UCSC C. elegans Gene Sorter

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UCSC C. elegans Gene Sorter

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#	Name	WormBase	BLASTP E-Value	Genome Position	Description
1	F35F10.14	F35F10.14	2e-18	chrV 3,319,580
2	T26E4.5	T26E4.5	n/a	chrV 15,787,827	contains similarity to Interpro domain IPR008996 ()
3	apx-1	K08D9.3	n/a	chrV 3,216,670	apx-1 encodes one of ten C. elegans DSL (Delta, Serrate, LAG-2) proteins, integral transmembrane and secreted proteins that function as signaling ligands for the Notch family receptors GLP-1 and LIN-12; in the 4-cell embryo, maternally supplied APX-1 functions as a GLP-1 ligand for an inductive interaction that specifies the fate of the ABp blastomere; later in embryogenesis, APX-1 is required for formation of the LIN-12-dependent, invariant asymmetrical twist that occurs as part of normal gut morphogenesis; during larval development, APX-1 is required redundantly with DSL-1 and LAG-2 for the LIN-12-mediated lateral signal that spatially patterns the primary and secondary vulval cell lineages; in the early embryo, APX-1 is first detected at the anterior edge of the P1 blastomere, with later expression visible in P2 at sites of contact with ABp, and in the cytoplasm of the EMS and P3 blastomeres; expression in the vulval precursor cells (VPCs) is detected in the primary VPC, P6.p, and its descendants; embryonic APX-1 expression is dependent upon PIE-1 activity, while later vulval expression is mediated by the Ras signaling pathway and the SUR-2 transcriptional cofactor.
4	ptr-13	K07C10.1	n/a	chrII 11,159,735	ptr-13 encodes a nematode-specific member of the sterol sensing domain (SSD) proteins, distantly paralogous to Drosophila PATCHED (PTC) and human PTCH (OMIM:601309, mutated in basal cell nevus syndrome); PTR-13 is weakly required for normal molting from L4 to adult stages; PTR-13 is also required for normal growth to full size and locomotion.
5	W04C9.6	W04C9.6	n/a	chrI 485,237	contains similarity to Pfam domain PF07690 Major Facilitator Superfamily contains similarity to Interpro domains IPR000694 (Proline-rich region), IPR011701 (Major facilitator superfamily MFS-1), IPR016196 (MFS general substrate transporter)
6	R10E11.9	R10E11.9	n/a	chrIII 9,792,971	contains similarity to Brachydanio rerio Hypothetical protein.; TR:Q7T2Z9
7	Y79H2A.4	Y79H2A.4	n/a	chrIII 12,041,576	contains similarity to Interpro domains IPR012677 (Nucleotide-binding, alpha-beta plait), IPR000504 (RNA recognition motif, RNP-1)
8	srd-41	F17A2.6	n/a	chrX 12,327,467	C. elegans SRD-41 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR003006 (Immunoglobulin/major histocompatibility complex, conserved site)
9	B0250.2	B0250.2	n/a	chrV 20,473,310	contains similarity to Drosophila erecta Female-specific transformer protein.; SW:TRSF_DROER
10	C45E5.3	C45E5.3	n/a	chrIV 5,740,334	contains similarity to Pfam domain PF00704 Glycosyl hydrolases family 18 contains similarity to Interpro domains IPR011583 (Chitinase II), IPR017853 (Glycoside hydrolase, catalytic core), IPR001223 (Glycoside hydrolase, family 18, catalytic domain), IPR013781 (Glycoside hydrolase, subgroup, catalytic core), IPR001574 (Ribosome-inactivating protein)
11	Y116A8C.9	Y116A8C.9	n/a	chrIV 16,943,608	contains similarity to Danio rerio Transmembrane protein 185-like.; SW:Q7SYC7
12	C44H4.6	C44H4.6	n/a	chrX 14,597,741	contains similarity to Pfam domain PF00069 Protein kinase domain contains similarity to Interpro domains IPR017441 (Protein kinase ATP binding, conserved site), IPR002290 (Serine/threonine protein kinase), IPR011009 (Protein kinase-like), IPR008271 (Serine/threonine protein kinase, active site), IPR000719 (Protein kinase, core), IPR001245 (Tyrosine protein kinase), IPR017442 (Serine/threonine protein kinase-related)
13	str-122	W03D2.10	n/a	chrIV 4,067,151	C. elegans STR-122 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
14	sre-30	F57G9.2	n/a	chrII 12,405,637	C. elegans SRE-30 protein; contains similarity to Pfam domain PF03125 C. elegans Sre G protein-coupled chemoreceptor contains similarity to Interpro domain IPR004151 (C. elegans Sre G protein-coupled chemoreceptor)
15	K08D10.11	K08D10.11	n/a	chrIV 4,185,528
16	T26C12.2	T26C12.2	n/a	chrIV 3,264,607	contains similarity to Interpro domain IPR001991 (Sodium:dicarboxylate symporter)
17	sri-69	Y102A5C.32	n/a	chrV 17,007,786	C. elegans SRI-69 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
18	immp-1	C24H11.6	n/a	chrIII 11,775,731	C. elegans IMMP-1 protein; contains similarity to Pfam domain PF00717 Peptidase S24-like contains similarity to Interpro domains IPR001733 (Peptidase S26B, eukaryotic signal peptidase), IPR015927 (Peptidase S24, S26A, S26B and S26C), IPR014037 (Peptidase S26A), IPR011056 (Peptidase S24, S26A and S26B, C-terminal), IPR000223 (Peptidase S26A, signal peptidase I)
19	F32D1.8	F32D1.8	n/a	chrV 4,377,156
20	T23D5.3	T23D5.3	n/a	chrV 15,733,239	contains similarity to Pfam domain PF03436 Domain of unknown function (DUF281) contains similarity to Interpro domains IPR000104 (Antifreeze protein, type I), IPR001859 (Ribosomal protein P2), IPR005098 (Protein of unknown function DUF281)
21	fbxa-45	F09C6.6	n/a	chrV 16,898,926	This gene encodes a protein containing an F-box, a motif predicted to mediate protein-protein interactions either with homologs of yeast Skp-1p or with other proteins; this gene's encoded protein also contains an FTH/DUF38 motif, which may also mediate protein-protein interaction.
22	C03B1.10	C03B1.10	n/a	chrX 6,357,809	contains similarity to Homo sapiens cDNA FLJ42885 fis, clone BRHIP3007586; HI:HIT000044748
23	sru-25	F31F4.14	n/a	chrV 673,072	C. elegans SRU-25 protein; contains similarity to Pfam domain PF02688 Domain of unknown function DUF215 contains similarity to Interpro domain IPR003839 (Protein of unknown function DUF215)
24	C03B1.9	C03B1.9	n/a	chrX 6,346,694
25	F20H11.6	F20H11.6	n/a	chrIII 6,599,869
26	grl-1	C24G6.7	n/a	chrV 5,532,342	grl-1 encodes a hedgehog-like protein, with an N-terminal signal sequence, a central proline-rich region, and a C-terminal Ground-like (Grl) domain; GRL-1 is expressed in intestine, neurons, and larval arcade cells; the Grl domain is predicted to form a cysteine-crosslinked protein involved in intercellular signalling, and it has subtle similarity to the N-terminal Hedge domain of HEDGEHOG proteins.
27	srh-136	F36D3.6	n/a	chrV 16,496,767	C. elegans SRH-136 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
28	str-257	C01B4.1	n/a	chrV 2,519,650	C. elegans STR-257 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
29	Y75B8A.32	Y75B8A.32	n/a	chrIII 12,356,632	contains similarity to Danio rerio PERQ amino acid-rich with GYF domain-containing protein 2s(Trinucleotide repeat-containing gene 15 protein).; SW:Q4KME6
30	sri-9	Y102A5C.29	n/a	chrV 17,002,496	C. elegans SRI-9 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domains IPR003002 (7TM chemoreceptor, subfamily 1), IPR000565 (DNA topoisomerase, type IIA, subunit B)
31	str-113	Y39H10B.1	n/a	chrV 3,665,916	C. elegans STR-113 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
32	srj-22	F28H7.1	n/a	chrV 10,743,082	C. elegans SRJ-22 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
33	C50F2.4	C50F2.4	n/a	chrI 3,890,325
34	srt-3	F47D2.3	n/a	chrV 4,259,059	C. elegans SRT-3 protein; contains similarity to Pfam domain PF01748 Caenorhabditis serpentine receptor-like protein contains similarity to Interpro domain IPR002651 (Protein of unknown function DUF32)
35	nas-18	K03B8.3	n/a	chrV 11,396,823	nas-18 encodes an astacin-like metalloprotease; loss of nas-18 activity via RNAi results in a reduction of fat content suggesting an abnormality in lipid metabolism.
36	clec-120	F29A7.7	n/a	chrII 2,756,519	C. elegans CLEC-120 protein; contains similarity to Pfam domain PF08277 PAN-like domain contains similarity to Interpro domains IPR006583 (CW), IPR016187 (C-type lectin fold)
37	srsx-27	C51E3.2	n/a	chrV 10,151,415	C. elegans SRSX-27 protein; contains similarity to Pfam domain PF00001 7 transmembrane receptor (rhodopsin family) contains similarity to Interpro domains IPR017452 (GPCR, rhodopsin-like superfamily), IPR000276 (GPCR, rhodopsin-like)
38	str-240	K02H11.2	n/a	chrV 1,521,205	C. elegans STR-240 protein; contains similarity to Pfam domain PF01461 7TM chemoreceptor contains similarity to Interpro domain IPR003002 (7TM chemoreceptor, subfamily 1)
39	srg-59	C24B9.7	n/a	chrV 2,724,113	C. elegans SRG-59 protein; contains similarity to Interpro domain IPR000609 (Serpentine gamma receptor, Caenorhabditis species)
40	srw-1	Y75B12B.7	n/a	chrV 15,198,801	C. elegans SRW-1 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
41	Y56A3A.33	Y56A3A.33	n/a	chrIII 12,001,104	contains similarity to Pfam domain PF00929 Exonuclease contains similarity to Interpro domains IPR013520 (Exonuclease, RNase T and DNA polymerase III), IPR006055 (Exonuclease), IPR012337 (Polynucleotidyl transferase, Ribonuclease H fold)
42	cnc-5	R09B5.10	n/a	chrV 1,445,607	cnc-5 encodes one of six C. elegans caenacin peptides; CNC-5 is predicted to be a secreted protein that, based upon similarity to CNC-2, -4, and -6, may function as an antimicrobial peptide in the innate immune response.
43	F55A4.4	F55A4.4	n/a	chrX 1,025,409	contains similarity to Pfam domain PF00035 Double-stranded RNA binding motif contains similarity to Interpro domains IPR001159 (Double-stranded RNA binding), IPR014720 (Double-stranded RNA-binding-like)
44	athp-1	C44B9.4	n/a	chrIII 10,887,899	C. elegans ATHP-1 protein; contains similarity to Pfam domains PF02178 (AT hook motif) (2), PF00628 (PHD-finger) contains similarity to Interpro domains IPR008984 (SMAD/FHA domain), IPR001965 (Zinc finger, PHD-type), IPR000637 (HMG-I and HMG-Y, DNA-binding), IPR013083 (Zinc finger, RING/FYVE/PHD-type), IPR000294 (Vitamin K-dependent carboxylation/gamma-carboxyglutamic region), IPR000253 (Forkhead-associated), IPR011011 (Zinc finger, FYVE/PHD-type)
45	T20B12.5	T20B12.5	n/a	chrIII 7,366,839
46	srw-139	C44C3.7	n/a	chrV 2,984,742	C. elegans SRW-139 protein; contains similarity to Interpro domain IPR017452 (GPCR, rhodopsin-like superfamily)
47	C56E6.4	C56E6.4	n/a	chrII 6,527,652	contains similarity to Pfam domain PF03607 Doublecortin contains similarity to Interpro domain IPR003533 (Doublecortin)
48	F48C1.3	F48C1.3	n/a	chrI 5,314,472
49	Y56A3A.11	Y56A3A.11	n/a	chrIII 11,896,407	contains similarity to Pfam domain PF01974 tRNA intron endonuclease, catalytic C-terminal domain contains similarity to Interpro domains IPR006677 (tRNA intron endonuclease, catalytic domain-like), IPR011856 (Endonuclease TnsA, N-terminal/resolvase Hjc/tRNA endonuclease, C-terminal)
50	srv-8	F53F1.7	n/a	chrV 13,419,959	C. elegans SRV-8 protein; contains similarity to Interpro domains IPR002456 (GPCR, family 3, gamma-aminobutyric acid receptor, type B1), IPR002455 (GPCR, family 3, gamma-aminobutyric acid receptor, type B)