UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	sprr-2	F42D1.3	0	chrX 14,802,137	C. elegans SPRR-2 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
2	EEED8.4	EEED8.4	n/a	chrII 5,410,795	contains similarity to Pfam domain PF00076 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) contains similarity to Interpro domains IPR002952 (Eggshell protein), IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
3	Y57G11A.4	Y57G11A.4	n/a	chrIV 14,484,352	contains similarity to Interpro domain IPR005018 (DOMON related)
4	fbxb-76	H02I12.2	n/a	chrIV 11,378,732	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
5	Y43F4B.7	Y43F4B.7	n/a	chrIII 13,310,326	contains similarity to Pfam domain PF01490 Transmembrane amino acid transporter protein contains similarity to Interpro domains IPR013057 (Amino acid transporter, transmembrane), IPR003568 (Cytochrome c-type biogenesis protein CcmF)
6	C43H6.7	C43H6.7	n/a	chrX 2,400,426	contains similarity to Pfam domain PF01529 DHHC zinc finger domain contains similarity to Interpro domains IPR001594 (Zinc finger, DHHC-type), IPR016201 (Plexin-like fold)
7	srz-74	K03D3.1	n/a	chrIV 16,330,219	C. elegans SRZ-74 protein ;
8	frk-1	T04B2.2	n/a	chrIV 10,044,780	frk-1 encodes a non-receptor tyrosine kinase orthologous to the human proto-oncogene Fer; frk-1 is an essential gene required early for embryonic cell proliferation and later in embryonic epidermal cells for enclosure, morphogenesis and late stages of differentiation; FRK-1's role in embryonic development is independent of its kinase domain, and when expressed in cultured mammalian cells, FRK-1 disrupts cell adhesion; FRK-1 is initially expressed in all cells of the early embryo where it localizes to nuclei and points of cell-cell contact; later expression is seen in epithelial cells, body wall muscle, and the adult germline, including mature sperm; FRK-1 expression in epidermal cells requires activity of the ELT-1 GATA transcription factor, and FRK-1 localization to the plasma membrane requires PAT-3/Beta-integrin, JAC-1/p120 catenin, and HMP-2/Beta-catenin with which FRK-1 interacts in vitro.
9	T07F12.2	T07F12.2	n/a	chrX 4,891,246	contains similarity to Pfam domain PF02225 PA domain contains similarity to Interpro domain IPR003137 (Protease-associated PA)
10	srbc-17	C45H4.3	n/a	chrV 2,178,415	C. elegans SRBC-17 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
11	W09C5.9	W09C5.9	n/a	chrI 13,661,170	contains similarity to Lactococcus lactis Aspartate carbamoyltransferase (EC 2.1.3.2) (Aspartatestranscarbamylase) (ATCase).; SW:PYRB_LACLA
12	C41D11.6	C41D11.6	n/a	chrI 4,461,426
13	Y116A8C.22	Y116A8C.22	n/a	chrIV 17,047,371	contains similarity to Pfam domain PF02178 AT hook motif contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR000116 (High mobility group proteins HMG-I and HMG-Y), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011011 (Zinc finger, FYVE/PHD-type)
14	taf-11.3	F43D9.5	n/a	chrIII 10,504,535	The taf-11.3 gene encodes an ortholog of human TATA-binding protein associated factor TAF11 (TAFII28, OMIM:600772) that is a component of the TFIID general transcription factor that recognizes the transcription start site; TAF-11.3 is required for proper post-embryonic development.
15	E02H9.4	E02H9.4	n/a	chrIII 2,457,255	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
16	F08C6.5	F08C6.5	n/a	chrX 7,560,915	contains similarity to Interpro domain IPR003016 (2-oxo acid dehydrogenase, lipoyl-binding site)
17	F53H1.3	F53H1.3	n/a	chrIV 1,334,268	contains similarity to Pfam domain PF07792 Protein of unknown function (DUF1630) contains similarity to Interpro domain IPR012860 (Protein of unknown function DUF1630)
18	Y54E2A.6	Y54E2A.6	n/a	chrII 14,768,030	contains similarity to Pfam domains PF00270 (DEAD/DEAH box helicase) (2), PF00271 (Helicase conserved C-terminal domain) (2), PF02889 (Sec63 Brl domain) (2)contains similarity to Interpro domains IPR011545 (DNA/RNA helicase, DEAD/DEAH box type, N-terminal), IPR004179 (Sec63), IPR014021 (Helicase, superfamily 1 and 2, ATP-binding), IPR003593 (AAA+ ATPase, core), IPR014001 (DEAD-like helicase, N-terminal), IPR001650 (DNA/RNA helicase, C-terminal)
19	C43H6.4	C43H6.4	n/a	chrX 2,405,689
20	K09B11.3	K09B11.3	n/a	chrIV 13,430,380	contains similarity to Homo sapiens DJ614O4.3; ENSEMBL:ENSP00000305301
21	clec-93	ZK39.4	n/a	chrI 11,143,094	C. elegans CLEC-93 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
22	K10H10.6	K10H10.6	n/a	chrII 14,504,011	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
23	T24H10.1	T24H10.1	n/a	chrII 9,099,835	contains similarity to Pfam domains PF07500 (Transcription factor S-II (TFIIS), central domain) , PF08711 (Transcription elongation factor S-II protein N terminal) , PF01096 (Transcription factor S-II (TFIIS)) contains similarity to Interpro domains IPR001222 (Zinc finger, TFIIS-type), IPR003618 (Transcription elongation factor S-II, central region), IPR014754 (Transcription elongation factor, TFIIS, N-terminal, fungal-type), IPR003617 (Transcription elongation factor, TFIIS/CRSP70, N-terminal, sub-type), IPR014765 (Transcription elongation factor, TFIIS/CRSP70, N-terminal), IPR016492 (Transcription elongation factor, IIS), IPR006289 (Transcription elongation factor, TFIIS), IPR010990 (Transcription elongation factor, TFIIS/elongin A/CRSP70, N-terminal)
24	EEED8.6	EEED8.6	n/a	chrII 5,385,733	EEED8.6 encodes an ATP/ADP-activated metallocarboxypeptidase, orthologous to mammalian AGBL4 proteins, that may function in vivo as an alpha-tubulin C-terminal tyrosine carboxypeptidase; recombinant EEED8.6 is active in vitro on several different C-terminal amino acids of synthetic peptide substrates (with carboxypeptidase A- and B-like, but not O-like specificity); unlike most carboxypeptidases, but like tubulin carboxypeptidase, EEED8.6 is inhibited by high salt or by Z-Glu-Tyr dipeptide; EEED8.6 and its mammalian AGBL4 orthologs, along with other proteins such as mammalian AGBL5, comprise a M14D2 peptidase subfamily; by homolog-based structural modelling, EEED8.6 is predicted to have an unusually open active site.
25	thoc-1	T02H6.2	n/a	chrII 705,367	C. elegans THOC-1 protein ; contains similarity to Danio rerio THO complex 1.; TR:Q7SYB2
26	C50E3.2	C50E3.2	n/a	chrV 7,610,647	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
27	B0432.9	B0432.9	n/a	chrII 283,160	contains similarity to Pfam domain PF00753 Metallo-beta-lactamase superfamily contains similarity to Interpro domain IPR001279 (Beta-lactamase-like)
28	Y40B10B.1	Y40B10B.1	n/a	chrV 1,960,770	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))
29	Y43F8B.11	Y43F8B.11	n/a	chrV 19,471,547	contains similarity to Campylobacter coli CadF precursor (Outer membrane protein).; TR:O06895
30	C26E1.1	C26E1.1	n/a	chrV 13,297,767	contains similarity to Rattus norvegicus GLUT4 vesicle protein.; TR:Q9Z1X1
31	ing-3	Y51H1A.4	n/a	chrII 13,879,211	Y51H1A.4 is orthologous to the human gene P33ING1B (ING1; OMIM:601566), which when mutated leads to disease.
32	dat-1	T23G5.5	n/a	chrIII 9,244,759	dat-1 encodes a plasma membrane dopamine transporter; DAT-1 is predicted to regulate dopaminergic neurotransmission via reuptake of dopamine into presynaptic neurons; when expressed in HeLa cells, DAT-1 exhibits high affinity, saturable dopamine transport; further, in primary cultures of C. elegans dopaminergic neurons, DAT-1 also exhibits a channel mode of conduction that leads to membrane depolarization; in hermaphrodites, dat-1 is expressed in the eight dopaminergic neurons (4 CEPs, 2 ADEs, and 2 PDEs), while in males dat-1 is additionally expressed in the three pairs of tail dopaminergic neurons; dat-1 expression begins during embryogenesis with the exception of expression in the PDE neurons which are born postembryonically.
33	K02E7.4	K02E7.4	n/a	chrII 1,073,572	contains similarity to Pfam domain PF02214 K+ channel tetramerisation domain contains similarity to Interpro domain IPR003131 (Potassium channel, voltage dependent, Kv, tetramerisation)
34	btb-12	ZC204.3	n/a	chrII 1,655,685	C. elegans BTB-12 protein; contains similarity to Pfam domain PF00651 BTB/POZ domain contains similarity to Interpro domains IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
35	F33D11.5	F33D11.5	n/a	chrI 5,836,021	contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
36	Y63D3A.8	Y63D3A.8	n/a	chrI 14,116,402	contains similarity to Interpro domains IPR002114 (Phosphotransferase system, HPr serine phosphorylation site), IPR006634 (TRAM, LAG1 and CLN8 homology)
37	T14G12.6	T14G12.6	n/a	chrX 3,758,129	contains similarity to Pfam domain PF02343 Domain of unknown function DUF130 contains similarity to Interpro domain IPR003326 (Protein of unknown function DUF130)
38	nhr-78	F36A4.14	n/a	chrIV 4,276,441	C. elegans NHR-78 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
39	srh-131	Y102A5C.31	n/a	chrV 17,006,090	C. elegans SRH-131 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
40	F44E5.3	F44E5.3	n/a	chrII 11,763,830	contains similarity to Homo sapiens Hypothetical protein; ENSEMBL:ENSP00000304160
41	T21B4.3	T21B4.3	n/a	chrII 12,495,897	contains similarity to Pfam domain PF01681 C6 domain contains similarity to Interpro domain IPR002601 (Protein of unknown function C6)
42	chw-1	F22E12.2	n/a	chrV 10,463,355	C. elegans CHW-1 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013753 (Ras)
43	C30E1.4	C30E1.4	n/a	chrX 16,924,785	contains similarity to Homo sapiens SID1 transmembrane family member 1 precursor; ENSEMBL:ENSP00000264852
44	str-20	C05E4.2	n/a	chrV 757,182	C. elegans STR-20 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	R148.2	R148.2	n/a	chrIII 3,184,321
46	F36D1.1	F36D1.1	n/a	chrI 11,278,248	contains similarity to Interpro domain IPR006578 (MADF)
47	srw-117	C44C3.6	n/a	chrV 2,982,800	C. elegans SRW-117 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
48	F28C10.3	F28C10.3	n/a	chrX 533,819	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
49	ncs-1	C44C1.3	n/a	chrX 961,929	The ncs-1 gene encodes a neuronal calcium sensor protein that, along with calcium, is essential for thermotaxis along isothermal paths in thermal gradients.
50	coq-6	K07B1.2	n/a	chrV 9,337,783	coq-6 encodes a putative flavin-dependent aromatic-ring monooxygenase, homologous to yeast COQ6; COQ-6 is required for ubiquinone (coenzyme Q9) biosynthesis and for normally short lifespan; coq-6(RNAi) animals have reduced levels of coenzyme Q9 and superoxide, and have abnormally long lifespans.