UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F35H12.1	F35H12.1	0	chrX 936,580	contains similarity to Interpro domain IPR015649 (Schwannomin interacting protein 1)
2	gst-40	F56B3.10	n/a	chrIV 761,476	C. elegans GST-40 protein; contains similarity to Pfam domains PF00043 (Glutathione S-transferase, C-terminal domain) , PF02798 (Glutathione S-transferase, N-terminal domain) contains similarity to Interpro domains IPR012336 (Thioredoxin-like fold), IPR012335 (Thioredoxin fold), IPR004046 (Glutathione S-transferase, C-terminal), IPR004045 (Glutathione S-transferase, N-terminal), IPR010987 (Glutathione S-transferase, C-terminal-like)
3	nhr-7	F54D1.4	n/a	chrIV 11,267,544	C. elegans NHR-7 protein; contains similarity to Pfam domain PF00105 Zinc finger, C4 type (two domains) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000694 (Proline-rich region), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
4	skr-9	C52D10.7	n/a	chrIV 17,163,837	skr-9 encodes a homolog of Skp1 in S. cerevisiae, a component of the SCF (Skp1, Cullin, F-box) ubiquitin-ligase complex that regulates ubiquitin-mediated protein degradation; SKR-9 is required for posterior body morphogenesis, embryonic and larval development, and postembryonic cell proliferation.
5	C29F9.5	C29F9.5	n/a	chrIII 118,236	contains similarity to Pfam domain PF02135 TAZ zinc finger contains similarity to Interpro domains IPR003101 (Coactivator CBP, KIX), IPR000197 (Zinc finger, TAZ-type)
6	F35E8.1	F35E8.1	n/a	chrV 15,904,615	contains similarity to Pfam domain PF01549 ShK domain-like contains similarity to Interpro domain IPR003582 (Metridin-like ShK toxin)
7	C12D5.9	C12D5.9	n/a	chrV 7,689,147	contains similarity to Pfam domain PF03236 Domain of unknown function DUF263 contains similarity to Interpro domain IPR004920 (Protein of unknown function DUF263)
8	ceh-6	K02B12.1	n/a	chrI 8,500,257	ceh-6 encodes a POU family homeodomain protein, homologous to human POU3F4 (OMIM:304400, mutated in conductive deafness 3) that affects embryonic viability, locomotion, and molting, and that regulates ectodermal and excretory function; CEH-6 is expressed dynamically during development and expression includes neurons, the excretory cell, and ectodermal cells.
9	Y113G7B.11	Y113G7B.11	n/a	chrV 20,209,977	contains similarity to Naja atra Cardiotoxin 10 precursor.; TR:Q9W6W6
10	F54D12.7	F54D12.7	n/a	chrII 1,383,599	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
11	cho-1	C48D1.3	n/a	chrIV 13,212,115	cho-1 encodes a high-affinity choline transporter orthologous to members of the sodium-dependent glucose transporter family; CHO-1 is expressed in cholinergic neurons.
12	F28C10.4	F28C10.4	n/a	chrX 539,044
13	ZK180.2	ZK180.2	n/a	chrIV 4,504,345	contains similarity to Pfam domain PF01094 Receptor family ligand binding region contains similarity to Interpro domains IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B), IPR001828 (Extracellular ligand-binding receptor), IPR000923 (Blue (type 1) copper domain)
14	K08D9.4	K08D9.4	n/a	chrV 3,199,601	contains similarity to Pfam domain PF06342 Alpha/beta hydrolase of unknown function (DUF1057) contains similarity to Interpro domains IPR008262 (Lipase, active site), IPR010463 (Protein of unknown function DUF1057, lipase putative), IPR003089 (Alpha/beta hydrolase)
15	sri-36	F33H12.5	n/a	chrII 2,584,688	C. elegans SRI-36 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
16	Y47H9B.2	Y47H9B.2	n/a	chrI 11,745,783	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domain IPR005514 (Protein of unknown function DUF316)
17	nhr-120	C25B8.6	n/a	chrX 6,638,552	C. elegans NHR-120 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR001723 (Steroid hormone receptor), IPR000324 (Vitamin D receptor), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
18	R13A5.9	R13A5.9	n/a	chrIII 7,577,267	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR001958 (Tetracycline resistance protein, TetA), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
19	F46F5.4	F46F5.4	n/a	chrII 805,580	contains similarity to Pfam domain PF03314 Protein of unknown function, DUF273 contains similarity to Interpro domain IPR004988 (Protein of unknown function DUF273)
20	F40G9.14	F40G9.14	n/a	chrIII 176,962	contains similarity to Pfam domain PF00097 Zinc finger, C3HC4 type (RING finger) contains similarity to Interpro domains IPR001841 (Zinc finger, RING-type), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR007087 (Zinc finger, C2H2-type)
21	Y47H9A.1	Y47H9A.1	n/a	chrI 11,624,828	contains similarity to Pfam domain PF04721 Domain of unknown function (DUF750) contains similarity to Interpro domain IPR006588 (Protein of unknown function PAW)
22	R13A1.5	R13A1.5	n/a	chrIV 7,191,489
23	Y113G7B.15	Y113G7B.15	n/a	chrV 20,226,741	contains similarity to Pfam domains PF08246 (Cathepsin propeptide inhibitor domain (I29)) , PF00112 (Papain family cysteine protease) contains similarity to Interpro domains IPR013128 (Peptidase C1A, papain), IPR000169 (Peptidase, cysteine peptidase active site), IPR013201 (Proteinase inhibitor I29, cathepsin propeptide), IPR000668 (Peptidase C1A, papain C-terminal)
24	Y41C4A.11	Y41C4A.11	n/a	chrIII 11,721,632	Y41C4A.11 encodes a divergent paralog of F38E11.5, the beta' (beta-prime) subunit of the coatomer (COPI) complex; unlike F38E11.5, Y41C4A.11 has no obvious function in mass RNAi assays.
25	clec-154	F10F2.5	n/a	chrIII 4,639,461	C. elegans CLEC-154 protein; contains similarity to Interpro domains IPR016187 (C-type lectin fold), IPR016186 (C-type lectin-like), IPR001304 (C-type lectin)
26	F08D12.2	F08D12.2	n/a	chrII 2,782,368	contains similarity to Pfam domain PF04942 CC domain contains similarity to Interpro domain IPR007026 (Domian of unknown function, DUF-CC)
27	C31H1.2	C31H1.2	n/a	chrIV 5,792,361	contains similarity to Pfam domain PF02013 Cellulose or protein binding domain contains similarity to Interpro domains IPR003616 (Post-SET zinc-binding region), IPR000215 (Protease inhibitor I4, serpin), IPR002883 (Dockerin, cellulose-binding family V)
28	ZC404.7	ZC404.7	n/a	chrV 6,779,108
29	T22B2.7	T22B2.7	n/a	chrX 3,909,459
30	ZK418.6	ZK418.6	n/a	chrIII 7,076,490	contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000694 (Proline-rich region), IPR000276 (GPCR, rhodopsin-like)
31	bath-25	T27C10.4	n/a	chrI 10,877,883	C. elegans BATH-25 protein; contains similarity to Pfam domains PF00651 (BTB/POZ domain) , PF00036 (EF hand) (2), PF00917 (MATH domain) contains similarity to Interpro domains IPR002083 (MATH), IPR011992 (EF-Hand type), IPR002048 (Calcium-binding EF-hand), IPR003299 (Flagellar calcium-binding protein (calflagin)), IPR000210 (BTB/POZ-like), IPR011333 (BTB/POZ fold), IPR013069 (BTB/POZ)
32	ndx-2	W02G9.1	n/a	chrV 2,664,041	ndx-2 encodes a NUDIX hydrolase; by sequence comparison, NDX-2 is predicted to be orthologous to human NUDT5 which, in vitro, possesses ADP-sugar diphosphatase activity; in C. elegans, loss of ndx-2 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
33	nhr-63	C06C6.4	n/a	chrV 16,003,610	C. elegans NHR-63 protein; contains similarity to Pfam domains PF00104 (Ligand-binding domain of nuclear hormone receptor) , PF00105 (Zinc finger, C4 type (two domains)) contains similarity to Interpro domains IPR008946 (Nuclear hormone receptor, ligand-binding), IPR013088 (Zinc finger, NHR/GATA-type), IPR001628 (Zinc finger, nuclear hormone receptor-type), IPR000536 (Nuclear hormone receptor, ligand-binding, core)
34	T23G4.4	T23G4.4	n/a	chrIV 13,675,781	contains similarity to Pfam domain PF01757 Acyltransferase family contains similarity to Interpro domain IPR002656 (Acyltransferase 3)
35	F58B4.2	F58B4.2	n/a	chrV 10,918,030	contains similarity to Pfam domain PF00173 Cytochrome b5-like Heme/Steroid binding domain contains similarity to Interpro domain IPR001199 (Cytochrome b5)
36	Y41C4A.1	Y41C4A.1	n/a	chrIII 11,648,712	contains similarity to Oryza sativa Putative aspartate kinase.; TR:Q851Z6
37	F25E5.7	F25E5.7	n/a	chrV 7,440,782	contains similarity to Pfam domain PF03761 Domain of unknown function (DUF316) contains similarity to Interpro domains IPR001254 (Peptidase S1 and S6, chymotrypsin/Hap), IPR005514 (Protein of unknown function DUF316), IPR009003 (Peptidase, trypsin-like serine and cysteine)
38	C33E10.6	C33E10.6	n/a	chrX 17,268,242	contains similarity to Tetrahymena thermophila SB210 Putative uncharacterized protein.; TR:Q227I5
39	K07E12.2	K07E12.2	n/a	chrIII 6,737,547
40	F28B1.1	F28B1.1	n/a	chrV 17,043,156	contains similarity to Mus musculus Hypothetical protein.; TR:Q8C3I4
41	T02G6.2	T02G6.2	n/a	chrI 11,801,906	contains similarity to Arabidopsis thaliana Hypothetical protein.; TR:Q9C9Y9
42	fbxa-223	ZC513.10	n/a	chrV 8,064,176	fbxa-223 encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; FBXA-223 also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
43	C55A6.6	C55A6.6	n/a	chrV 11,514,222	contains similarity to Pfam domain PF00106 short chain dehydrogenase contains similarity to Interpro domains IPR002424 (Insect alcohol dehydrogenase family), IPR002347 (Glucose/ribitol dehydrogenase), IPR002198 (Short-chain dehydrogenase/reductase SDR), IPR016040 (NAD(P)-binding)
44	C03B1.6	C03B1.6	n/a	chrX 6,350,637
45	F38H4.3	F38H4.3	n/a	chrIV 11,845,293	contains similarity to Interpro domain IPR000694 (Proline-rich region)
46	C50D2.6	C50D2.6	n/a	chrII 86,096
47	F54D12.2	F54D12.2	n/a	chrII 1,399,803	contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domain IPR006583 (CW)
48	F46F5.11	F46F5.11	n/a	chrII 810,328	contains similarity to Pfam domain PF03385 Protein of unknown function, DUF288 contains similarity to Interpro domain IPR005049 (Protein of unknown function DUF288)
49	K06B4.3	K06B4.3	n/a	chrV 15,672,799	contains similarity to Saccharomyces cerevisiae mRNA binding protein; SGD:YPR042C
50	K02H8.1	K02H8.1	n/a	chrX 17,004,963	K02H8.1 encodes, by alternative splicing, two isoforms of a putative MUSCLEBLIND-type mRNA splicing regulator required in adults for normal muscle dense body organization, locomotion, and vulval morphogenesis; K02H8.1 is orthologous to Drosophila MBL and human MBNL1 (OMIM:606516), MBNL2 (OMIM:607327), and MBNL3 (OMIM:300413); K02H8.1 is transcribed in larvae and adults; K02H8.1(RNAi) animals show protruding vulvae, progressive uncoordination, and disordered dense bodies; while K02H8.1 is required in adults, it is dispensable in larvae, perhaps reflecting a progressive muscle dystrophy in K02H8.1(RNAi) animals.