UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F40A3.2	F40A3.2	2.9999999999999997e-109	chrV 7,880,134	contains similarity to Interpro domains IPR000742 (EGF-like, type 3), IPR013032 (EGF-like region, conserved site)
2	C50F7.9	C50F7.9	n/a	chrIV 7,731,347
3	ZK1320.9	ZK1320.9	n/a	chrII 9,685,397	contains similarity to Pfam domain PF02550 Acetyl-CoA hydrolase/transferase N-terminal domain contains similarity to Interpro domains IPR003702 (Acetyl-CoA hydrolase/transferase), IPR001220 (Legume lectin, beta domain)
4	F10D11.4	F10D11.4	n/a	chrI 8,441,960	contains similarity to Interpro domain IPR005819 (Histone H5)
5	hmit-1.2	Y51A2D.5	n/a	chrV 18,526,923	hmit-1.2 encodes one of three C. elegans proton (H+)-dependent myo-inositol transporters; loss of hmit-1.2 activity via large-scale RNAi result in no obvious abnormalities but by homology, HMIT-1.2 is predicted to function as a plasma membrane protein required for the regulated uptake of myo-inositol and thus potentially for regulation of cell signaling and intracellular osmolarity.
6	T10D4.1	T10D4.1	n/a	chrII 3,151,352	contains similarity to Pfam domains PF01579 (Domain of unknown function DUF19) , PF02343 (Domain of unknown function DUF130) contains similarity to Interpro domains IPR003326 (Protein of unknown function DUF130), IPR002542 (Protein of unknown function DUF19)
7	nhr-143	F59E11.11	n/a	chrV 8,974,032	C. elegans NHR-143 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
8	rab-11.2	W04G5.2	n/a	chrI 11,633,357	C. elegans RAB-11.2 protein; contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras), IPR006689 (ARF/SAR superfamily)
9	twk-25	M04B2.5	n/a	chrIV 11,507,989	C. elegans TWK-25 protein; contains similarity to Pfam domain PF07885 Ion channel contains similarity to Interpro domains IPR003280 (Potassium channel, two pore-domain), IPR013099 (Ion transport 2), IPR003092 (Potassium channel, two pore-domain, TASK)
10	F16B4.3	F16B4.3	n/a	chrV 1,597,417	contains similarity to Pfam domain PF06918 Protein of unknown function (DUF1280) contains similarity to Interpro domain IPR009689 (Protein of unknown function DUF1280)
11	H05C05.3	H05C05.3	n/a	chrIII 2,967,980
12	F39D8.3	F39D8.3	n/a	chrX 15,423,577	contains similarity to Homo sapiens Sperm-specific thioredoxin; ENSEMBL:ENSP00000304908
13	lin-48	F34D10.5	n/a	chrIII 3,746,355	lin-48 encodes a C2H2-type zinc-finger transcription factor that is orthologous to Drosophila OVO and mouse OVO1; LIN-48 is required for development of the hindgut, the male tail, and the excretory duct cell; in hindgut and male tail development, LIN-48 activity is essential for proper fate specification of the U, F, and K' blast cells and B blast cell descendants, and in excretory duct cell development, for normal duct cell morphogenesis; a LIN-48 translational reporter is expressed in the nuclei of the U, F, K, and K' blast cells, the excretory duct cell, and up to 10 cells in the head region beginning in late embryogenesis and continuing through adulthood; in addition, expression is detected in the neuronal support cells of the phasmid and labial sensory structures beginning at the late L1 larval stage; in hindgut cell specification, LIN-48 functions with EGL-38/Pax, which appears to be a direct transcriptional regulator of LIN-48 expression, and in excretory duct cell development, LIN-48 is likely under the control of the CES-2 bZip transcription factor
14	srx-67	K07C6.10	n/a	chrV 3,917,627	C. elegans SRX-67 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR002651 (Protein of unknown function DUF32)
15	wrt-8	C29F3.2	n/a	chrV 15,343,304	wrt-8 encodes a hedgehog-like protein, with (from N- to C-terminus) a signal sequence, a Wart domain, an short region of low-complexity sequence, and a Hint/Hog domain; WRT-8 is strongly expressed in hypodermal syncytia hyp6-hyp10 throughout life, and in in 12 subventral P cells and their descendants from 3-fold embryo to L2 larva stages; the Hint/Hog domain is predicted to cut WRT-8 into two halves and then covalently link cholesterol to the C-terminus of the Wart domain; the Wart domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins; WRT-8 has no obvious function in RNAi assays.
16	F59F5.1	F59F5.1	n/a	chrX 10,530,779	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
17	fbxa-111	Y102A5C.14	n/a	chrV 16,949,135	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
18	Y40B1B.5	Y40B1B.5	n/a	chrI 13,436,717	contains similarity to Homo sapiens Retinoblastoma binding protein 6 isoform 1; ENSEMBL:ENSP00000317872
19	srh-105	T27A1.7	n/a	chrII 508,784	C. elegans SRH-105 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
20	C34F6.10	C34F6.10	n/a	chrX 11,233,244	contains similarity to Pfam domain PF00041 Fibronectin type III domain contains similarity to Interpro domains IPR008957 (Fibronectin, type III-like fold), IPR003961 (Fibronectin, type III), IPR000694 (Proline-rich region)
21	gtl-2	F54D1.5	n/a	chrIV 11,277,712	gtl-2 encodes a predicted receptor-activated calcium channel and represents a family of calcium channels, the other two family members being gtl-1 and gon-2.
22	F25F8.1	F25F8.1	n/a	chrI 4,890,200	contains similarity to Interpro domain IPR011042 (Six-bladed beta-propeller, TolB-like)
23	abts-2	F52D10.1	n/a	chrX 11,587,609	abts-2 encodes an anion transporter; when expressed in Xenopus oocytes, ABTS-2 does not exhibit detectable transport of chloride, sulfate, or oxolate anions; ABTS-2::GFP fusion proteins are expressed in the larval excretory cell and the adult ovaries, while an abts-2::gfp promoter fusion is seen in only one tail ganglion neuron; in intestinal cells, the ABTS-2::GFP fusion protein localizes to the basolateral membrane.
24	Y45F3A.8	Y45F3A.8	n/a	chrIII 10,591,217	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
25	F02C9.2	F02C9.2	n/a	chrV 3,135,542	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domains IPR005049 (Protein of unknown function DUF288), IPR002972 (Prostaglandin D synthase)
26	C26D10.4	C26D10.4	n/a	chrII 8,331,544	contains similarity to Pfam domains PF08544 (GHMP kinases C terminal) , PF00288 (GHMP kinases N terminal domain) contains similarity to Interpro domains IPR006206 (Mevalonate and galactokinase), IPR001174 (Galactokinase/homoserine kinase), IPR006204 (GHMP kinase), IPR014721 (Ribosomal protein S5 domain 2-type fold), IPR013750 (GHMP kinase, C-terminal)
27	str-111	F10A3.15	n/a	chrV 16,168,531	C. elegans STR-111 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	ugt-61	F39G3.1	n/a	chrV 4,743,888	C. elegans UGT-61 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
29	F54E2.4	F54E2.4	n/a	chrV 2,806,913	contains similarity to Pfam domains PF00047 (Immunoglobulin domain) , PF07679 (Immunoglobulin I-set domain) (3)contains similarity to Interpro domains IPR003598 (Immunoglobulin subtype 2), IPR013098 (Immunoglobulin I-set), IPR009134 (Vascular endothelial growth factor receptor, VEGFR, N-terminal), IPR013783 (Immunoglobulin-like fold), IPR007110 (Immunoglobulin-like), IPR003599 (Immunoglobulin subtype), IPR013151 (Immunoglobulin)
30	M57.1	M57.1	n/a	chrIV 3,536,339	contains similarity to Pfam domain PF04435 Domain of unknown function (DUF545) contains similarity to Interpro domain IPR006570 (SPK)
31	egl-23	Y37A1B.11	n/a	chrIV 14,007,827	egl-23 encodes one of 44 C. elegans TWK (two-P domain K+) potassium channel subunits that contain two pore-forming domains and four transmembrane domains; egl-23 was originally defined by gain-of-function mutations that result in defects in locomotion, egg-laying, and enteric muscle activation; loss of egl-23 function via reversion or RNA-mediated interference (RNAi) does not result in any abnormalities suggesting that EGL-23 may function redundantly with other TWK channels; egl-23 does not, however, interact genetically with the UNC-93 group of TWKs encoded by unc-93, sup-9, and sup-10; the EGL-23 expression pattern is not yet known.
32	R06F6.6	R06F6.6	n/a	chrII 10,807,531	contains similarity to Pfam domain PF00046 Homeobox domain contains similarity to Interpro domains IPR012287 (Homeodomain-related), IPR013847 (POU), IPR001356 (Homeobox), IPR009057 (Homeodomain-like)
33	C24A11.2	C24A11.2	n/a	chrI 5,381,597
34	frm-9	F31B12.3	n/a	chrX 10,817,663	frm-9 encodes a B41/ERM (ezrin/radixin/moesin) domain containing protein.
35	ZK896.4	ZK896.4	n/a	chrIV 12,881,875	contains similarity to Pfam domain PF02408 CUB-like domain contains similarity to Interpro domains IPR000859 (CUB), IPR003366 (CUB-like region)
36	F59F5.3	F59F5.3	n/a	chrX 10,539,693	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related), IPR008266 (Tyrosine protein kinase, active site)
37	sri-18	Y22F5A.2	n/a	chrV 10,259,578	C. elegans SRI-18 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
38	tpi-1	Y17G7B.7	n/a	chrII 12,038,108	tpi-1 encodes a putative triosephosphate isomerase orthologous to human TPI1 (OMIM:190450, mutated in TPI deficiency) and Drosophila WASTED AWAY; despite the severity of TPI mutant phenotypes in humans and Drosophila, TPI-1 has no obvious function in mass RNAi assays.
39	fbxa-57	C29F9.10	n/a	chrIII 106,751	C. elegans FBXA-57 protein; contains similarity to Pfam domains PF01827 (FTH domain) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001986 (3-phosphoshikimate 1-carboxyvinyltransferase, core), IPR002900 (Protein of unknown function DUF38, Caenorhabditis species), IPR001810 (Cyclin-like F-box)
40	C49A9.6	C49A9.6	n/a	chrIV 6,212,029	contains similarity to Pfam domain PF03312 Protein of unknown function, DUF272 contains similarity to Interpro domain IPR004987 (Protein of unknown function DUF272)
41	nas-29	F58A6.4	n/a	chrII 5,140,235	C. elegans NAS-29 protein; contains similarity to Pfam domains PF00431 (CUB domain) , PF01400 (Astacin (Peptidase family M12A)) contains similarity to Interpro domains IPR017050 (Peptidase M12A, astacin, nematode), IPR006025 (Peptidase M, neutral zinc metallopeptidases, zinc-binding site), IPR001506 (Peptidase M12A, astacin), IPR006026 (Peptidase, metallopeptidases), IPR000859 (CUB), IPR013032 (EGF-like region, conserved site)
42	F56F11.2	F56F11.2	n/a	chrIII 2,883,625
43	D1007.3	D1007.3	n/a	chrI 4,576,495
44	F42G8.7	F42G8.7	n/a	chrIV 8,127,262	contains similarity to Pfam domain PF00085 Thioredoxin contains similarity to Interpro domains IPR001763 (Rhodanese-like), IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR013766 (Thioredoxin domain)
45	W04H10.1	W04H10.1	n/a	chrII 609,207
46	mab-10	R166.1	n/a	chrII 10,532,058	C. elegans MAB-10 protein; contains similarity to Pfam domains PF04905 (NAB conserved region 2 (NCD2)) , PF04904 (NAB conserved region 1 (NCD1)) contains similarity to Interpro domains IPR010993 (Sterile alpha motif homology), IPR006988 (Nab, N-terminal), IPR006989 (Nab, central region)
47	F15E11.4	F15E11.4	n/a	chrV 2,340,462	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
48	C41C4.3	C41C4.3	n/a	chrII 8,110,504	contains similarity to Pfam domain PF00560 Leucine Rich Repeat contains similarity to Interpro domains IPR001611 (Leucine-rich repeat), IPR003591 (Leucine-rich repeat, typical subtype)
49	F40A3.7	F40A3.7	n/a	chrV 7,897,725	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
50	ire-1	C41C4.4	n/a	chrII 8,118,482	ire-1 encodes a transmembrane serine/threonine protein kinase and site-specific endoribonuclease orthologous to Saccharomyces cerevisiae inositol-requiring 1 protein kinase (Ire1) and human endoplasmic reticulum-to-nucleus signaling 1 (ERN1, OMIM:604033); IRE-1 is required for the unfolded protein response (UPR) that counteracts cellular stress induced by accumulation of unfolded proteins in the endoplasmic reticulum (ER); in response to ER stress, IRE-1 cleaves xbp-1 mRNA to produce transcriptionally active XBP-1 that positively regulates UPR gene expression in order to maintain ER homeostasis.