UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F40D4.13	F40D4.13	3e-164	chrV 17,156,612	contains similarity to Homo sapiens Splice isoform 1 of P45378 Troponin T, fast skeletal muscle isoforms; SW:P45378
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
4	F45H10.2	F45H10.2	n/a	chrII 13,492,421	contains similarity to Pfam domain PF02939 UcrQ family contains similarity to Interpro domain IPR004205 (UcrQ)
5	T10E10.4	T10E10.4	n/a	chrX 6,318,637	T10E10.4 encodes a large (966-residue) protein, predicted to be secreted, with two N-terminal chitin-binding peritrophin-A domains followed by 14 cysteine-rich domains and one C-terminal EB module; the general organization of T10E10.4 protein resembles that of K04H4.2; T10E10.4 has no obvious function in mass RNAi assays but, like CEJ-1 and CPG-2, might participate in chitin synthesis.
6	R03G5.3	R03G5.3	n/a	chrX 7,803,002	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
7	F58A6.1	F58A6.1	n/a	chrII 5,143,154	contains similarity to Pfam domain PF00378 Enoyl-CoA hydratase/isomerase family contains similarity to Interpro domains IPR014748 (Crontonase, C-terminal), IPR001753 (Crotonase, core)
8	K09H11.1	K09H11.1	n/a	chrV 5,749,898	contains similarity to Pfam domains PF08028 (Acyl-CoA dehydrogenase, C-terminal domain) , PF01636 (Phosphotransferase enzyme family) , PF02770 (Acyl-CoA dehydrogenase, middle domain) , PF00441 (Acyl-CoA dehydrogenase, C-terminal domain) , PF00702 (haloacid dehalogenase-like hydrolase) contains similarity to Interpro domains IPR011945 (Predicted HAD-superfamily phosphatase, subfamily IA/Epoxide hydrolase, N-terminal), IPR005833 (Haloacid dehydrogenase/epoxide hydrolase), IPR013107 (Acyl-CoA dehydrogenase, type 2, C-terminal), IPR006090 (Acyl-CoA oxidase/dehydrogenase, type 1), IPR013786 (Acyl-CoA dehydrogenase/oxidase, N-terminal), IPR006091 (Acyl-CoA dehydrogenase/oxidase, central region), IPR011009 (Protein kinase-like), IPR006402 (HAD-superfamily hydrolase, subfamily IA, variant 3), IPR013764 (Acyl-CoA oxidase/dehydrogenase, type1/2, C-terminal), IPR009100 (Acyl-CoA dehydrogenase/oxidase, middle and N-terminal), IPR000169 (Peptidase, cysteine peptidase active site), IPR005834 (Haloacid dehalogenase-like hydrolase), IPR008266 (Tyrosine protein kinase, active site), IPR002575 (Aminoglycoside phosphotransferase)
9	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
10	T20H9.6	T20H9.6	n/a	chrIII 2,247,987	contains similarity to Pfam domain PF02206 Domain of unknown function contains similarity to Interpro domain IPR003125 (Protein of unknown function WSN)
11	F56A12.2	F56A12.2	n/a	chrV 14,377,560	contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
12	C40H5.3	C40H5.3	n/a	chrX 11,760,088	contains similarity to Solanum aggregatum NADH dehydrogenase subunit (Fragment).; TR:Q8HSG2
13	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
14	F45H7.1	F45H7.1	n/a	chrIII 3,346,522	contains similarity to Mus musculus Sphingosine kinase 2 (EC 2.7.1.-) (SK 2) (SPK 2).; SW:SPH2_MOUSE
15	F47G9.3	F47G9.3	n/a	chrV 11,315,117	contains similarity to Pfam domains PF00100 (Zona pellucida-like domain) , PF00024 (PAN domain) (2)contains similarity to Interpro domains IPR003609 (Apple-like), IPR003014 (N/apple PAN), IPR001507 (Endoglin/CD105 antigen)
16	T20D4.6	T20D4.6	n/a	chrV 3,411,676	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR014752 (Arrestin, C-terminal), IPR011021 (Arrestin-like, N-terminal)
17	Y38H6C.13	Y38H6C.13	n/a	chrV 20,523,455	contains similarity to Pfam domain PF00646 F-box domain contains similarity to Interpro domain IPR001810 (Cyclin-like F-box)
18	srh-277	K05D4.6	n/a	chrV 16,186,134	C. elegans SRH-277 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR001280 (Photosystem I psaA and psaB)
19	sbp-1	Y47D3B.7	n/a	chrIII 11,435,265	sbp-1 encodes a basic helix-loop-helix (bHLH) transcription factor homologous to the mammalian Sterol Regulatory Element Binding Proteins (SREBPs, OMIM:184756, overexpression of nuclear form of SREBP-1c is associated with insulin resistance and features of congenital generalized lipodystrophy); in C. elegans, SBP-1 activity is required for normal lipid metabolism and wild-type levels of lipogenic enzyme expression, as well as for embryonic and larval development; sbp-1 expression is detected exclusively in the intestine, the major site of fat storage, from early embryogenesis through adulthood.
20	C54C8.2	C54C8.2	n/a	chrI 12,445,611	contains similarity to Homo sapiens N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase; ENSEMBL:ENSP00000309096
21	srt-22	ZK1037.3	n/a	chrV 15,315,273	C. elegans SRT-22 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
22	odd-1	B0280.4	n/a	chrIII 7,108,745	odd-1 encodes a C2H2-type zinc finger-containing transcription factor similar to Drosophila odd skipped which is required for embryonic patterning; ODD-1 is expressed in the gut during embryogenesis and appears to be essential for larval development.
23	C27A2.4	C27A2.4	n/a	chrII 5,058,455	contains similarity to Pfam domain PF00328 Histidine acid phosphatase contains similarity to Interpro domain IPR000560 (Histidine acid phosphatase)
24	ugt-25	C10H11.3	n/a	chrI 4,733,442	C. elegans UGT-25 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
25	gst-21	ZK697.6	n/a	chrV 1,731,381	C. elegans GST-21 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
26	pxn-1	ZK994.3	n/a	chrV 8,498,505	C. elegans PXN-1 protein; contains similarity to Pfam domains PF07686 (Immunoglobulin V-set domain) , PF00047 (Immunoglobulin domain) (2), PF00560 (Leucine Rich Repeat) (4), PF01462 (Leucine rich repeat N-terminal domain) , PF07679 (Immunoglobulin I-set domain) (2), PF03098 (Animal haem peroxidase) contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR000483 (Cysteine-rich flanking region, C-terminal), IPR001611 (Leucine-rich repeat), IPR013098 (Immunoglobulin I-set), IPR010255 (Haem peroxidase), IPR003596 (Immunoglobulin V-set, subgroup), IPR013783 (Immunoglobulin-like fold), IPR003591 (Leucine-rich repeat, typical subtype), IPR013106 (Immunoglobulin V-set), IPR007110 (Immunoglobulin-like), IPR002007 (Haem peroxidase, animal), IPR000372 (Leucine-rich repeat, cysteine-rich flanking region, N-terminal), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
27	H02F09.3	H02F09.3	n/a	chrX 1,570,762	contains similarity to Interpro domain IPR001757 (ATPase, P-type, K/Mg/Cd/Cu/Zn/Na/Ca/Na/H-transporter)
28	gpdh-1	F47G4.3	n/a	chrI 14,077,014	gpdh-1 encodes one of two C. elegans glycerol 3-phosphate dehydrogenases; although loss of gpdh-1 activity via large-scale RNAi screens results in no obvious defects, gpdh-1 mRNA expression is upregulated in response to hypertonicity, suggesting that GPDH-1 does play a role in osmotic stress adaptation in C. elegans.
29	F59E11.6	F59E11.6	n/a	chrV 8,992,414	contains similarity to Pfam domain PF01579 Domain of unknown function DUF19 contains similarity to Interpro domain IPR002542 (Protein of unknown function DUF19)
30	fbxa-58	C29F9.11	n/a	chrIII 110,182	C. elegans FBXA-58 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domain IPR002900 (Protein of unknown function DUF38, Caenorhabditis species)
31	K09E10.2	K09E10.2	n/a	chrIV 12,309,919	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
32	glb-6	C18C4.9	n/a	chrV 5,569,355	glb-6 encodes a globin that is expressed in neurons, but that has no obvious function in mass RNAi assays; glb-6 expression is downregulated in a daf-2(e1370) mutant background under normoxic conditions.
33	F47F6.3	F47F6.3	n/a	chrII 1,264,985	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
34	Y70C5A.2	Y70C5A.2	n/a	chrV 16,622,275	contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
35	D1014.6	D1014.6	n/a	chrV 8,122,275	contains similarity to Pfam domain PF01697 Domain of unknown function contains similarity to Interpro domain IPR008166 (Protein of unknown function DUF23)
36	W06A7.2	W06A7.2	n/a	chrV 14,822,585	contains similarity to Salmonella typhi;Salmonella typhimurium Hypothetical protein (Putative inner membrane protein).; TR:Q8XEW6
37	C32D5.6	C32D5.6	n/a	chrII 6,332,890	contains similarity to Interpro domain IPR013026 (Tetratricopeptide region)
38	srg-10	T04A8.1	n/a	chrIII 4,678,679	C. elegans SRG-10 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
39	arc-1	ZK1320.6	n/a	chrII 9,676,012	arc-1 encodes a member of the ARL (ADP-ribosylation factor(ARF)-like) family of proteins which are very similar to ARF proteins but lack the ability to stimulate ADP ribosylation by cholera toxin; arc-1 has a human homolog, MID1, which when mutated leads to Opitz syndrome (OMIM:300000).
40	gpa-18	W03F8.9	n/a	chrIV 5,192,340	gpa-18 encodes a divergent G protein alpha subunit, with roughly as much similarity to fungal as to metazoan homologs.
41	ZK899.3	ZK899.3	n/a	chrX 9,454,242	contains similarity to Homo sapiens C10ORF6; ENSEMBL:ENSP00000238961
42	F55A3.6	F55A3.6	n/a	chrI 10,784,384	contains similarity to Pfam domain PF00334 Nucleoside diphosphate kinase contains similarity to Interpro domain IPR001564 (Nucleoside diphosphate kinase, core)
43	K10D11.5	K10D11.5	n/a	chrIV 12,990,724	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site), IPR003366 (CUB-like region)
44	C50H11.8	C50H11.8	n/a	chrV 3,055,230
45	F41D3.11	F41D3.11	n/a	chrI 12,277,794	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
46	H06O01.2	H06O01.2	n/a	chrI 7,012,174	H06O01.2 encodes a large (1,461-aa) putative chromodomain helicase DNA-binding protein that inhibits DHC-1 in vivo; H06O01.2 is orthologous to budding yeast CHD1, human CHD1 (OMIM:602118), and human CHD2 (OMIM:602119); H06O01.2(RNAi) suppresses the lethality of conditional dhc-1 mutations, as well as the spindle length and cytokinesis defects of dhc-1(or195), indicating that H06O01.2 negatively regulates dynein; H06O01.2 has no obvious function in mass RNAi assays.
47	tre-4	F15A2.2	n/a	chrX 13,473,950	C. elegans TRE-4 protein; contains similarity to Pfam domain PF01204 Trehalase contains similarity to Interpro domains IPR001661 (Glycoside hydrolase, family 37), IPR000886 (Endoplasmic reticulum, targeting sequence), IPR008928 (Six-hairpin glycosidase-like)
48	clec-66	F35C5.9	n/a	chrII 12,905,422	C. elegans CLEC-66 protein; contains similarity to Pfam domains PF00092 (von Willebrand factor type A domain) , PF00059 (Lectin C-type domain) contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin), IPR002035 (von Willebrand factor, type A)
49	ech-8	F01G10.2	n/a	chrIV 10,237,849	C. elegans ECH-8 protein; contains similarity to Pfam domains PF00725 (3-hydroxyacyl-CoA dehydrogenase, C-terminal domain) , PF02737 (3-hydroxyacyl-CoA dehydrogenase, NAD binding domain) contains similarity to Interpro domains IPR008927 (6-phosphogluconate dehydrogenase, C-terminal-like), IPR006108 (3-hydroxyacyl-CoA dehydrogenase, C-terminal), IPR013328 (Dehydrogenase, multihelical), IPR006176 (3-hydroxyacyl-CoA dehydrogenase, NAD binding), IPR016040 (NAD(P)-binding)
50	T04F3.1	T04F3.1	n/a	chrV 11,747,105	contains similarity to Pfam domain PF00155 Aminotransferase class I and II contains similarity to Interpro domains IPR001176 (1-aminocyclopropane-1-carboxylate synthase), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR004839 (Aminotransferase, class I and II), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)