UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F44E5.3	F44E5.3	0	chrII 11,763,830	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000304160
2	rod-1	F55G1.4	n/a	chrIV 7,481,969	C. elegans ROD-1 protein ; contains similarity to Caenorhabditis remanei Putative RoughDeal (Fragment).; TR:Q4TTM7
3	K02E7.4	K02E7.4	n/a	chrII 1,073,572	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domain IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
4	T14G10.8	T14G10.8	n/a	chrIV 10,146,609	contains similarity to Homo sapiens Splice isoform 1 of P08235 Mineralocorticoid receptor; ENSEMBL:ENSP00000281330
5	sru-16	Y45F10B.4	n/a	chrIV 13,581,181	C. elegans SRU-16 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
6	lin-1	C37F5.1	n/a	chrIV 2,288,106	lin-1 encodes an Ets-domain-containing transcription factor that is a member of the ETS gene family that includes human ELK1, 3, and 4 (OMIM:600247); LIN-1 functions as a general effector of MAP kinase-mediated signaling; when MAP kinase is inactive, LIN-1 forms a complex with LIN-31/WH that inhibits vulval cell fate specification; upon MAP kinase activation (vulval induction), LIN-1 is phosphorylated, dissociates from LIN-31, and becomes inactive, thus allowing for vulval development.
7	E02H9.4	E02H9.4	n/a	chrIII 2,457,255	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
8	R148.2	R148.2	n/a	chrIII 3,184,321
9	taf-11.3	F43D9.5	n/a	chrIII 10,504,535	The taf-11.3 gene encodes an ortholog of human TATA-binding protein associated factor TAF11 (TAFII28, OMIM:600772) that is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-11.3 is required for proper post-embryonic development.
10	F48A11.4	F48A11.4	n/a	chrII 214,905
11	F38A1.13	F38A1.13	n/a	chrIV 1,265,538
12	F53H4.3	F53H4.3	n/a	chrX 15,886,572	contains similarity to Mus musculus Ataxin-1 (Spinocerebellar ataxia type 1 protein homolog).; SW:ATX1_MOUSE
13	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
14	K06A4.4	K06A4.4	n/a	chrV 9,502,894	contains similarity to Pfam domain PF03083 MtN3/saliva family contains similarity to Interpro domain IPR004316 (MtN3 and saliva related transmembrane protein)
15	T08G5.7	T08G5.7	n/a	chrV 14,044,675	contains similarity to Interpro domains IPR015880 (Zinc finger, C2H2-like), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
16	F53A2.9	F53A2.9	n/a	chrIII 13,357,930	contains similarity to Pfam domain PF00646 (F-box domain)
17	srbc-61	F08E10.2	n/a	chrV 17,477,416	C. elegans SRBC-61 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
18	srz-74	K03D3.1	n/a	chrIV 16,330,219	C. elegans SRZ-74 protein ;
19	K02D7.2	K02D7.2	n/a	chrIV 312,624	K02D7.2 encodes an ortholog of human SNAI2/SLUG (OMIM:602150, mutated in Waardenburg syndrome type IID) and Drosophila ESCARGOT; based on its orthology to SNAI2, K02D7.2 is predicted to be a transcriptional inhibitor.
20	srt-13	ZC142.1	n/a	chrV 4,249,044	C. elegans SRT-13 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR002651 (Protein of unknown function DUF32), IPR000539 (Frizzled protein)
21	K09A11.1	K09A11.1	n/a	chrX 13,263,425	contains similarity to Pfam domains PF05699 (hAT family dimerisation domain) , PF02892 (BED zinc finger) contains similarity to Interpro domains IPR008906 (HAT dimerisation), IPR003656 (Zinc finger, BED-type predicted), IPR007087 (Zinc finger, C2H2-type)
22	ncs-1	C44C1.3	n/a	chrX 961,929	The ncs-1 gene encodes a neuronal calcium sensor protein that, along with calcium, is essential for thermotaxis along isothermal paths in thermal gradients.
23	F08C6.5	F08C6.5	n/a	chrX 7,560,915	contains similarity to Interpro domain IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site)
24	sel-2	F10F2.1	n/a	chrIII 4,604,205	sel-2 encodes a PH, BEACH and WD40 domain-containing protein that is homologous to mammalian neurobeachin/BCL8B and LRBA (LPS-responsive, beige-like anchor protein); during development, SEL-2 functions to regulate endosomal traffic in polarized epithelial cells such as the vulval precursor cells (VPCs) and intestinal cells; specifically, in a subset of the VPCs, SEL-2 activity is required for proper levels and apical localization of LIN-12/Notch and for LET-23/EGFR downregulation; sel-2::yfp reporters are expressed in a number of cell types, including the VPCs and intestinal cells; a rescuing SEL-2::GFP reporter is expressed most strongly in the rectal epithelial cells and hypodermal seam cells where it localizes to the cytoplasm and the perinuclear region.
25	C29F9.8	C29F9.8	n/a	chrIII 96,559
26	T02G5.11	T02G5.11	n/a	chrII 7,080,284	contains similarity to Pfam domain PF05741 Nanos RNA binding domain contains similarity to Interpro domain IPR008705 (Zinc finger, Nanos)
27	Y116A8C.25	Y116A8C.25	n/a	chrIV 17,076,616	contains similarity to Pfam domain PF03881 Fructosamine kinase contains similarity to Interpro domains IPR011009 (Protein kinase-like), IPR005581 (Fructosamine kinase)
28	grl-18	T05C3.4	n/a	chrV 5,487,265	grl-18 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
29	nhr-179	F16B4.11	n/a	chrV 1,616,853	C. elegans NHR-179 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
30	W09C5.9	W09C5.9	n/a	chrI 13,661,170	contains similarity to Lactococcus lactis Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartatestranscarbamylase) (ATCase).; SW:PYRB_LACLA
31	pfd-5	R151.9	n/a	chrIII 7,198,447	pfd-5 encodes a putative prefoldin 5 subunit, orthologous to human PFDN5 (OMIM:604899), that is required for normal microtubule growth, embryonic and larval viability, fertility, vulval development, and locomotion; PFD-5 is expressed in most, if not all, tissues; pfd-5(RNAi) animals show sterile progeny, larval arrest or lethality, uncoordination, and abnormal body shapes, and pfd-5(RNAi) embryos show a reduced microtubule growth rate.
32	ces-1	F43G9.11	n/a	chrI 8,634,989	ces-1 encodes a C2H2-type zinc finger transcription factor that is a member of the Snail family of proteins that includes Drosophila Scratch, Snail, and Slug, and human SNAIL and SLUG; although the normal function of CES-1 is not fully understood, gain-of-function mutations indicate that CES-1 can function as a transcriptional repressor that blocks programmed cell death in specific neurons by inhibiting expression of the cell-death activator EGL-1; in regulating EGL-1 expression, CES-1 appears to antagonize the transcriptional activity of the bHLH proteins, HLH-2 and HLH-3; despite its cell-type specific role in apoptosis, CES-1 expression is reportedly detected in many embryonic nuclei from the 100-cell stage of embryogenesis through the beginning of morphogenesis, with some CES-1 expression remaining at later embryonic stages; genetic studies indicate that CES-1 is negatively regulated by the bZIP transcription factor CES-2, which can bind CES-1 upstream sequences in vitro and thus may directly regulate CES-1 transcription in vivo
33	F58F6.3	F58F6.3	n/a	chrIV 1,375,965
34	C41D11.6	C41D11.6	n/a	chrI 4,461,426
35	ZK1098.5	ZK1098.5	n/a	chrIII 9,526,211	ZK1098.5 encodes a unfamiliar protein that is individually dispensable for viability and gross morphology in RNAi assays, but is cotranscribed with ZK1098.1 and thus might act in concert with it.
36	F20H11.6	F20H11.6	n/a	chrIII 6,599,869
37	sprr-2	F42D1.3	n/a	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
38	srab-13	F59A7.3	n/a	chrV 2,026,295	C. elegans SRAB-13 protein ;
39	clec-165	F38A1.10	n/a	chrIV 1,246,135	C. elegans CLEC-165 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR001680 (WD40 repeat), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
40	F44E5.2	F44E5.2	1e-27	chrII 11,770,321	contains similarity to Pfam domain PF00560 Leucine Rich Repeat
41	fbxb-76	H02I12.2	n/a	chrIV 11,378,732	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
42	str-134	C05E4.6	n/a	chrV 744,563	C. elegans STR-134 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
43	Y63D3A.8	Y63D3A.8	n/a	chrI 14,116,402	contains similarity to Interpro domains IPR002114 (Phosphotransferase system, HPr serine phosphorylation site), IPR006634 (TRAM, LAG1 and CLN8 homology)
44	Y54G11A.11	Y54G11A.11	n/a	chrII 14,350,230	contains similarity to Pfam domain PF05129 Transcription elongation factor Elf1 like contains similarity to Interpro domain IPR007808 (Protein of unknown function DUF701, zinc-binding putative)
45	C41D11.4	C41D11.4	n/a	chrI 4,442,876
46	W08F4.10	W08F4.10	n/a	chrII 590,892	contains similarity to Interpro domain IPR000169 (Peptidase, cysteine peptidase active site)
47	Y52B11A.9	Y52B11A.9	n/a	chrI 11,036,452	contains similarity to Interpro domains IPR003604 (Zinc finger, U1-type), IPR005824 (KOW), IPR002358 (Ribosomal protein L6, conserved site-1), IPR007087 (Zinc finger, C2H2-type)
48	H42K12.2	H42K12.2	n/a	chrX 1,319,512
49	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
50	B0379.2	B0379.2	n/a	chrI 10,071,342	contains similarity to Saccharomyces cerevisiae Possible role for UBP3 in controlling the activity or assembly of the SIR protein complex.; SGD:YER151C