, in turn, MES-1 localization to P granules is partly dependent on MEG-1.
10	kbp-1	R13F6.1	n/a	chrIII 6,869,906	C. elegans KBP-1 protein ;
11	F40F11.3	F40F11.3	n/a	chrIV 11,592,569	contains similarity to Saccharomyces cerevisiae involved intracellular protein transport, coiled-coil protein necessary for protein transport from ER to Golgi; SGD:YDL058W
12	F43G6.10	F43G6.10	n/a	chrII 11,809,738	contains similarity to Interpro domain IPR000694 (Proline-rich region)
13	T04D3.5	T04D3.5	n/a	chrI 13,330,023
14	C17E7.4	C17E7.4	n/a	chrV 3,893,699
15	flh-3	Y11D7A.13	n/a	chrIV 9,270,834	C. elegans FLH-3 protein; contains similarity to Pfam domain PF04500 FLYWCH zinc finger domain contains similarity to Interpro domains IPR007588 (Zinc finger, FLYWCH-type), IPR009057 (Homeodomain-like)
16	F41C6.3	F41C6.3	n/a	chrX 6,870,780
17	C13F10.2	C13F10.2	n/a	chrV 7,221,750	contains similarity to Drosophila melanogaster Flybase gene name is CG10681-PA;; FLYBASE:CG10681
18	R04D3.2	R04D3.2	n/a	chrX 13,285,808	contains similarity to Plasmodium falciparum Putative uncharacterized protein PFD0207c.; TR:Q8I1Y6
19	sdz-22	F56F4.1	n/a	chrI 6,148,622	C. elegans SDZ-22 protein; contains similarity to Pfam domain PF01060 Transthyretin-like family contains similarity to Interpro domain IPR001534 (Transthyretin-like)
20	F15A4.2	F15A4.2	n/a	chrII 12,463,181	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	C31G12.1	C31G12.1	n/a	chrV 18,180,590	contains similarity to Kaposi's sarcoma-associated herpesvirus K1 glycoprotein (Fragment).; TR:Q9WHA1
22	K04G2.10	K04G2.10	n/a	chrI 8,059,153	contains similarity to Homo sapiens Meiosis-specific nuclear structural protein 1; ENSEMBL:ENSP00000260453
23	fbxb-8	F49B2.1	n/a	chrI 14,302,931	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
24	C16A3.2	C16A3.2	n/a	chrIII 6,390,183	contains similarity to Pfam domain PF00782 Dual specificity phosphatase, catalytic domain contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000387 (Protein-tyrosine phosphatase), IPR000340 (Protein-tyrosine phosphatase, dual specificity)
25	fbxb-83	T17A3.6	n/a	chrIII 144,210	C. elegans FBXB-83 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
26	K03H1.7	K03H1.7	n/a	chrIII 9,947,654	contains similarity to Saccharomyces cerevisiae major low affinity 55 kDa Centromere/microtubule binding protein; SGD:YLR175W
27	dsl-6	H02I12.4	n/a	chrIV 11,397,523	dsl-6 encodes a putative transmembrane protein whose extracellular domain has a single DSL and EGF domains in series, somewhat like Delta/LAG-2; DSL-6 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-1, -2, -3, -5, -6, and -7.
28	B0393.3	B0393.3	n/a	chrIII 4,758,450	contains similarity to Pfam domains PF00560 (Leucine Rich Repeat) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR006553 (Leucine-rich repeat, cysteine-containing subtype)
29	Y43F11A.4	Y43F11A.4	n/a	chrII 12,120,633	contains similarity to Bos taurus Phosphatidylinositol 3-kinase regulatory gamma subunit (PI3-kinasesp85-gamma subunit) (PtdIns-3-kinase p85-gamma) (p55PIK).; SW:P55G_BOVIN
30	inx-3	F22F4.2	n/a	chrX 5,997,159	C. elegans INX-3 protein; contains similarity to Pfam domain PF00876 Innexin contains similarity to Interpro domain IPR000990 (Innexin)
31	C44B9.3	C44B9.3	n/a	chrIII 10,879,120	contains similarity to Trypanosoma cruzi Mucin-like protein.; TR:O61047
32	sra-25	T26E3.9	n/a	chrI 12,687,150	C. elegans SRA-25 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR003945 (NADH-plastoquinone oxidoreductase, chain 5), IPR000344 (Nematode chemoreceptor, Sra)
33	K02B12.2	K02B12.2	n/a	chrI 8,512,048	contains similarity to Interpro domain IPR008946 (Nuclear hormone receptor, ligand-binding)
34	Y106G6D.1	Y106G6D.1	n/a	chrI 10,108,184	contains similarity to Methanocaldococcus jannaschii DNA double-strand break repair rad50 ATPase.; SW:Q58718
35	F19B10.2	F19B10.2	n/a	chrII 3,676,170
36	ces-2	ZK909.4	n/a	chrI 14,963,425	ces-2 encodes a basic region leucine-zipper (bZIP) transcription factor, most similar in sequence and binding specificity to the PAR (proline- and acid-rich) subfamily of bZIP proteins; ces-2 is required to activate programmed cell death in the sister cells of the serotoninergic neurosecretory motor (NSM) neurons, and is transcriptionally inhibited by activated LET-60(G12V).
37	H04M03.3	H04M03.3	n/a	chrIV 5,892,434	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
38	meg-2	K02B9.2	n/a	chrX 13,924,518	meg-2 encodes a novel protein that localizes exclusively to P granules; originally identified by microarray analyses of germline-enriched transcripts, loss of meg-2 activity by itself results in no obvious abnormalities, but loss of meg-2 activity in meg-1 mutant animals indicates that meg-1 and meg-2 likely have redundant functions in germline development; meg-2 may also function redundantly with mes-1; meg-2 expression in the proximal germline is positively regulated by MPK-1, the C. elegans MAP kinase ortholog; a GFP::MEG-2 fusion protein localizes exclusively to P granules in the embryonic germ cell lineage.
39	msh-4	T02G5.6	n/a	chrII 7,078,297	C. elegans MSH-4 protein; contains similarity to Pfam domain PF00488 MutS domain V contains similarity to Interpro domain IPR000432 (DNA mismatch repair protein MutS, C-terminal)
40	F48C1.5	F48C1.5	n/a	chrI 5,317,876
41	sea-1	F19B10.9	n/a	chrII 3,672,747	sea-1 encodes a T-box transcription factor; during development, sea-1 functions, zygotically and in a dose-dependent manner, as an autosomal element of the X:A (X chromosome:autosome) ratio that determines C. elegans sex; in opposition to the X signal elements, SEA-1 positively regulates transcription of xol-1, the master sex-determination switch gene that is essential for male development and for setting the proper activity level of the dosage compensation complex; consistent with its role as a regulator of sex determination, SEA-1 is expressed in nuclei of early embryos from approximately the 20- to 100-cell stage of embryogenesis.
42	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
43	F10E9.5	F10E9.5	n/a	chrIII 8,307,934	contains similarity to Homo sapiens 29 kDa protein; ENSEMBL:ENSP00000381398
44	B0334.4	B0334.4	n/a	chrII 11,496,096	contains similarity to Pfam domain PF04707 PRELI-like family contains similarity to Interpro domain IPR006797 (MSF1)
45	cks-1	C09G4.3	n/a	chrIV 8,514,308	A homolog of Cks/Suc1, a highly conserved member of the eukaryotic cell cycle machinery that affects both meiosis and mitosis and has a role in the inactivation of the M-phase promoting factor (MPF) during early embryogenesis.
46	R53.6	R53.6	n/a	chrII 9,969,060	contains similarity to Pfam domain PF03651 Partner of SLD five, PSF1 contains similarity to Interpro domain IPR005339 (GINS complex, Psf1 component)
47	F15A4.10	F15A4.10	n/a	chrII 12,484,765	contains similarity to Saccharomyces cerevisiae Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate; SGD:YOR195W
48	Y6G8.3	Y6G8.3	n/a	chrV 17,602,355	contains similarity to Pfam domain PF00096 Zinc finger, C2H2 type contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR001781 (Zinc finger, LIM-type), IPR007087 (Zinc finger, C2H2-type)
49	btb-10	K02E7.9	2e-64	chrII 1,060,263	C. elegans BTB-10 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
50	T24C4.2	T24C4.2	n/a	chrIII 868,674