UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	hch-1	F40E10.1	0	chrX 14,698,114	hch-1 encodes a member of the zinc-dependent metalloprotease family that contains an epidermal growth factor-like domain, a CUB domain, and a TSP1 domain and affects hatching and QL neuroblast migration.
2	C08F1.6	C08F1.6	n/a	chrII 1,787,707
3	sdz-14	F14B6.1	n/a	chrI 12,216,990	C. elegans SDZ-14 protein ;
4	F23D12.5	F23D12.5	n/a	chrX 14,450,814	F23D12.5 encodes a putative histone H3 di/trimethyllysine-27 (H3K27me2/me3) demethylase; F23D12.5 contains a C-terminal JmjC domain, and is homologous to human JMJD3, UTX (OMIM:300128), and UTY (OMIM:400009); F23D12.5 is expected to antagonize transcriptional repression by polycomb repressor complexes, which mark stem cells (and presumably germline) by H3K27me3-mediated repression of somatic genes; however, F23D12.5 has no obvious function in mass RNAi assays.
5	col-121	F56D5.1	n/a	chrIV 9,395,553	col-121 encodes a cuticle collagen required for resistance to the endocrine disrupting chemical bisphenol A (BPA); col-121(nx3) and col-121(RNAi) animals are hypersensitive to BPA, but are otherwise wild-type (e.g., they have normal body shape); BPA hypersensitivity has also been observed for dpy-2(e8), dpy-7(e88) and dpy-10(e128) mutants.
6	F55C9.3	F55C9.3	n/a	chrV 19,287,274	contains similarity to Pfam domain PF02170 PAZ domain contains similarity to Interpro domain IPR003100 (Argonaute and Dicer protein, PAZ)
7	K02E7.7	K02E7.7	n/a	chrII 1,055,525
8	F58E1.11	F58E1.11	n/a	chrII 1,692,234	contains similarity to Interpro domain IPR002034 (Alpha-isopropylmalate/homocitrate synthase, conserved site)
9	F43G6.5	F43G6.5	n/a	chrII 11,815,623	contains similarity to Pfam domains PF04926 (Poly(A) polymerase predicted RNA binding domain) , PF01909 (Nucleotidyltransferase domain) , PF04928 (Poly(A) polymerase central domain) contains similarity to Interpro domains IPR007012 (Poly(A) polymerase, central region), IPR002934 (Nucleotidyltransferase), IPR007010 (Poly(A) polymerase, RNA-binding region), IPR014492 (Poly(A) polymerase), IPR011068 (Nucleotidyltransferase, class I, C-terminal-like)
10	taf-7.1	F54F7.1	n/a	chrX 11,836,759	The taf-7.1 gene encodes an ortholog of mammalian TATA-binding protein associated factor TAF7L (TAFIIQ, OMIM:300314) that in mice exhibits testis-specific expression; TAF-7 function in C. elegans is not yet known, as taf-7 inactivation by RNA interference does not result in any obvious developmental defects.
11	fbxb-62	F55C9.8	n/a	chrV 19,301,505	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
12	F31D5.6	F31D5.6	n/a	chrII 4,211,553	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
13	T26E3.5	T26E3.5	n/a	chrI 12,663,411	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
14	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
15	F13H10.1	F13H10.1	n/a	chrIV 11,004,784	contains similarity to Oryza sativa Putative pM5 collagenase.; TR:Q93W04
16	T02G5.2	T02G5.2	n/a	chrII 7,095,853	contains similarity to Interpro domains IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR001023 (Heat shock protein Hsp70)
17	mdt-31	F32H2.2	n/a	chrI 8,966,630	C. elegans MDT-31 protein; contains similarity to Pfam domain PF05669 SOH1 contains similarity to Interpro domain IPR008831 (SOH1)
18	fbxb-54	K05F6.7	n/a	chrII 1,555,788	C. elegans FBXB-54 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001404 (Heat shock protein Hsp90), IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
19	Y116A8B.1	Y116A8B.1	n/a	chrIV 17,216,790	contains similarity to Oryza sativa P0660F12.13 protein (P0614D08.10 protein).; TR:Q94CR6
20	C24H12.8	C24H12.8	n/a	chrII 422,729	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
21	Y57A10C.1	Y57A10C.1	n/a	chrII 12,411,984	contains similarity to Macaca mulatta Thyrotropin receptor (Fragment).; TR:Q8HY53
22	T28C6.3	T28C6.3	n/a	chrIV 8,820,742	contains similarity to Homo sapiens HIV Tat-specific factor 1; ENSEMBL:ENSP00000218364
23	ZK899.6	ZK899.6	n/a	chrX 9,463,973	contains similarity to Saccharomyces cerevisiae Delta-like subunit of the yeast AP-3 complex which functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function; SGD:YPL195W
24	T05D4.2	T05D4.2	n/a	chrIII 13,562,369	contains similarity to Mus musculus Similar to SPEER 2.; TR:Q80ZP2
25	Y73C8C.8	Y73C8C.8	n/a	chrV 3,112,017	contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR001965 (Zinc finger, PHD-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR011016 (Zinc finger, variant RING-type)
26	fbxb-25	F58E1.2	n/a	chrII 1,684,456	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
27	nhr-273	T12C9.1	n/a	chrII 4,436,140	C. elegans NHR-273 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
28	ceh-36	C37E2.4	n/a	chrX 14,184,445	ceh-36 encodes a paired-like homeodomain transcription factor that is one of three orthodenticle (OTD)-like homeodomain proteins in C. elegans (the others being ttx-1 and ceh-37); CEH-36 is required broadly for specification of the AWC olfactory neuron and also for establishing the left-right asymmetry of the ASEL and ASER gustatory neurons; in addition, CEH-36 is sufficient to specify the AFD thermosensory neuron fate in some cell types; CEH-36 is expressed in the AWC and ASE chemosensory neurons.
29	dsl-1	W09G12.4	n/a	chrIV 1,207,661	dsl-1 encodes a secreted protein with a single DSL and EGF domain in series, resembling Delta/LAG-2; DSL-1, with APX-1 and LAG-2, is collectively required for LIN-12/Notch-mediated lateral signalling during postembryonic vulval development; DSL-1, when misexpressed by lag-2 sequences, can rescue the larval-lethal and anchor cell phenotypes of lag-2(q420ts); dsl-1(RNAi) animals have abnormal vulvae in a genetic background sensitized for lateral signalling defects; dsl-1(ok810) mutants, while viable and fertile, have a 4% penetrant defect in lateral signaling, which exceeds 13% with apx-1 and lag-2 RNAi; dsl-1 is strongly transcribed in P6.p cells; SUR-2 regulates dsl-1 along with apx-1 and lag-2; DSL-1 belongs to a nematode-specific family of Delta/LAG-2-like proteins that includes DSL-2, -3, -5, -6, and -7.
30	fbxb-32	M151.6	n/a	chrII 3,646,198	C. elegans FBXB-32 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
31	R07C3.6	R07C3.6	n/a	chrII 924,524
32	sdz-18	F45C12.11	n/a	chrII 1,705,740	C. elegans SDZ-18 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00917 (MATH domain) contains similarity to Interpro domains IPR008974 (TRAF-like), IPR002083 (MATH), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
33	fbxb-22	Y56A3A.10	n/a	chrIII 11,882,947	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
34	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
35	K08H2.4	K08H2.4	n/a	chrX 13,239,283
36	R11.4	R11.4	n/a	chrX 16,210,394	contains similarity to Leishmania major Hypothetical protein.; TR:Q9GRL1
37	Y65A5A.3	Y65A5A.3	n/a	chrIV 16,416,285	contains similarity to Human papillomavirus type 13 Probable E4 protein.; SW:VE4_HPV13
38	fbxb-103	F53C3.2	n/a	chrII 3,907,716	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
39	F42A10.6	F42A10.6	n/a	chrIII 6,176,450
40	gpc-2	F08B6.2	n/a	chrI 6,757,967	gpc-2 encodes one of two C. elegans heterotrimeric G protein gamma subunits; gpc-2 is required, along with its partner GPB-1, a G protein beta subunit, for proper mitotic spindle positioning and orientation during early embryonic cell divisions; to date, GPC-2 expression has been reported in electrically excitable cells (all neurons and muscles).
41	dct-13	Y116A8C.17	n/a	chrIV 17,024,680	Y116A8C.17 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of Y116A8C.17 is predicted to function as an RNA-binding protein.
42	F45D3.1	F45D3.1	n/a	chrV 12,527,844	contains similarity to Schizosaccharomyces pombe Hypothetical 92.4 kDa protein C1685.14C in chromosome II.; TR:O74334
43	C35D6.4	C35D6.4	n/a	chrIV 16,351,255	C35D6.4 encodes a CCCH tandem zinc finger (TZF) protein; based upon its sequence similarity to other TZF proteins, such as MEX-5 and POS-1, the product of C35D6.4 is predicted to function as an RNA-binding protein.
44	F40G9.9	F40G9.9	n/a	chrIII 169,417	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
45	F42H10.2	F42H10.2	n/a	chrIII 8,490,759	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domains IPR010625 (CHCH), IPR013032 (EGF-like region, conserved site)
46	Y44A6C.2	Y44A6C.2	n/a	chrV 20,718,374	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8I380
47	srb-7	F37C12.17	n/a	chrIII 7,178,120	C. elegans SRB-7 protein; contains similarity to Pfam domains PF02117 (C.elegans Sra family integral membrane protein) , PF02175 (C.elegans integral membrane protein Srb) contains similarity to Interpro domains IPR001463 (Sodium:alanine symporter), IPR002184 (Serpentine beta receptor), IPR000344 (Nematode chemoreceptor, Sra)
48	F31D4.5	F31D4.5	n/a	chrV 20,851,509	contains similarity to Pfam domain PF00169 PH domain contains similarity to Interpro domains IPR001849 (Pleckstrin-like), IPR010997 (HRDC-like), IPR011993 (Pleckstrin homology-type)
49	ZK418.3	ZK418.3	n/a	chrIII 7,070,514	contains similarity to Homo sapiens Transmembrane protein 17; ENSEMBL:ENSP00000335094
50	fbxb-16	ZC204.10	n/a	chrII 1,651,202	fbxb-16 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXB-16 also contains a C-terminal type 2 F-box-associated domain of presently unknown function.