UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	lin-49	F42A9.2	0	chrIV 8,623,398	C. elegans LIN-49 protein; contains similarity to Pfam domains PF00628 (PHD-finger) , PF00439 (Bromodomain) contains similarity to Interpro domains IPR001965 (Zinc finger, PHD-type), IPR001487 (Bromodomain), IPR002219 (Protein kinase C, phorbol ester/diacylglycerol binding), IPR011011 (Zinc finger, FYVE/PHD-type)
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	C35C5.6	C35C5.6	n/a	chrX 11,566,764	contains similarity to Drosophila melanogaster Flybase gene name is CG2478-PA;; FLYBASE:CG2478
4	ZK863.1	ZK863.1	n/a	chrV 12,169,192	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
5	srw-119	K12D9.7	n/a	chrV 2,999,188	C. elegans SRW-119 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
6	ZK524.4	ZK524.4	n/a	chrI 7,463,889	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
7	K03E5.1	K03E5.1	n/a	chrI 3,431,349	contains similarity to Pfam domain PF00431 CUB domain contains similarity to Interpro domains IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR000859 (CUB)
8	K10C9.4	K10C9.4	n/a	chrV 1,051,572	contains similarity to Interpro domain IPR003945 (NADH-plastoquinone oxidoreductase, chain 5)
9	C05C10.1	C05C10.1	n/a	chrII 9,918,735	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
10	F28G4.5	F28G4.5	n/a	chrV 16,290,444	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domains IPR002656 (Acyltransferase 3), IPR006621 (Nose resistant to fluoxetine-4, N-terminal)
11	C02B10.6	C02B10.6	n/a	chrIV 5,071,570	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR016130 (Protein-tyrosine phosphatase, active site), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
12	F09G2.2	F09G2.2	n/a	chrV 7,197,657	contains similarity to Interpro domain IPR011028 (Cyclin-like)
13	ZK643.1	ZK643.1	n/a	chrIII 8,934,736	contains similarity to Pfam domain PF00339 Arrestin (or S-antigen), N-terminal domain contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011021 (Arrestin-like, N-terminal)
14	srh-257	T06E6.6	n/a	chrV 15,409,280	C. elegans SRH-257 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR000175 (Sodium:neurotransmitter symporter), IPR003002 (7TM chemoreceptor, subfamily 1), IPR013333 (Ryanodine receptor, N-terminal)
15	C35C5.2	C35C5.2	n/a	chrX 11,539,654	contains similarity to Pfam domains PF04389 (Peptidase family M28) , PF02225 (PA domain) , PF04253 (Transferrin receptor-like dimerisation domain) contains similarity to Interpro domains IPR007365 (Transferrin receptor-like, dimerisation), IPR007484 (Peptidase M28), IPR003137 (Protease-associated PA)
16	wah-1	Y56A3A.32	n/a	chrIII 11,994,707	wah-1 encodes a putative flavin-adenine dinucleotide (FAD)-binding oxidoreductase orthologous to mammalian PDCD8 (AIF; OMIM:300169, mutated in Harlequin mice); WAH-1 is required for apoptotic DNA degratation, SCRM-1 phospholipid scramblase activity, phosphatidylserine exposure, rapid apoptosis during embryonic development, and rapid engulfment of apoptotic cells in the germline; WAH-1 is also required for normally rapid growth and large brood sizes, and has a subtle proapoptotic function revealed in ced-3 or ced-4 mutant backgrounds; WAH-1 is expressed in most, if not all, cells of embryos and larvae; WAH-1 is normally mitochondrial, but can be released into the cytosol and nucleus by EGL-1 and CED-3; residues 380-550 of WAH-1 specifically bind SCRM-1 in vitro, but not SCRM-2 through SCRM-4, and WAH-1 binding is required in liposomes for more than residual SCRM-1 activity; WAH-1 also binds and activates CPS-6, promoting apoptotic DNA degradation, and transgenic coexpression of WAH-1 with CPS-6 specifically induces ectopic CED-3-dependent apoptosis in touch receptor neurons; CPS-6 shares a genetic pathway with WAH-1, whereas CED-3, CED-4, CED-8, and NUC-1 act independently of it; WAH-1 is paralogous to C. elegans F20D6.11 and human AIFM3 (AIFL).
17	F42G2.6	F42G2.6	n/a	chrII 2,428,176	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR000533 (Tropomyosin), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
18	E03H4.4	E03H4.4	n/a	chrI 12,409,488	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
19	K03H6.4	K03H6.4	n/a	chrIV 1,519,644
20	sra-27	F18C5.1	n/a	chrII 6,569,673	C. elegans SRA-27 protein; contains similarity to Pfam domain PF02117 C.elegans Sra family integral membrane protein contains similarity to Interpro domains IPR000344 (Nematode chemoreceptor, Sra), IPR000276 (GPCR, rhodopsin-like)
21	C32B5.4	C32B5.4	n/a	chrII 980,130	contains similarity to Interpro domains IPR000931 (Adenovirus fibre protein), IPR008893 (WGR)
22	M01G5.3	M01G5.3	n/a	chrIII 1,513,690	contains similarity to Pfam domain PF07851 TMPIT-like protein contains similarity to Interpro domain IPR012926 (TMPIT-like)
23	clec-131	W10G11.7	n/a	chrII 3,575,385	C. elegans CLEC-131 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
24	C01G10.9	C01G10.9	n/a	chrV 15,083,391	contains similarity to Pfam domain PF01008 Initiation factor 2 subunit family contains similarity to Interpro domains IPR000649 (Initiation factor 2B related), IPR011559 (Initiation factor 2B alpha/beta/delta)
25	cyp-33C1	C45H4.2	n/a	chrV 2,180,672	C. elegans CYP-33C1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV), IPR002397 (Cytochrome P450, B-class)
26	cyp-34A1	T10H4.10	n/a	chrV 15,286,741	C. elegans CYP-34A1 protein; contains similarity to Pfam domain PF00067 Cytochrome P450 contains similarity to Interpro domains IPR001128 (Cytochrome P450), IPR002401 (Cytochrome P450, E-class, group I), IPR002403 (Cytochrome P450, E-class, group IV)
27	ceeh-1	K02F3.6	n/a	chrIII 830,425	ceeh-1 encodes a soluble epoxide hydrolase (sEH) orthologous to human ABHD7 and ABHD9; recombinant CEEH-1 is biochemically active in vitro on epoxyeicosatrienoic acids and leukotoxins (EpOMEs); conversely, CEEH-1 is inhibited by urea-based antagonists of mammalian sEH that elevate EpOME levels when fed to C. elegans; perhaps because of genetic redundancy with its paralog CEEH-2, CEEH-1 has no obvious function in mass RNAi assays.
28	str-112	F10D2.4	n/a	chrV 7,137,353	C. elegans STR-112 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	F13G3.10	F13G3.10	n/a	chrI 7,313,972	contains similarity to Interpro domain IPR010989 (t-SNARE)
30	C01B10.9	C01B10.9	n/a	chrIV 6,633,581	contains similarity to Pfam domain PF01663 Type I phosphodiesterase / nucleotide pyrophosphatase contains similarity to Interpro domains IPR002591 (Type I phosphodiesterase/nucleotide pyrophosphatase/phosphate transferase), IPR017849 (Alkaline phosphatase-like, alpha/beta/alpha), IPR017850 (Alkaline-phosphatase-like, core domain)
31	F09E5.10	F09E5.10	n/a	chrII 5,349,294	contains similarity to Interpro domain IPR009079 (Four-helical cytokine-like, core)
32	hyl-2	K02G10.6	n/a	chrX 4,698,095	hyl-2 encodes a predicted transmembrane protein that is related to Saccharomyces cerevisiae LAG1 (longevity assurance gene), a protein preferentially expressed in young yeasts; by homology, HYL-2 is predicted to have several possible functions, including regulation of lipid, particularly ceramide, biosynthesis, regulation of lipid transport, and regulation of protein translocation in the endoplasmic reticulum ; however, as loss of hyl-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, the precise role of hyl-2 in C. elegans development and/or behavior is not yet known.
33	tsp-8	F33C8.3	n/a	chrX 14,727,975	tsp-8 is orthologous to the human gene KANGAI 1 (SUPPRESSION OF TUMORIGENICITY 6, PROSTATE; CD82 ANTIGEN (R2 LEUKOCYTE ANTIGEN, ANTIGEN DETECTED BY MONOCLONAL AND ANTIBODY IA4)) (KAI1; OMIM:600623), which when mutated leads to disease.
34	acy-1	F17C8.1	n/a	chrIII 4,726,505	The acy-1 gene encodes a protein with 40% identity to mammalian adenylyl cyclases, most closely related to the divergent mouse isoform type IX, that affects viability, muscle contraction, locomotion, and molting; it acts genetically downstream of gsa-1 and is expressed in excitable cells.
35	prg-2	C01G5.2	n/a	chrIV 6,528,248	C. elegans PRG-2 protein; contains similarity to Pfam domains PF02171 (Piwi domain) , PF02170 (PAZ domain) contains similarity to Interpro domains IPR003165 (Stem cell self-renewal protein Piwi), IPR003100 (Argonaute and Dicer protein, PAZ), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
36	F26C11.3	F26C11.3	n/a	chrII 9,906,024	contains similarity to Interpro domains IPR000436 (Sushi/SCR/CCP), IPR016060 (Complement control module)
37	F52C6.14	F52C6.14	n/a	chrII 1,932,827	contains similarity to Interpro domain IPR013032 (EGF-like region, conserved site)
38	Y75B8A.7	Y75B8A.7	n/a	chrIII 12,156,145	contains similarity to Pfam domain PF04006 Mpp10 protein contains similarity to Interpro domains IPR012173 (U3 small nucleolar ribonucleoprotein complex, subunit Mpp10p), IPR007151 (Mpp10 protein)
39	srg-8	T12A2.9	n/a	chrIII 6,254,139	C. elegans SRG-8 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
40	C01G5.8	C01G5.8	n/a	chrIV 6,550,691	contains similarity to Pfam domain PF08774 VRR-NUC domain contains similarity to Interpro domain IPR014883 (VRR-NUC)
41	grl-13	F32D1.4	n/a	chrV 4,363,652	grl-13 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central low-complexity region, and a C-terminal Ground-like (Grl) domain; GRL-13 is expressed in larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
42	C04G6.4	C04G6.4	n/a	chrII 5,082,452	contains similarity to Interpro domain IPR000694 (Proline-rich region)
43	Y75B8A.31	Y75B8A.31	n/a	chrIII 12,353,159	contains similarity to Homo sapiens Isoform 1 of UPF0528 protein C5orf21 precursor; ENSEMBL:ENSP00000265139
44	srh-184	D1054.12	n/a	chrV 10,797,485	C. elegans SRH-184 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
45	T26A5.8	T26A5.8	n/a	chrIII 6,462,478	contains similarity to Pfam domain PF00808 Histone-like transcription factor (CBF/NF-Y) and archaeal histone contains similarity to Interpro domains IPR009072 (Histone-fold), IPR003958 (Transcription factor CBF/NF-Y/archaeal histone)
46	C37A2.6	C37A2.6	n/a	chrI 6,788,535	contains similarity to Pfam domain PF06325 Ribosomal protein L11 methyltransferase (PrmA) contains similarity to Interpro domain IPR010456 (Ribosomal L11 methyltransferase)
47	srb-9	F37C12.16	n/a	chrIII 7,174,868	C. elegans SRB-9 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
48	nhr-38	K01H12.3	n/a	chrIV 9,711,556	C. elegans NHR-38 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type)
49	C18H7.1	C18H7.1	n/a	chrIV 618,237	contains similarity to Pfam domain PF00092 von Willebrand factor type A domain contains similarity to Interpro domain IPR002035 (von Willebrand factor, type A)
50	C01B12.5	C01B12.5	n/a	chrII 10,817	contains similarity to Pfam domain PF01062 Bestrophin contains similarity to Interpro domains IPR000615 (Bestrophin), IPR000802 (Arsenical pump membrane protein)