UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F40G9.6	F40G9.6	6e-74	chrIII 179,840
2	W05B10.4	W05B10.4	n/a	chrV 12,668,893	contains similarity to Pfam domain PF00788 Ras association (RalGDS/AF-6) domain contains similarity to Interpro domain IPR000159 (Ras-association)
3	gst-2	K08F4.6	n/a	chrIV 10,140,892	C. elegans GST-2 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
4	srh-39	C06A8.7	n/a	chrII 7,764,656	C. elegans SRH-39 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
5	K10G6.4	K10G6.4	n/a	chrII 3,973,888	contains similarity to Interpro domain IPR000533 (Tropomyosin)
6	C55A1.4	C55A1.4	n/a	chrV 15,642,939	contains similarity to Escherichia coli TolA protein.; SW:TOLA_ECOLI
7	ZK816.1	ZK816.1	n/a	chrX 3,359,733
8	srh-251	R08H2.4	n/a	chrV 15,379,118	C. elegans SRH-251 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
9	srbc-9	C18B10.3	n/a	chrV 7,489,768	C. elegans SRBC-9 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
10	cfi-1	T23D8.8	n/a	chrI 9,997,318	cfi-1 encodes a DNA-binding protein containing an AT-rich interaction domain (ARID) that affects differentiation of the URA sensory neurons, AVD, and PVC interneurons; acts downstream of UNC-86 and LIN-32 in controlling URA and IL2 cell fate, and is expressed in some neurons and muscle cells.
11	fmo-2	K08C7.5	n/a	chrIV 10,683,426	fmo-2 encodes a flavin-containing monoxygenase homologous to human FMO1, FMO2, and FMO3 (OMIM:602079, mutated in trimethylaminuria).
12	sri-13	M01G12.13	n/a	chrI 12,141,648	C. elegans SRI-13 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
13	F23C8.12	F23C8.12	n/a	chrI 2,451,478
14	C37C3.10	C37C3.10	n/a	chrV 7,862,685
15	T10C6.2	T10C6.2	n/a	chrV 16,013,354	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	F10E9.1	F10E9.1	n/a	chrIII 8,323,702
17	C06B3.1	C06B3.1	n/a	chrV 13,903,319	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR008365 (Prostanoid receptor), IPR003002 (7TM chemoreceptor, subfamily 1)
18	nhr-148	C03G6.10	n/a	chrV 7,342,974	C. elegans NHR-148 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
19	srx-85	F38B7.4	n/a	chrV 11,553,428	C. elegans SRX-85 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
20	R10H10.4	R10H10.4	n/a	chrIV 10,394,780	contains similarity to Arabidopsis thaliana T15B16.1 protein.; TR:Q9ZSH8
21	W04G5.7	W04G5.7	n/a	chrI 11,653,511	contains similarity to Pfam domain PF05075 Protein of unknown function (DUF684) contains similarity to Interpro domain IPR007767 (Protein of unknown function DUF684)
22	srd-33	T19H12.4	n/a	chrV 4,873,237	C. elegans SRD-33 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR003002 (7TM chemoreceptor, subfamily 1), IPR000276 (GPCR, rhodopsin-like)
23	cpx-2	K03A11.2	n/a	chrX 13,067,761	C. elegans CPX-2 protein; contains similarity to Pfam domain PF05835 Synaphin protein contains similarity to Interpro domain IPR008849 (Synaphin)
24	F55A4.3	F55A4.3	n/a	chrX 1,023,626
25	ceh-16	C13G5.1	n/a	chrIII 8,624,237	ceh-16 encodes a homeodomain protein orthologous to Drosophila and vertebrate Engrailed proteins involved in segment and appendage development; ceh-16 is an essential gene required for proper specification and differentiation of the lateral seam cells during embryonic development; in specifying seam cell fates, CEH-16 appears to act as a transcriptional regulator, repressing expression of the eff-1 gene required for cell fusion and inducing expression of seam cell-specific genes such as elt-5/GATA, nhr-73, and nhr-74; a rescuing CEH-16::GFP fusion protein is first expressed in the early embryo in cells of the AB lineage; in later embryonic stages CEH-16::GFP is seen in all lateral seam cell nuclei as well as in some anterior neurons; during postembryonic development, CEH-16::GFP is expressed in the DA1 and DD1 motorneurons.
26	C18A11.2	C18A11.2	n/a	chrX 8,067,797
27	aqp-5	C35A5.1	n/a	chrV 10,492,631	aqp-5 encodes a putative aquaporin with no known substrate, since AQP-5 expressed in Xenopus oocytes has no effect on water, glycerol, or urea permeability; AQP-5 also has no function in mass RNAi assays, perhaps reflecting genetic redundancy with its paralogs AQP-4 and AQP-6; AQP-5 is expressed in I1 and I2 pharyngeal interneurons, and is orthologous to human AQP8 (OMIM:603750).
28	C55A1.6	C55A1.6	n/a	chrV 15,648,434	contains similarity to Lactococcus lactis Protein maturation protein.; TR:Q9CEV9
29	srj-54	F37B4.11	n/a	chrV 2,859,248	C. elegans SRJ-54 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR006069 (ATPase, P-type cation exchange, alpha subunit)
30	F41H8.2	F41H8.2	n/a	chrV 827,588	contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
31	gpa-10	C55H1.2	n/a	chrV 6,853,746	gpa-10 encodes a member of the G protein alpha subunit family of heterotrimeric GTPases; it is expressed in ADF, ASI, ASJ, ALN, CAN, LUA, and the spermatheca.
32	C31H5.5	C31H5.5	n/a	chrI 9,048,863	contains similarity to Mus musculus Eukaryotic translation initiation factor 2 subunit 2 (Eukaryoticstranslation initiation factor 2 beta subunit) (eIF-2-beta).; SW:IF2B_MOUSE
33	F08D12.13	F08D12.13	n/a	chrII 2,795,880
34	F58G1.7	F58G1.7	n/a	chrII 12,945,904	contains similarity to Interpro domain IPR008075 (Lipocalin-1 receptor)
35	F35C5.11	F35C5.11	n/a	chrII 12,909,598	contains similarity to Mus musculus Lymphocyte antigen Ly-6D precursor (Thymocyte B cell antigen) (ThB).; SW:LY6D_MOUSE
36	F08H9.4	F08H9.4	n/a	chrV 14,463,959	F08H9.4 encodes a heat shock protein (HSP) of the HSP16 class; unlike most HSP16s in C. elegans, it is specifically expressed in a particular tissue (the excretory canal and ventral nerve-cord neurons), and its expression is only mildly induced by heat shock; however, F08H9.4 expression is increased by heat shock, is induced in a new tissue type (intestine) by heat shock, and probably aids heat shock resistance, since F08H9.4(RNAi) animals die as embryos in heat shock at a higher rate than normal; in general, HSP16 proteins are thought to act as passive ligands for unfolded proteins that keep them safe from aggregation until the proteins can be refolded by a large (ATP-consuming) HSP.
37	pin-2	F07C6.1	n/a	chrIV 12,794,963	pin-2 encodes a LIM domain-containing protein that, along with UNC-97, comprises the two C. elegans members of the PINCH family of predicted adapter proteins; based upon its similarity to Drosophila and vertebrate members of the PINCH family, PIN-2 is predicted to play a role in regulation of cell morphology, motility, and survival, but as loss of pin-2 via large-scale RNAi results in no obvious defects, the precise role of PIN-2 in C. elegans development and/or behavior is not yet known; a PIN-2::GFP fusion protein is first expressed in embryos just prior to hatching and in early larvae is seen in several neurons, including the PVT neuron, and in intestinal cells; during postembryonic development, neuronal expression continues, whereas intestinal expression gradually declines; PIN-2 localizes to the cytoplasm and to the nucleus, and in neurons, is seen in axonal processes and varicosities.
38	clec-198	C49C3.13	n/a	chrIV 17,349,079	C. elegans CLEC-198 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
39	sra-39	T21H8.4	n/a	chrX 13,902,169	C. elegans SRA-39 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF03125 (C. elegans Sre G protein-coupled chemoreceptor) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR002184 (Serpentine beta receptor), IPR004151 (C. elegans Sre G protein-coupled chemoreceptor), IPR000344 (Nematode chemoreceptor, Sra)
40	C24A11.5	C24A11.5	n/a	chrI 5,385,191
41	ubc-1	C35B1.1	n/a	chrIV 4,104,634	ubc-1 encodes an E2 ubiquitin-conjugating enzyme that contains a novel 40 amino acid C-terminal tail, and is homologous to Saccharomyces cerevisiae RAD6/UBC2 which is involved in DNA repair; although loss of UBC-1 activity via RNA-mediated interference (RNAi) does not result in any abnormalities, UBC-1 is able to complement the DNA repair defects of a Saccharomyces cerevisiae rad6 null mutant, suggesting that UBC-1 can function in the DNA repair pathway; ubc-1 mRNA is detectable in embryos.
42	F01E11.3	F01E11.3	n/a	chrX 6,975,202
43	F45E6.3	F45E6.3	n/a	chrX 12,488,021	contains similarity to Pfam domain PF00566 TBC domain contains similarity to Interpro domain IPR000195 (RabGAP/TBC)
44	eak-4	F53B2.3	n/a	chrIV 12,524,964	eak-4 encodes a novel protein that contains an N-myristoylation signal; eak-4 acts in parallel to akt-1 to regulate insulin-like signaling and dauer formation; EAK-4 is expressed primarily in the neuroendocrine XXXL/R cells, where it associates with the plasma membrane.
45	C44H9.8	C44H9.8	n/a	chrV 12,847,707	contains similarity to Bacillus anthracis Sensory box histidine kinase PhoR.; TR:Q81L02
46	F38E9.4	F38E9.4	n/a	chrX 16,452,168
47	nlp-10	F37A8.4	n/a	chrIII 3,934,743	nlp-10 encodes four predicted neuropeptide-like proteins; nlp-10 is part of a GGxY neuropeptide family that has members in several other nematode species; nlp-10 is expressed in a variety of neurons, including ASK, ADL, CAN, two lateral neurons, two anterior pharyngeal neurons, one tail neuron, and one male tail neuron; as loss of nlp-10 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of nlp-10-encoded peptides in development and/or behavior is not yet known.
48	C08F11.2	C08F11.2	n/a	chrIV 13,622,516	contains similarity to Methanobacterium thermoautotrophicum Hypothetical protein MTH421.; SW:Y421_METTH
49	F10A3.11	F10A3.11	n/a	chrV 16,163,213	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
50	C13A2.7	C13A2.7	n/a	chrV 7,266,655