UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	ptr-8	F44F4.4	0	chrII 10,891,194	ptr-8 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-8 is weakly required for normal molting from L4 to adult stages; PTR-8 is also required for normal growth to full size and locomotion; PTR-8 is expressed in hypodermis.
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	glc-2	F25F8.2	n/a	chrI 4,886,565	glc-2 encodes the beta subunit of a glutamate-gated chloride channel; in vivo, GLC-2 is capable of forming homomeric glutamate-activated channels, as well as heteromeric channels with GLC-1 that can be activated by glutamate and avermectins, antihelmintics that inhibit pharyngeal pumping; as loss of glc-2 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GLC-2 in development and/or behavior is not yet known; however, GLC-2 expression is generally restricted to the pm4 pharyngeal muscles of larvae and adults, suggesting a role for GLC-2 in regulation of glutamatergic inhibition of pharyngeal pumping.
4	D2024.2	D2024.2	n/a	chrIV 7,244,813	contains similarity to Mus musculus Probable arylformamidase (EC 3.5.1.9) (Kynurenine formamidase) (KF).; SW:Q8K4H1
5	R53.4	R53.4	n/a	chrII 9,967,683	contains similarity to Homo sapiens 10 kDa protein; ENSEMBL:ENSP00000377740
6	W07G4.1	W07G4.1	n/a	chrV 13,033,814	contains similarity to Interpro domain IPR009050 ()
7	F08G12.3	F08G12.3	n/a	chrX 11,301,106	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I5Q0
8	F35E8.2	F35E8.2	n/a	chrV 15,906,320	contains similarity to Trichomonas vaginalis G3 Viral A-type inclusion protein, putative.; TR:A2DZ81
9	cyn-16	Y17G7B.9	n/a	chrII 12,032,664	cyn-16 encodes a highly diverged member of the cyclophilin family; CYN-16 exhibits low levels of peptidyl-prolyl cis/trans isomerase activity in vitro that is insensitive to the presence of cyclosporin A; a cyn-16::gfp fusion protein is expressed in the intestine during larval and adult stages of development, with particularly strong expression seen in the anterior and posterior ends; in dauer larvae, the cyn-16::gfp reporter is expressed in cell bodies and processes of ventral cord neurons and is no longer visible in the intestine.
10	T06E6.10	T06E6.10	n/a	chrV 15,418,719	contains similarity to Pfam domain PF01826 Trypsin Inhibitor like cysteine rich domain contains similarity to Interpro domains IPR002919 (Protease inhibitor I8, cysteine-rich trypsin inhibitor-like), IPR013032 (EGF-like region, conserved site)
11	K09F6.6	K09F6.6	n/a	chrII 2,277,012
12	F25F8.1	F25F8.1	n/a	chrI 4,890,200	contains similarity to Interpro domain IPR011042 (Six-bladed beta-propeller, TolB-like)
13	srw-31	K03D7.2	n/a	chrV 17,507,514	C. elegans SRW-31 protein; contains similarity to Pfam domain PF06976 Protein of unknown function (DUF1300) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR010726 (Protein of unknown function DUF1300), IPR000832 (GPCR, family 2, secretin-like), IPR000276 (GPCR, rhodopsin-like)
14	R03G8.1	R03G8.1	n/a	chrX 13,086,031	contains similarity to Pfam domain PF02995 Protein of unknown function (DUF229) contains similarity to Interpro domains IPR004245 (Protein of unknown function DUF229), IPR017850 (Alkaline-phosphatase-like, core domain)
15	ZK892.3	ZK892.3	n/a	chrII 10,002,830	contains similarity to Pfam domains PF07690 (Major Facilitator Superfamily) , PF00083 (Sugar (and other) transporter) contains similarity to Interpro domains IPR007114 (Major facilitator superfamily), IPR011701 (Major facilitator superfamily MFS-1), IPR005829 (Sugar transporter, conserved site), IPR005828 (General substrate transporter), IPR016196 (MFS general substrate transporter)
16	F58H1.4	F58H1.4	n/a	chrV 11,937,362	contains similarity to Interpro domain IPR006207 (Cystine knot, C-terminal)
17	C04E12.5	C04E12.5	n/a	chrV 3,359,866	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
18	srw-63	Y37A1B.10	n/a	chrIV 14,014,952	C. elegans SRW-63 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
19	srbc-52	F54B8.10	n/a	chrV 15,828,326	C. elegans SRBC-52 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
20	nas-1	F45G2.1	n/a	chrIII 13,407,525	nas-1 encodes an astacin-like metalloprotease.
21	srxa-16	F44G3.5	n/a	chrV 16,113,637	C. elegans SRXA-16 protein; contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR005047 (Protein of unknown function DUF286, G protein-coupled receptor-like putative Caenorhabditis species)
22	C14A6.3	C14A6.3	n/a	chrV 18,147,539	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
23	Y39F10A.1	Y39F10A.1	n/a	chrII 776,047
24	nas-18	K03B8.3	n/a	chrV 11,396,823	nas-18 encodes an astacin-like metalloprotease; loss of nas-18 activity via RNAi results in a reduction of fat content suggesting an abnormality in lipid metabolism.
25	F56F10.3	F56F10.3	n/a	chrX 863,092	F56F10.3 encodes the C. elegans cysteine dioxygenase ortholog; by homology to mammalian enzymes, the product of F56F10.3 is predicted to function in cysteine catabolism by catalyzing the oxidation of cysteine to cysteine sulfanate.
26	ZC116.1	ZC116.1	n/a	chrV 12,610,320	contains similarity to Interpro domain IPR001419 (HMW glutenin)
27	T26C12.2	T26C12.2	n/a	chrIV 3,264,607	contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
28	T25B2.1	T25B2.1	n/a	chrX 6,175,044	contains similarity to Pfam domains PF00620 (RhoGAP domain) , PF00130 (Phorbol esters/diacylglycerol binding domain (C1 domain)) contains similarity to Interpro domains IPR001060 (Cdc15/Fes/CIP4), IPR008936 (Rho GTPase activation protein), IPR000533 (Tropomyosin), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR000695 (H+ transporting ATPase, proton pump), IPR000198 (RhoGAP)
29	F42F12.3	F42F12.3	n/a	chrX 12,351,013	contains similarity to Pfam domain PF02544 3-oxo-5-alpha-steroid 4-dehydrogenase contains similarity to Interpro domains IPR001104 (3-oxo-5-alpha-steroid 4-dehydrogenase, C-terminal), IPR016636 (3-oxo-5-alpha-steroid 4-dehydrogenase)
30	C33C12.7	C33C12.7	n/a	chrII 2,174,952
31	math-2	C08F1.1	n/a	chrII 1,799,617	C. elegans MATH-2 protein; contains similarity to Pfam domain PF00917 MATH domain contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH)
32	K08D8.2	K08D8.2	n/a	chrIV 12,903,408	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q8GYZ7
33	cyp-33E1	C49C8.4	n/a	chrIV 8,646,858	C. elegans CYP-33E1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
34	F42A6.1	F42A6.1	n/a	chrIV 3,356,300
35	M02F4.1	M02F4.1	n/a	chrX 3,028,999	contains similarity to Homo sapiens Isoform 1 of Splicing factor, arginine/serine-rich 12; ENSEMBL:ENSP00000284041
36	C53A5.9	C53A5.9	n/a	chrV 14,557,956	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF07646 (Kelch motif) (3), PF02984 (Cyclin, C-terminal domain) contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR004367 (Cyclin, C-terminal), IPR006652 (Kelch repeat type 1), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
37	K08B4.5	K08B4.5	n/a	chrIV 6,087,860	contains similarity to Pfam domain PF00443 Ubiquitin carboxyl-terminal hydrolase contains similarity to Interpro domains IPR001394 (Peptidase C19, ubiquitin carboxyl-terminal hydrolase 2), IPR011009 (Protein kinase-like), IPR001019 (Guanine nucleotide binding protein (G-protein), alpha subunit)
38	srw-73	T03E6.6	n/a	chrV 16,587,756	C. elegans SRW-73 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
39	srw-8	F59D6.5	n/a	chrV 3,033,490	C. elegans SRW-8 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
40	D1053.3	D1053.3	n/a	chrX 11,731,700	contains similarity to Interpro domain IPR001208 (MCM)
41	T07D3.3	T07D3.3	n/a	chrII 895,627	contains similarity to Homo sapiens CGI16-iso; ENSEMBL:ENSP00000368599
42	F46B6.4	F46B6.4	n/a	chrV 9,778,673	contains similarity to Pfam domain PF01926 GTPase of unknown function contains similarity to Interpro domains IPR016496 (GTP-binding protein, HflX), IPR002917 (GTP-binding protein, HSR1-related), IPR003593 (AAA+ ATPase, core), IPR006073 (GTP1/OBG)
43	acy-2	C10F3.3	n/a	chrV 5,978,731	acy-2 encodes an adenylyl cyclase; an intragenic deletion of acy-2 is lethal at the first larval stage of development; the terminal phenotype resembles that seen in loss-of-function gsa-1 mutants.
44	R11D1.2	R11D1.2	n/a	chrV 12,709,668	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
45	grl-21	ZC168.5	n/a	chrIV 10,737,774	grl-21 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-21 is expressed in arcade cells and hypodermis; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
46	fip-4	F41E6.10	n/a	chrV 8,611,069	C. elegans FIP-4 protein
47	R07C12.2	R07C12.2	n/a	chrIV 4,149,092
48	Y47H9C.9	Y47H9C.9	n/a	chrI 11,900,113	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
49	str-46	C31B8.6	n/a	chrV 2,899,200	C. elegans STR-46 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
50	Y48A6C.1	Y48A6C.1	n/a	chrIII 11,104,510	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR007087 (Zinc finger, C2H2-type)