UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F35H8.1	F35H8.1	1.9999999999999998e-87	chrII 9,552,878	contains similarity to Plasmodium falciparum Hypothetical protein.; TR:Q8ILJ6
2	bra-2	F23H11.1	n/a	chrIII 911,744	The bra-2 gene encodes a homolog of the human BMP receptor-associated molecule (BRAM1), paralogous to bra-1, that may act upon the SMA-6 TGF-beta signalling pathway
3	clec-79	F47C12.4	n/a	chrIV 3,974,525	C. elegans CLEC-79 protein; contains similarity to Pfam domain PF00059 Lectin C-type domain contains similarity to Interpro domains IPR000538 (Link), IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
4	mab-9	T27A1.6	n/a	chrII 518,813	mab-9 encodes a member of the T-box family of transcriptional regulators containing a 200-amino acid T-box DNA-binding domain most similar to mouse Brachyury; mab-9 is involved in hindgut and male tail development, specifically affecting the fate of two posterior blast cells in the hindgut, B and F; in the male this results in a grossly abnormal tail lacking spicules, and renders them incapable of mating; in the hermaphrodite this results in hindgut defects; mab-9 may also be part of a network of T-box genes that includes tbx-8, tbx-9 and vab-7 and is important for the correct patterning of posterior cells in the developing embryo; mab-9 affects movement to some extent though the basis for this defect is unknown; MAB-9 localizes to the nucleus of B and F and their descendents during development.
5	nspa-1	H12D21.1	n/a	chrV 14,886,813	C. elegans NSPA-1 protein ;
6	B0273.1	B0273.1	n/a	chrIV 5,494,609
7	F36A4.4	F36A4.4	n/a	chrIV 4,267,908	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
8	F37A8.1	F37A8.1	n/a	chrIII 3,928,769	contains similarity to Rattus norvegicus Myotonic dystrophy kinase-related Cdc42-binding kinase MRCK-beta.; TR:O54875
9	F36A4.2	F36A4.2	n/a	chrIV 4,271,510	contains similarity to Pfam domain PF05912 Caenorhabditis elegans protein of unknown function (DUF870) contains similarity to Interpro domain IPR008588 (Protein of unknown function DUF870, Caenorhabditis species)
10	lact-2	ZK945.1	n/a	chrII 10,096,751	lact-2 encodes a beta-lactamase domain-containing protein that contains a predicted transmembrane domain in its N terminus.
11	T25B9.6	T25B9.6	n/a	chrIV 10,759,435	contains similarity to Interpro domain IPR006162 (Phosphopantetheine attachment site)
12	fat-5	W06D12.3	n/a	chrV 17,725,852	fat-5 encodes a delta-9 fatty acid desaturase that is predicted to be mitochondrial; when expressed heterologously in S. cerevisiae, FAT-5 rescues the fatty acid auxotrophy of the yeast delta-9 desaturase mutant ole1.
13	nspa-8	W06A7.5	n/a	chrV 14,826,947	C. elegans NSPA-8 protein ;
14	Y6E2A.8	Y6E2A.8	n/a	chrV 15,725,749	contains similarity to Encephalitozoon cuniculi UPF0329 protein ECU05_1680/ECU11_0050.; SW:Q8STA9
15	ssp-11	T28H11.6	n/a	chrIV 4,999,632	C. elegans SSP-11 protein; contains similarity to Pfam domain PF00635 MSP (Major sperm protein) domain contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
16	nlp-2	T24D8.5	n/a	chrX 2,344,350	C. elegans NLP-2 protein ;
17	hdl-1	ZK829.2	n/a	chrIV 11,947,905	C. elegans HDL-1 protein; contains similarity to Pfam domain PF00282 Pyridoxal-dependent decarboxylase conserved domain contains similarity to Interpro domains IPR002129 (Pyridoxal phosphate-dependent decarboxylase), IPR010977 (Aromatic-L-amino-acid decarboxylase), IPR015422 (Pyridoxal phosphate-dependent transferase, major region, subdomain 2), IPR015424 (Pyridoxal phosphate-dependent transferase, major region), IPR015421 (Pyridoxal phosphate-dependent transferase, major region, subdomain 1)
18	W03D8.9	W03D8.9	n/a	chrI 2,785,349	contains similarity to Pfam domain PF05884 Caenorhabditis elegans protein of unknown function (DUF856) contains similarity to Interpro domains IPR001991 (Sodium:dicarboxylate symporter), IPR008574 (Protein of unknown function DUF856, Caenorhabditis species)
19	msp-32	R05F9.3	n/a	chrII 4,898,889	msp-32 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; msp-32 has a C. briggsae homolog as predicted by the Wobble Aware Bulk Aligner (WABA); the msp family consists of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSPs are involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSPs assemble into fibrous networks that drive movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
20	K12D9.12	K12D9.12	n/a	chrV 3,021,212	contains similarity to Pfam domain PF01030 Receptor L domain contains similarity to Interpro domain IPR000494 (EGF receptor, L domain)
21	R13H9.5	R13H9.5	n/a	chrIV 5,066,321	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
22	ins-7	ZK1251.2	n/a	chrIV 9,682,219	ins-7 encodes an insulin/IGF-1-like peptide; INS-7 is one of 40 insulin-like peptides in C. elegans; INS-7 likely functions as an agonist for the DAF-2 insulin/IGF-1 receptor, as loss of ins-7 activity via RNAi results in: 1) a significantly increased lifespan that is not further extended in long-lived daf-2 mutant animals, and 2) an increased frequency of dauer formation in animals containing an incompletely penetrant daf-2 mutation; an ins-7 promoter fusion is expressed in amphid sensory neurons, labial neurons, the nerve ring, and ventral cord and tail neurons; ins-7 expression is positively regulated by DAF-2-mediated insulin signaling, suggesting that a positive feedback loop involving INS-7 may amplify DAF-2 pathway activity.
23	ZK666.8	ZK666.8	n/a	chrII 10,492,235	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
24	W01B6.6	W01B6.6	n/a	chrIV 10,081,890	contains similarity to Pfam domain PF00102 Protein-tyrosine phosphatase contains similarity to Interpro domains IPR003595 (Protein-tyrosine phosphatase, catalytic), IPR000242 (Protein-tyrosine phosphatase, receptor/non-receptor type), IPR000387 (Protein-tyrosine phosphatase)
25	gst-9	R05F9.5	n/a	chrII 4,892,523	gst-9 encodes a predicted glutathione S-transferase; by homology, GST-9 is predicted to play a role in the detoxification of environmental toxins and xenobiotics by transferring glutathione to reactive electrophilic compounds; however, as loss of gst-9 activity via large-scale RNAi screens does not result in any obvious abnormalities, the precise role of GST-9 in C. elegans development and/or behavior is not yet known.
26	T05C12.1	T05C12.1	n/a	chrII 8,174,196	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
27	nspa-3	ZC412.7	n/a	chrV 14,880,465	C. elegans NSPA-3 protein ;
28	B0207.5	B0207.5	n/a	chrI 5,927,603
29	F47D12.7	F47D12.7	n/a	chrIII 6,294,525	contains similarity to Pfam domains PF01344 (Kelch motif) (5), PF00651 (BTB/POZ domain) , PF07646 (Kelch motif) contains similarity to Interpro domains IPR011043 (Galactose oxidase/kelch, beta-propeller), IPR000210 (BTB/POZ-like), IPR006652 (Kelch repeat type 1), IPR011333 (BTB/POZ fold), IPR011498 (Kelch repeat type 2), IPR015916 (Galactose oxidase, beta-propeller), IPR013069 (BTB/POZ), IPR013089 (Kelch related), IPR006651 (Kelch), IPR015915 (Kelch-type beta propeller)
30	C10G11.1	C10G11.1	n/a	chrI 6,307,930
31	ncx-8	C13D9.7	n/a	chrV 4,985,459	ncx-8 encodes a putative Na[+]/Ca[2+] exchanger of uncertain stoichiometry and affinity, orthologous to human SLC24A6 and paralogous to NCX-6/-7 and NCX-9/-10; NCX-8 may function intracellularly; NCX-8 has tandem Calx-alpha domains predicted to carry out ion transport; NCX-8 is required for normally high levels of body fat.
32	C49H3.3	C49H3.3	n/a	chrIV 7,924,622	contains similarity to Xenopus tropicalis UPF0446 protein C12orf31 homolog.; SW:Q6NVR5
33	dct-9	W03F11.3	n/a	chrI 2,234,343	C. elegans DCT-9 protein; contains similarity to Interpro domains IPR008962 (PapD-like), IPR000535 (Major sperm protein)
34	C13G5.2	C13G5.2	n/a	chrIII 8,617,549	contains similarity to Interpro domain IPR001680 (WD40 repeat)
35	C09B9.2	C09B9.2	n/a	chrIV 5,030,143
36	abt-5	Y53C10A.9	n/a	chrI 12,014,962	abt-5 encodes a predicted ATP-binding cassette (ABC) transporter that is a member of the ABCA subfamily of transport proteins; ABT-5 is predicted to function as a transmembrane protein that couples energy to transport of various molecules across membranes, but as loss of abt-5 activity via RNAi results in no obvious defects, the precise role of abt-5 in C. elegans development and/or behavior is not yet known; abt-5 promoter-gfp fusion proteins are expressed in larvae and adults in the intestine and in unidentified cells in the head.
37	F46F5.9	F46F5.9	n/a	chrII 822,679	contains similarity to Interpro domain IPR000104 (Antifreeze protein, type I)
38	H12D21.2	H12D21.2	n/a	chrV 14,888,059	contains similarity to Tetrahymena thermophila Micronuclear linker histone polyprotein (MIC LH) [Contains:sMicronuclear linker histone-alpha; Micronuclear linker histone-beta;sMicronuclear linker histone-delta; Micronuclear linker histone-gamma].; SW:P40631
39	M7.7	M7.7	n/a	chrIV 11,090,870	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
40	Y51A2B.1	Y51A2B.1	n/a	chrV 18,373,264	contains similarity to Pfam domain PF08719 Domain of unknown function (DUF1768) contains similarity to Interpro domains IPR012816 (Conserved hypothetical protein CHP02464), IPR016160 (Aldehyde dehydrogenase, conserved site)
41	nspa-5	ZC412.6	n/a	chrV 14,878,391	C. elegans NSPA-5 protein ;
42	C41G7.6	C41G7.6	n/a	chrI 9,526,981	contains similarity to Paramecium tetraurelia Chromosome undetermined scaffold_96, whole genome shotgun sequence.; TR:A0EH68
43	T08H10.4	T08H10.4	n/a	chrV 4,480,975	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
44	ZK1128.3	ZK1128.3	n/a	chrIII 10,117,815	contains similarity to Mus musculus 2410017P07Rik protein.; TR:Q9CZE0
45	far-3	F15B9.1	n/a	chrV 12,997,151	C. elegans FAR-3 protein; contains similarity to Pfam domain PF05823 Nematode fatty acid retinoid binding protein (Gp-FAR-1) contains similarity to Interpro domain IPR008632 (Nematode fatty acid retinoid binding)
46	T05C12.3	T05C12.3	n/a	chrII 8,172,837	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR003560 (2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase), IPR002347 (Glucose/ribitol dehydrogenase), IPR000565 (DNA topoisomerase, type IIA, subunit B), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
47	F42G4.6	F42G4.6	n/a	chrII 13,079,994	F42G4.6 encodes a nematode-specific sperm protein; F42G4.6 has no obvious non-nematode homologs, but does have a putative central coiled-coil domain, and is is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, T08G11.2, and Y81G3A.1); F42G4.6(RNAi) animals exhibit aldicarb resistance; F42G4.6 expression is enriched in spermatogenesis.
48	Y81G3A.1	Y81G3A.1	n/a	chrII 13,082,998	Y81G3A.1 encodes a nematode-specific sperm protein; Y81G3A.1 has no obvious non-nematode homologs, but does have a putative central coiled-coil domain, and is is paralogous to four other C. elegans proteins (B0207.11, F42G4.6, F44F4.10, and T08G11.2); Y81G3A.1(RNAi) animals exhibit aldicarb resistance; Y81G3A.1 expression is enriched in spermatogenesis.
49	F13E9.5	F13E9.5	n/a	chrIV 10,883,638	contains similarity to Helicobacter pylori;Helicobacter pylori J99 Hypothetical protein HP0031/JHP0027.; SW:Y031_HELPY
50	Y54E2A.9	Y54E2A.9	n/a	chrII 14,785,517	contains similarity to Pfam domain PF03762 Vitelline membrane outer layer protein I (VOMI) contains similarity to Interpro domain IPR005515 (Vitelline membrane outer layer protein I (VOMI))