UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F39F10.4	F39F10.4	2e-49	chrX 16,903,278
2	bbs-2	F20D12.3	n/a	chrIV 7,935,876	bbs-2 is orthologous to human BBS2 (OMIM:606151, mutated in Bardet-Biedl syndrome 2); while the function of BBS-2 is unknown, it shares conserved domains with its human paralogs BBS1 and BBS7, which also are mutated in other Bardet-Biedl syndromes.
3	EEED8.2	EEED8.2	n/a	chrII 5,417,509	contains similarity to Interpro domains IPR012674 (Calycin), IPR011038 (Calycin-like), IPR000463 (Cytosolic fatty-acid binding)
4	F46F5.14	F46F5.14	n/a	chrII 800,774	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
5	unc-42	F58E6.10	n/a	chrV 9,766,975	unc-42 encodes a paired-like homeodomain protein of the Q50 class; UNC-42 is required to specify the fate of ASH sensory neurons, AVA, AVD, and AVE interneurons, and a subset of motor neurons; unc-42 mutants fail to express cell-surface receptors required for differentiated neuronal function (sra-6, srb-6, glr-1, glr-5, and glr-6); UNC-42 is also required for AVKR and HSNL growth cones to follow the PVPR and PVQL pioneer axons, for axonal outgrowth in the backward command interneurons AVA, AVD, and AVE, and for inhibition of ectopic FMRFamide-positive and GABAergic axons; unc-42 mutants are defective in mechanosensation, backward motion, and regulation of egg-laying.
6	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
7	fbxb-24	Y56A3A.15	n/a	chrIII 11,909,309	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
8	fbxb-22	Y56A3A.10	n/a	chrIII 11,882,947	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
9	fbxb-10	T08E11.6	n/a	chrII 1,817,843	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
10	R07C3.11	R07C3.11	n/a	chrII 908,164
11	K02E7.7	K02E7.7	n/a	chrII 1,055,525
12	T26C12.3	T26C12.3	n/a	chrIV 3,273,332	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR013753 (Ras)
13	W10D9.1	W10D9.1	n/a	chrII 454,887
14	F42H10.2	F42H10.2	n/a	chrIII 8,490,759	contains similarity to Pfam domain PF06747 CHCH domain contains similarity to Interpro domains IPR010625 (CHCH), IPR013032 (EGF-like region, conserved site)
15	fbxb-18	F58E1.8	n/a	chrII 1,686,936	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains leucine-rich repeats.
16	fbxb-32	M151.6	n/a	chrII 3,646,198	C. elegans FBXB-32 protein; contains similarity to Pfam domain PF07735 F-box associated contains similarity to Interpro domain IPR012885 (F-box associated type 2)
17	srg-23	Y25C1A.11	n/a	chrII 3,095,026	C. elegans SRG-23 protein; contains similarity to Pfam domain PF02118 C.elegans Srg family integral membrane protein contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
18	ZK418.3	ZK418.3	n/a	chrIII 7,070,514	contains similarity to Homo sapiens Transmembrane protein 17; ENSEMBL:ENSP00000335094
19	F38A5.7	F38A5.7	n/a	chrIV 6,602,016
20	fbxb-81	T17A3.3	n/a	chrIII 140,425	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
21	C41H7.2	C41H7.2	n/a	chrII 3,015,393	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
22	cki-1	T05A6.1	n/a	chrII 7,811,601	cki-1 encodes a homolog of the mammalian cyclin-dependent kinase inhibitor p27/KIP1 that is required for the arrest of cell division in larval blast lineages, dauer larvae and starved L1 larvae; excess CKI-1 expression prematurely stops cell division while cki-1(RNAi) induces extra cell divisions, indicating that CKI-1 quantitatively regulates the amount of mitosis in postembryonic worms.
23	C24H12.1	C24H12.1	n/a	chrII 444,212	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; its encoded protein also contains a Pfam-B45 motif of presently unknown function.
24	W04H10.2	W04H10.2	n/a	chrII 606,109
25	ceh-39	T26C11.7	n/a	chrX 1,855,047	ceh-39 encodes a a ONECUT class CUT homeobox protein with a single N-terminal cut domain; CEH-39 acts as an X-signal element (XSE) to affect sex determination; the cut domain may be a compact DNA-binding domain composed of alpha helices; ceh-39 is one of three nematode-specific ONECUT genes in a cluster with ceh-21 and ceh-41.
26	M106.2	M106.2	n/a	chrII 10,847,185	contains similarity to Homo sapiens Lamin B2; ENSEMBL:ENSP00000264564
27	unc-119	M142.1	n/a	chrIII 10,907,547	unc-119 encodes a novel protein that is highly conserved amongst metazoans; unc-119 activity is required for proper development of the nervous system, including axonal branching and fasciculation, and hence, for normal movement, chemosensation, and feeding; unc-119 is expressed pan-neuronally beginning in the early embryo (~60 cells) and continuing through adulthood; although the molecular function of UNC-119 is not yet known, human UNC119, which can rescue C. elegans unc-119 mutant animals, is reported to function as a receptor-associated activator of signal transduction; thus, UNC-119 may be part of a signal transduction pathway that mediates axonal patterning in response to external developmental cues.
28	C31H5.6	C31H5.6	n/a	chrI 9,045,096	contains similarity to Pfam domains PF08840 (BAAT / Acyl-CoA thioester hydrolase C terminal) , PF04775 (Acyl-CoA thioester hydrolase / Bile acid-CoA amino acid N-acetyltransferase) contains similarity to Interpro domains IPR006862 (Acyl-CoA thioester hydrolase/bile acid-CoA amino acid N-acetyltransferase), IPR014940 (BAAT/Acyl-CoA thioester hydrolase C-terminal), IPR016662 (Acyl-CoA thioesterase, long chain)
29	Y57A10C.1	Y57A10C.1	n/a	chrII 12,411,984	contains similarity to Macaca mulatta Thyrotropin receptor (Fragment).; TR:Q8HY53
30	T23F11.4	T23F11.4	n/a	chrIII 4,664,270	contains similarity to Interpro domain IPR007087 (Zinc finger, C2H2-type)
31	C35E7.3	C35E7.3	n/a	chrI 10,837,920
32	sdz-16	F31E9.4	n/a	chrV 17,327,178	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
33	F58E1.10	F58E1.10	n/a	chrII 1,690,389
34	F26D2.13	F26D2.13	n/a	chrV 16,435,139	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
35	ceh-43	C28A5.4	n/a	chrIII 4,448,260	A homeobox protein of the Distal-less (Dll) class that is required for development of the anterior hypdermis during embryonic morphogenesis for cell adhesion; also affects embryonic and larval viability; it is predominantly expressed in the head hypdodermis, neuronal support cells and CAN neurons.
36	F34D6.1	F34D6.1	n/a	chrII 2,680,190	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
37	C43H6.3	C43H6.3	n/a	chrX 2,408,512	contains similarity to Pfam domain PF00023 Ankyrin repeat contains similarity to Interpro domain IPR002110 (Ankyrin)
38	K02E10.1	K02E10.1	n/a	chrX 2,498,552	contains similarity to Pfam domains PF00071 (Ras family) , PF08477 (Miro-like protein) contains similarity to Interpro domains IPR002041 (Ran GTPase), IPR003577 (Ras small GTPase, Ras type), IPR013684 (Miro-like), IPR003578 (Ras small GTPase, Rho type), IPR005225 (Small GTP-binding protein), IPR001806 (Ras GTPase), IPR003579 (Ras small GTPase, Rab type), IPR006688 (ADP-ribosylation factor), IPR013753 (Ras)
39	ceh-13	R13A5.5	n/a	chrIII 7,556,858	a homolog of Hox genes of labial/Hox1 type; affects viability, body shape and anterior patterning during embryogenesis, interacts genetically with hox genes; and is expressed in A, D, E and MS lineages in the early embryo, and in the anterior dorsal hypodermal cells, anterior body wall muscle cells, and in the cells of the prospective ventral nerve cord at the comma stage; and in the ventral nerve cord and and ventral and dorsal hypodermal cells in L1 larvae.
40	ZK673.5	ZK673.5	n/a	chrII 10,461,630	contains similarity to Interpro domain IPR001621 (Fungal lignin peroxidase)
41	ZK938.2	ZK938.2	n/a	chrII 9,837,617	contains similarity to Pfam domains PF00339 (Arrestin (or S-antigen), N-terminal domain) , PF02752 (Arrestin (or S-antigen), C-terminal domain) contains similarity to Interpro domains IPR014756 (Immunoglobulin E-set), IPR011022 (Arrestin-like, C-terminal), IPR011021 (Arrestin-like, N-terminal)
42	fbxb-66	Y40B1B.3	n/a	chrI 13,424,575	C. elegans FBXB-66 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
43	C05D12.5	C05D12.5	n/a	chrII 11,434,516	contains similarity to Homo sapiens Isoform 1 of Cingulin-like protein 1; ENSEMBL:ENSP00000281282
44	fbxb-101	Y63D3A.3	n/a	chrI 14,088,963	C. elegans FBXB-101 protein; contains similarity to Pfam domains PF07735 (F-box associated) , PF00646 (F-box domain) contains similarity to Interpro domains IPR001810 (Cyclin-like F-box), IPR012885 (F-box associated type 2)
45	inx-6	C36H8.2	n/a	chrIV 12,748,113	inx-6 encodes an innexin, an integral transmembrane channel protein that is a structural component of invertebrate gap junctions; INX-6 is required for formation of pharyngeal gap junctions and thus for the electrical coupling and synchronous muscle contractions necessary for normal feeding behavior and postembryonic development; INX-6 may function redundantly with EAT-5, another C. elegans innexin; INX-6 expression is first detected in embryonic pharyngeal precursors and during later larval and adult stages, in pharyngeal corpus muscles and isthmus marginal cells, where INX-6 localizes to plaque-like structures in the plasma membrane.
46	let-381	F26B1.7	n/a	chrI 6,322,210	let-381 encodes a forkhead transcription factor and was identified in a screen for essential genes; let-381 is essential for development at different times as mutants exhibit embryonic and early larval lethality, with a few developing to sterile adults; inactivation of let-381 using RNA interference results in adults with mesodermal cell lineage defects and a reduced number of coelomocytes; reporter-gene assays indicate LET-318 is expressed when the embryo starts to elongate and continues to be expressed through all larval stages and into the adult.
47	fbxb-17	F58E1.5	n/a	chrII 1,676,856	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins.
48	srw-144	H05B21.4	n/a	chrV 2,960,090	C. elegans SRW-144 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
49	ugt-56	T04H1.8	n/a	chrV 12,260,070	C. elegans UGT-56 protein; contains similarity to Pfam domain PF00201 UDP-glucoronosyl and UDP-glucosyl transferase contains similarity to Interpro domain IPR002213 (UDP-glucuronosyl/UDP-glucosyltransferase)
50	F14B4.1	F14B4.1	n/a	chrI 9,268,427	contains similarity to Pfam domains PF00008 (EGF-like domain) (2), PF07645 (Calcium binding EGF domain) , PF00057 (Low-density lipoprotein receptor domain class A) , PF00058 (Low-density lipoprotein receptor repeat class B) (4)contains similarity to Interpro domains IPR000033 (), IPR006209 (EGF-like), IPR000152 (Aspartic acid and asparagine hydroxylation site), IPR006210 (EGF), IPR002172 (Low density lipoprotein-receptor, class A, cysteine-rich), IPR001881 (EGF-like calcium-binding), IPR011042 (Six-bladed beta-propeller, TolB-like), IPR013032 (EGF-like region, conserved site), IPR013091 (EGF calcium-binding), IPR015943 (WD40/YVTN repeat-like)